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PMC:7408073 / 88196-89255 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T493 79-83 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T494 495-499 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T174 79-83 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T175 415-418 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T176 495-499 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3076 314-317 Gene denotes ACE Gene:59272
3077 469-473 Gene denotes ACE2 Gene:59272
3078 521-525 Gene denotes AT1R Gene:185
3079 580-584 Gene denotes ACE2 Gene:59272
3080 669-673 Gene denotes ACE2 Gene:59272
3081 34-42 Species denotes patients Tax:9606
3082 278-287 Species denotes SARS-CoVs Tax:694009
3083 291-296 Species denotes human Tax:9606
3084 297-312 Species denotes influenza virus Tax:11308
3085 387-393 Species denotes humans Tax:9606
3086 663-668 Species denotes human Tax:9606
3087 910-918 Species denotes patients Tax:9606
3088 514-520 Gene denotes Ang II Gene:24179
3089 29-33 Disease denotes ARDS MESH:D012128
3090 116-125 Disease denotes hypoxemia MESH:D000860
3091 127-131 Disease denotes ARDS MESH:D012128
3092 193-199 Disease denotes sepsis MESH:D018805
3093 201-207 Disease denotes trauma MESH:D014947
3094 209-227 Disease denotes acute pancreatitis MESH:D010195
3095 232-242 Disease denotes pneumonias MESH:D011014
3096 253-269 Disease denotes virus infections MESH:D001102
3097 379-383 Disease denotes ARDS MESH:D012128
3098 440-444 Disease denotes ARDS MESH:D012128
3099 588-592 Disease denotes ARDS MESH:D012128
3100 782-786 Disease denotes ARDS MESH:D012128
3101 901-909 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T509 29-33 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T510 127-131 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T511 201-207 Disease denotes trauma http://purl.obolibrary.org/obo/MONDO_0021178
T512 209-227 Disease denotes acute pancreatitis http://purl.obolibrary.org/obo/MONDO_0006515
T513 215-227 Disease denotes pancreatitis http://purl.obolibrary.org/obo/MONDO_0004982
T514 232-242 Disease denotes pneumonias http://purl.obolibrary.org/obo/MONDO_0005249
T515 253-269 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T516 278-282 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T517 297-306 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T518 379-383 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T519 440-444 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T520 588-592 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T521 782-786 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T522 835-838 Disease denotes PAH http://purl.obolibrary.org/obo/MONDO_0015924
T523 901-909 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1064 79-83 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T1065 79-83 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T1066 253-258 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1067 291-296 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1068 307-312 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1069 387-393 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T1070 430-431 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1071 454-460 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T1072 495-499 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T1073 495-499 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T1074 526-534 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T1075 593-596 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1076 663-668 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1077 772-778 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T51967 175-180 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T99879 415-418 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T49537 518-520 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T372 835-838 Chemical denotes PAH http://purl.obolibrary.org/obo/CHEBI_104011|http://purl.obolibrary.org/obo/CHEBI_31204|http://purl.obolibrary.org/obo/CHEBI_33848|http://purl.obolibrary.org/obo/CHEBI_53305

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T429 0-126 Sentence denotes The main clinical feature of ARDS patients is the progressive deterioration of lung function leading to progressive hypoxemia.
T430 127-313 Sentence denotes ARDS can be induced by different causes such as ZnCl2 aspiration, sepsis, trauma, acute pancreatitis, or pneumonias following virus infections such as SARS-CoVs or human influenza virus.
T431 314-450 Sentence denotes ACE insertion/deletion polymorphisms correlated with severity of ARDS in humans, suggesting that the RAS could have a role in ARDS [44].
T432 451-629 Sentence denotes In animal models, ACE2 protected from acute lung by inhibiting Ang II/AT1R activity [15], for this reason the use of recombinant ACE2 in ARDS has been proposed and pursued [134].
T433 630-960 Sentence denotes Clinical trials with recombinant human ACE2 started in healthy volunteers in 2009 (ClinicalTrials.gov number, NCT00886353 [178]), then it was tested in ARDS (ClinicalTrials.gov number, NCT01597635 [134]), PAH (ClinicalTrials.gov number, NCT01884051 [108]) and finally in COVID-19 patients (ClinicalTrials.gov number, NCT04287686).
T434 961-1059 Sentence denotes Despite its safe use, no conclusive evidence in support of its use in these diseases was reported.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T153 116-125 Phenotype denotes hypoxemia http://purl.obolibrary.org/obo/HP_0012418
T154 181-191 Phenotype denotes aspiration http://purl.obolibrary.org/obo/HP_0002835
T155 193-199 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T156 209-227 Phenotype denotes acute pancreatitis http://purl.obolibrary.org/obo/HP_0001735
T157 232-242 Phenotype denotes pneumonias http://purl.obolibrary.org/obo/HP_0002090

2_test

Id Subject Object Predicate Lexical cue
32708755-20599443-20678981 446-448 20599443 denotes 44
32708755-16001071-20678982 536-538 16001071 denotes 15
32708755-28877748-20678983 624-627 28877748 denotes 134
32708755-23681967-20678984 753-756 23681967 denotes 178
32708755-28877748-20678985 828-831 28877748 denotes 134
32708755-29903860-20678986 880-883 29903860 denotes 108