PMC:7408073 / 86422-86942 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T483","span":{"begin":33,"end":38},"obj":"Body_part"},{"id":"T484","span":{"begin":184,"end":200},"obj":"Body_part"},{"id":"T485","span":{"begin":195,"end":200},"obj":"Body_part"},{"id":"T486","span":{"begin":450,"end":456},"obj":"Body_part"}],"attributes":[{"id":"A483","pred":"fma_id","subj":"T483","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A484","pred":"fma_id","subj":"T484","obj":"http://purl.org/sig/ont/fma/fma67653"},{"id":"A485","pred":"fma_id","subj":"T485","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A486","pred":"fma_id","subj":"T486","obj":"http://purl.org/sig/ont/fma/fma62970"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T168","span":{"begin":33,"end":38},"obj":"Body_part"},{"id":"T169","span":{"begin":208,"end":214},"obj":"Body_part"}],"attributes":[{"id":"A168","pred":"uberon_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A169","pred":"uberon_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-PubTator","denotations":[{"id":"2984","span":{"begin":42,"end":46},"obj":"Gene"},{"id":"2985","span":{"begin":165,"end":169},"obj":"Gene"},{"id":"2986","span":{"begin":279,"end":289},"obj":"Gene"},{"id":"2987","span":{"begin":429,"end":433},"obj":"Gene"},{"id":"2988","span":{"begin":6,"end":14},"obj":"Gene"},{"id":"2989","span":{"begin":309,"end":317},"obj":"Species"},{"id":"2990","span":{"begin":124,"end":130},"obj":"Gene"},{"id":"2991","span":{"begin":300,"end":308},"obj":"Disease"}],"attributes":[{"id":"A2984","pred":"tao:has_database_id","subj":"2984","obj":"Gene:59272"},{"id":"A2985","pred":"tao:has_database_id","subj":"2985","obj":"Gene:116511"},{"id":"A2986","pred":"tao:has_database_id","subj":"2986","obj":"Gene:3827"},{"id":"A2987","pred":"tao:has_database_id","subj":"2987","obj":"Gene:59272"},{"id":"A2988","pred":"tao:has_database_id","subj":"2988","obj":"Gene:284"},{"id":"A2989","pred":"tao:has_database_id","subj":"2989","obj":"Tax:9606"},{"id":"A2990","pred":"tao:has_database_id","subj":"2990","obj":"Gene:24179"},{"id":"A2991","pred":"tao:has_database_id","subj":"2991","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T494","span":{"begin":300,"end":308},"obj":"Disease"}],"attributes":[{"id":"A494","pred":"mondo_id","subj":"T494","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1035","span":{"begin":33,"end":38},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T1036","span":{"begin":33,"end":38},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T1037","span":{"begin":195,"end":200},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T1038","span":{"begin":208,"end":214},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T1039","span":{"begin":434,"end":442},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T1040","span":{"begin":450,"end":456},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T1041","span":{"begin":471,"end":472},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T52995","span":{"begin":128,"end":130},"obj":"Chemical"},{"id":"T40147","span":{"begin":258,"end":269},"obj":"Chemical"},{"id":"T54329","span":{"begin":279,"end":289},"obj":"Chemical"}],"attributes":[{"id":"A42084","pred":"chebi_id","subj":"T52995","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A1101","pred":"chebi_id","subj":"T40147","obj":"http://purl.obolibrary.org/obo/CHEBI_25212"},{"id":"A64187","pred":"chebi_id","subj":"T54329","obj":"http://purl.obolibrary.org/obo/CHEBI_3165"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T154","span":{"begin":236,"end":257},"obj":"http://purl.obolibrary.org/obo/GO_0014863"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}

{"project":"LitCovid-sentences","denotations":[{"id":"T423","span":{"begin":216,"end":457},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"mple, Ang (1–7) concentration in blood by ACE2 pathway upregulation is dependent both on the increase of the (antagonistic) Ang II (and its precursor, Ang I) and on MasR expression on surface of cells in the organs. To this regard, the detection of inactive metabolites, such as bradykinin (1–7), in COVID-19 patients and comparison with its concentration in healthy subjects could be the most indicative and reliable markers of ACE2 activity in the plasma.\nOf interest, a report that described the ex vivo effect of hum"}