PMC:7408073 / 85836-86128 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T481","span":{"begin":114,"end":120},"obj":"Body_part"},{"id":"T482","span":{"begin":201,"end":207},"obj":"Body_part"}],"attributes":[{"id":"A481","pred":"fma_id","subj":"T481","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A482","pred":"fma_id","subj":"T482","obj":"http://purl.org/sig/ont/fma/fma62970"}],"text":"In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T167","span":{"begin":95,"end":98},"obj":"Body_part"}],"attributes":[{"id":"A167","pred":"uberon_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PubTator","denotations":[{"id":"2934","span":{"begin":33,"end":36},"obj":"Gene"},{"id":"2935","span":{"begin":37,"end":41},"obj":"Gene"},{"id":"2936","span":{"begin":175,"end":179},"obj":"Gene"},{"id":"2937","span":{"begin":261,"end":264},"obj":"Gene"},{"id":"2938","span":{"begin":265,"end":269},"obj":"Gene"},{"id":"2939","span":{"begin":230,"end":235},"obj":"Chemical"}],"attributes":[{"id":"A2934","pred":"tao:has_database_id","subj":"2934","obj":"Gene:59272"},{"id":"A2935","pred":"tao:has_database_id","subj":"2935","obj":"Gene:59272"},{"id":"A2936","pred":"tao:has_database_id","subj":"2936","obj":"Gene:59272"},{"id":"A2937","pred":"tao:has_database_id","subj":"2937","obj":"Gene:59272"},{"id":"A2938","pred":"tao:has_database_id","subj":"2938","obj":"Gene:59272"},{"id":"A2939","pred":"tao:has_database_id","subj":"2939","obj":"MESH:C016837"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1027","span":{"begin":42,"end":50},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T1028","span":{"begin":114,"end":120},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T1029","span":{"begin":201,"end":207},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T1030","span":{"begin":209,"end":212},"obj":"http://purl.obolibrary.org/obo/CLO_0001046"},{"id":"T1031","span":{"begin":278,"end":286},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T30551","span":{"begin":95,"end":98},"obj":"Chemical"},{"id":"T24736","span":{"begin":175,"end":189},"obj":"Chemical"},{"id":"T58502","span":{"begin":180,"end":189},"obj":"Chemical"},{"id":"T53764","span":{"begin":230,"end":235},"obj":"Chemical"}],"attributes":[{"id":"A35372","pred":"chebi_id","subj":"T30551","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A13957","pred":"chebi_id","subj":"T24736","obj":"http://purl.obolibrary.org/obo/CHEBI_147289"},{"id":"A81135","pred":"chebi_id","subj":"T58502","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A10647","pred":"chebi_id","subj":"T53764","obj":"http://purl.obolibrary.org/obo/CHEBI_49976"}],"text":"In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"2_test","denotations":[{"id":"32708755-18223027-20678975","span":{"begin":209,"end":212},"obj":"18223027"},{"id":"32708755-25813276-20678976","span":{"begin":288,"end":290},"obj":"25813276"}],"text":"In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}