PMC:7408073 / 85832-86128 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T481","span":{"begin":118,"end":124},"obj":"Body_part"},{"id":"T482","span":{"begin":205,"end":211},"obj":"Body_part"}],"attributes":[{"id":"A481","pred":"fma_id","subj":"T481","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A482","pred":"fma_id","subj":"T482","obj":"http://purl.org/sig/ont/fma/fma62970"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T167","span":{"begin":99,"end":102},"obj":"Body_part"}],"attributes":[{"id":"A167","pred":"uberon_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PubTator","denotations":[{"id":"2934","span":{"begin":37,"end":40},"obj":"Gene"},{"id":"2935","span":{"begin":41,"end":45},"obj":"Gene"},{"id":"2936","span":{"begin":179,"end":183},"obj":"Gene"},{"id":"2937","span":{"begin":265,"end":268},"obj":"Gene"},{"id":"2938","span":{"begin":269,"end":273},"obj":"Gene"},{"id":"2939","span":{"begin":234,"end":239},"obj":"Chemical"}],"attributes":[{"id":"A2934","pred":"tao:has_database_id","subj":"2934","obj":"Gene:59272"},{"id":"A2935","pred":"tao:has_database_id","subj":"2935","obj":"Gene:59272"},{"id":"A2936","pred":"tao:has_database_id","subj":"2936","obj":"Gene:59272"},{"id":"A2937","pred":"tao:has_database_id","subj":"2937","obj":"Gene:59272"},{"id":"A2938","pred":"tao:has_database_id","subj":"2938","obj":"Gene:59272"},{"id":"A2939","pred":"tao:has_database_id","subj":"2939","obj":"MESH:C016837"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1027","span":{"begin":46,"end":54},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T1028","span":{"begin":118,"end":124},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T1029","span":{"begin":205,"end":211},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T1030","span":{"begin":213,"end":216},"obj":"http://purl.obolibrary.org/obo/CLO_0001046"},{"id":"T1031","span":{"begin":282,"end":290},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T30551","span":{"begin":99,"end":102},"obj":"Chemical"},{"id":"T24736","span":{"begin":179,"end":193},"obj":"Chemical"},{"id":"T58502","span":{"begin":184,"end":193},"obj":"Chemical"},{"id":"T53764","span":{"begin":234,"end":239},"obj":"Chemical"}],"attributes":[{"id":"A35372","pred":"chebi_id","subj":"T30551","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A13957","pred":"chebi_id","subj":"T24736","obj":"http://purl.obolibrary.org/obo/CHEBI_147289"},{"id":"A81135","pred":"chebi_id","subj":"T58502","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A10647","pred":"chebi_id","subj":"T53764","obj":"http://purl.obolibrary.org/obo/CHEBI_49976"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"LitCovid-sentences","denotations":[{"id":"T419","span":{"begin":0,"end":296},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}

{"project":"2_test","denotations":[{"id":"32708755-18223027-20678975","span":{"begin":213,"end":216},"obj":"18223027"},{"id":"32708755-25813276-20678976","span":{"begin":292,"end":294},"obj":"25813276"}],"text":"(3) In order to evaluate circulating ACE/ACE2 activity, we can determine it by adding fluorogenic (RAS) substrates to plasma samples without (thus considering also the endogenous ACE2 inhibitor present in plasma [116]) or with adding ZnCl2, which is able to induce ACE/ACE2 maximal activity [96];"}