PMC:7408073 / 75223-75554 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"2577","span":{"begin":93,"end":97},"obj":"Gene"},{"id":"2578","span":{"begin":109,"end":115},"obj":"Gene"},{"id":"2579","span":{"begin":157,"end":165},"obj":"Gene"},{"id":"2580","span":{"begin":284,"end":288},"obj":"Gene"},{"id":"2581","span":{"begin":289,"end":292},"obj":"Gene"},{"id":"2582","span":{"begin":138,"end":146},"obj":"Gene"},{"id":"2599","span":{"begin":50,"end":58},"obj":"Species"},{"id":"2631","span":{"begin":41,"end":49},"obj":"Disease"}],"attributes":[{"id":"A2577","pred":"tao:has_database_id","subj":"2577","obj":"Gene:59272"},{"id":"A2578","pred":"tao:has_database_id","subj":"2578","obj":"Gene:24179"},{"id":"A2579","pred":"tao:has_database_id","subj":"2579","obj":"Gene:284"},{"id":"A2580","pred":"tao:has_database_id","subj":"2580","obj":"Gene:59272"},{"id":"A2581","pred":"tao:has_database_id","subj":"2581","obj":"Gene:59272"},{"id":"A2582","pred":"tao:has_database_id","subj":"2582","obj":"Gene:284"},{"id":"A2599","pred":"tao:has_database_id","subj":"2599","obj":"Tax:9606"},{"id":"A2631","pred":"tao:has_database_id","subj":"2631","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"A possible beneficial effect of ACEIs in COVID-19 patients could indirectly come by reducing ACE2 substrate, Ang II, and finally limiting Ang (1–7) [but not Ang (1–9)] production and its (detrimental) effects; however, this is only a hypothetical possibility since, in this case, the ACE2/ACE pathway might be even more unbalanced."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T377","span":{"begin":41,"end":49},"obj":"Disease"}],"attributes":[{"id":"A377","pred":"mondo_id","subj":"T377","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"A possible beneficial effect of ACEIs in COVID-19 patients could indirectly come by reducing ACE2 substrate, Ang II, and finally limiting Ang (1–7) [but not Ang (1–9)] production and its (detrimental) effects; however, this is only a hypothetical possibility since, in this case, the ACE2/ACE pathway might be even more unbalanced."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T911","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T912","span":{"begin":232,"end":233},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"A possible beneficial effect of ACEIs in COVID-19 patients could indirectly come by reducing ACE2 substrate, Ang II, and finally limiting Ang (1–7) [but not Ang (1–9)] production and its (detrimental) effects; however, this is only a hypothetical possibility since, in this case, the ACE2/ACE pathway might be even more unbalanced."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T31128","span":{"begin":32,"end":37},"obj":"Chemical"},{"id":"T305","span":{"begin":113,"end":115},"obj":"Chemical"}],"attributes":[{"id":"A18946","pred":"chebi_id","subj":"T31128","obj":"http://purl.obolibrary.org/obo/CHEBI_35457"},{"id":"A72079","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"A possible beneficial effect of ACEIs in COVID-19 patients could indirectly come by reducing ACE2 substrate, Ang II, and finally limiting Ang (1–7) [but not Ang (1–9)] production and its (detrimental) effects; however, this is only a hypothetical possibility since, in this case, the ACE2/ACE pathway might be even more unbalanced."}

{"project":"LitCovid-sentences","denotations":[{"id":"T371","span":{"begin":0,"end":331},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A possible beneficial effect of ACEIs in COVID-19 patients could indirectly come by reducing ACE2 substrate, Ang II, and finally limiting Ang (1–7) [but not Ang (1–9)] production and its (detrimental) effects; however, this is only a hypothetical possibility since, in this case, the ACE2/ACE pathway might be even more unbalanced."}