PMC:7408073 / 6859-7378 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T62408","span":{"begin":124,"end":128},"obj":"Body_part"},{"id":"T81532","span":{"begin":167,"end":172},"obj":"Body_part"},{"id":"T50862","span":{"begin":446,"end":466},"obj":"Body_part"},{"id":"T15477","span":{"begin":456,"end":466},"obj":"Body_part"}],"attributes":[{"id":"A11456","pred":"fma_id","subj":"T62408","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A9532","pred":"fma_id","subj":"T81532","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A66472","pred":"fma_id","subj":"T50862","obj":"http://purl.org/sig/ont/fma/fma67782"},{"id":"A28929","pred":"fma_id","subj":"T15477","obj":"http://purl.org/sig/ont/fma/fma9639"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T11","span":{"begin":446,"end":466},"obj":"Body_part"},{"id":"T12","span":{"begin":456,"end":466},"obj":"Body_part"}],"attributes":[{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0002031"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0000483"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}

{"project":"LitCovid-PubTator","denotations":[{"id":"255","span":{"begin":143,"end":147},"obj":"Gene"},{"id":"256","span":{"begin":308,"end":312},"obj":"Gene"},{"id":"257","span":{"begin":421,"end":425},"obj":"Gene"},{"id":"275","span":{"begin":151,"end":156},"obj":"Species"},{"id":"276","span":{"begin":187,"end":195},"obj":"Species"},{"id":"300","span":{"begin":173,"end":181},"obj":"Disease"},{"id":"301","span":{"begin":232,"end":241},"obj":"Disease"},{"id":"302","span":{"begin":362,"end":371},"obj":"Disease"}],"attributes":[{"id":"A255","pred":"tao:has_database_id","subj":"255","obj":"Gene:59272"},{"id":"A256","pred":"tao:has_database_id","subj":"256","obj":"Gene:59272"},{"id":"A257","pred":"tao:has_database_id","subj":"257","obj":"Gene:59272"},{"id":"A275","pred":"tao:has_database_id","subj":"275","obj":"Tax:9606"},{"id":"A276","pred":"tao:has_database_id","subj":"276","obj":"Tax:694009"},{"id":"A300","pred":"tao:has_database_id","subj":"300","obj":"MESH:D007239"},{"id":"A301","pred":"tao:has_database_id","subj":"301","obj":"MESH:D007239"},{"id":"A302","pred":"tao:has_database_id","subj":"302","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T75","span":{"begin":187,"end":195},"obj":"Disease"},{"id":"T76","span":{"begin":187,"end":191},"obj":"Disease"},{"id":"T77","span":{"begin":232,"end":241},"obj":"Disease"},{"id":"T78","span":{"begin":362,"end":371},"obj":"Disease"}],"attributes":[{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A76","pred":"mondo_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A77","pred":"mondo_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T95692","span":{"begin":39,"end":47},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T65495","span":{"begin":64,"end":65},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T74464","span":{"begin":124,"end":128},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T56108","span":{"begin":151,"end":156},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T38701","span":{"begin":167,"end":172},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T36055","span":{"begin":258,"end":259},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T77642","span":{"begin":332,"end":333},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T15238","span":{"begin":401,"end":404},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T38031","span":{"begin":456,"end":466},"obj":"http://purl.obolibrary.org/obo/UBERON_0000483"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T51579","span":{"begin":124,"end":139},"obj":"http://purl.obolibrary.org/obo/GO_0010467"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}

{"project":"LitCovid-sentences","denotations":[{"id":"T36","span":{"begin":49,"end":377},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"inly enhances its circulating/systemic activity. Interestingly, a recent integrative bioinformatics analysis shows that the gene expression of ACE2 in human bronchial cells infected with SARS-CoV is dramatically increased 24h after infection and remained at a high level for at least 2 days, suggesting that ACE2 may be involved in a positive feedback loop post-infection [25]. In the same report, it has been shown that ACE2 expression level in bronchial epithelium obtained by brushing from asthmatic and normal subje"}