PMC:7408073 / 6379-6749 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T57345","span":{"begin":156,"end":163},"obj":"Body_part"},{"id":"T54062","span":{"begin":250,"end":265},"obj":"Body_part"}],"attributes":[{"id":"A3717","pred":"fma_id","subj":"T57345","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A19160","pred":"fma_id","subj":"T54062","obj":"http://purl.org/sig/ont/fma/fma67906"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}

{"project":"LitCovid-PubTator","denotations":[{"id":"249","span":{"begin":37,"end":42},"obj":"Gene"},{"id":"250","span":{"begin":47,"end":60},"obj":"Gene"},{"id":"251","span":{"begin":79,"end":82},"obj":"Gene"},{"id":"252","span":{"begin":83,"end":87},"obj":"Gene"},{"id":"253","span":{"begin":194,"end":198},"obj":"Gene"},{"id":"273","span":{"begin":120,"end":128},"obj":"Species"},{"id":"274","span":{"begin":129,"end":137},"obj":"Species"},{"id":"283","span":{"begin":244,"end":249},"obj":"Gene"},{"id":"284","span":{"begin":150,"end":155},"obj":"Gene"},{"id":"298","span":{"begin":2,"end":13},"obj":"Disease"},{"id":"299","span":{"begin":93,"end":104},"obj":"Disease"}],"attributes":[{"id":"A249","pred":"tao:has_database_id","subj":"249","obj":"Gene:5972"},{"id":"A250","pred":"tao:has_database_id","subj":"250","obj":"Gene:183"},{"id":"A251","pred":"tao:has_database_id","subj":"251","obj":"Gene:59272"},{"id":"A252","pred":"tao:has_database_id","subj":"252","obj":"Gene:59272"},{"id":"A253","pred":"tao:has_database_id","subj":"253","obj":"Gene:59272"},{"id":"A273","pred":"tao:has_database_id","subj":"273","obj":"Tax:694009"},{"id":"A274","pred":"tao:has_database_id","subj":"274","obj":"Tax:9606"},{"id":"A283","pred":"tao:has_database_id","subj":"283","obj":"Gene:43740568"},{"id":"A284","pred":"tao:has_database_id","subj":"284","obj":"Gene:43740568"},{"id":"A298","pred":"tao:has_database_id","subj":"298","obj":"MESH:D007022"},{"id":"A299","pred":"tao:has_database_id","subj":"299","obj":"MESH:D013610"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T72","span":{"begin":2,"end":13},"obj":"Disease"},{"id":"T73","span":{"begin":120,"end":128},"obj":"Disease"},{"id":"T74","span":{"begin":120,"end":124},"obj":"Disease"}],"attributes":[{"id":"A72","pred":"mondo_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/MONDO_0005468"},{"id":"A73","pred":"mondo_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T42024","span":{"begin":164,"end":167},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T66445","span":{"begin":209,"end":217},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T1462","span":{"begin":250,"end":265},"obj":"http://purl.obolibrary.org/obo/GO_0043234"},{"id":"T66948","span":{"begin":324,"end":332},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T41","span":{"begin":47,"end":58},"obj":"Chemical"},{"id":"T42","span":{"begin":156,"end":163},"obj":"Chemical"},{"id":"T43","span":{"begin":250,"end":257},"obj":"Chemical"}],"attributes":[{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T14","span":{"begin":2,"end":13},"obj":"Phenotype"},{"id":"T15","span":{"begin":93,"end":104},"obj":"Phenotype"}],"attributes":[{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0002615"},{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0001649"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}

{"project":"2_test","denotations":[{"id":"32708755-16461478-20678672","span":{"begin":139,"end":141},"obj":"16461478"},{"id":"32708755-18490652-20678673","span":{"begin":270,"end":272},"obj":"18490652"},{"id":"32708755-15791205-20678674","span":{"begin":273,"end":275},"obj":"15791205"}],"text":"g hypotension (known to enhance both renin and angiotensin I, the substrate of ACE/ACE2) and tachycardia were common in SARS-CoV patients [23]. Since spike protein has been shown to not inhibit ACE2 enzymatic activity that is retained by sACE2-spike protein complex [16,17,24] and, in general, sACE2 maintains its enzymatic activity, we cannot consider its higher circul"}