PMC:7408073 / 60624-61143 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"2180","span":{"begin":473,"end":477},"obj":"Gene"},{"id":"2187","span":{"begin":121,"end":124},"obj":"Gene"},{"id":"2194","span":{"begin":83,"end":102},"obj":"Species"},{"id":"2197","span":{"begin":236,"end":241},"obj":"Chemical"},{"id":"2201","span":{"begin":49,"end":70},"obj":"Disease"},{"id":"2202","span":{"begin":311,"end":320},"obj":"Disease"},{"id":"2203","span":{"begin":497,"end":518},"obj":"Disease"}],"attributes":[{"id":"A2180","pred":"tao:has_database_id","subj":"2180","obj":"Gene:302668"},{"id":"A2187","pred":"tao:has_database_id","subj":"2187","obj":"Gene:100126231"},{"id":"A2194","pred":"tao:has_database_id","subj":"2194","obj":"Tax:10116"},{"id":"A2197","pred":"tao:has_database_id","subj":"2197","obj":"MESH:D014867"},{"id":"A2201","pred":"tao:has_database_id","subj":"2201","obj":"MESH:D009203"},{"id":"A2202","pred":"tao:has_database_id","subj":"2202","obj":"MESH:D006973"},{"id":"A2203","pred":"tao:has_database_id","subj":"2203","obj":"MESH:D009203"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T317","span":{"begin":49,"end":70},"obj":"Disease"},{"id":"T318","span":{"begin":497,"end":518},"obj":"Disease"}],"attributes":[{"id":"A317","pred":"mondo_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/MONDO_0005068"},{"id":"A318","pred":"mondo_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/MONDO_0005068"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T753","span":{"begin":13,"end":14},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T754","span":{"begin":78,"end":82},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T755","span":{"begin":78,"end":82},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T756","span":{"begin":143,"end":146},"obj":"http://purl.obolibrary.org/obo/CLO_0002096"},{"id":"T757","span":{"begin":200,"end":201},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T758","span":{"begin":302,"end":310},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T759","span":{"begin":302,"end":310},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"},{"id":"T760","span":{"begin":427,"end":429},"obj":"http://purl.obolibrary.org/obo/CLO_0001407"},{"id":"T761","span":{"begin":443,"end":444},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T6036","span":{"begin":78,"end":82},"obj":"Chemical"},{"id":"T60127","span":{"begin":143,"end":146},"obj":"Chemical"},{"id":"T121","span":{"begin":202,"end":210},"obj":"Chemical"},{"id":"T93537","span":{"begin":236,"end":241},"obj":"Chemical"},{"id":"T27633","span":{"begin":393,"end":398},"obj":"Chemical"}],"attributes":[{"id":"A12069","pred":"chebi_id","subj":"T6036","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A11577","pred":"chebi_id","subj":"T60127","obj":"http://purl.obolibrary.org/obo/CHEBI_15756"},{"id":"A13527","pred":"chebi_id","subj":"T121","obj":"http://purl.obolibrary.org/obo/CHEBI_75958"},{"id":"A53562","pred":"chebi_id","subj":"T93537","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A61990","pred":"chebi_id","subj":"T27633","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}

{"project":"LitCovid-sentences","denotations":[{"id":"T291","span":{"begin":0,"end":519},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T97","span":{"begin":49,"end":70},"obj":"Phenotype"},{"id":"T98","span":{"begin":497,"end":518},"obj":"Phenotype"}],"attributes":[{"id":"A97","pred":"hp_id","subj":"T97","obj":"http://purl.obolibrary.org/obo/HP_0001658"},{"id":"A98","pred":"hp_id","subj":"T98","obj":"http://purl.obolibrary.org/obo/HP_0001658"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}

{"project":"2_test","denotations":[{"id":"32708755-20797602-20678868","span":{"begin":427,"end":429},"obj":"20797602"}],"text":"Of interest, a report showed that on day 28 post-myocardial infarction, adult male Sprague-Dawley rats that had received MLN-4760 (also called C16) 25 mg/mL/day by daily intraperitoneal injection (as a solution of 42 mg/mL in distilled water) tended to have lower left ventricular pulse pressure, mean arterial pressures and left ventricular relaxation time constant-Tau compared to untreated group (see table 2 of the paper) [52], suggesting a possible protective role of ACE2 inhibition in post-myocardial infarction."}