PMC:7408073 / 55819-56019 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"2046","span":{"begin":40,"end":44},"obj":"Gene"},{"id":"2047","span":{"begin":93,"end":97},"obj":"Gene"},{"id":"2063","span":{"begin":34,"end":39},"obj":"Species"},{"id":"2064","span":{"begin":87,"end":92},"obj":"Species"},{"id":"2068","span":{"begin":0,"end":7},"obj":"Chemical"}],"attributes":[{"id":"A2046","pred":"tao:has_database_id","subj":"2046","obj":"Gene:59272"},{"id":"A2047","pred":"tao:has_database_id","subj":"2047","obj":"Gene:59272"},{"id":"A2063","pred":"tao:has_database_id","subj":"2063","obj":"Tax:9606"},{"id":"A2064","pred":"tao:has_database_id","subj":"2064","obj":"Tax:9606"},{"id":"A2068","pred":"tao:has_database_id","subj":"2068","obj":"MESH:C486469"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"MLN4760 is a potent and selective human ACE2 inhibitor (IC50 = 0.44 nM against soluble human ACE2) whose synthesis produces a racemic mixture of two diastereomers that showed 75:25 ratio for Isomer A:"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T679","span":{"begin":11,"end":12},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T680","span":{"begin":34,"end":39},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T681","span":{"begin":87,"end":92},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T682","span":{"begin":124,"end":125},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T683","span":{"begin":198,"end":199},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"MLN4760 is a potent and selective human ACE2 inhibitor (IC50 = 0.44 nM against soluble human ACE2) whose synthesis produces a racemic mixture of two diastereomers that showed 75:25 ratio for Isomer A:"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T26019","span":{"begin":40,"end":54},"obj":"Chemical"},{"id":"T54501","span":{"begin":45,"end":54},"obj":"Chemical"},{"id":"T75789","span":{"begin":126,"end":141},"obj":"Chemical"},{"id":"T7082","span":{"begin":134,"end":141},"obj":"Chemical"}],"attributes":[{"id":"A31811","pred":"chebi_id","subj":"T26019","obj":"http://purl.obolibrary.org/obo/CHEBI_147289"},{"id":"A68673","pred":"chebi_id","subj":"T54501","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A83384","pred":"chebi_id","subj":"T75789","obj":"http://purl.obolibrary.org/obo/CHEBI_60911"},{"id":"A87263","pred":"chebi_id","subj":"T7082","obj":"http://purl.obolibrary.org/obo/CHEBI_60004"}],"text":"MLN4760 is a potent and selective human ACE2 inhibitor (IC50 = 0.44 nM against soluble human ACE2) whose synthesis produces a racemic mixture of two diastereomers that showed 75:25 ratio for Isomer A:"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T119","span":{"begin":105,"end":114},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"MLN4760 is a potent and selective human ACE2 inhibitor (IC50 = 0.44 nM against soluble human ACE2) whose synthesis produces a racemic mixture of two diastereomers that showed 75:25 ratio for Isomer A:"}

{"project":"LitCovid-sentences","denotations":[{"id":"T270","span":{"begin":0,"end":200},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"MLN4760 is a potent and selective human ACE2 inhibitor (IC50 = 0.44 nM against soluble human ACE2) whose synthesis produces a racemic mixture of two diastereomers that showed 75:25 ratio for Isomer A:"}