PMC:7408073 / 55091-55347 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T374","span":{"begin":185,"end":193},"obj":"Body_part"}],"attributes":[{"id":"A374","pred":"fma_id","subj":"T374","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1987","span":{"begin":27,"end":31},"obj":"Gene"},{"id":"1988","span":{"begin":110,"end":114},"obj":"Gene"},{"id":"1989","span":{"begin":145,"end":149},"obj":"Gene"},{"id":"1990","span":{"begin":163,"end":167},"obj":"Gene"},{"id":"1991","span":{"begin":221,"end":225},"obj":"Gene"},{"id":"1995","span":{"begin":179,"end":184},"obj":"Gene"},{"id":"1996","span":{"begin":4,"end":9},"obj":"Gene"}],"attributes":[{"id":"A1987","pred":"tao:has_database_id","subj":"1987","obj":"Gene:59272"},{"id":"A1988","pred":"tao:has_database_id","subj":"1988","obj":"Gene:59272"},{"id":"A1989","pred":"tao:has_database_id","subj":"1989","obj":"Gene:59272"},{"id":"A1990","pred":"tao:has_database_id","subj":"1990","obj":"Gene:59272"},{"id":"A1991","pred":"tao:has_database_id","subj":"1991","obj":"Gene:59272"},{"id":"A1995","pred":"tao:has_database_id","subj":"1995","obj":"Gene:43740568"},{"id":"A1996","pred":"tao:has_database_id","subj":"1996","obj":"Gene:43740568"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T675","span":{"begin":66,"end":74},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T676","span":{"begin":236,"end":244},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T37661","span":{"begin":185,"end":193},"obj":"Chemical"}],"attributes":[{"id":"A62553","pred":"chebi_id","subj":"T37661","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T267","span":{"begin":0,"end":256},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24]."}

{"project":"2_test","denotations":[{"id":"32708755-18490652-20678847","span":{"begin":249,"end":251},"obj":"18490652"},{"id":"32708755-15791205-20678848","span":{"begin":252,"end":254},"obj":"15791205"}],"text":"The spike binding sites on ACE2 homodimer are localized above the membrane-distal peptidase subdomain of each ACE2 monomer, nevertheless neither ACE2 shedding nor ACE2 binding to spike proteins have been shown to inhibit ACE2 enzymatic activity [16,17,24]."}