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PMC:7408073 / 48938-53763 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T327 159-163 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T328 180-186 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T329 245-257 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T330 245-249 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T331 266-271 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T332 288-294 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T333 313-318 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T334 320-337 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T335 332-337 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T336 339-346 Body_part denotes neurons http://purl.org/sig/ont/fma/fma54527
T337 351-365 Body_part denotes cardiomyocytes http://purl.org/sig/ont/fma/fma14067
T338 629-644 Body_part denotes plasma to cells http://purl.org/sig/ont/fma/fma70574
T339 629-635 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T340 639-644 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T341 733-738 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T342 1462-1466 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T343 1478-1484 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T344 1730-1741 Body_part denotes neural cell http://purl.org/sig/ont/fma/fma70333
T345 1737-1741 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T346 1816-1822 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T347 1851-1858 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T348 1931-1941 Body_part denotes fatty acid http://purl.org/sig/ont/fma/fma82738
T349 1943-1946 Body_part denotes FFA http://purl.org/sig/ont/fma/fma82738
T350 2243-2246 Body_part denotes FFA http://purl.org/sig/ont/fma/fma82738
T351 2479-2485 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T352 2668-2674 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T353 2938-2945 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T354 3146-3152 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T355 3216-3222 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T356 3326-3330 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T357 3358-3364 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T358 3427-3433 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T359 3817-3822 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T360 4036-4042 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T361 4108-4113 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T362 4291-4307 Body_part denotes endothelial cell http://purl.org/sig/ont/fma/fma66772
T363 4303-4307 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T364 4363-4381 Body_part denotes pulmonary arteries http://purl.org/sig/ont/fma/fma66326
T365 4373-4381 Body_part denotes arteries http://purl.org/sig/ont/fma/fma63812
T366 4485-4493 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T367 4639-4643 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T368 4694-4698 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T111 733-738 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T112 1462-1466 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T113 3307-3310 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T114 3326-3330 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T115 3817-3822 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T116 4108-4113 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T117 4363-4381 Body_part denotes pulmonary arteries http://purl.obolibrary.org/obo/UBERON_0002012
T118 4639-4643 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T119 4694-4698 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1875 221-224 Gene denotes ZIP Gene:84619
1876 1431-1434 Gene denotes ZIP Gene:84619
1877 1590-1593 Gene denotes ZIP Gene:84619
1878 1823-1830 Gene denotes albumin Gene:213
1879 2329-2336 Gene denotes albumin Gene:213
1880 2912-2922 Gene denotes fibrinogen Gene:2244
1881 3365-3372 Gene denotes albumin Gene:213
1882 2719-2726 Gene denotes albumin Gene:213
1883 2629-2636 Gene denotes albumin Gene:213
1884 2267-2274 Gene denotes albumin Gene:213
1885 1994-2001 Gene denotes albumin Gene:213
1886 1244-1252 Species denotes patients Tax:9606
1887 3780-3787 Species denotes patient Tax:9606
1888 4816-4824 Species denotes patients Tax:9606
1889 41-46 Chemical denotes metal MESH:D008670
1890 202-206 Chemical denotes Zn2+
1891 1286-1290 Chemical denotes Zn2+
1892 1333-1337 Chemical denotes Fe2+
1893 1342-1346 Chemical denotes Cu2+
1894 1402-1407 Chemical denotes metal MESH:D008670
1895 1549-1553 Chemical denotes Fe2+
1896 1581-1585 Chemical denotes Zn2+
1897 1679-1689 Chemical denotes EDTA metal
1898 1868-1873 Chemical denotes metal MESH:D008670
1899 1926-1941 Chemical denotes free fatty acid MESH:D005230
1900 1943-1946 Chemical denotes FFA MESH:D005230
1901 2035-2040 Chemical denotes metal MESH:D008670
1902 2308-2314 Chemical denotes carbon MESH:D002244
1903 2359-2363 Chemical denotes Zn2+
1904 2758-2762 Chemical denotes Zn2+
1905 2847-2851 Chemical denotes Zn2+
1906 2938-2945 Chemical denotes heparin MESH:D006493
1907 3541-3546 Chemical denotes ZnCl2 MESH:C016837
1908 3547-3550 Chemical denotes ZnO MESH:D015034
1909 3551-3567 Chemical denotes hexachloroethane MESH:C010182
1910 733-750 Disease denotes blood coagulation MESH:D001778
1911 836-859 Disease denotes cardiovascular diseases MESH:D002318
1912 861-879 Disease denotes metabolic syndrome MESH:D024821
1913 881-893 Disease denotes inflammation MESH:D007249
1914 907-913 Disease denotes stress MESH:D000079225
1915 915-923 Disease denotes diabetes MESH:D003920
1916 928-938 Disease denotes thrombosis MESH:D013927
1917 1055-1074 Disease denotes Alzheimer’s disease MESH:D000544
1918 1079-1098 Disease denotes cardiac dysfunction MESH:D006331
1919 1198-1207 Disease denotes Alzheimer MESH:D000544
1920 1218-1243 Disease denotes neurodegenerative disease MESH:D019636
1921 1513-1521 Disease denotes COVID-19 MESH:C000657245
1922 1742-1747 Disease denotes death MESH:D003643
1923 1769-1795 Disease denotes neurodegenerative diseases MESH:D019636
1924 2400-2412 Disease denotes dyslipidemia MESH:D050171
1925 2512-2518 Disease denotes stress MESH:D000079225
1926 2821-2840 Disease denotes Alzheimer’s disease MESH:D000544
1927 3061-3071 Disease denotes thrombotic MESH:D013927
1928 3382-3385 Disease denotes IBD MESH:D015212
1929 3387-3391 Disease denotes ARDS MESH:D012128
1930 3396-3404 Disease denotes COVID-19 MESH:C000657245
1931 3496-3500 Disease denotes ARDS MESH:D012128
1932 3747-3751 Disease denotes ARDS MESH:D012128
1933 3846-3850 Disease denotes ARDS MESH:D012128
1934 3865-3870 Disease denotes death MESH:D003643
1935 3876-3894 Disease denotes multiorgan failure MESH:D009102
1936 3922-3937 Disease denotes hepatic failure MESH:D017093
1937 4149-4154 Disease denotes death MESH:D003643
1938 4166-4185 Disease denotes respiratory failure MESH:D012131
1939 4419-4447 Disease denotes acute pulmonary hypertension MESH:D006976
1940 4494-4502 Disease denotes fibrosis MESH:D005355
1941 4591-4599 Disease denotes coughing MESH:D003371
1942 4604-4611 Disease denotes dyspnea MESH:D004417
1943 4807-4815 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T283 836-859 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T284 861-879 Disease denotes metabolic syndrome http://purl.obolibrary.org/obo/MONDO_0004955
T285 881-893 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T286 915-923 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T287 928-938 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T288 1014-1021 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T289 1055-1074 Disease denotes Alzheimer’s disease http://purl.obolibrary.org/obo/MONDO_0004975
T290 1218-1243 Disease denotes neurodegenerative disease http://purl.obolibrary.org/obo/MONDO_0005559
T291 1513-1521 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T292 1769-1795 Disease denotes neurodegenerative diseases http://purl.obolibrary.org/obo/MONDO_0005559
T293 1943-1946 Disease denotes FFA http://purl.obolibrary.org/obo/MONDO_0016776
T294 2243-2246 Disease denotes FFA http://purl.obolibrary.org/obo/MONDO_0016776
T295 2400-2412 Disease denotes dyslipidemia http://purl.obolibrary.org/obo/MONDO_0002525
T296 2768-2775 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T297 2821-2840 Disease denotes Alzheimer’s disease http://purl.obolibrary.org/obo/MONDO_0004975
T298 3382-3385 Disease denotes IBD http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265
T300 3387-3391 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T301 3396-3404 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T302 3496-3500 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T303 3747-3751 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T304 3846-3850 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T305 3876-3894 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T306 4166-4185 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T307 4308-4314 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T308 4425-4447 Disease denotes pulmonary hypertension http://purl.obolibrary.org/obo/MONDO_0005149
T309 4435-4447 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T310 4807-4815 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T602 19-20 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T603 159-169 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T604 180-186 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T605 245-249 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T606 266-271 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T607 288-294 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T608 313-318 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T609 320-337 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T610 351-365 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiomyocytes
T611 591-601 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T612 629-644 http://purl.obolibrary.org/obo/CL_0000786 denotes plasma to cells
T613 733-738 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T614 733-738 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T615 761-771 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T616 777-778 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T617 977-980 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T618 1014-1034 http://purl.obolibrary.org/obo/PR_000036193 denotes amyloid beta-peptide
T619 1175-1178 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T620 1365-1366 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T621 1478-1484 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T622 1699-1702 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T623 1737-1741 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T624 1759-1765 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T625 1797-1800 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T626 1816-1822 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T627 1839-1840 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T628 2017-2018 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T629 2296-2299 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T630 2376-2377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T631 2479-2485 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T632 2523-2533 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T633 2668-2674 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T634 2709-2710 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T635 2768-2789 http://purl.obolibrary.org/obo/PR_000036193 denotes amyloid beta-peptides
T636 2852-2855 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T637 2946-2954 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T638 2978-2981 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T639 2992-2993 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T640 3146-3152 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T641 3216-3222 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T642 3289-3299 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T643 3358-3364 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T644 3427-3433 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T645 3778-3779 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T646 3955-3956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T647 4010-4011 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T648 4036-4042 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T649 4108-4113 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T650 4108-4113 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T651 4291-4307 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cell
T652 4363-4381 http://purl.obolibrary.org/obo/UBERON_0002012 denotes pulmonary arteries
T653 4363-4381 http://www.ebi.ac.uk/efo/EFO_0001399 denotes pulmonary arteries
T654 4639-4643 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T655 4639-4643 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T656 4694-4698 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T657 4694-4698 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T658 4708-4713 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T42913 111-115 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T61190 202-205 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T14672 405-409 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T35422 428-432 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T6498 522-526 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T46147 619-623 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T80373 756-760 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T99687 965-969 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T73526 1014-1026 Chemical denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T25126 1022-1026 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T81124 1027-1034 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T69400 1121-1129 Chemical denotes zinc ion http://purl.obolibrary.org/obo/CHEBI_27365
T43909 1121-1125 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T90698 1126-1129 Chemical denotes ion http://purl.obolibrary.org/obo/CHEBI_24870
T23 1286-1289 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T11305 1318-1324 Chemical denotes metals http://purl.obolibrary.org/obo/CHEBI_33521
T25 1408-1412 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T8552 1581-1584 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T27 1636-1640 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T46411 1679-1683 Chemical denotes EDTA http://purl.obolibrary.org/obo/CHEBI_42191|http://purl.obolibrary.org/obo/CHEBI_64755
T9001 1690-1698 Chemical denotes chelator http://purl.obolibrary.org/obo/CHEBI_38161
T72606 1851-1858 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34459 1874-1878 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T8109 1887-1891 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T36 1908-1917 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T35424 1931-1941 Chemical denotes fatty acid http://purl.obolibrary.org/obo/CHEBI_35366
T51103 1937-1941 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T4450 1943-1946 Chemical denotes FFA http://purl.obolibrary.org/obo/CHEBI_42638|http://purl.obolibrary.org/obo/CHEBI_35366
T26241 2024-2031 Chemical denotes carrier http://purl.obolibrary.org/obo/CHEBI_78059
T16974 2041-2045 Chemical denotes ions http://purl.obolibrary.org/obo/CHEBI_24870
T80700 2062-2071 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T93666 2107-2116 Chemical denotes molecules http://purl.obolibrary.org/obo/CHEBI_25367
T47509 2243-2246 Chemical denotes FFA http://purl.obolibrary.org/obo/CHEBI_42638|http://purl.obolibrary.org/obo/CHEBI_35366
T36449 2251-2255 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T66182 2308-2314 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T10714 2315-2320 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T87033 2359-2362 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T84664 2471-2475 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T4649 2611-2615 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T68380 2758-2761 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T39438 2768-2780 Chemical denotes amyloid beta http://purl.obolibrary.org/obo/CHEBI_64645
T95341 2776-2780 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T90891 2781-2789 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T79507 2847-2850 Chemical denotes Zn2 http://purl.obolibrary.org/obo/CHEBI_37256
T11769 2938-2945 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T88200 3237-3241 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T72355 3307-3310 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T765 3476-3480 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T83715 3541-3546 Chemical denotes ZnCl2 http://purl.obolibrary.org/obo/CHEBI_49976
T56869 3547-3550 Chemical denotes ZnO http://purl.obolibrary.org/obo/CHEBI_36560
T70147 3551-3567 Chemical denotes hexachloroethane http://purl.obolibrary.org/obo/CHEBI_39227
T4674 3823-3827 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T51227 4043-4047 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T103 136-145 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T104 136-145 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T105 721-731 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T106 733-750 http://purl.obolibrary.org/obo/GO_0007596 denotes blood coagulation
T107 739-750 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T108 761-771 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T109 881-893 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T110 1042-1051 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T111 1636-1647 http://purl.obolibrary.org/obo/GO_0071578 denotes zinc uptake
T112 1641-1647 http://purl.obolibrary.org/obo/GO_0098739 denotes uptake
T113 1641-1647 http://purl.obolibrary.org/obo/GO_0098657 denotes uptake
T114 1737-1747 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T115 1841-1850 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T116 2656-2662 http://purl.obolibrary.org/obo/GO_0140352 denotes efflux
T117 2656-2662 http://purl.obolibrary.org/obo/GO_0140115 denotes efflux
T118 2808-2817 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T234 0-179 Sentence denotes Zinc is considered a relatively nontoxic metal; however, several data report that excessive free extracellular zinc is toxic and induce apoptosis in different cell types [91,102].
T235 180-513 Sentence denotes Plasma excess of free Zn2+ is uptaken by ZIP transporters on the cell surface of each cells in contact with plasma (including immune cells, endothelial cells, neurons and cardiomyocytes), leading to increase of intracellular zinc that can modulate zinc associated cellular functions in both physiological and pathological conditions.
T236 514-944 Sentence denotes Indeed, zinc is an important mediator/messenger involved in several cellular activities and the shift of zinc from plasma to cells may be significant for both normal physiological processes including energy metabolism, blood coagulation, and zinc signalling, and a range of disease states, including neurodegenerative and cardiovascular diseases, metabolic syndrome, inflammation, endothelial stress, diabetes and thrombosis [91].
T237 945-1171 Sentence denotes For example, excess zinc intake has been shown to contribute to both amyloid beta-peptide plaque formation in Alzheimer’s disease and cardiac dysfunction, indicating that free zinc ion may be much more toxic than thought [91].
T238 1172-1448 Sentence denotes It has been reported that Alzheimer and other neurodegenerative disease patients show elevated levels not only of Zn2+ but also of other divalent metals such as Fe2+ and Cu2+ [112], suggesting a possible link between the increase metal ions and saturation of ZIP transporters.
T239 1449-1662 Sentence denotes On the other hand, increased plasma ferritin levels (such as in COVID-19 [2,3,6]) might reduce free Fe2+ and its “competition” with Zn2+ for ZIP transporters, finally increasing cellular zinc uptake and functions.
T240 1663-1802 Sentence denotes To this regard, EDTA metal chelator has been shown to protect from neural cell death and it was tested in neurodegenerative diseases [102].
T241 1803-1985 Sentence denotes Of interest, plasma albumin acts as a transport protein for both metal ions such as zinc and hydrophobic molecules such as free fatty acid (FFA) to allow their systemic distribution.
T242 1986-2167 Sentence denotes Indeed, albumin is well beyond a mere carrier of metal ions and hydrophobic molecules, and by binding of these different molecules mediates their crosstalk and bioavailability [91].
T243 2168-2280 Sentence denotes To this regard, one particularly intriguing allosteric link exists between FFA and zinc binding to albumin [91].
T244 2281-2486 Sentence denotes When FFAs with ten or more carbon atoms bind to albumin causes the release of Zn2+, suggesting a possible link between dyslipidemia and toxic effects mediated by consequent increase of free zinc in plasma.
T245 2487-2675 Sentence denotes For example, endothelial stress and activation and pro-inflammatory action of FFAs may be mediated by their effects on free zinc release from albumin and its consequent efflux from plasma.
T246 2676-2846 Sentence denotes Different studies have suggested a role of albumin to inhibit interaction of free Zn2+ with amyloid beta-peptides and combat plaque formation in Alzheimer’s disease [91].
T247 2847-2960 Sentence denotes Zn2+ has also been shown to promote clot stability by binding to fibrinogen and inhibiting heparin activity [91].
T248 2961-3082 Sentence denotes An evidence that has suggested a possible positive correlation between increased levels of FFAs and thrombotic risk [91].
T249 3083-3312 Sentence denotes In addition, physiological conditions associated with elevated plasma FFAs, such as physical exercise, can also produce an increased plasma level of free zinc and its downstream physiological events (e.g., activation of the RAS).
T250 3313-3481 Sentence denotes On the other hand, reduced concentrations of plasma albumin (such as IBD, ARDS and COVID-19) will induce elevated plasma levels of both free FFAs and bioavailable zinc.
T251 3482-3644 Sentence denotes Intriguingly, ARDS is induced after inhalation exposure to ZnCl2/ZnO/hexachloroethane, the main ingredients in smoke bombs used for crowd dispersal [100,101,102].
T252 3645-3762 Sentence denotes To this regard, soldiers that breathed smoke-bomb fumes have been shown to quickly or slowly develope ARDS [100,101].
T253 3763-3945 Sentence denotes Interestingly, a patient who had the highest level of serum zinc rapidly developed ARDS that leads to death from multiorgan failure (including respiratory and hepatic failure) [100].
T254 3946-4233 Sentence denotes Instead, a slow progressive clinical course was associated with a significant increase of plasma zinc concentration that negatively correlated with pulmonary and liver function [100], finally leading to death for severe respiratory failure three to five weeks after inhalation [100,101].
T255 4234-4334 Sentence denotes At autopsy diffuse microvascular obliteration and marked endothelial cell injury was apparent [101].
T256 4335-4527 Sentence denotes Widespread occlusion of the pulmonary arteries may contribute to the development of acute pulmonary hypertension and extensive interstitial and intra-alveolar fibrosis was also observed [101].
T257 4528-4740 Sentence denotes Other soldiers wearing gas masks, immediately developed severe coughing and dyspnea, and slowly improved their lung function (only twelve months after exposure their lung function tests were nearly normal) [101].
T258 4741-4825 Sentence denotes All clinical conditions that strongly resemble those described in COVID-19 patients.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T81 836-859 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T82 1055-1074 Phenotype denotes Alzheimer’s disease http://purl.obolibrary.org/obo/HP_0002511
T83 1218-1243 Phenotype denotes neurodegenerative disease http://purl.obolibrary.org/obo/HP_0002180
T84 1468-1493 Phenotype denotes increased plasma ferritin http://purl.obolibrary.org/obo/HP_0003281
T85 1769-1795 Phenotype denotes neurodegenerative diseases http://purl.obolibrary.org/obo/HP_0002180
T86 2400-2412 Phenotype denotes dyslipidemia http://purl.obolibrary.org/obo/HP_0003119
T87 2821-2840 Phenotype denotes Alzheimer’s disease http://purl.obolibrary.org/obo/HP_0002511
T88 3922-3937 Phenotype denotes hepatic failure http://purl.obolibrary.org/obo/HP_0001399
T89 4166-4185 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T90 4435-4447 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T91 4591-4599 Phenotype denotes coughing http://purl.obolibrary.org/obo/HP_0012735
T92 4604-4611 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094

2_test

Id Subject Object Predicate Lexical cue
32708755-30266430-20678824 171-173 30266430 denotes 91
32708755-20617034-20678825 174-177 20617034 denotes 102
32708755-30266430-20678826 940-942 30266430 denotes 91
32708755-30266430-20678827 1167-1169 30266430 denotes 91
32708755-32161940-20678828 1523-1524 32161940 denotes 2
32708755-32171076-20678829 1525-1526 32171076 denotes 3
32708755-32294485-20678830 1527-1528 32294485 denotes 6
32708755-20617034-20678831 1797-1800 20617034 denotes 102
32708755-30266430-20678832 2163-2165 30266430 denotes 91
32708755-30266430-20678833 2276-2278 30266430 denotes 91
32708755-30266430-20678834 2842-2844 30266430 denotes 91
32708755-30266430-20678835 2956-2958 30266430 denotes 91
32708755-30266430-20678836 3078-3080 30266430 denotes 91
32708755-28953660-20678837 3631-3634 28953660 denotes 100
32708755-20617034-20678838 3639-3642 20617034 denotes 102
32708755-28953660-20678839 3753-3756 28953660 denotes 100
32708755-28953660-20678840 3940-3943 28953660 denotes 100
32708755-28953660-20678841 4124-4127 28953660 denotes 100
32708755-28953660-20678842 4224-4227 28953660 denotes 100