PMC:7408073 / 4046-4403 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T2030","span":{"begin":35,"end":40},"obj":"Body_part"},{"id":"T47742","span":{"begin":86,"end":102},"obj":"Body_part"},{"id":"T6114","span":{"begin":97,"end":102},"obj":"Body_part"},{"id":"T36553","span":{"begin":116,"end":133},"obj":"Body_part"},{"id":"T93384","span":{"begin":128,"end":133},"obj":"Body_part"},{"id":"T78860","span":{"begin":203,"end":207},"obj":"Body_part"},{"id":"T18627","span":{"begin":265,"end":272},"obj":"Body_part"},{"id":"T66005","span":{"begin":309,"end":316},"obj":"Body_part"}],"attributes":[{"id":"A26041","pred":"fma_id","subj":"T2030","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A33879","pred":"fma_id","subj":"T47742","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A97935","pred":"fma_id","subj":"T6114","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A46870","pred":"fma_id","subj":"T36553","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A98191","pred":"fma_id","subj":"T93384","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A88498","pred":"fma_id","subj":"T78860","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A51983","pred":"fma_id","subj":"T18627","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A50982","pred":"fma_id","subj":"T66005","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T7","span":{"begin":203,"end":207},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-PubTator","denotations":[{"id":"228","span":{"begin":47,"end":51},"obj":"Gene"},{"id":"229","span":{"begin":304,"end":308},"obj":"Gene"},{"id":"263","span":{"begin":256,"end":261},"obj":"Gene"},{"id":"266","span":{"begin":226,"end":234},"obj":"Species"},{"id":"290","span":{"begin":284,"end":286},"obj":"Chemical"},{"id":"291","span":{"begin":203,"end":214},"obj":"Disease"}],"attributes":[{"id":"A228","pred":"tao:has_database_id","subj":"228","obj":"Gene:59272"},{"id":"A229","pred":"tao:has_database_id","subj":"229","obj":"Gene:70008"},{"id":"A263","pred":"tao:has_database_id","subj":"263","obj":"Gene:43740568"},{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"Tax:694009"},{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"MESH:D014316"},{"id":"A291","pred":"tao:has_database_id","subj":"291","obj":"MESH:D055370"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T54","span":{"begin":197,"end":214},"obj":"Disease"},{"id":"T56","span":{"begin":208,"end":214},"obj":"Disease"},{"id":"T57","span":{"begin":226,"end":234},"obj":"Disease"},{"id":"T58","span":{"begin":226,"end":230},"obj":"Disease"}],"attributes":[{"id":"A54","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A55","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0015796"},{"id":"A56","pred":"mondo_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A57","pred":"mondo_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A58","pred":"mondo_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T11956","span":{"begin":35,"end":40},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T59818","span":{"begin":79,"end":85},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T25048","span":{"begin":86,"end":96},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T45947","span":{"begin":97,"end":102},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T10170","span":{"begin":116,"end":133},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T36367","span":{"begin":162,"end":163},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T94559","span":{"begin":203,"end":207},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T18915","span":{"begin":203,"end":207},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T49004","span":{"begin":262,"end":264},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T42150","span":{"begin":328,"end":331},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T31","span":{"begin":265,"end":272},"obj":"Chemical"},{"id":"T32","span":{"begin":309,"end":316},"obj":"Chemical"}],"attributes":[{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-sentences","denotations":[{"id":"T23","span":{"begin":47,"end":240},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T13","span":{"begin":197,"end":214},"obj":"Phenotype"}],"attributes":[{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://www.orpha.net/ORDO/Orphanet_178320"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}

{"project":"2_test","denotations":[{"id":"32708755-32142651-20678655","span":{"begin":42,"end":44},"obj":"32142651"},{"id":"32708755-16007097-20678656","span":{"begin":236,"end":238},"obj":"16007097"}],"text":"cilitating viral entry into target cells [13]. ACE2 is abundantly expressed in airway epithelial cells and vascular endothelial cells, and it is believed to play a crucial role in the mechanism of acute lung injury induced by SARS-CoV [14]. The ability of spike-Fc protein treatment (3h) to downregulate ACE2 protein expression has been shown in an in vitro"}