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PMC:7408073 / 35164-35624 JSONTXT

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LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T77 31-34 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T78 64-67 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1367 129-133 Gene denotes ACE2 Gene:59272
1368 179-182 Gene denotes ACE Gene:59272
1369 220-224 Gene denotes MasR Gene:116511
1370 248-252 Gene denotes ACE2 Gene:59272
1371 254-257 Gene denotes ACE Gene:59272
1372 262-267 Gene denotes renin Gene:5972
1373 407-411 Gene denotes MasR Gene:116511
1374 169-174 Gene denotes renin Gene:5972
1375 314-323 Species denotes SARS-CoVs Tax:694009

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T229 314-318 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T412 19-23 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T413 144-152 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T414 193-201 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T415 278-288 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T416 384-385 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T310 31-34 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T311 46-56 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T312 64-67 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T164 0-35 Sentence denotes Inhibition of both arms of the RAS.
T165 36-233 Sentence denotes Among the inhibitors of the RAS pathways, different strategy can be pursued involving either ACE2 enzymatic activity or its upstream renin and ACE enzymatic activity or its downstream MasR pathway.
T166 234-460 Sentence denotes Inhibition of ACE2, ACE and renin enzymatic activities and their involvement in SARS-CoVs will be extensively discussed in the next sections, instead a brief description of MasR inhibition will be presented in the present Box.