PMC:7408073 / 29825-30108
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T197 | 19-26 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T198 | 165-169 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1078 | 165-170 | Gene | denotes | IL-1β | Gene:3552 |
| 1079 | 175-180 | Gene | denotes | TNF-α | Gene:7124 |
| 1080 | 252-256 | Gene | denotes | ACE2 | Gene:59272 |
| 1082 | 145-153 | Species | denotes | SARS-CoV | Tax:694009 |
| 1260 | 38-42 | Gene | denotes | ACE2 | Gene:59272 |
| 1276 | 13-18 | Gene | denotes | spike | Gene:43740568 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T202 | 145-153 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T203 | 145-149 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T367 | 63-73 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T368 | 243-251 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T255 | 19-26 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T256 | 165-167 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T53 | 190-199 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T141 | 0-283 | Sentence | denotes | Indeed, upon spike protein binding to ACE2, downstream pathway activation can sustain positive feedback loops at different levels (Figure 2):(1) SARS-CoV can induce IL-1β and TNF-α systemic secretion that can mediate viral-independent surface membrane ACE2 upregulation and shedding. |