PMC:7408073 / 29392-29653 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T196","span":{"begin":191,"end":202},"obj":"Body_part"}],"attributes":[{"id":"A196","pred":"fma_id","subj":"T196","obj":"http://purl.org/sig/ont/fma/fma66835"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T58","span":{"begin":203,"end":207},"obj":"Body_part"}],"attributes":[{"id":"A58","pred":"uberon_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/UBERON_0002415"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1252","span":{"begin":54,"end":59},"obj":"Gene"},{"id":"1253","span":{"begin":126,"end":132},"obj":"Gene"},{"id":"1254","span":{"begin":133,"end":137},"obj":"Gene"},{"id":"1255","span":{"begin":186,"end":190},"obj":"Gene"},{"id":"1256","span":{"begin":233,"end":239},"obj":"Gene"},{"id":"1257","span":{"begin":240,"end":244},"obj":"Gene"},{"id":"1279","span":{"begin":19,"end":37},"obj":"Disease"}],"attributes":[{"id":"A1252","pred":"tao:has_database_id","subj":"1252","obj":"Gene:7124"},{"id":"A1253","pred":"tao:has_database_id","subj":"1253","obj":"Gene:6868"},{"id":"A1254","pred":"tao:has_database_id","subj":"1254","obj":"Gene:6868"},{"id":"A1255","pred":"tao:has_database_id","subj":"1255","obj":"Gene:59272"},{"id":"A1256","pred":"tao:has_database_id","subj":"1256","obj":"Gene:6868"},{"id":"A1257","pred":"tao:has_database_id","subj":"1257","obj":"Gene:6868"},{"id":"A1279","pred":"tao:has_database_id","subj":"1279","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T197","span":{"begin":19,"end":37},"obj":"Disease"},{"id":"T198","span":{"begin":19,"end":23},"obj":"Disease"},{"id":"T199","span":{"begin":28,"end":37},"obj":"Disease"}],"attributes":[{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A198","pred":"mondo_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T364","span":{"begin":203,"end":207},"obj":"http://purl.obolibrary.org/obo/UBERON_0002415"},{"id":"T365","span":{"begin":245,"end":255},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T52","span":{"begin":60,"end":69},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T139","span":{"begin":0,"end":261},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}

{"project":"2_test","denotations":[{"id":"32708755-18490652-20678747","span":{"begin":257,"end":259},"obj":"18490652"}],"text":"Intriguingly, both SARS-CoV infection and concomitant TNF-α secretion were significantly attenuated not only by knock-down of ADAM17/TACE expression by siRNA but also by deletion of the ACE2 cytoplasmic tail which is responsible for ADAM17/TACE activation [17]."}