PMC:7408073 / 278-551 JSONTXT

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T4","span":{"begin":111,"end":114},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"ARS-CoV-2 in order to prevent positive feedback-loop mechanisms. Based purely on experimental studies in which RAS pathway inhibitors were administered in vivo to humans/rodents, a reasonable hypothesis of using inhibitors that block both ACE and ACE2 zinc metalloproteases"}

{"project":"LitCovid-PubTator","denotations":[{"id":"21","span":{"begin":239,"end":242},"obj":"Gene"},{"id":"22","span":{"begin":247,"end":251},"obj":"Gene"},{"id":"27","span":{"begin":163,"end":169},"obj":"Species"}],"attributes":[{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"Gene:59272"},{"id":"A22","pred":"tao:has_database_id","subj":"22","obj":"Gene:59272"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ARS-CoV-2 in order to prevent positive feedback-loop mechanisms. Based purely on experimental studies in which RAS pathway inhibitors were administered in vivo to humans/rodents, a reasonable hypothesis of using inhibitors that block both ACE and ACE2 zinc metalloproteases"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1177","span":{"begin":163,"end":169},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T48692","span":{"begin":179,"end":180},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"ARS-CoV-2 in order to prevent positive feedback-loop mechanisms. Based purely on experimental studies in which RAS pathway inhibitors were administered in vivo to humans/rodents, a reasonable hypothesis of using inhibitors that block both ACE and ACE2 zinc metalloproteases"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":111,"end":114},"obj":"Chemical"},{"id":"T5","span":{"begin":115,"end":133},"obj":"Chemical"},{"id":"T6","span":{"begin":123,"end":133},"obj":"Chemical"},{"id":"T7","span":{"begin":212,"end":222},"obj":"Chemical"},{"id":"T8","span":{"begin":252,"end":256},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_76932"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A9","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"}],"text":"ARS-CoV-2 in order to prevent positive feedback-loop mechanisms. Based purely on experimental studies in which RAS pathway inhibitors were administered in vivo to humans/rodents, a reasonable hypothesis of using inhibitors that block both ACE and ACE2 zinc metalloproteases"}