PMC:7408073 / 26130-26427
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T182","span":{"begin":288,"end":295},"obj":"Body_part"}],"attributes":[{"id":"A182","pred":"fma_id","subj":"T182","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"igure 1). Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein e"}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"1027","span":{"begin":21,"end":29},"obj":"Gene"},{"id":"1028","span":{"begin":71,"end":77},"obj":"Gene"},{"id":"1029","span":{"begin":87,"end":91},"obj":"Gene"},{"id":"1030","span":{"begin":176,"end":180},"obj":"Gene"},{"id":"1031","span":{"begin":229,"end":237},"obj":"Gene"},{"id":"1032","span":{"begin":259,"end":263},"obj":"Gene"},{"id":"1060","span":{"begin":151,"end":157},"obj":"Gene"}],"attributes":[{"id":"A1027","pred":"tao:has_database_id","subj":"1027","obj":"Gene:305843"},{"id":"A1028","pred":"tao:has_database_id","subj":"1028","obj":"Gene:24179"},{"id":"A1029","pred":"tao:has_database_id","subj":"1029","obj":"Gene:302668"},{"id":"A1030","pred":"tao:has_database_id","subj":"1030","obj":"Gene:302668"},{"id":"A1031","pred":"tao:has_database_id","subj":"1031","obj":"Gene:305843"},{"id":"A1032","pred":"tao:has_database_id","subj":"1032","obj":"Gene:302668"},{"id":"A1060","pred":"tao:has_database_id","subj":"1060","obj":"Gene:24179"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"igure 1). Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein e"}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T330","span":{"begin":122,"end":129},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T331","span":{"begin":279,"end":287},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"igure 1). Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein e"}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T219","span":{"begin":21,"end":24},"obj":"Chemical"},{"id":"T220","span":{"begin":43,"end":48},"obj":"Chemical"},{"id":"T221","span":{"begin":71,"end":74},"obj":"Chemical"},{"id":"T222","span":{"begin":75,"end":77},"obj":"Chemical"},{"id":"T223","span":{"begin":118,"end":121},"obj":"Chemical"},{"id":"T224","span":{"begin":122,"end":129},"obj":"Chemical"},{"id":"T225","span":{"begin":151,"end":154},"obj":"Chemical"},{"id":"T226","span":{"begin":155,"end":157},"obj":"Chemical"},{"id":"T227","span":{"begin":229,"end":232},"obj":"Chemical"},{"id":"T228","span":{"begin":288,"end":295},"obj":"Chemical"}],"attributes":[{"id":"A219","pred":"chebi_id","subj":"T219","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A220","pred":"chebi_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/CHEBI_35457"},{"id":"A221","pred":"chebi_id","subj":"T221","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A222","pred":"chebi_id","subj":"T222","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A223","pred":"chebi_id","subj":"T223","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A224","pred":"chebi_id","subj":"T224","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A225","pred":"chebi_id","subj":"T225","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A226","pred":"chebi_id","subj":"T226","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A227","pred":"chebi_id","subj":"T227","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A228","pred":"chebi_id","subj":"T228","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"igure 1). Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein e"}
LitCovid-PD-GO-BP
{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T47","span":{"begin":264,"end":277},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"igure 1). Therefore, Ang (1–7) (as well as ACEIs and ARBs), preventing Ang II-mediated ACE2 downregulation, shift the Ang peptide balance in favour of Ang II metabolisation by ACE2, which, in turn, leads to further production of Ang (1–7), finally sustaining ACE2 transcription, membrane protein e"}