PMC:7408073 / 24440-24752 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T170","span":{"begin":29,"end":38},"obj":"Body_part"},{"id":"T171","span":{"begin":206,"end":210},"obj":"Body_part"}],"attributes":[{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma12520"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}

{"project":"LitCovid-PubTator","denotations":[{"id":"823","span":{"begin":9,"end":14},"obj":"Gene"},{"id":"824","span":{"begin":50,"end":54},"obj":"Gene"},{"id":"825","span":{"begin":191,"end":195},"obj":"Gene"},{"id":"826","span":{"begin":196,"end":204},"obj":"Gene"},{"id":"827","span":{"begin":226,"end":231},"obj":"Gene"},{"id":"871","span":{"begin":303,"end":311},"obj":"Species"},{"id":"953","span":{"begin":129,"end":137},"obj":"Disease"},{"id":"954","span":{"begin":265,"end":290},"obj":"Disease"},{"id":"955","span":{"begin":294,"end":302},"obj":"Disease"}],"attributes":[{"id":"A823","pred":"tao:has_database_id","subj":"823","obj":"Gene:3586"},{"id":"A824","pred":"tao:has_database_id","subj":"824","obj":"Gene:59272"},{"id":"A825","pred":"tao:has_database_id","subj":"825","obj":"Gene:59272"},{"id":"A826","pred":"tao:has_database_id","subj":"826","obj":"Gene:284"},{"id":"A827","pred":"tao:has_database_id","subj":"827","obj":"Gene:3586"},{"id":"A871","pred":"tao:has_database_id","subj":"871","obj":"Tax:9606"},{"id":"A953","pred":"tao:has_database_id","subj":"953","obj":"MESH:C000657245"},{"id":"A955","pred":"tao:has_database_id","subj":"955","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T167","span":{"begin":129,"end":137},"obj":"Disease"},{"id":"T168","span":{"begin":294,"end":302},"obj":"Disease"}],"attributes":[{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T313","span":{"begin":211,"end":221},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T190","span":{"begin":9,"end":11},"obj":"Chemical"},{"id":"T192","span":{"begin":196,"end":199},"obj":"Chemical"},{"id":"T193","span":{"begin":226,"end":228},"obj":"Chemical"}],"attributes":[{"id":"A190","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A191","pred":"chebi_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A192","pred":"chebi_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A193","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A194","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}

{"project":"LitCovid-sentences","denotations":[{"id":"T116","span":{"begin":0,"end":312},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}

{"project":"2_test","denotations":[{"id":"32708755-32161940-20678730","span":{"begin":139,"end":140},"obj":"32161940"},{"id":"32708755-31986264-20678731","span":{"begin":141,"end":142},"obj":"31986264"},{"id":"32708755-32297671-20678732","span":{"begin":143,"end":144},"obj":"32297671"}],"text":"Of note, IL-10 is one of the cytokines downstream ACE2 pathway [25] and is significantly upregulated in the most severe forms of COVID-19 [2,8,9], indicating an important correlation between ACE2/Ang (1–7) axis activation and IL-10 upregulation which might lead to eosinopaenia/lymphopaenia in COVID-19 patients."}