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PMC:7408073 / 19373-19910 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T133 73-77 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T134 121-125 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T135 129-134 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T136 231-235 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
772 53-57 Gene denotes ACE2 Gene:70008
773 68-72 Gene denotes MasR Gene:116511
774 97-100 Gene denotes ACE Gene:70008
775 161-166 Gene denotes Ren-2 Gene:19702
776 219-224 Gene denotes Ren-2 Gene:19702
777 438-443 Gene denotes renin Gene:24715
778 486-489 Gene denotes ACE Gene:302668
779 493-497 Gene denotes ACE2 Gene:302668
838 58-66 Gene denotes Ang (1–7 Gene:11727
856 178-182 Species denotes rats Tax:10116
857 213-218 Species denotes mouse Tax:10090
858 288-292 Species denotes rats Tax:10116
859 359-363 Species denotes rats Tax:10116
872 167-177 Species denotes transgenic Tax:10090
873 328-333 Gene denotes renin Gene:5972
874 225-230 Gene denotes renin Gene:5972
883 101-107 Gene denotes Ang II Gene:24179
929 23-30 Disease denotes hypoxia MESH:D000860
930 138-160 Disease denotes pulmonary hypertensive MESH:D006976
931 346-358 Disease denotes hypertensive MESH:D006973
932 421-428 Disease denotes hypoxia MESH:D000860
933 518-536 Disease denotes hypoxic conditions MESH:D000071069

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T146 108-111 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T147 138-160 Disease denotes pulmonary hypertensive http://purl.obolibrary.org/obo/MONDO_0005149

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T229 39-49 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T230 129-134 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T231 213-218 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T232 231-235 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T233 334-342 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T128 58-61 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T129 101-104 Chemical denotes Ang http://purl.obolibrary.org/obo/CHEBI_48433
T130 105-107 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T28 409-428 http://purl.obolibrary.org/obo/GO_0001666 denotes response to hypoxia

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T96 0-537 Sentence denotes Interestingly, chronic hypoxia induced activation of ACE2/Ang (1–7)/MasR axis and suppression of ACE/Ang II/AT1 receptor axis in lungs of pulmonary hypertensive Ren-2 transgenic rats (constructed by inserting the mouse Ren-2 renin gene) but not in normotensive transgene-negative control rats [60], suggesting that the baseline renin activity in hypertensive rats may be crucial to determine the differential response to hypoxia and that renin inhibition might be useful to inhibit the ACE to ACE2 pathway shift under hypoxic conditions.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T35 23-30 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T36 421-428 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418

2_test

Id Subject Object Predicate Lexical cue
32708755-25194138-20678712 294-296 25194138 denotes 60