PMC:7408073 / 15550-15943 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T100","span":{"begin":305,"end":310},"obj":"Body_part"}],"attributes":[{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma9670"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T28","span":{"begin":305,"end":310},"obj":"Body_part"}],"attributes":[{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"740","span":{"begin":63,"end":67},"obj":"Gene"},{"id":"741","span":{"begin":206,"end":218},"obj":"Gene"},{"id":"742","span":{"begin":220,"end":224},"obj":"Gene"},{"id":"743","span":{"begin":253,"end":261},"obj":"Gene"},{"id":"839","span":{"begin":137,"end":145},"obj":"Gene"},{"id":"844","span":{"begin":152,"end":156},"obj":"Species"},{"id":"845","span":{"begin":357,"end":361},"obj":"Species"},{"id":"887","span":{"begin":56,"end":62},"obj":"Gene"},{"id":"896","span":{"begin":321,"end":340},"obj":"Disease"},{"id":"897","span":{"begin":345,"end":353},"obj":"Disease"}],"attributes":[{"id":"A740","pred":"tao:has_database_id","subj":"740","obj":"Gene:185"},{"id":"A741","pred":"tao:has_database_id","subj":"741","obj":"Gene:116511"},{"id":"A742","pred":"tao:has_database_id","subj":"742","obj":"Gene:116511"},{"id":"A743","pred":"tao:has_database_id","subj":"743","obj":"Gene:305843"},{"id":"A839","pred":"tao:has_database_id","subj":"839","obj":"Gene:11727"},{"id":"A844","pred":"tao:has_database_id","subj":"844","obj":"Tax:10090"},{"id":"A845","pred":"tao:has_database_id","subj":"845","obj":"Tax:10116"},{"id":"A887","pred":"tao:has_database_id","subj":"887","obj":"Gene:24179"},{"id":"A896","pred":"tao:has_database_id","subj":"896","obj":"MESH:D006332"},{"id":"A897","pred":"tao:has_database_id","subj":"897","obj":"MESH:D005355"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T127","span":{"begin":292,"end":319},"obj":"Disease"}],"attributes":[{"id":"A127","pred":"mondo_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T167","span":{"begin":76,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T168","span":{"begin":226,"end":236},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T169","span":{"begin":305,"end":310},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T170","span":{"begin":305,"end":310},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T171","span":{"begin":389,"end":391},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T103","span":{"begin":56,"end":59},"obj":"Chemical"},{"id":"T104","span":{"begin":60,"end":62},"obj":"Chemical"},{"id":"T105","span":{"begin":137,"end":140},"obj":"Chemical"},{"id":"T106","span":{"begin":253,"end":256},"obj":"Chemical"}],"attributes":[{"id":"A103","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A104","pred":"chebi_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A105","pred":"chebi_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A106","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T78","span":{"begin":103,"end":242},"obj":"Sentence"},{"id":"T79","span":{"begin":243,"end":393},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T18","span":{"begin":292,"end":319},"obj":"Phenotype"}],"attributes":[{"id":"A18","pred":"hp_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/HP_0032263"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}

{"project":"2_test","denotations":[{"id":"32708755-19404405-20678699","span":{"begin":238,"end":240},"obj":"19404405"}],"text":" that in some case resemble those produced by excessive Ang II/AT1R pathway activation (see Figure 1). For example, systemic infusion of Ang (1–7) into mice had renal proinflammatory properties mediated by Mas receptor (MasR) activation [47]. Moreover, Ang (1–7) infusion was associated with increases in blood pressure, cardiac hypertrophy and fibrosis in rats with subtotal nephrectomy [48]."}