PMC:7408073 / 113812-114149 JSONTXT

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T231","span":{"begin":52,"end":76},"obj":"Body_part"},{"id":"T232","span":{"begin":159,"end":162},"obj":"Body_part"},{"id":"T233","span":{"begin":215,"end":218},"obj":"Body_part"},{"id":"T234","span":{"begin":288,"end":291},"obj":"Body_part"}],"attributes":[{"id":"A231","pred":"uberon_id","subj":"T231","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"},{"id":"A232","pred":"uberon_id","subj":"T232","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"},{"id":"A233","pred":"uberon_id","subj":"T233","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"},{"id":"A234","pred":"uberon_id","subj":"T234","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"4705","span":{"begin":185,"end":188},"obj":"Gene"},{"id":"4706","span":{"begin":189,"end":193},"obj":"Gene"},{"id":"4707","span":{"begin":270,"end":280},"obj":"Species"},{"id":"4708","span":{"begin":52,"end":57},"obj":"Gene"},{"id":"4709","span":{"begin":262,"end":269},"obj":"Disease"}],"attributes":[{"id":"A4705","pred":"tao:has_database_id","subj":"4705","obj":"Gene:59272"},{"id":"A4706","pred":"tao:has_database_id","subj":"4706","obj":"Gene:59272"},{"id":"A4707","pred":"tao:has_database_id","subj":"4707","obj":"Tax:2697049"},{"id":"A4708","pred":"tao:has_database_id","subj":"4708","obj":"Gene:5972"},{"id":"A4709","pred":"tao:has_database_id","subj":"4709","obj":"MESH:D000860"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T609","span":{"begin":270,"end":278},"obj":"Disease"},{"id":"T610","span":{"begin":270,"end":274},"obj":"Disease"}],"attributes":[{"id":"A609","pred":"mondo_id","subj":"T609","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A610","pred":"mondo_id","subj":"T610","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T127","span":{"begin":40,"end":44},"obj":"http://www.ebi.ac.uk/efo/EFO_0001410"},{"id":"T128","span":{"begin":135,"end":145},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T77892","span":{"begin":58,"end":69},"obj":"Chemical"},{"id":"T95254","span":{"begin":159,"end":162},"obj":"Chemical"},{"id":"T71857","span":{"begin":215,"end":218},"obj":"Chemical"},{"id":"T21173","span":{"begin":219,"end":228},"obj":"Chemical"},{"id":"T63000","span":{"begin":288,"end":291},"obj":"Chemical"}],"attributes":[{"id":"A27931","pred":"chebi_id","subj":"T77892","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A68557","pred":"chebi_id","subj":"T95254","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A62337","pred":"chebi_id","subj":"T71857","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A46425","pred":"chebi_id","subj":"T21173","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A14023","pred":"chebi_id","subj":"T63000","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T12","span":{"begin":13,"end":23},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T574","span":{"begin":173,"end":337},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T174","span":{"begin":262,"end":269},"obj":"Phenotype"}],"attributes":[{"id":"A174","pred":"hp_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/HP_0012418"}],"text":"Interplay of regulation between the two arms of the renin-angiotensin system and pathophysiological consequences of excessive systemic activation of different RAS pathways. Reciprocal (ACE/ACE2) pathway inhibition, RAS inhibitor sites of action and influence of hypoxia/SARS-CoV-2 on the RAS are indicated. (for reference, see the text)."}