PMC:7408073 / 11052-11527 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7408073","sourcedb":"PMC","sourceid":"7408073","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7408073","text":"As already mentioned, circulating sACE2 protein shedding independent on virus contact has been also described either spontaneously when ACE2 transcription is upregulated or upon cytokine activation; it is therefore likely that in the bloodstreams ACE2 proteins are available to bind to both free S1 fragments and SARS-CoV-2 particles, finally leading to more and more S1-sACE2 and SARS-CoV-2-sACE2 complexes bearing enzymatic active sACE2 (see Figure later in the Section 4).","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T74","span":{"begin":40,"end":47},"obj":"Body_part"},{"id":"T75","span":{"begin":178,"end":186},"obj":"Body_part"},{"id":"T76","span":{"begin":252,"end":260},"obj":"Body_part"}],"attributes":[{"id":"A74","pred":"fma_id","subj":"T74","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A75","pred":"fma_id","subj":"T75","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A76","pred":"fma_id","subj":"T76","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"438","span":{"begin":136,"end":140},"obj":"Gene"},{"id":"439","span":{"begin":247,"end":251},"obj":"Gene"},{"id":"447","span":{"begin":313,"end":323},"obj":"Species"},{"id":"448","span":{"begin":381,"end":391},"obj":"Species"}],"attributes":[{"id":"A438","pred":"tao:has_database_id","subj":"438","obj":"Gene:59272"},{"id":"A439","pred":"tao:has_database_id","subj":"439","obj":"Gene:59272"},{"id":"A447","pred":"tao:has_database_id","subj":"447","obj":"Tax:2697049"},{"id":"A448","pred":"tao:has_database_id","subj":"448","obj":"Tax:2697049"},{"subj":"438","pred":"source","obj":"LitCovid-PubTator"},{"subj":"439","pred":"source","obj":"LitCovid-PubTator"},{"subj":"447","pred":"source","obj":"LitCovid-PubTator"},{"subj":"448","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T99","span":{"begin":313,"end":321},"obj":"Disease"},{"id":"T100","span":{"begin":313,"end":317},"obj":"Disease"},{"id":"T101","span":{"begin":381,"end":389},"obj":"Disease"},{"id":"T102","span":{"begin":381,"end":385},"obj":"Disease"}],"attributes":[{"id":"A99","pred":"mondo_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A100","pred":"mondo_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A101","pred":"mondo_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A102","pred":"mondo_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T102","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T15557","span":{"begin":72,"end":77},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T67356","span":{"begin":86,"end":89},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T824","span":{"begin":187,"end":197},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T96980","span":{"begin":296,"end":298},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T60119","span":{"begin":368,"end":370},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T36399","span":{"begin":426,"end":432},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"attributes":[{"subj":"T15557","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T67356","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T824","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T96980","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T60119","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T36399","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T69","span":{"begin":40,"end":47},"obj":"Chemical"},{"id":"T70","span":{"begin":252,"end":260},"obj":"Chemical"}],"attributes":[{"id":"A69","pred":"chebi_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T58005","span":{"begin":141,"end":154},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"attributes":[{"subj":"T58005","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T55","span":{"begin":0,"end":475},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T55","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#aa93ec","default":true},{"id":"LitCovid-PubTator","color":"#95ec93"},{"id":"LitCovid-PD-MONDO","color":"#ec93af"},{"id":"LitCovid-PD-CLO","color":"#93c9ec"},{"id":"LitCovid-PD-CHEBI","color":"#e3ec93"},{"id":"LitCovid-PD-GO-BP","color":"#db93ec"},{"id":"LitCovid-sentences","color":"#93ecc1"}]}]}}