PMC:7408073 / 102923-103319 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T18","span":{"begin":12,"end":17},"obj":"Body_part"},{"id":"T19","span":{"begin":108,"end":114},"obj":"Body_part"},{"id":"T20","span":{"begin":259,"end":263},"obj":"Body_part"}],"attributes":[{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma24728"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T210","span":{"begin":12,"end":17},"obj":"Body_part"},{"id":"T211","span":{"begin":259,"end":263},"obj":"Body_part"}],"attributes":[{"id":"A210","pred":"uberon_id","subj":"T210","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A211","pred":"uberon_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/UBERON_0001456"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}

{"project":"LitCovid-PubTator","denotations":[{"id":"3534","span":{"begin":170,"end":174},"obj":"Gene"},{"id":"3542","span":{"begin":102,"end":107},"obj":"Species"},{"id":"3543","span":{"begin":211,"end":219},"obj":"Species"},{"id":"3544","span":{"begin":378,"end":385},"obj":"Species"}],"attributes":[{"id":"A3534","pred":"tao:has_database_id","subj":"3534","obj":"Gene:59272"},{"id":"A3542","pred":"tao:has_database_id","subj":"3542","obj":"Tax:9606"},{"id":"A3543","pred":"tao:has_database_id","subj":"3543","obj":"Tax:9606"},{"id":"A3544","pred":"tao:has_database_id","subj":"3544","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T39","span":{"begin":12,"end":17},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T40","span":{"begin":12,"end":17},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T41","span":{"begin":43,"end":51},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T42","span":{"begin":90,"end":98},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T43","span":{"begin":102,"end":107},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T44","span":{"begin":108,"end":114},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T45","span":{"begin":153,"end":156},"obj":"http://purl.obolibrary.org/obo/CLO_0001046"},{"id":"T46","span":{"begin":175,"end":185},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T47","span":{"begin":240,"end":248},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T48","span":{"begin":259,"end":263},"obj":"http://purl.obolibrary.org/obo/UBERON_0001456"},{"id":"T49","span":{"begin":307,"end":308},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T55490","span":{"begin":142,"end":151},"obj":"Chemical"}],"attributes":[{"id":"A94508","pred":"chebi_id","subj":"T55490","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}

{"project":"LitCovid-sentences","denotations":[{"id":"T501","span":{"begin":0,"end":396},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}

{"project":"2_test","denotations":[{"id":"32708755-18223027-20679036","span":{"begin":153,"end":156},"obj":"18223027"}],"text":"Although in blood of normal subjects sACE2 activity is undetectable because its catalytic activity in human plasma is masked by an endogenous inhibitor [116] and chronic ACE2 activation may be deleterious, some patients might need of sACE2 activity to better face an acute pathological condition, therefore a careful monitoring of clinical parameters should be performed during patient treatment."}