PMC:7408073 / 100000-100961 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 124-139 Body_part denotes digestive tract http://purl.org/sig/ont/fma/fma317863
T2 168-173 Body_part denotes bowel http://purl.org/sig/ont/fma/fma7199
T3 629-634 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T4 685-693 Body_part denotes capsules http://purl.org/sig/ont/fma/fma85272
T5 829-837 Body_part denotes capsules http://purl.org/sig/ont/fma/fma85272

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T195 124-139 Body_part denotes digestive tract http://purl.obolibrary.org/obo/UBERON_0001555
T196 629-634 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3477 249-253 Gene denotes ACE2 Gene:59272
3478 25-28 Gene denotes MLN Gene:4295
3479 3-9 Species denotes humans Tax:9606
3480 155-181 Disease denotes Inflammatory bowel disease MESH:D015212
3481 183-204 Disease denotes gastritis and colitis MESH:D005756

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T555 140-153 Disease denotes inflammations http://purl.obolibrary.org/obo/MONDO_0021166
T556 155-181 Disease denotes Inflammatory bowel disease http://purl.obolibrary.org/obo/MONDO_0005265
T557 183-192 Disease denotes gastritis http://purl.obolibrary.org/obo/MONDO_0004966
T558 197-204 Disease denotes colitis http://purl.obolibrary.org/obo/MONDO_0005292

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 3-9 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T2 59-65 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T3 124-139 http://purl.obolibrary.org/obo/UBERON_0001555 denotes digestive tract
T4 258-259 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 277-284 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T6 629-634 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T7 629-634 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T8 811-817 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T9 851-852 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T3495 90-104 Chemical denotes pharmaceutical http://purl.obolibrary.org/obo/CHEBI_52217
T11 350-354 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T72202 818-822 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 140-153 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammations

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T484 86-254 Sentence denotes Its pharmaceutical indication was for digestive tract inflammations (Inflammatory bowel disease, gastritis and colitis) that are correlated with overexpression of ACE2.
T485 255-331 Sentence denotes In a Phase I clinical testing up 14 days dosing, ORE1001 was well tolerated.
T486 332-416 Sentence denotes Subjects received drug (dosing up to 2100 mg) with no side adverse effects reported.
T487 417-554 Sentence denotes In particular, 47 subjects received single-dose from 2.1 to 2100 mg and 24 subjects received 14 day multiple doses from 50 mg to 1800 mg.
T488 555-644 Sentence denotes All doses were well tolerated, with no significant side effects including blood pressure.
T489 645-802 Sentence denotes Pharmacokinetics of orally administered capsules was consistent with once-daily dosing. (http://oreholdings.com/wp-content/uploads/2013/06/09.10.09-425.pdf).
T490 803-961 Sentence denotes 300 mg (active drug) oral capsules were used in a Phase Ib/IIa clinical trial that was, however, abandoned. (https://clinicaltrials.gov/ct2/show/NCT01039597).

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T162 155-181 Phenotype denotes Inflammatory bowel disease http://purl.obolibrary.org/obo/HP_0002037
T163 183-192 Phenotype denotes gastritis http://purl.obolibrary.org/obo/HP_0005263
T164 197-204 Phenotype denotes colitis http://purl.obolibrary.org/obo/HP_0002583