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PMC:7405836 / 88296-90344 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T299 122-126 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T300 433-440 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T301 513-520 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T302 606-613 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T303 617-624 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T304 671-678 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T305 784-791 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T306 977-985 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T307 1314-1321 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T308 1478-1485 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T821 89-97 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T822 89-93 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T823 318-326 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T824 318-322 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T825 372-380 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T826 372-376 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T827 470-478 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T828 470-474 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T829 543-551 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T830 543-547 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T831 916-924 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T832 916-920 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T833 1088-1096 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T834 1088-1092 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T835 1103-1111 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T836 1103-1107 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T837 1193-1201 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T838 1193-1197 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T839 1221-1229 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T840 1221-1225 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T841 1272-1280 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T842 1335-1343 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T843 1335-1339 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T844 1359-1367 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T845 1359-1363 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T846 1561-1569 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T847 1561-1565 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T848 1633-1641 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T849 1703-1711 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T850 1703-1707 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T851 1739-1747 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T852 1739-1743 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T853 1752-1756 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T854 1831-1839 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T822 42-43 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T823 120-126 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T824 309-316 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T825 329-332 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T826 768-770 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T827 792-795 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T828 796-797 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T829 1462-1464 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T830 1522-1527 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T98001 127-134 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T36779 433-440 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T99525 513-520 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T1102 606-613 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T46765 617-624 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T88700 671-678 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T1050 784-791 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T39353 977-985 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T24940 1314-1321 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T83007 1478-1485 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T11468 1763-1765 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T615 0-220 Sentence denotes However, our previous attempts to develop a universal vaccine that is effective for both SARS-CoV and MERS-CoV based on T-cell epitope similarity pointed out the possibility of cross-reactivity among coronaviruses (172).
T616 221-317 Sentence denotes That can be made possible by selected potential vaccine targets that are common to both viruses.
T617 318-392 Sentence denotes SARS-CoV-2 has been reported to be closely related to SARS-CoV (173, 174).
T618 393-554 Sentence denotes Hence, knowledge and understanding of S protein-based vaccine development in SARS-CoV will help to identify potential S protein vaccine candidates in SARS-CoV-2.
T619 555-752 Sentence denotes Therefore, vaccine strategies based on the whole S protein, S protein subunits, or specific potential epitopes of S protein appear to be the most promising vaccine candidates against coronaviruses.
T620 753-850 Sentence denotes The RBD of the S1 subunit of S protein has a superior capacity to induce neutralizing antibodies.
T621 851-1031 Sentence denotes This property of the RBD can be utilized for designing potential SARS-CoV vaccines either by using RBD-containing recombinant proteins or recombinant vectors that encode RBD (175).
T622 1032-1232 Sentence denotes Hence, the superior genetic similarity existing between SARS-CoV-2 and SARS-CoV can be utilized to repurpose vaccines that have proven in vitro efficacy against SARS-CoV to be utilized for SARS-CoV-2.
T623 1233-1368 Sentence denotes The possibility of cross-protection in COVID-19 was evaluated by comparing the S protein sequences of SARS-CoV-2 with that of SARS-CoV.
T624 1369-1534 Sentence denotes The comparative analysis confirmed that the variable residues were found concentrated on the S1 subunit of S protein, an important vaccine target of the virus (150).
T625 1535-1657 Sentence denotes Hence, the possibility of SARS-CoV-specific neutralizing antibodies providing cross-protection to COVID-19 might be lower.
T626 1658-1840 Sentence denotes Further genetic analysis is required between SARS-CoV-2 and different strains of SARS-CoV and SARS-like (SL) CoVs to evaluate the possibility of repurposed vaccines against COVID-19.
T627 1841-2048 Sentence denotes This strategy will be helpful in the scenario of an outbreak, since much time can be saved, because preliminary evaluation, including in vitro studies, already would be completed for such vaccine candidates.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2467 1312-1313 Gene denotes S Gene:43740568
2468 89-97 Species denotes SARS-CoV Tax:694009
2469 102-110 Species denotes MERS-CoV Tax:1335626
2470 200-213 Species denotes coronaviruses Tax:11118
2471 318-328 Species denotes SARS-CoV-2 Tax:2697049
2472 372-380 Species denotes SARS-CoV Tax:694009
2473 470-478 Species denotes SARS-CoV Tax:694009
2474 543-553 Species denotes SARS-CoV-2 Tax:2697049
2475 738-751 Species denotes coronaviruses Tax:11118
2476 916-924 Species denotes SARS-CoV Tax:694009
2477 1088-1098 Species denotes SARS-CoV-2 Tax:2697049
2478 1103-1111 Species denotes SARS-CoV Tax:694009
2479 1193-1201 Species denotes SARS-CoV Tax:694009
2480 1221-1231 Species denotes SARS-CoV-2 Tax:2697049
2481 1335-1345 Species denotes SARS-CoV-2 Tax:2697049
2482 1359-1367 Species denotes SARS-CoV Tax:694009
2483 1561-1569 Species denotes SARS-CoV Tax:694009
2484 1703-1713 Species denotes SARS-CoV-2 Tax:2697049
2485 1739-1747 Species denotes SARS-CoV Tax:694009
2486 1767-1771 Species denotes CoVs Tax:11118
2487 1272-1280 Disease denotes COVID-19 MESH:C000657245
2488 1633-1641 Disease denotes COVID-19 MESH:C000657245
2489 1831-1839 Disease denotes COVID-19 MESH:C000657245