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PMC:7402624 / 54783-55351 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T452 166-171 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T453 289-294 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T454 321-323 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T455 360-364 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T456 394-398 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T457 420-422 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T458 436-441 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T459 492-502 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1764 160-163 Gene denotes CD4 Gene:920
1765 283-286 Gene denotes CD8 Gene:925
1766 314-319 Gene denotes T-bet Gene:30009
1767 354-357 Gene denotes CD8 Gene:925
1768 388-391 Gene denotes CD4 Gene:920
1778 83-91 Species denotes patients Tax:9606
1779 107-115 Species denotes patients Tax:9606
1789 74-82 Disease denotes COVID-19 MESH:C000657245
1790 515-524 Disease denotes infection MESH:D007239

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T373 74-82 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T374 321-323 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T375 420-422 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T376 515-524 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T829 128-138 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T830 160-163 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T831 164-171 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T832 217-227 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T833 260-269 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T834 283-286 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T835 287-294 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T836 299-300 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T837 354-357 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T838 358-364 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T839 388-391 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T840 392-398 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T841 434-441 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T842 537-538 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T843 557-567 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T60468 321-323 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T13552 340-348 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T70633 420-422 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T106 427-433 http://purl.obolibrary.org/obo/GO_0007613 denotes memory

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T318 0-568 Sentence denotes By deep immune profiling, we identified three immunotypes in hospitalized COVID-19 patients including: (1) patients with robust activation and proliferation of CD4 T cells, relative lack of cTfh, together with modest activation of TEMRA-like as well as highly activated or exhausted CD8 T cells and a signature of T-bet+ PB; (2) Tbetbright effector-like CD8 T cell responses, less robust CD4 T cell responses, and Ki67+ PB and memory B cells; and (3) an immunotype largely lacking detectable lymphocyte response to infection, suggesting a failure of immune activation.