PMC:7402624 / 47611-49159
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T413 | 99-103 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T414 | 230-235 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T415 | 321-326 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T416 | 507-512 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T417 | 595-600 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T418 | 677-682 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T419 | 746-751 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T420 | 824-828 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T421 | 997-1001 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T422 | 1073-1078 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T423 | 1116-1118 | Body_part | denotes | PB | http://purl.org/sig/ont/fma/fma84371 |
T424 | 1517-1520 | Body_part | denotes | IgM | http://purl.org/sig/ont/fma/fma62873 |
T425 | 1521-1529 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1609 | 224-227 | Gene | denotes | CD8 | Gene:925 |
1610 | 271-276 | Gene | denotes | T-bet | Gene:30009 |
1611 | 277-283 | Gene | denotes | CX3CR1 | Gene:1524 |
1612 | 496-500 | Gene | denotes | PD-1 | Gene:100513601 |
1613 | 501-505 | Gene | denotes | CD39 | Gene:397298 |
1614 | 589-592 | Gene | denotes | CD8 | Gene:925 |
1615 | 671-674 | Gene | denotes | CD4 | Gene:920 |
1616 | 740-743 | Gene | denotes | CD4 | Gene:920 |
1617 | 818-821 | Gene | denotes | CD4 | Gene:920 |
1618 | 860-864 | Gene | denotes | CD95 | Gene:355 |
1619 | 991-994 | Gene | denotes | CD4 | Gene:920 |
1620 | 1103-1108 | Gene | denotes | T-bet | Gene:30009 |
1621 | 1109-1114 | Gene | denotes | CD138 | Gene:6382 |
1622 | 1186-1190 | Gene | denotes | Tbet | Gene:30009 |
1623 | 1191-1196 | Gene | denotes | CD138 | Gene:6382 |
1624 | 137-145 | Species | denotes | patients | Tax:9606 |
1625 | 245-252 | Species | denotes | Cluster | Tax:100569 |
1626 | 450-457 | Species | denotes | Cluster | Tax:100569 |
1627 | 692-699 | Species | denotes | Cluster | Tax:100569 |
1628 | 874-881 | Species | denotes | Cluster | Tax:100569 |
1629 | 1092-1099 | Species | denotes | Cluster | Tax:100569 |
1630 | 1120-1127 | Species | denotes | Cluster | Tax:100569 |
1631 | 1198-1205 | Species | denotes | Cluster | Tax:100569 |
1632 | 1042-1046 | Chemical | denotes | cTfh | |
1633 | 128-136 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T336 | 128-136 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T337 | 1116-1118 | Disease | denotes | PB | http://purl.obolibrary.org/obo/MONDO_0019035 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T753 | 99-109 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T754 | 224-227 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
T755 | 228-235 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T756 | 253-255 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T757 | 321-326 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T758 | 471-480 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
T759 | 507-512 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T760 | 589-592 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
T761 | 593-600 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T762 | 671-674 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T763 | 675-682 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T764 | 715-724 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
T765 | 740-743 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T766 | 744-751 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T767 | 799-800 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T768 | 808-817 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
T769 | 818-821 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T770 | 822-828 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T771 | 991-994 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T772 | 995-1001 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T773 | 1071-1078 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
T774 | 1419-1421 | http://purl.obolibrary.org/obo/CLO_0008935 | denotes | S9 |
T775 | 1423-1424 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T322 | 307-315 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
T323 | 496-498 | Chemical | denotes | PD | http://purl.obolibrary.org/obo/CHEBI_74756 |
T324 | 558-566 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
T325 | 1116-1118 | Chemical | denotes | PB | http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T275 | 0-57 | Sentence | denotes | We next took advantage of the FlowSOM clustering in Figs. |
T276 | 58-209 | Sentence | denotes | 2 to 4 that identified individual immune cell types most perturbed in COVID-19 patients and linked these FlowSOM clusters to UMAP Components (Fig. 6H). |
T277 | 210-428 | Sentence | denotes | For non-naïve CD8 T cells, FlowSOM Cluster 11 that contained T-bet+CX3CR1+ but non-proliferating effector-like cells was positively correlated with UMAP Component 2 and negatively correlated with Component 1 (Fig. 6H). |
T278 | 429-666 | Sentence | denotes | In contrast, FlowSOM Cluster 14 contained activated, proliferating PD-1+CD39+ cells that might reflect either recently generated effector or possibly exhausted CD8 T cells (50) and was strongly associated with UMAP Component 1 (Fig. 6H). |
T279 | 667-934 | Sentence | denotes | For CD4 T cells, FlowSOM Cluster 14, containing activated, proliferating CD4 T cells, was captured by both UMAP Components, whereas a second activated CD4 T cell population that also expressed CD95 (FlowSOM Cluster 13) was only captured by UMAP Component 1 (Fig. 6H). |
T280 | 935-1057 | Sentence | denotes | In addition, Component 1 was negatively correlated with CD4 T cell FlowSOM Clusters 2 and 3 that contained cTfh (Fig. 6H). |
T281 | 1058-1261 | Sentence | denotes | Finally, for B cells, the FlowSOM Cluster of T-bet+CD138+ PB (Cluster 5) was positively correlated with Component 1 whereas the Tbet-CD138+ Cluster 3 was negatively correlated with Component 1 (Fig. 6H). |
T282 | 1262-1430 | Sentence | denotes | Locations in the UMAP immune landscape were dynamic, changing from D0 to D7 for both Component 1 and Component 2 consistent with the data in Fig. 5 and fig. S9, A to F. |
T283 | 1431-1548 | Sentence | denotes | The most dynamic changes in Component 1 were associated with the largest increases in IgM antibody levels (fig. S9G). |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32669297-26485519-135105217 | 602-604 | 26485519 | denotes | 50 |