PMC:7402624 / 36503-36942 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T337","span":{"begin":90,"end":100},"obj":"Body_part"},{"id":"T338","span":{"begin":223,"end":227},"obj":"Body_part"},{"id":"T339","span":{"begin":233,"end":237},"obj":"Body_part"},{"id":"T340","span":{"begin":257,"end":269},"obj":"Body_part"},{"id":"T341","span":{"begin":300,"end":303},"obj":"Body_part"},{"id":"T342","span":{"begin":373,"end":378},"obj":"Body_part"}],"attributes":[{"id":"A337","pred":"fma_id","subj":"T337","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A338","pred":"fma_id","subj":"T338","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A339","pred":"fma_id","subj":"T339","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A340","pred":"fma_id","subj":"T340","obj":"http://purl.org/sig/ont/fma/fma84371"},{"id":"A341","pred":"fma_id","subj":"T341","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A342","pred":"fma_id","subj":"T342","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Given this apparent stability between D0 and D7, we next investigated temporal changes in lymphocyte subpopulations of interest. Although there were no obvious temporal changes in major phenotypically defined CD4 and CD8 T cell or B cell subsets, including plasmablasts (Fig. 5D), the frequencies of HLA-DR+CD38+ and KI67+ non-naïve CD4 (Fig. 5B) and KI67+ non-naïve CD8 T cells were statistically increased at D7 compared to D0 (Fig. 5C)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1313","span":{"begin":209,"end":212},"obj":"Gene"},{"id":"1314","span":{"begin":217,"end":220},"obj":"Gene"},{"id":"1315","span":{"begin":307,"end":311},"obj":"Gene"},{"id":"1316","span":{"begin":333,"end":336},"obj":"Gene"},{"id":"1317","span":{"begin":367,"end":370},"obj":"Gene"}],"attributes":[{"id":"A1313","pred":"tao:has_database_id","subj":"1313","obj":"Gene:920"},{"id":"A1314","pred":"tao:has_database_id","subj":"1314","obj":"Gene:925"},{"id":"A1315","pred":"tao:has_database_id","subj":"1315","obj":"Gene:952"},{"id":"A1316","pred":"tao:has_database_id","subj":"1316","obj":"Gene:920"},{"id":"A1317","pred":"tao:has_database_id","subj":"1317","obj":"Gene:925"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Given this apparent stability between D0 and D7, we next investigated temporal changes in lymphocyte subpopulations of interest. Although there were no obvious temporal changes in major phenotypically defined CD4 and CD8 T cell or B cell subsets, including plasmablasts (Fig. 5D), the frequencies of HLA-DR+CD38+ and KI67+ non-naïve CD4 (Fig. 5B) and KI67+ non-naïve CD8 T cells were statistically increased at D7 compared to D0 (Fig. 5C)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T614","span":{"begin":209,"end":212},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T615","span":{"begin":217,"end":220},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T616","span":{"begin":221,"end":227},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T617","span":{"begin":231,"end":237},"obj":"http://purl.obolibrary.org/obo/CL_0000236"},{"id":"T618","span":{"begin":307,"end":311},"obj":"http://purl.obolibrary.org/obo/PR_000001408"},{"id":"T619","span":{"begin":333,"end":336},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T620","span":{"begin":367,"end":370},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T621","span":{"begin":371,"end":378},"obj":"http://purl.obolibrary.org/obo/CL_0000084"}],"text":"Given this apparent stability between D0 and D7, we next investigated temporal changes in lymphocyte subpopulations of interest. Although there were no obvious temporal changes in major phenotypically defined CD4 and CD8 T cell or B cell subsets, including plasmablasts (Fig. 5D), the frequencies of HLA-DR+CD38+ and KI67+ non-naïve CD4 (Fig. 5B) and KI67+ non-naïve CD8 T cells were statistically increased at D7 compared to D0 (Fig. 5C)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T264","span":{"begin":304,"end":306},"obj":"Chemical"},{"id":"T265","span":{"begin":343,"end":345},"obj":"Chemical"}],"attributes":[{"id":"A264","pred":"chebi_id","subj":"T264","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A265","pred":"chebi_id","subj":"T265","obj":"http://purl.obolibrary.org/obo/CHEBI_27560"}],"text":"Given this apparent stability between D0 and D7, we next investigated temporal changes in lymphocyte subpopulations of interest. Although there were no obvious temporal changes in major phenotypically defined CD4 and CD8 T cell or B cell subsets, including plasmablasts (Fig. 5D), the frequencies of HLA-DR+CD38+ and KI67+ non-naïve CD4 (Fig. 5B) and KI67+ non-naïve CD8 T cells were statistically increased at D7 compared to D0 (Fig. 5C)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T211","span":{"begin":0,"end":128},"obj":"Sentence"},{"id":"T212","span":{"begin":129,"end":439},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Given this apparent stability between D0 and D7, we next investigated temporal changes in lymphocyte subpopulations of interest. Although there were no obvious temporal changes in major phenotypically defined CD4 and CD8 T cell or B cell subsets, including plasmablasts (Fig. 5D), the frequencies of HLA-DR+CD38+ and KI67+ non-naïve CD4 (Fig. 5B) and KI67+ non-naïve CD8 T cells were statistically increased at D7 compared to D0 (Fig. 5C)."}