PMC:7402624 / 21674-23040
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T162 | 73-77 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T163 | 112-116 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T164 | 164-169 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T165 | 269-274 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T166 | 296-301 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T167 | 325-330 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T168 | 394-397 | Body_part | denotes | HLA | http://purl.org/sig/ont/fma/fma84795 |
T169 | 401-412 | Body_part | denotes | CD38+ cells | http://purl.org/sig/ont/fma/fma0326121 |
T170 | 407-412 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T171 | 506-509 | Body_part | denotes | HLA | http://purl.org/sig/ont/fma/fma84795 |
T172 | 513-524 | Body_part | denotes | CD38+ cells | http://purl.org/sig/ont/fma/fma0326121 |
T173 | 519-524 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T174 | 567-572 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T175 | 670-675 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T176 | 717-722 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T177 | 825-832 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T178 | 885-898 | Body_part | denotes | cell clusters | http://purl.org/sig/ont/fma/fma62807 |
T179 | 885-889 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T180 | 1042-1047 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T10 | 885-898 | Body_part | denotes | cell clusters | http://purl.obolibrary.org/obo/UBERON_0034922 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
773 | 67-70 | Gene | denotes | CD4 | Gene:920 |
774 | 106-109 | Gene | denotes | CD4 | Gene:920 |
775 | 290-293 | Gene | denotes | CD4 | Gene:920 |
776 | 319-322 | Gene | denotes | CD8 | Gene:925 |
777 | 401-405 | Gene | denotes | CD38 | Gene:952 |
778 | 513-517 | Gene | denotes | CD38 | Gene:952 |
779 | 540-543 | Gene | denotes | CD4 | Gene:920 |
780 | 561-564 | Gene | denotes | CD8 | Gene:925 |
781 | 664-667 | Gene | denotes | CD4 | Gene:920 |
782 | 711-714 | Gene | denotes | CD4 | Gene:920 |
783 | 879-882 | Gene | denotes | CD4 | Gene:920 |
784 | 1036-1039 | Gene | denotes | CD4 | Gene:920 |
785 | 365-373 | Species | denotes | patients | Tax:9606 |
786 | 607-615 | Species | denotes | patients | Tax:9606 |
787 | 749-757 | Species | denotes | patients | Tax:9606 |
788 | 1225-1232 | Species | denotes | patient | Tax:9606 |
789 | 1081-1088 | Species | denotes | cluster | Tax:100569 |
790 | 217-219 | Disease | denotes | HD | MESH:D006816 |
791 | 356-364 | Disease | denotes | COVID-19 | MESH:C000657245 |
792 | 460-462 | Disease | denotes | HD | MESH:D006816 |
793 | 598-606 | Disease | denotes | COVID-19 | MESH:C000657245 |
794 | 728-730 | Disease | denotes | HD | MESH:D006816 |
795 | 740-748 | Disease | denotes | COVID-19 | MESH:C000657245 |
796 | 1173-1175 | Disease | denotes | HD | MESH:D006816 |
797 | 1216-1224 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T155 | 217-219 | Disease | denotes | HD | http://purl.obolibrary.org/obo/MONDO_0007739 |
T156 | 356-364 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T157 | 460-462 | Disease | denotes | HD | http://purl.obolibrary.org/obo/MONDO_0007739 |
T158 | 598-606 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T159 | 728-730 | Disease | denotes | HD | http://purl.obolibrary.org/obo/MONDO_0007739 |
T160 | 732-734 | Disease | denotes | RD | http://purl.obolibrary.org/obo/MONDO_0009973 |
T161 | 740-748 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T162 | 1173-1175 | Disease | denotes | HD | http://purl.obolibrary.org/obo/MONDO_0007739 |
T163 | 1202-1204 | Disease | denotes | RD | http://purl.obolibrary.org/obo/MONDO_0009973 |
T164 | 1216-1224 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T165 | 1295-1297 | Disease | denotes | BH | http://purl.obolibrary.org/obo/MONDO_0010873 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T391 | 1-2 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T392 | 67-70 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T393 | 71-77 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T394 | 88-89 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T395 | 106-109 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T396 | 110-116 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T397 | 164-169 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T398 | 269-274 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T399 | 284-301 | http://purl.obolibrary.org/obo/CL_0000895 | denotes | naïve CD4 T cells |
T400 | 319-322 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
T401 | 323-330 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T402 | 401-405 | http://purl.obolibrary.org/obo/PR_000001408 | denotes | CD38 |
T403 | 407-412 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T404 | 513-517 | http://purl.obolibrary.org/obo/PR_000001408 | denotes | CD38 |
T405 | 519-524 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T406 | 540-543 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T407 | 561-564 | http://purl.obolibrary.org/obo/CLO_0053438 | denotes | CD8 |
T408 | 565-572 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T409 | 658-675 | http://purl.obolibrary.org/obo/CL_0000895 | denotes | naïve CD4 T cells |
T410 | 705-722 | http://purl.obolibrary.org/obo/CL_0000895 | denotes | naïve CD4 T cells |
T411 | 732-734 | http://purl.obolibrary.org/obo/CLO_0008770 | denotes | RD |
T412 | 873-889 | http://purl.obolibrary.org/obo/CL_0000895 | denotes | naïve CD4 T cell |
T413 | 1030-1047 | http://purl.obolibrary.org/obo/CL_0000895 | denotes | naïve CD4 T cells |
T414 | 1112-1113 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T415 | 1202-1204 | http://purl.obolibrary.org/obo/CLO_0008770 | denotes | RD |
T416 | 1285-1289 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T116 | 217-219 | Chemical | denotes | HD | http://purl.obolibrary.org/obo/CHEBI_73925 |
T117 | 398-400 | Chemical | denotes | DR | http://purl.obolibrary.org/obo/CHEBI_73445 |
T118 | 460-462 | Chemical | denotes | HD | http://purl.obolibrary.org/obo/CHEBI_73925 |
T119 | 510-512 | Chemical | denotes | DR | http://purl.obolibrary.org/obo/CHEBI_73445 |
T120 | 728-730 | Chemical | denotes | HD | http://purl.obolibrary.org/obo/CHEBI_73925 |
T121 | 732-734 | Chemical | denotes | RD | http://purl.obolibrary.org/obo/CHEBI_73812 |
T122 | 825-832 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T123 | 1166-1171 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
T124 | 1173-1175 | Chemical | denotes | HD | http://purl.obolibrary.org/obo/CHEBI_73925 |
T125 | 1195-1200 | Chemical | denotes | donor | http://purl.obolibrary.org/obo/CHEBI_17891 |
T126 | 1202-1204 | Chemical | denotes | RD | http://purl.obolibrary.org/obo/CHEBI_73812 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T135 | 0-221 | Sentence | denotes | (A) Representative flow cytometry plots of the gating strategy for CD4 T cell subsets. (B) Frequencies of CD4 T cell subsets as indicated. (C) Frequencies of KI67+ cells; green line at upper decile of healthy donors (HD). |
T136 | 222-464 | Sentence | denotes | Representative flow cytometry plots. (D) KI67+ cells from non-naïve CD4 T cells versus non-naïve CD8 T cells, Spearman correlation of COVID-19 patients. (E) Frequencies of HLA-DR+CD38+ cells; green line at upper decile of healthy donors (HD). |
T137 | 465-1089 | Sentence | denotes | Representative flow cytometry plots. (F) HLA-DR+CD38+ cells from non-naïve CD4 versus non-naïve CD8 T cells, Spearman correlation of COVID-19 patients. (G) (Top) Global viSNE projection of non-naïve CD4 T cells for all subjects pooled, non-naïve CD4 T cells from HD, RD, and COVID-19 patients concatenated and overlaid. (Bottom) viSNE projections of indicated protein expression. (H) viSNE projection of non-naïve CD4 T cell clusters identified by FlowSOM clustering. (I) Mean fluorescence intensity (MFI) as indicated, column-scaled z-score. (J) Percentage of non-naïve CD4 T cells from each cohort in each FlowSOM cluster. |
T138 | 1090-1239 | Sentence | denotes | Boxes represent IQR. (B, C, E, J) Each dot represents an individual healthy donor (HD; green), recovered donor (RD; blue), or COVID-19 patient (red). |
T139 | 1240-1366 | Sentence | denotes | Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. |