PMC:7402624 / 10799-11255 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T53","span":{"begin":21,"end":26},"obj":"Body_part"},{"id":"T54","span":{"begin":63,"end":68},"obj":"Body_part"},{"id":"T55","span":{"begin":87,"end":92},"obj":"Body_part"},{"id":"T56","span":{"begin":232,"end":236},"obj":"Body_part"},{"id":"T57","span":{"begin":358,"end":363},"obj":"Body_part"},{"id":"T58","span":{"begin":409,"end":414},"obj":"Body_part"}],"attributes":[{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Examining only CD3 T cells revealed preferential loss of CD8 T cells compared to CD4 T cells (Fig. 1, F and G, and fig. S1D); this pattern was reflected in absolute numbers estimated from the clinical data, where both CD4 and CD8 T cell counts in COVID-19 patients were lower than the clinical reference range, though the effect was more prominent for CD8 T cells (49/61 subjects below normal) than for CD4 T cells (38/61 subjects below normal) (fig. S1E)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"298","span":{"begin":81,"end":84},"obj":"Gene"},{"id":"299","span":{"begin":218,"end":221},"obj":"Gene"},{"id":"300","span":{"begin":226,"end":229},"obj":"Gene"},{"id":"301","span":{"begin":352,"end":355},"obj":"Gene"},{"id":"302","span":{"begin":403,"end":406},"obj":"Gene"},{"id":"304","span":{"begin":57,"end":60},"obj":"Gene"},{"id":"308","span":{"begin":256,"end":264},"obj":"Species"},{"id":"315","span":{"begin":247,"end":255},"obj":"Disease"}],"attributes":[{"id":"A298","pred":"tao:has_database_id","subj":"298","obj":"Gene:920"},{"id":"A299","pred":"tao:has_database_id","subj":"299","obj":"Gene:920"},{"id":"A300","pred":"tao:has_database_id","subj":"300","obj":"Gene:925"},{"id":"A301","pred":"tao:has_database_id","subj":"301","obj":"Gene:925"},{"id":"A302","pred":"tao:has_database_id","subj":"302","obj":"Gene:920"},{"id":"A304","pred":"tao:has_database_id","subj":"304","obj":"Gene:925"},{"id":"A308","pred":"tao:has_database_id","subj":"308","obj":"Tax:9606"},{"id":"A315","pred":"tao:has_database_id","subj":"315","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Examining only CD3 T cells revealed preferential loss of CD8 T cells compared to CD4 T cells (Fig. 1, F and G, and fig. S1D); this pattern was reflected in absolute numbers estimated from the clinical data, where both CD4 and CD8 T cell counts in COVID-19 patients were lower than the clinical reference range, though the effect was more prominent for CD8 T cells (49/61 subjects below normal) than for CD4 T cells (38/61 subjects below normal) (fig. S1E)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T83","span":{"begin":247,"end":255},"obj":"Disease"}],"attributes":[{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Examining only CD3 T cells revealed preferential loss of CD8 T cells compared to CD4 T cells (Fig. 1, F and G, and fig. S1D); this pattern was reflected in absolute numbers estimated from the clinical data, where both CD4 and CD8 T cell counts in COVID-19 patients were lower than the clinical reference range, though the effect was more prominent for CD8 T cells (49/61 subjects below normal) than for CD4 T cells (38/61 subjects below normal) (fig. S1E)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T115","span":{"begin":15,"end":18},"obj":"http://purl.obolibrary.org/obo/CLO_0052882"},{"id":"T116","span":{"begin":15,"end":18},"obj":"http://purl.obolibrary.org/obo/CLO_0053434"},{"id":"T117","span":{"begin":19,"end":26},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T118","span":{"begin":57,"end":60},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T119","span":{"begin":61,"end":68},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T120","span":{"begin":81,"end":84},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T121","span":{"begin":85,"end":92},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T122","span":{"begin":218,"end":221},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T123","span":{"begin":226,"end":229},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T124","span":{"begin":230,"end":236},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T125","span":{"begin":352,"end":355},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T126","span":{"begin":356,"end":363},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T127","span":{"begin":403,"end":406},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T128","span":{"begin":407,"end":414},"obj":"http://purl.obolibrary.org/obo/CL_0000084"}],"text":"Examining only CD3 T cells revealed preferential loss of CD8 T cells compared to CD4 T cells (Fig. 1, F and G, and fig. S1D); this pattern was reflected in absolute numbers estimated from the clinical data, where both CD4 and CD8 T cell counts in COVID-19 patients were lower than the clinical reference range, though the effect was more prominent for CD8 T cells (49/61 subjects below normal) than for CD4 T cells (38/61 subjects below normal) (fig. S1E)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T74","span":{"begin":0,"end":456},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Examining only CD3 T cells revealed preferential loss of CD8 T cells compared to CD4 T cells (Fig. 1, F and G, and fig. S1D); this pattern was reflected in absolute numbers estimated from the clinical data, where both CD4 and CD8 T cell counts in COVID-19 patients were lower than the clinical reference range, though the effect was more prominent for CD8 T cells (49/61 subjects below normal) than for CD4 T cells (38/61 subjects below normal) (fig. S1E)."}