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PMC:7402624 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 420-424 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T2 431-435 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T3 502-506 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T4 562-573 Body_part denotes plasmablast http://purl.org/sig/ont/fma/fma84371
T5 615-620 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T6 652-662 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T7 1863-1868 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T8 1975-1987 Body_part denotes compartments http://purl.org/sig/ont/fma/fma76577
T9 2025-2030 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T10 2159-2163 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T11 2200-2204 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 2242-2246 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T13 2439-2442 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T14 2459-2464 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T15 2472-2477 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T16 2531-2549 Body_part denotes regulatory T cells http://purl.org/sig/ont/fma/fma84070
T17 2544-2549 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T18 2565-2570 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T19 2581-2585 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T20 2666-2671 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T21 2769-2773 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T22 2833-2837 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T23 3215-3227 Body_part denotes plasmablasts http://purl.org/sig/ont/fma/fma84371
T24 3229-3231 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T25 3361-3364 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T26 3484-3487 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T27 3504-3507 Body_part denotes IgA http://purl.org/sig/ont/fma/fma62874
T28 3710-3716 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T29 4829-4833 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T30 5068-5073 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T31 5236-5241 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T32 6340-6345 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T33 6402-6412 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T34 7383-7389 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T35 8197-8204 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T36 8403-8411 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T37 8664-8680 Body_part denotes white blood cell http://purl.org/sig/ont/fma/fma62852
T38 8676-8680 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T39 8725-8734 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T40 9031-9039 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T41 9041-9051 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T42 9057-9065 Body_part denotes basophil http://purl.org/sig/ont/fma/fma62862
T43 10020-10029 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T44 10121-10155 Body_part denotes peripheral blood mononuclear cells http://purl.org/sig/ont/fma/fma86713
T45 10150-10155 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T46 10274-10284 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T47 10300-10304 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T48 10316-10320 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T49 10483-10488 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T50 10586-10590 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T51 10617-10628 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T52 10723-10727 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T53 10820-10825 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54 10862-10867 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T55 10886-10891 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 11031-11035 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T57 11157-11162 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T58 11208-11213 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T59 11400-11405 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T60 11445-11455 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T61 11600-11605 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T62 11648-11653 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T63 11679-11683 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T64 11813-11817 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T65 11971-11981 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T66 12041-12045 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T67 12162-12172 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T68 12749-12754 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T69 12772-12776 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T70 12857-12869 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T71 12857-12861 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T72 13099-13104 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T73 13122-13126 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T74 13263-13268 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T75 13362-13367 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T76 13499-13503 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T77 13604-13608 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T78 13694-13698 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T79 13706-13715 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T80 13864-13868 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T81 13903-13907 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T82 13964-13969 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T83 14004-14007 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T84 14011-14022 Body_part denotes CD38+ cells http://purl.org/sig/ont/fma/fma0326121
T85 14017-14022 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T86 14151-14156 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T87 14198-14203 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T88 14340-14347 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T89 14400-14413 Body_part denotes cell clusters http://purl.org/sig/ont/fma/fma62807
T90 14400-14404 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T91 14557-14562 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T92 14958-14963 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T93 15025-15028 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T94 15093-15096 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T95 15122-15127 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T96 15223-15228 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T97 15304-15309 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T98 15372-15376 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T99 15530-15535 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T100 15580-15583 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T101 15667-15671 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T102 15748-15751 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T103 15762-15767 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T104 15827-15832 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T105 15871-15874 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T106 15885-15890 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T107 15934-15937 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T108 15963-15968 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 16182-16186 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T110 16367-16372 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T111 16430-16434 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T112 16508-16511 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T113 16522-16527 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T114 16603-16607 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T115 16750-16754 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T116 16773-16778 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T117 16985-16990 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T118 17072-17075 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T119 17135-17140 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T120 17179-17182 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T121 17359-17364 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T122 17685-17689 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T123 17774-17779 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T124 18008-18011 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T125 18056-18061 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T126 18312-18316 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T127 18416-18421 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T128 18509-18513 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T129 18548-18552 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T130 18601-18605 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T131 18637-18642 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T132 19028-19043 Body_part denotes germinal center http://purl.org/sig/ont/fma/fma55224
T133 19119-19124 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T134 19565-19568 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T135 19589-19594 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T136 19707-19711 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T137 19775-19778 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T138 19783-19788 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T139 20101-20104 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T140 20127-20132 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T141 20188-20193 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T142 20255-20260 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T143 20276-20279 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T144 20380-20385 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T145 20430-20435 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T146 20522-20526 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T147 20636-20641 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T148 20763-20768 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T149 20787-20792 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T150 20873-20878 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T151 20897-20902 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T152 20937-20940 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T153 20961-20965 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T154 21081-21085 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T155 21158-21162 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T156 21246-21250 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T157 21301-21305 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T158 21491-21495 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T159 21528-21531 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T160 21580-21584 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T161 21660-21664 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T162 21747-21751 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T163 21786-21790 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T164 21838-21843 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T165 21943-21948 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T166 21970-21975 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T167 21999-22004 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T168 22068-22071 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T169 22075-22086 Body_part denotes CD38+ cells http://purl.org/sig/ont/fma/fma0326121
T170 22081-22086 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T171 22180-22183 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T172 22187-22198 Body_part denotes CD38+ cells http://purl.org/sig/ont/fma/fma0326121
T173 22193-22198 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T174 22241-22246 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T175 22344-22349 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 22391-22396 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T177 22499-22506 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T178 22559-22572 Body_part denotes cell clusters http://purl.org/sig/ont/fma/fma62807
T179 22559-22563 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T180 22716-22721 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T181 23069-23073 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T182 23184-23188 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T183 23373-23376 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T184 23435-23440 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T185 23480-23484 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T186 23697-23700 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T187 23803-23808 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T188 23921-23926 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T189 24108-24113 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T190 24334-24344 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T191 24345-24354 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T192 24484-24488 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T193 24548-24554 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T194 24729-24734 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T195 24773-24776 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T196 24793-24798 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T197 24871-24877 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T198 25081-25091 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T199 25123-25134 Body_part denotes eosinophils http://purl.org/sig/ont/fma/fma62861
T200 25136-25143 Body_part denotes eotaxin http://purl.org/sig/ont/fma/fma241992
T201 25160-25165 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T202 25507-25514 Body_part denotes eotaxin http://purl.org/sig/ont/fma/fma241992
T203 25660-25666 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T204 25726-25731 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T205 25883-25888 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T206 26059-26064 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T207 26305-26314 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T208 26319-26329 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T209 26360-26370 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T210 26436-26448 Body_part denotes plasmablasts http://purl.org/sig/ont/fma/fma84371
T211 26479-26483 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T212 26494-26498 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T213 26569-26573 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T214 26669-26672 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T215 26704-26707 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T216 26724-26729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T217 26800-26803 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T218 26807-26812 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T219 26828-26830 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T220 26895-26897 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T221 26932-26937 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T222 27033-27035 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T223 27125-27127 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T224 27219-27223 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T225 27437-27439 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T226 27566-27570 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T227 27647-27652 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T228 27715-27720 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T229 27749-27753 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T230 27927-27929 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T231 27993-27997 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T232 28127-28131 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T233 28159-28170 Body_part denotes plasmablast http://purl.org/sig/ont/fma/fma84371
T234 28195-28199 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T235 28256-28258 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T236 28261-28265 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T237 28334-28336 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T238 28439-28444 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T239 28531-28535 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T240 28579-28584 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T241 28628-28630 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T242 28684-28686 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T243 28706-28709 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T244 28788-28791 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T245 28800-28803 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T246 28844-28849 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T247 28882-28886 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T248 28981-28988 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T249 29114-29118 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T250 29246-29251 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T251 29330-29343 Body_part denotes cell clusters http://purl.org/sig/ont/fma/fma62807
T252 29330-29334 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T253 29443-29448 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T254 29878-29880 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T255 29925-29930 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T256 29998-30000 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T257 30212-30214 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T258 30283-30285 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T259 30424-30426 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T260 30446-30449 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T261 30469-30474 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T262 30522-30526 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T263 30607-30611 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T264 30720-30727 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T265 30736-30739 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T266 30748-30751 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T267 30759-30767 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T268 30798-30800 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T269 30860-30868 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T270 30973-30975 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T271 30993-31001 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T272 31044-31046 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T273 31124-31131 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T274 31225-31228 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T275 31233-31236 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T276 31395-31400 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T277 31498-31500 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T278 31587-31589 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T279 31667-31672 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T280 31755-31759 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T281 31884-31888 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T282 31934-31937 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T283 31952-31957 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T284 32005-32007 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T285 32170-32172 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T286 32238-32254 Body_part denotes germinal centers http://purl.org/sig/ont/fma/fma55224
T287 32375-32379 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T288 32511-32514 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T289 32762-32766 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T290 32995-33011 Body_part denotes cell compartment http://purl.org/sig/ont/fma/fma223408
T291 32995-32999 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T292 33134-33137 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T293 33203-33206 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T294 33291-33296 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T295 33298-33301 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T296 33331-33334 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T297 33537-33542 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T298 33737-33742 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T299 33805-33807 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T300 33926-33931 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T301 34001-34003 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T302 34091-34103 Body_part denotes cell Cluster http://purl.org/sig/ont/fma/fma62807
T303 34091-34095 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T304 34156-34160 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T305 34261-34263 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T306 34287-34291 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T307 34326-34330 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T308 34407-34423 Body_part denotes cell compartment http://purl.org/sig/ont/fma/fma223408
T309 34407-34411 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T310 34517-34521 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T311 34606-34610 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T312 34687-34691 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T313 34730-34734 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T314 34928-34932 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T315 34940-34944 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T316 34952-34956 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T317 35198-35202 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T318 35210-35214 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T319 35222-35226 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T320 35321-35338 Body_part denotes cells, the region http://purl.org/sig/ont/fma/fma85545
T321 35321-35326 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T322 35351-35354 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T323 35381-35384 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T324 35395-35399 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T325 35535-35539 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T326 35546-35550 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T327 35721-35726 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T328 35744-35749 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T329 35757-35762 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T330 35793-35798 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T331 35891-35894 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T332 35910-35915 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T333 35931-35934 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T334 35950-35955 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T335 36283-36286 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T336 36302-36307 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T337 36593-36603 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T338 36726-36730 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T339 36736-36740 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T340 36760-36772 Body_part denotes plasmablasts http://purl.org/sig/ont/fma/fma84371
T341 36803-36806 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T342 36876-36881 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T343 37398-37402 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T344 37531-37534 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T345 37560-37565 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T346 37612-37617 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T347 37696-37701 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T348 37795-37799 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T349 37953-37958 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T350 38083-38087 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T351 38160-38163 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T352 38387-38391 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T353 38500-38505 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T354 38698-38701 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T355 38762-38764 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T356 38802-38807 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T357 38885-38889 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T358 38895-38899 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T359 39134-39138 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T360 39224-39228 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T361 39485-39490 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T362 39492-39495 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T363 39638-39642 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T364 39709-39712 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T365 39724-39729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T366 39791-39794 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T367 39810-39814 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T368 39992-39994 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T369 40043-40048 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T370 40115-40123 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T371 40474-40476 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T372 40552-40554 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T373 40635-40638 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T374 40649-40654 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T375 40831-40834 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T376 40845-40850 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T377 41011-41013 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T378 41069-41073 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T379 41180-41184 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T380 41343-41347 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T381 41795-41799 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T382 41941-41946 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T383 41979-41984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T384 42112-42116 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T385 42123-42127 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T386 42228-42231 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T387 42247-42252 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T388 42279-42282 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T389 42298-42303 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T390 43657-43664 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T391 44476-44480 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T392 44777-44781 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T393 44827-44831 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T394 44839-44843 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T395 44850-44854 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T396 45062-45067 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T397 45092-45096 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T398 45351-45355 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T399 45839-45843 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T400 45928-45932 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T401 46717-46722 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T402 46749-46754 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T403 46766-46768 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T404 46832-46836 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T405 46944-46946 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T406 47023-47028 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T407 47040-47042 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T408 47077-47080 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T409 47114-47119 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T410 47323-47328 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T411 47402-47407 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T412 47492-47497 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T413 47710-47714 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T414 47841-47846 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T415 47932-47937 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T416 48118-48123 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T417 48206-48211 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T418 48288-48293 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T419 48357-48362 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T420 48435-48439 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T421 48608-48612 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T422 48684-48689 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T423 48727-48729 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T424 49128-49131 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T425 49132-49140 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T426 49445-49450 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T427 49483-49489 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T428 49705-49713 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T429 49961-49971 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T430 50822-50827 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T431 50901-50906 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T432 50918-50920 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T433 50998-51003 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T434 51037-51041 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T435 51094-51099 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T436 51238-51242 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T437 51400-51404 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T438 52230-52235 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T439 52236-52244 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T440 52542-52546 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T441 52718-52722 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T442 52802-52819 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T443 52830-52837 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T444 52986-52990 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T445 53133-53139 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T446 53278-53286 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T447 53998-54002 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T448 54434-54438 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T449 54452-54456 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T450 54490-54492 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T451 54679-54683 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T452 54949-54954 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T453 55072-55077 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T454 55104-55106 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T455 55143-55147 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T456 55177-55181 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T457 55203-55205 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T458 55219-55224 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T459 55275-55285 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T460 55390-55394 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T461 55450-55454 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T462 55874-55876 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T463 55905-55907 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T464 56007-56012 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T465 56013-56015 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T466 56058-56063 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T467 56152-56154 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T468 56227-56231 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T469 56272-56276 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T470 56291-56295 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T471 56344-56349 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T472 56412-56422 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T473 56503-56506 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T474 56518-56523 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T475 56557-56561 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T476 56770-56772 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T477 57063-57065 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T478 57133-57137 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T479 57349-57354 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T480 57433-57438 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T481 57602-57615 Body_part denotes cell clusters http://purl.org/sig/ont/fma/fma62807
T482 57602-57606 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T483 57686-57689 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T484 57708-57712 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T485 57911-57915 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T486 57955-57957 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T487 57972-57977 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T488 58044-58048 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T489 58064-58066 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T490 58334-58342 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T491 58426-58431 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T492 58432-58441 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T493 58468-58473 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T494 58492-58501 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T495 58506-58516 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T496 58554-58567 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T497 58562-58567 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T498 58723-58727 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T499 59417-59421 Body_part denotes back http://purl.org/sig/ont/fma/fma25056
T500 59686-59690 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T501 59763-59768 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T502 59780-59782 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T503 59904-59909 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T504 59930-59934 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T505 59964-59966 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T506 59980-59985 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T507 60059-60069 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T508 60264-60268 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T509 60387-60391 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T510 61248-61251 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T511 61341-61344 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T512 62144-62149 Body_part denotes mouth http://purl.org/sig/ont/fma/fma49184
T513 62274-62279 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T514 62578-62583 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T515 62852-62857 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T516 63487-63492 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T517 63519-63526 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T518 63591-63597 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T519 63635-63640 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T520 64080-64088 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T521 64240-64248 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T522 64540-64549 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T523 64833-64841 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T524 65422-65431 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T525 66124-66129 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T526 66441-66447 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T527 66649-66657 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T528 66744-66751 Body_part denotes Eotaxin http://purl.org/sig/ont/fma/fma241992
T529 66764-66767 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T530 66772-66775 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T531 66854-66858 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T532 66872-66876 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T533 67972-67977 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T534 68437-68441 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T535 70839-70844 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T536 71239-71244 Body_part denotes Joint http://purl.org/sig/ont/fma/fma7490
T537 71839-71844 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T538 71862-71867 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T539 71889-71894 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T540 71979-71984 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T541 72073-72078 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T542 72148-72151 Body_part denotes IgD http://purl.org/sig/ont/fma/fma62876
T543 72238-72241 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T544 72295-72300 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T545 72436-72439 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T546 72527-72531 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T547 72562-72565 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T548 72719-72724 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T549 72731-72736 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T550 72783-72787 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T551 72867-72871 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T552 73187-73195 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T553 73648-73652 Body_part denotes back http://purl.org/sig/ont/fma/fma25056
T554 75384-75386 Body_part denotes PB http://purl.org/sig/ont/fma/fma84371
T555 75397-75402 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T556 75434-75439 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T557 75471-75476 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T558 75478-75481 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T559 75515-75520 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T560 75522-75525 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T561 75559-75564 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T562 75648-75653 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T563 77152-77155 Body_part denotes MBP http://purl.org/sig/ont/fma/fma242151
T564 77484-77490 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T565 77504-77512 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T566 77828-77831 Body_part denotes MBP http://purl.org/sig/ont/fma/fma242151
T567 78545-78553 Body_part denotes Pancreas http://purl.org/sig/ont/fma/fma7198
T568 78655-78659 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T569 78741-78746 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T570 78823-78828 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 2472-2477 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T2 5068-5073 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 5236-5241 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T4 7383-7389 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T5 8670-8675 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T6 10132-10137 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T7 14400-14413 Body_part denotes cell clusters http://purl.obolibrary.org/obo/UBERON_0034922
T8 16773-16778 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T9 19028-19043 Body_part denotes germinal center http://purl.obolibrary.org/obo/UBERON_0010754
T10 22559-22572 Body_part denotes cell clusters http://purl.obolibrary.org/obo/UBERON_0034922
T11 24729-24734 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T12 24793-24798 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T13 29330-29343 Body_part denotes cell clusters http://purl.obolibrary.org/obo/UBERON_0034922
T14 29925-29930 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T15 32238-32254 Body_part denotes germinal centers http://purl.obolibrary.org/obo/UBERON_0010754
T16 34091-34103 Body_part denotes cell Cluster http://purl.obolibrary.org/obo/UBERON_0034922
T17 41615-41620 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T18 42513-42518 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T19 43324-43329 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T20 49445-49450 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T21 49483-49489 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T22 52230-52235 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T23 52802-52819 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T24 56007-56012 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T25 56058-56063 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T26 56344-56349 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T27 57602-57615 Body_part denotes cell clusters http://purl.obolibrary.org/obo/UBERON_0034922
T28 57972-57977 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T29 58426-58431 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T30 62144-62149 Body_part denotes mouth http://purl.obolibrary.org/obo/UBERON_0000165
T31 62274-62279 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T32 62578-62583 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T33 62852-62857 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T34 63487-63492 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T35 63635-63640 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T36 63708-63712 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T37 69779-69784 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T38 70258-70263 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T39 70839-70844 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T40 71422-71427 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T41 73688-73693 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T42 75648-75653 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T43 78545-78553 Body_part denotes Pancreas http://purl.obolibrary.org/obo/UBERON_0001264

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 34-42 Species denotes patients Tax:9606
3 25-33 Disease denotes COVID-19 MESH:C000657245
12 157-162 Species denotes human Tax:9606
13 244-252 Species denotes patients Tax:9606
14 463-471 Species denotes patients Tax:9606
15 487-495 Species denotes patients Tax:9606
16 112-120 Disease denotes COVID-19 MESH:C000657245
17 235-243 Disease denotes COVID-19 MESH:C000657245
18 542-557 Disease denotes viral infection MESH:D001102
19 1029-1037 Disease denotes COVID-19 MESH:C000657245
34 1162-1171 Species denotes SARS-CoV2 Tax:2697049
35 1182-1190 Species denotes patients Tax:9606
36 1402-1410 Species denotes patients Tax:9606
37 1044-1052 Disease denotes COVID-19 MESH:C000657245
38 1092-1102 Disease denotes infections MESH:D007239
39 1129-1135 Disease denotes deaths MESH:D003643
40 1147-1156 Disease denotes infection MESH:D007239
41 1173-1181 Disease denotes COVID-19 MESH:C000657245
42 1393-1401 Disease denotes COVID-19 MESH:C000657245
43 1422-1457 Disease denotes acute respiratory distress syndrome MESH:D012128
44 1459-1463 Disease denotes ARDS MESH:D012128
45 1484-1502 Disease denotes respiratory damage MESH:D012140
46 1513-1541 Disease denotes respiratory viral infections
47 1664-1672 Disease denotes COVID-19 MESH:C000657245
63 2153-2156 Gene denotes CD4 Gene:920
64 2236-2239 Gene denotes CD4 Gene:920
65 2427-2431 Gene denotes IL-6 Gene:3569
66 2436-2442 Gene denotes GM-CSF Gene:1437
67 2453-2456 Gene denotes CD4 Gene:920
68 2194-2197 Gene denotes CD8 Gene:925
69 2266-2279 Species denotes coronaviruses Tax:11118
70 2337-2346 Species denotes SARS-CoV2 Tax:2697049
71 2861-2869 Species denotes patients Tax:9606
72 1834-1843 Species denotes SARS-CoV2 Tax:2697049
73 2049-2058 Disease denotes infection MESH:D007239
74 2852-2860 Disease denotes COVID-19 MESH:C000657245
75 2943-2955 Disease denotes cytotoxicity MESH:D064420
76 3099-3107 Disease denotes COVID-19 MESH:C000657245
77 3108-3119 Disease denotes lymphopenia MESH:D008231
87 3150-3158 Species denotes patients Tax:9606
88 3446-3454 Species denotes patients Tax:9606
89 3635-3644 Species denotes SARS-CoV2 Tax:2697049
90 3805-3813 Species denotes patients Tax:9606
91 3191-3200 Disease denotes infection MESH:D007239
92 3327-3335 Disease denotes COVID-19 MESH:C000657245
93 3645-3654 Disease denotes infection MESH:D007239
94 3832-3840 Disease denotes COVID-19 MESH:C000657245
95 3965-3973 Disease denotes COVID-19 MESH:C000657245
101 4095-4104 Species denotes SARS-CoV2 Tax:2697049
102 4241-4249 Species denotes patients Tax:9606
103 4533-4541 Species denotes patients Tax:9606
104 4728-4735 Species denotes patient Tax:9606
105 4524-4532 Disease denotes COVID-19 MESH:C000657245
109 4752-4761 Species denotes SARS-CoV2 Tax:2697049
110 4775-4781 Species denotes humans Tax:9606
111 4762-4771 Disease denotes infection MESH:D007239
129 4898-4906 Species denotes patients Tax:9606
130 5027-5036 Species denotes SARS-CoV2 Tax:2697049
131 5057-5065 Species denotes patients Tax:9606
132 5191-5199 Species denotes patients Tax:9606
133 5283-5291 Species denotes patients Tax:9606
134 5326-5335 Species denotes SARS-CoV2 Tax:2697049
135 5503-5511 Species denotes patients Tax:9606
136 5564-5572 Species denotes patients Tax:9606
137 5644-5652 Species denotes patients Tax:9606
138 4912-4920 Disease denotes COVID-19 MESH:C000657245
139 5037-5046 Disease denotes infection MESH:D007239
140 5048-5056 Disease denotes COVID-19 MESH:C000657245
141 5336-5345 Disease denotes infection MESH:D007239
142 5411-5413 Disease denotes HD MESH:D006816
143 5494-5502 Disease denotes COVID-19 MESH:C000657245
144 5635-5643 Disease denotes COVID-19 MESH:C000657245
145 5682-5685 Disease denotes HDs
147 5792-5799 Species denotes patient Tax:9606
167 6330-6333 Gene denotes CD4 Gene:920
168 6334-6337 Gene denotes CD8 Gene:925
169 6375-6378 Gene denotes CD4 Gene:920
170 6379-6382 Gene denotes CD8 Gene:925
171 5891-5898 Species denotes patient Tax:9606
172 5984-5992 Species denotes patients Tax:9606
173 6052-6060 Species denotes patients Tax:9606
174 6085-6092 Species denotes patient Tax:9606
175 6222-6230 Species denotes patients Tax:9606
176 6423-6430 Species denotes patient Tax:9606
177 6785-6792 Species denotes patient Tax:9606
178 5943-5945 Disease denotes HD MESH:D006816
179 5975-5983 Disease denotes COVID-19 MESH:C000657245
180 6043-6051 Disease denotes COVID-19 MESH:C000657245
181 6076-6084 Disease denotes COVID-19 MESH:C000657245
182 6213-6221 Disease denotes COVID-19 MESH:C000657245
183 6531-6533 Disease denotes HD MESH:D006816
184 6603-6614 Disease denotes lymphopenia MESH:D008231
185 6776-6784 Disease denotes COVID-19 MESH:C000657245
205 6936-6944 Species denotes patients Tax:9606
206 7151-7159 Species denotes patients Tax:9606
207 7262-7270 Species denotes patients Tax:9606
208 7455-7463 Species denotes patients Tax:9606
209 7510-7518 Species denotes patients Tax:9606
210 7624-7632 Species denotes patients Tax:9606
211 7813-7821 Species denotes patients Tax:9606
212 7929-7937 Species denotes patients Tax:9606
213 7651-7669 Chemical denotes hydroxychloroquine MESH:D006886
214 7671-7674 Chemical denotes HCQ MESH:D006886
215 7686-7694 Chemical denotes steroids MESH:D013256
216 7709-7719 Chemical denotes remdesivir MESH:C000606551
217 6927-6935 Disease denotes COVID-19 MESH:C000657245
218 7002-7004 Disease denotes HD MESH:D006816
219 7142-7150 Disease denotes COVID-19 MESH:C000657245
220 7253-7261 Disease denotes COVID-19 MESH:C000657245
221 7375-7397 Disease denotes chronic kidney disease MESH:D051436
222 7421-7435 Disease denotes thromboembolic MESH:D013923
223 7553-7559 Disease denotes cancer MESH:D009369
243 8186-8204 Gene denotes C reactive protein Gene:1401
244 8206-8209 Gene denotes CRP Gene:1401
245 8517-8521 Gene denotes IL-6 Gene:3569
246 8993-8999 Gene denotes ALC <1 Gene:9557
247 8101-8109 Species denotes patients Tax:9606
248 8359-8367 Species denotes patients Tax:9606
249 8449-8457 Species denotes patients Tax:9606
250 8485-8493 Species denotes patients Tax:9606
251 8546-8554 Species denotes patients Tax:9606
252 8581-8589 Species denotes patients Tax:9606
253 8619-8627 Species denotes patients Tax:9606
254 8772-8780 Species denotes patients Tax:9606
255 8804-8812 Species denotes patients Tax:9606
256 8955-8963 Species denotes patients Tax:9606
257 8092-8100 Disease denotes COVID-19 MESH:C000657245
258 8121-8129 Disease denotes COVID-19 MESH:C000657245
259 8350-8358 Disease denotes COVID-19 MESH:C000657245
260 8763-8771 Disease denotes COVID-19 MESH:C000657245
261 8946-8954 Disease denotes COVID-19 MESH:C000657245
270 9572-9576 Gene denotes IL-6 Gene:3569
271 9866-9874 Species denotes patients Tax:9606
272 9987-9995 Species denotes patients Tax:9606
273 9295-9303 Disease denotes COVID-19 MESH:C000657245
274 9686-9695 Disease denotes mortality MESH:D003643
275 9794-9806 Disease denotes inflammation MESH:D007249
276 9857-9865 Disease denotes COVID-19 MESH:C000657245
277 9966-9978 Disease denotes inflammation MESH:D007249
298 10880-10883 Gene denotes CD4 Gene:920
299 11017-11020 Gene denotes CD4 Gene:920
300 11025-11028 Gene denotes CD8 Gene:925
301 11151-11154 Gene denotes CD8 Gene:925
302 11202-11205 Gene denotes CD4 Gene:920
303 11394-11397 Gene denotes CD8 Gene:925
304 10856-10859 Gene denotes CD8 Gene:925
305 10088-10097 Species denotes SARS-CoV2 Tax:2697049
306 10175-10183 Species denotes patients Tax:9606
307 10360-10368 Species denotes patients Tax:9606
308 11055-11063 Species denotes patients Tax:9606
309 10098-10107 Disease denotes infection MESH:D007239
310 10166-10174 Disease denotes COVID-19 MESH:C000657245
311 10193-10195 Disease denotes HD MESH:D006816
312 10351-10359 Disease denotes COVID-19 MESH:C000657245
313 10381-10383 Disease denotes HD MESH:D006816
314 10420-10431 Disease denotes lymphopenia MESH:D008231
315 11046-11054 Disease denotes COVID-19 MESH:C000657245
316 11311-11322 Disease denotes lymphopenia MESH:D008231
317 11330-11338 Disease denotes COVID-19 MESH:C000657245
323 11586-11589 Gene denotes CD4 Gene:920
324 11594-11597 Gene denotes CD8 Gene:925
325 11868-11876 Species denotes patients Tax:9606
326 11732-11744 Disease denotes inflammation MESH:D007249
327 11859-11867 Disease denotes COVID-19 MESH:C000657245
331 12035-12038 Gene denotes CD8 Gene:925
332 11996-12005 Species denotes SARS-CoV2 Tax:2697049
333 12006-12015 Disease denotes infection MESH:D007239
372 12743-12746 Gene denotes CD8 Gene:925
373 12766-12769 Gene denotes CD8 Gene:925
374 12836-12840 Gene denotes CD27 Gene:939
375 12842-12846 Gene denotes CCR7 Gene:1236
376 12852-12856 Gene denotes CD95 Gene:355
377 12902-12906 Gene denotes CD27 Gene:939
378 12907-12911 Gene denotes CCR7 Gene:1236
379 12912-12916 Gene denotes CD95 Gene:355
380 12943-12947 Gene denotes CD27 Gene:939
381 12948-12952 Gene denotes CCR7 Gene:1236
382 12985-12989 Gene denotes CD27 Gene:939
383 12990-12994 Gene denotes CCR7 Gene:1236
384 13010-13014 Gene denotes CD27 Gene:939
385 13015-13019 Gene denotes CCR7 Gene:1236
386 13035-13039 Gene denotes CD27 Gene:939
387 13040-13044 Gene denotes CCR7 Gene:1236
388 13071-13075 Gene denotes CD27 Gene:939
389 13076-13080 Gene denotes CCR7 Gene:1236
390 13093-13096 Gene denotes CD8 Gene:925
391 13116-13119 Gene denotes CD8 Gene:925
392 13257-13261 Gene denotes CD39 Gene:953
393 13356-13360 Gene denotes PD-1 Gene:100513601
394 13399-13402 Gene denotes CD8 Gene:925
395 13493-13496 Gene denotes CD8 Gene:925
396 12347-12355 Species denotes patients Tax:9606
397 12499-12507 Species denotes patients Tax:9606
398 13295-13303 Species denotes patients Tax:9606
399 12211-12219 Disease denotes COVID-19 MESH:C000657245
400 12338-12346 Disease denotes COVID-19 MESH:C000657245
401 12384-12386 Disease denotes HD MESH:D006816
402 12490-12498 Disease denotes COVID-19 MESH:C000657245
403 12539-12541 Disease denotes HD MESH:D006816
404 12571-12573 Disease denotes HD MESH:D006816
405 12653-12661 Disease denotes COVID-19 MESH:C000657245
406 12712-12727 Disease denotes viral infection MESH:D001102
407 13286-13294 Disease denotes COVID-19 MESH:C000657245
408 13316-13318 Disease denotes HD MESH:D006816
409 13554-13556 Disease denotes HD MESH:D006816
413 13598-13601 Gene denotes CD8 Gene:925
414 13660-13668 Species denotes patients Tax:9606
415 13651-13659 Disease denotes COVID-19 MESH:C000657245
433 13858-13861 Gene denotes CD8 Gene:925
434 13897-13900 Gene denotes CD8 Gene:925
435 13958-13962 Gene denotes CD39 Gene:397298
436 14011-14015 Gene denotes CD38 Gene:952
437 14551-14554 Gene denotes CD8 Gene:925
440 13949-13952 Gene denotes PD1 Gene:100513601
441 14145-14148 Gene denotes CD8 Gene:925
445 14094-14096 Disease denotes HD MESH:D006816
446 42977-42979 Disease denotes HD MESH:D006816
447 43008-43016 Disease denotes COVID-19 MESH:C000657245
492 14952-14955 Gene denotes CD8 Gene:925
493 15016-15020 Gene denotes CD38 Gene:952
494 15100-15104 Gene denotes CD38 Gene:952
495 15116-15119 Gene denotes CD8 Gene:925
496 15217-15220 Gene denotes CD8 Gene:925
497 15298-15301 Gene denotes CD8 Gene:925
498 15591-15595 Gene denotes CD38 Gene:952
499 15661-15664 Gene denotes CD8 Gene:925
500 15743-15747 Gene denotes CD38 Gene:952
501 15756-15759 Gene denotes CD8 Gene:925
502 15821-15824 Gene denotes CD8 Gene:925
503 15866-15870 Gene denotes CD38 Gene:952
504 15879-15882 Gene denotes CD8 Gene:925
505 15929-15933 Gene denotes CD38 Gene:952
506 15957-15960 Gene denotes CD8 Gene:925
507 16176-16179 Gene denotes CD8 Gene:925
508 16361-16364 Gene denotes CD8 Gene:925
509 16389-16393 Gene denotes IL-6 Gene:3569
510 16424-16427 Gene denotes CD8 Gene:925
511 16503-16507 Gene denotes CD38 Gene:952
512 16516-16519 Gene denotes CD8 Gene:925
513 16597-16600 Gene denotes CD8 Gene:925
514 16744-16747 Gene denotes CD8 Gene:925
515 15524-15527 Gene denotes CD8 Gene:925
516 15140-15148 Species denotes patients Tax:9606
517 15201-15209 Species denotes patients Tax:9606
518 15995-16003 Species denotes patients Tax:9606
519 16207-16215 Species denotes patients Tax:9606
520 16466-16474 Species denotes patients Tax:9606
521 16676-16684 Species denotes patients Tax:9606
522 16712-16720 Species denotes patients Tax:9606
523 16128-16136 Chemical denotes steroids MESH:D013256
524 14896-14912 Disease denotes viral infections MESH:D001102
525 15131-15139 Disease denotes COVID-19 MESH:C000657245
526 15161-15163 Disease denotes HD MESH:D006816
527 15192-15200 Disease denotes COVID-19 MESH:C000657245
528 15256-15258 Disease denotes HD MESH:D006816
529 15986-15994 Disease denotes COVID-19 MESH:C000657245
530 16024-16033 Disease denotes infection MESH:D007239
531 16198-16206 Disease denotes COVID-19 MESH:C000657245
532 16553-16555 Disease denotes HD MESH:D006816
533 16667-16675 Disease denotes COVID-19 MESH:C000657245
573 16979-16982 Gene denotes CD8 Gene:925
574 17129-17132 Gene denotes CD8 Gene:925
575 17173-17177 Gene denotes CD38 Gene:952
576 17193-17197 Gene denotes CD39 Gene:953
577 17203-17206 Gene denotes PD1 Gene:6622
578 17307-17311 Gene denotes CD95 Gene:355
579 17353-17356 Gene denotes CD8 Gene:925
580 17484-17489 Gene denotes T-bet Gene:30009
581 17494-17500 Gene denotes CX3CR1 Gene:1524
582 17679-17682 Gene denotes CD8 Gene:925
583 17871-17875 Gene denotes CD27 Gene:939
584 17876-17880 Gene denotes CCR7 Gene:1236
585 17920-17926 Gene denotes CX3CR1 Gene:1524
586 17949-17954 Gene denotes T-bet Gene:30009
587 18003-18007 Gene denotes CD27 Gene:100520023
588 18015-18019 Gene denotes CD38 Gene:100511702
589 18025-18029 Gene denotes PD-1 Gene:100513601
590 18177-18181 Gene denotes CD27 Gene:939
591 18182-18186 Gene denotes CCR7 Gene:1236
592 18306-18309 Gene denotes CD8 Gene:925
593 18410-18413 Gene denotes CD8 Gene:925
594 18164-18169 Gene denotes Eomes Gene:8320
595 17024-17032 Species denotes patients Tax:9606
596 17096-17104 Species denotes patients Tax:9606
597 17578-17586 Species denotes patients Tax:9606
598 17715-17727 Species denotes cluster (Fig Tax:100569
599 17843-17851 Species denotes patients Tax:9606
600 18339-18347 Species denotes patients Tax:9606
601 18439-18447 Species denotes patients Tax:9606
602 18226-18233 Species denotes Cluster Tax:100569
603 17015-17023 Disease denotes COVID-19 MESH:C000657245
604 17087-17095 Disease denotes COVID-19 MESH:C000657245
605 17114-17116 Disease denotes HD MESH:D006816
606 17407-17409 Disease denotes HD MESH:D006816
607 17569-17577 Disease denotes COVID-19 MESH:C000657245
608 17834-17842 Disease denotes COVID-19 MESH:C000657245
609 18089-18097 Disease denotes COVID-19 MESH:C000657245
610 18264-18266 Disease denotes HD MESH:D006816
611 18330-18338 Disease denotes COVID-19 MESH:C000657245
616 18503-18506 Gene denotes CD4 Gene:920
617 18542-18545 Gene denotes CD4 Gene:920
618 18450-18459 Species denotes SARS-CoV2 Tax:2697049
619 18460-18469 Disease denotes infection MESH:D007239
680 18595-18598 Gene denotes CD4 Gene:920
681 18631-18634 Gene denotes CD8 Gene:925
682 18852-18857 Gene denotes CXCR5 Gene:643
683 18903-18907 Gene denotes CD38 Gene:952
684 18908-18912 Gene denotes ICOS Gene:29851
685 19113-19116 Gene denotes CD4 Gene:920
686 19560-19564 Gene denotes CD38 Gene:952
687 19583-19586 Gene denotes CD4 Gene:920
688 19701-19704 Gene denotes CD4 Gene:920
689 19770-19774 Gene denotes CD38 Gene:952
690 20092-20096 Gene denotes CD38 Gene:952
691 20121-20124 Gene denotes CD4 Gene:920
692 20182-20185 Gene denotes CD4 Gene:920
693 20249-20252 Gene denotes CD4 Gene:920
694 20271-20275 Gene denotes CD38 Gene:952
695 20374-20377 Gene denotes CD4 Gene:920
696 20424-20427 Gene denotes CD8 Gene:925
697 20509-20512 Gene denotes CD4 Gene:920
698 20516-20519 Gene denotes CD8 Gene:925
699 20623-20626 Gene denotes CD4 Gene:920
700 20630-20633 Gene denotes CD8 Gene:925
701 20757-20760 Gene denotes CD4 Gene:920
702 20781-20784 Gene denotes CD8 Gene:925
703 20867-20870 Gene denotes CD4 Gene:920
704 20891-20894 Gene denotes CD8 Gene:925
705 20932-20936 Gene denotes CD38 Gene:952
706 20955-20958 Gene denotes CD4 Gene:920
707 21075-21078 Gene denotes CD4 Gene:920
708 21152-21155 Gene denotes CD4 Gene:920
709 21240-21243 Gene denotes CD4 Gene:920
710 21523-21527 Gene denotes CD38 Gene:952
711 19978-19981 Gene denotes PD1 Gene:6622
712 18848-18851 Gene denotes PD1 Gene:6622
713 18787-18796 Species denotes SARS-CoV2 Tax:2697049
714 19271-19279 Species denotes patients Tax:9606
715 19354-19362 Species denotes patients Tax:9606
716 19622-19630 Species denotes patients Tax:9606
717 20480-20488 Species denotes patients Tax:9606
718 20576-20584 Species denotes patients Tax:9606
719 20711-20719 Species denotes patients Tax:9606
720 20818-20826 Species denotes patients Tax:9606
721 21329-21337 Species denotes patients Tax:9606
722 21446-21454 Species denotes patients Tax:9606
723 19161-19164 Chemical denotes EM2
724 19169-19173 Chemical denotes EMRA
725 19226-19230 Chemical denotes cTfh
726 19408-19412 Chemical denotes cTfh
727 19857-19861 Chemical denotes cTfh
728 20327-20331 Chemical denotes cTfh
729 21190-21197 Chemical denotes steroid MESH:D013256
730 19262-19270 Disease denotes COVID-19 MESH:C000657245
731 19292-19294 Disease denotes HD MESH:D006816
732 19460-19462 Disease denotes HD MESH:D006816
733 19502-19510 Disease denotes COVID-19 MESH:C000657245
734 19613-19621 Disease denotes COVID-19 MESH:C000657245
735 20054-20056 Disease denotes HD MESH:D006816
736 20567-20575 Disease denotes COVID-19 MESH:C000657245
737 20665-20667 Disease denotes HD MESH:D006816
738 21320-21328 Disease denotes COVID-19 MESH:C000657245
739 21381-21397 Disease denotes acute infections MESH:D007239
744 21574-21577 Gene denotes CD4 Gene:920
745 21654-21657 Gene denotes CD4 Gene:920
746 21620-21628 Species denotes patients Tax:9606
747 21611-21619 Disease denotes COVID-19 MESH:C000657245
773 21741-21744 Gene denotes CD4 Gene:920
774 21780-21783 Gene denotes CD4 Gene:920
775 21964-21967 Gene denotes CD4 Gene:920
776 21993-21996 Gene denotes CD8 Gene:925
777 22075-22079 Gene denotes CD38 Gene:952
778 22187-22191 Gene denotes CD38 Gene:952
779 22214-22217 Gene denotes CD4 Gene:920
780 22235-22238 Gene denotes CD8 Gene:925
781 22338-22341 Gene denotes CD4 Gene:920
782 22385-22388 Gene denotes CD4 Gene:920
783 22553-22556 Gene denotes CD4 Gene:920
784 22710-22713 Gene denotes CD4 Gene:920
785 22039-22047 Species denotes patients Tax:9606
786 22281-22289 Species denotes patients Tax:9606
787 22423-22431 Species denotes patients Tax:9606
788 22899-22906 Species denotes patient Tax:9606
789 22755-22762 Species denotes cluster Tax:100569
790 21891-21893 Disease denotes HD MESH:D006816
791 22030-22038 Disease denotes COVID-19 MESH:C000657245
792 22134-22136 Disease denotes HD MESH:D006816
793 22272-22280 Disease denotes COVID-19 MESH:C000657245
794 22402-22404 Disease denotes HD MESH:D006816
795 22414-22422 Disease denotes COVID-19 MESH:C000657245
796 22847-22849 Disease denotes HD MESH:D006816
797 22890-22898 Disease denotes COVID-19 MESH:C000657245
827 23063-23066 Gene denotes CD4 Gene:920
828 23178-23181 Gene denotes CD4 Gene:920
829 23367-23371 Gene denotes CD38 Gene:952
830 23381-23384 Gene denotes PD1 Gene:6622
831 23386-23390 Gene denotes CD39 Gene:953
832 23402-23406 Gene denotes CD95 Gene:355
833 23429-23432 Gene denotes CD8 Gene:925
834 23474-23477 Gene denotes CD4 Gene:920
835 23705-23709 Gene denotes CD38 Gene:952
836 23711-23714 Gene denotes PD1 Gene:6622
837 23725-23729 Gene denotes CD95 Gene:355
838 23768-23772 Gene denotes Tbet Gene:30009
839 23773-23779 Gene denotes CX3CR1 Gene:1524
840 23797-23800 Gene denotes CD4 Gene:920
841 23904-23909 Gene denotes CXCR5 Gene:643
842 24102-24105 Gene denotes CD4 Gene:920
843 23628-23636 Species denotes patients Tax:9606
844 24145-24153 Species denotes patients Tax:9606
845 23742-23749 Species denotes Cluster Tax:100569
846 23205-23213 Disease denotes COVID-19 MESH:C000657245
847 23214-23223 Disease denotes infection MESH:D007239
848 23236-23239 Disease denotes HDs
849 23262-23270 Disease denotes COVID-19 MESH:C000657245
850 23271-23280 Disease denotes infection MESH:D007239
851 23619-23627 Disease denotes COVID-19 MESH:C000657245
852 23649-23651 Disease denotes HD MESH:D006816
853 23946-23954 Disease denotes COVID-19 MESH:C000657245
854 23976-23978 Disease denotes HD MESH:D006816
855 24136-24144 Disease denotes COVID-19 MESH:C000657245
908 24366-24372 Gene denotes IL-1RA Gene:3557
909 24374-24378 Gene denotes IL-6 Gene:3569
910 24380-24384 Gene denotes IL-8 Gene:3576
911 24386-24391 Gene denotes IL-10 Gene:3586
912 24397-24403 Gene denotes CXCL10 Gene:3627
913 24597-24601 Gene denotes CD28 Gene:940
914 24878-24884 Gene denotes CXCL10 Gene:3627
915 25009-25014 Gene denotes CXCL9 Gene:4283
916 25016-25020 Gene denotes CCL2 Gene:6347
917 25026-25032 Gene denotes IL-1RA Gene:3557
918 25136-25143 Gene denotes eotaxin Gene:6356
919 25167-25171 Gene denotes CCL5 Gene:6352
920 25189-25193 Gene denotes IL-6 Gene:3569
921 25329-25333 Gene denotes IL-6 Gene:3569
922 25493-25497 Gene denotes CCL2 Gene:6347
923 25499-25505 Gene denotes CXCL10 Gene:3627
924 25507-25514 Gene denotes eotaxin Gene:6356
925 25520-25526 Gene denotes IL-1RA Gene:3557
926 25576-25582 Gene denotes CXCL10 Gene:3627
927 25587-25591 Gene denotes CCL2 Gene:6347
928 25720-25723 Gene denotes CD8 Gene:925
929 25781-25785 Gene denotes IFNɣ Gene:3458
930 25877-25880 Gene denotes CD8 Gene:925
931 25937-25941 Gene denotes IFNɣ Gene:3458
932 26076-26080 Gene denotes IFNɣ Gene:3458
933 24254-24262 Species denotes patients Tax:9606
934 24644-24652 Species denotes patients Tax:9606
935 24721-24728 Species denotes patient Tax:9606
936 24763-24772 Species denotes SARS-CoV2 Tax:2697049
937 24858-24866 Species denotes patients Tax:9606
938 25228-25236 Species denotes patients Tax:9606
939 25470-25478 Species denotes patients Tax:9606
940 25903-25911 Species denotes patients Tax:9606
941 25978-25986 Species denotes patients Tax:9606
942 26115-26123 Species denotes patients Tax:9606
943 26158-26166 Species denotes patients Tax:9606
944 26274-26282 Species denotes patients Tax:9606
945 25835-25840 Chemical denotes ɑCD28
946 24172-24180 Disease denotes COVID-19 MESH:C000657245
947 24635-24643 Disease denotes COVID-19 MESH:C000657245
948 24657-24659 Disease denotes HD MESH:D006816
949 24712-24720 Disease denotes COVID-19 MESH:C000657245
950 24849-24857 Disease denotes COVID-19 MESH:C000657245
951 24931-24933 Disease denotes HD MESH:D006816
952 25391-25403 Disease denotes inflammation MESH:D007249
953 25461-25469 Disease denotes COVID-19 MESH:C000657245
954 25532-25534 Disease denotes HD MESH:D006816
955 25737-25745 Disease denotes COVID-19 MESH:C000657245
956 25894-25902 Disease denotes COVID-19 MESH:C000657245
957 25916-25918 Disease denotes HD MESH:D006816
958 25969-25977 Disease denotes COVID-19 MESH:C000657245
959 26265-26273 Disease denotes COVID-19 MESH:C000657245
962 26373-26381 Disease denotes COVID-19 MESH:C000657245
963 26382-26391 Disease denotes infection MESH:D007239
1000 26673-26677 Gene denotes CD27 Gene:939
1001 26708-26712 Gene denotes CD27 Gene:939
1002 26795-26799 Gene denotes CD27 Gene:939
1003 26817-26821 Gene denotes CD27 Gene:939
1004 26822-26826 Gene denotes CD38 Gene:952
1005 27517-27522 Gene denotes CXCR5 Gene:643
1006 27619-27624 Gene denotes CXCR5 Gene:643
1007 27709-27712 Gene denotes CD4 Gene:920
1008 27918-27922 Gene denotes IL-6 Gene:3569
1009 26611-26619 Species denotes patients Tax:9606
1010 26975-26980 Species denotes Ebola Tax:1570291
1011 27076-27084 Species denotes patients Tax:9606
1012 27105-27113 Species denotes patients Tax:9606
1013 27251-27259 Species denotes patients Tax:9606
1014 27486-27494 Species denotes patients Tax:9606
1015 27591-27599 Species denotes patients Tax:9606
1016 26895-26897 Chemical denotes PB
1017 27033-27035 Chemical denotes PB
1018 27125-27127 Chemical denotes PB
1019 27429-27433 Chemical denotes KI67
1020 27437-27439 Chemical denotes PB
1021 27839-27847 Chemical denotes steroids MESH:D013256
1022 26535-26543 Disease denotes COVID-19 MESH:C000657245
1023 26602-26610 Disease denotes COVID-19 MESH:C000657245
1024 26630-26632 Disease denotes HD MESH:D006816
1025 26984-27007 Disease denotes Dengue virus infections MESH:D003715
1026 27151-27153 Disease denotes HD MESH:D006816
1027 27242-27250 Disease denotes COVID-19 MESH:C000657245
1028 27371-27380 Disease denotes infection MESH:D007239
1029 27388-27399 Disease denotes lymphopenia MESH:D008231
1030 27477-27485 Disease denotes COVID-19 MESH:C000657245
1031 27507-27509 Disease denotes HD MESH:D006816
1032 27582-27590 Disease denotes COVID-19 MESH:C000657245
1033 27787-27799 Disease denotes co-infection MESH:D060085
1034 28020-28028 Disease denotes COVID-19 MESH:C000657245
1035 28068-28080 Disease denotes inflammation MESH:D007249
1038 28117-28124 Species denotes patient Tax:9606
1039 28108-28116 Disease denotes COVID-19 MESH:C000657245
1054 28486-28491 Gene denotes CXCR5 Gene:643
1055 28515-28520 Gene denotes CXCR5 Gene:643
1056 28549-28554 Gene denotes CXCR5 Gene:643
1057 28573-28576 Gene denotes CD4 Gene:920
1058 29038-29043 Gene denotes Mover Gene:127262
1059 29482-29489 Species denotes cluster Tax:100569
1060 28696-28705 Species denotes SARS-CoV2 Tax:2697049
1061 28774-28783 Species denotes SARS-CoV2 Tax:2697049
1062 28589-28593 Chemical denotes cTfh
1063 28628-28630 Chemical denotes PB
1064 28645-28649 Chemical denotes cTfh
1065 28368-28370 Disease denotes HD MESH:D006816
1066 29565-29567 Disease denotes HD MESH:D006816
1067 29608-29616 Disease denotes COVID-19 MESH:C000657245
1100 30363-30374 Gene denotes S5, B and C Gene:6193
1101 30441-30445 Gene denotes CD38 Gene:952
1102 30463-30466 Gene denotes CD4 Gene:920
1103 30509-30514 Gene denotes CXCR5 Gene:643
1104 30516-30519 Gene denotes CD4 Gene:920
1105 30601-30604 Gene denotes CD8 Gene:925
1106 30131-30142 Gene denotes S5, B and C Gene:6193
1107 30163-30171 Species denotes patients Tax:9606
1108 30262-30270 Species denotes patients Tax:9606
1109 30662-30670 Species denotes patients Tax:9606
1110 30704-30713 Species denotes SARS-CoV2 Tax:2697049
1111 30940-30948 Species denotes patients Tax:9606
1112 31366-31375 Species denotes SARS-CoV2 Tax:2697049
1113 31615-31624 Species denotes SARS-CoV2 Tax:2697049
1114 31084-31093 Species denotes SARS-CoV2 Tax:2697049
1115 31215-31224 Species denotes SARS-CoV2 Tax:2697049
1116 29878-29880 Chemical denotes PB
1117 29950-29954 Chemical denotes cTfh
1118 29998-30000 Chemical denotes PB
1119 30027-30031 Chemical denotes cTfh
1120 30045-30049 Chemical denotes cTfh
1121 30108-30112 Chemical denotes cTfh
1122 30193-30197 Chemical denotes cTfh
1123 30212-30214 Chemical denotes PB
1124 30283-30285 Chemical denotes PB
1125 30340-30344 Chemical denotes cTfh
1126 31290-31294 Chemical denotes cTfh
1127 31346-31350 Chemical denotes cTfh
1128 31587-31589 Chemical denotes PB
1129 29845-29861 Disease denotes viral infections MESH:D001102
1130 30653-30661 Disease denotes COVID-19 MESH:C000657245
1131 31139-31151 Disease denotes inflammation MESH:D007249
1189 31924-31929 Gene denotes CXCR5 Gene:643
1190 32073-32077 Gene denotes CD27 Gene:939
1191 32079-32083 Gene denotes CD38 Gene:952
1192 32085-32090 Gene denotes CD138 Gene:6382
1193 32139-32143 Gene denotes CD95 Gene:355
1194 32153-32157 Gene denotes CD27 Gene:939
1195 32158-32162 Gene denotes CD38 Gene:952
1196 32163-32168 Gene denotes CD138 Gene:6382
1197 33302-33306 Gene denotes CD27 Gene:939
1198 33325-33330 Gene denotes CXCR5 Gene:643
1199 33721-33726 Gene denotes T-bet Gene:30009
1200 33783-33787 Gene denotes CD27 Gene:939
1201 33788-33792 Gene denotes CD38 Gene:952
1202 33793-33798 Gene denotes CD138 Gene:6382
1203 34075-34080 Gene denotes T-bet Gene:30009
1204 34317-34322 Gene denotes T-bet Gene:30009
1205 34351-34356 Gene denotes CXCR5 Gene:643
1206 31699-31707 Species denotes patients Tax:9606
1207 31874-31881 Species denotes patient Tax:9606
1208 32318-32326 Species denotes patients Tax:9606
1209 32648-32656 Species denotes patients Tax:9606
1210 32807-32815 Species denotes patients Tax:9606
1211 33080-33088 Species denotes patients Tax:9606
1212 33439-33447 Species denotes patients Tax:9606
1213 33667-33675 Species denotes patients Tax:9606
1214 33848-33856 Species denotes patients Tax:9606
1215 33946-33954 Species denotes patients Tax:9606
1216 34214-34222 Species denotes patients Tax:9606
1217 34542-34550 Species denotes patients Tax:9606
1218 34642-34650 Species denotes patients Tax:9606
1219 33309-33316 Species denotes Cluster Tax:100569
1220 33358-33365 Species denotes Cluster Tax:100569
1221 33759-33766 Species denotes Cluster Tax:100569
1222 34012-34019 Species denotes Cluster Tax:100569
1223 34096-34103 Species denotes Cluster Tax:100569
1224 32005-32007 Chemical denotes PB
1225 31678-31680 Disease denotes HD MESH:D006816
1226 31690-31698 Disease denotes COVID-19 MESH:C000657245
1227 31775-31783 Disease denotes COVID-19 MESH:C000657245
1228 31821-31823 Disease denotes HD MESH:D006816
1229 31865-31873 Disease denotes COVID-19 MESH:C000657245
1230 31963-31965 Disease denotes HD MESH:D006816
1231 32309-32317 Disease denotes COVID-19 MESH:C000657245
1232 32331-32333 Disease denotes HD MESH:D006816
1233 32639-32647 Disease denotes COVID-19 MESH:C000657245
1234 32798-32806 Disease denotes COVID-19 MESH:C000657245
1235 32858-32860 Disease denotes HD MESH:D006816
1236 32974-32983 Disease denotes infection MESH:D007239
1237 33060-33062 Disease denotes HD MESH:D006816
1238 33071-33079 Disease denotes COVID-19 MESH:C000657245
1239 33256-33258 Disease denotes HD MESH:D006816
1240 33430-33438 Disease denotes COVID-19 MESH:C000657245
1241 33658-33666 Disease denotes COVID-19 MESH:C000657245
1242 33839-33847 Disease denotes COVID-19 MESH:C000657245
1243 33937-33945 Disease denotes COVID-19 MESH:C000657245
1244 34205-34213 Disease denotes COVID-19 MESH:C000657245
1245 34533-34541 Disease denotes COVID-19 MESH:C000657245
1247 34760-34768 Disease denotes COVID-19 MESH:C000657245
1261 34922-34925 Gene denotes CD8 Gene:925
1262 34934-34937 Gene denotes CD4 Gene:920
1263 35204-35207 Gene denotes CD4 Gene:920
1264 35315-35318 Gene denotes CD8 Gene:925
1265 35376-35380 Gene denotes CD38 Gene:952
1266 35389-35392 Gene denotes CD8 Gene:925
1267 35529-35532 Gene denotes CD4 Gene:920
1268 35192-35195 Gene denotes CD8 Gene:925
1269 34818-34826 Species denotes patients Tax:9606
1270 35104-35112 Species denotes patients Tax:9606
1271 35442-35450 Species denotes patients Tax:9606
1272 34809-34817 Disease denotes COVID-19 MESH:C000657245
1273 35433-35441 Disease denotes COVID-19 MESH:C000657245
1291 35715-35718 Gene denotes CD8 Gene:925
1292 35738-35741 Gene denotes CD4 Gene:920
1293 35898-35902 Gene denotes CD38 Gene:952
1294 35904-35907 Gene denotes CD4 Gene:920
1295 35938-35942 Gene denotes CD38 Gene:952
1296 35944-35947 Gene denotes CD8 Gene:925
1297 36290-36294 Gene denotes CD38 Gene:952
1298 36296-36299 Gene denotes CD4 Gene:920
1299 35813-35821 Species denotes patients Tax:9606
1300 36052-36060 Species denotes patients Tax:9606
1301 36331-36339 Species denotes patients Tax:9606
1302 35964-35967 Chemical denotes PBs MESH:D007854
1303 36315-36318 Chemical denotes PBs MESH:D007854
1304 35804-35812 Disease denotes COVID-19 MESH:C000657245
1305 36000-36002 Disease denotes HD MESH:D006816
1306 36043-36051 Disease denotes COVID-19 MESH:C000657245
1307 36322-36330 Disease denotes COVID-19 MESH:C000657245
1313 36712-36715 Gene denotes CD4 Gene:920
1314 36720-36723 Gene denotes CD8 Gene:925
1315 36810-36814 Gene denotes CD38 Gene:952
1316 36836-36839 Gene denotes CD4 Gene:920
1317 36870-36873 Gene denotes CD8 Gene:925
1352 37538-37542 Gene denotes CD38 Gene:952
1353 37554-37557 Gene denotes CD4 Gene:920
1354 37690-37693 Gene denotes CD8 Gene:925
1355 37789-37792 Gene denotes CD8 Gene:925
1356 37947-37950 Gene denotes CD8 Gene:925
1357 38077-38080 Gene denotes CD8 Gene:925
1358 38167-38171 Gene denotes CD38 Gene:952
1359 38183-38186 Gene denotes CD8 Gene:925
1360 38373-38376 Gene denotes CD8 Gene:925
1361 38381-38384 Gene denotes CD4 Gene:920
1362 38486-38489 Gene denotes CD8 Gene:925
1363 38494-38497 Gene denotes CD4 Gene:920
1364 37053-37061 Species denotes patients Tax:9606
1365 37147-37154 Species denotes patient Tax:9606
1366 37366-37374 Species denotes patients Tax:9606
1367 37503-37511 Species denotes patients Tax:9606
1368 37596-37604 Species denotes patients Tax:9606
1369 37874-37882 Species denotes patients Tax:9606
1370 38218-38226 Species denotes patients Tax:9606
1371 38547-38555 Species denotes smallpox Tax:10255
1372 38578-38592 Species denotes vaccinia virus Tax:10245
1373 38739-38747 Species denotes patients Tax:9606
1374 38845-38853 Species denotes patients Tax:9606
1375 38966-38974 Species denotes patients Tax:9606
1376 39021-39029 Species denotes patients Tax:9606
1377 38762-38764 Chemical denotes PB
1378 37357-37365 Disease denotes COVID-19 MESH:C000657245
1379 38016-38018 Disease denotes HD MESH:D006816
1380 38114-38123 Disease denotes infection MESH:D007239
1381 38428-38443 Disease denotes viral infection MESH:D001102
1382 38519-38535 Disease denotes viral infections MESH:D001102
1383 38622-38627 Disease denotes fever MESH:D005334
1384 38666-38681 Disease denotes virus infection MESH:D001102
1385 38692-38711 Disease denotes acute HIV infection MESH:D015658
1421 39471-39474 Gene denotes CD4 Gene:920
1422 39479-39482 Gene denotes CD8 Gene:925
1423 39499-39503 Gene denotes CD38 Gene:952
1424 39697-39700 Gene denotes CD4 Gene:920
1425 39705-39708 Gene denotes CD8 Gene:925
1426 39716-39720 Gene denotes CD38 Gene:952
1427 39798-39802 Gene denotes CD38 Gene:952
1428 39804-39807 Gene denotes CD4 Gene:920
1429 40029-40032 Gene denotes CD4 Gene:920
1430 40630-40634 Gene denotes CD38 Gene:952
1431 40643-40646 Gene denotes CD8 Gene:925
1432 40826-40830 Gene denotes CD38 Gene:952
1433 40839-40842 Gene denotes CD8 Gene:925
1434 40037-40040 Gene denotes CD8 Gene:925
1435 40449-40457 Species denotes patients Tax:9606
1436 40527-40535 Species denotes patients Tax:9606
1437 40602-40610 Species denotes patients Tax:9606
1438 40791-40799 Species denotes patients Tax:9606
1439 40972-40980 Species denotes patients Tax:9606
1440 41206-41214 Species denotes patients Tax:9606
1441 40105-40114 Species denotes SARS-CoV2 Tax:2697049
1442 39910-39914 Chemical denotes cTfh
1443 40295-40305 Chemical denotes Remdesivir MESH:C000606551
1444 40310-40313 Chemical denotes HCQ MESH:D006886
1445 40474-40476 Chemical denotes PB
1446 40552-40554 Chemical denotes PB
1447 40732-40744 Chemical denotes nitric oxide MESH:D009569
1448 40907-40919 Chemical denotes nitric oxide MESH:D009569
1449 40931-40938 Chemical denotes steroid MESH:D013256
1450 39270-39278 Disease denotes COVID-19 MESH:C000657245
1451 39658-39669 Disease denotes lymphopenia MESH:D008231
1452 39841-39866 Disease denotes coagulation complications MESH:D001778
1453 39940-39952 Disease denotes co-infection MESH:D060085
1454 40491-40505 Disease denotes hyperlipidemia MESH:D006949
1455 41197-41205 Disease denotes COVID-19 MESH:C000657245
1457 41383-41391 Disease denotes COVID-19 MESH:C000657245
1474 41927-41930 Gene denotes CD8 Gene:925
1475 41935-41938 Gene denotes CD4 Gene:920
1476 41973-41976 Gene denotes CD8 Gene:925
1477 42235-42239 Gene denotes CD38 Gene:952
1478 42241-42244 Gene denotes CD8 Gene:925
1479 42286-42290 Gene denotes CD38 Gene:952
1480 42292-42295 Gene denotes CD4 Gene:920
1481 41526-41534 Species denotes patients Tax:9606
1482 42030-42038 Species denotes patients Tax:9606
1483 42322-42330 Species denotes patients Tax:9606
1484 41470-41478 Disease denotes COVID-19 MESH:C000657245
1485 41517-41525 Disease denotes COVID-19 MESH:C000657245
1486 41634-41639 Disease denotes COVID MESH:C000657245
1487 41643-41648 Disease denotes death MESH:D003643
1488 41654-41659 Disease denotes COVID MESH:C000657245
1489 41707-41712 Disease denotes COVID MESH:C000657245
1492 42476-42483 Species denotes patient Tax:9606
1493 42467-42475 Disease denotes COVID-19 MESH:C000657245
1503 71154-71162 Species denotes med usin Tax:9606
1505 42840-42844 Chemical denotes UMAP
1506 42523-42531 Disease denotes COVID-19 MESH:C000657245
1507 42804-42813 Disease denotes mortality MESH:D003643
1509 61937-61945 Disease denotes COVID-19 MESH:C000657245
1521 44821-44824 Gene denotes CD8 Gene:925
1522 44833-44836 Gene denotes CD4 Gene:920
1523 44188-44195 Species denotes patient Tax:9606
1524 44674-44681 Species denotes patient Tax:9606
1525 44716-44724 Species denotes patients Tax:9606
1526 44903-44910 Species denotes patient Tax:9606
1527 45012-45020 Species denotes patients Tax:9606
1528 45131-45139 Species denotes patients Tax:9606
1529 45003-45011 Disease denotes COVID-19 MESH:C000657245
1541 45249-45257 Species denotes patients Tax:9606
1542 45769-45777 Species denotes patients Tax:9606
1543 46088-46095 Species denotes patient Tax:9606
1544 46117-46125 Species denotes patients Tax:9606
1545 46339-46347 Species denotes patients Tax:9606
1546 45563-45571 Disease denotes COVID-19 MESH:C000657245
1547 45754-45756 Disease denotes HD MESH:D006816
1548 45760-45768 Disease denotes COVID-19 MESH:C000657245
1549 46108-46116 Disease denotes COVID-19 MESH:C000657245
1550 46323-46325 Disease denotes HD MESH:D006816
1551 46330-46338 Disease denotes COVID-19 MESH:C000657245
1568 46703-46706 Gene denotes CD4 Gene:920
1569 46711-46714 Gene denotes CD8 Gene:925
1570 46937-46942 Gene denotes T-bet Gene:30009
1571 47007-47012 Gene denotes T-bet Gene:30009
1572 47033-47038 Gene denotes CD138 Gene:6382
1573 47084-47088 Gene denotes CD38 Gene:952
1574 47100-47103 Gene denotes CD4 Gene:920
1575 47108-47111 Gene denotes CD8 Gene:925
1576 47300-47305 Gene denotes T-bet Gene:30009
1577 47317-47320 Gene denotes CD8 Gene:925
1578 47379-47384 Gene denotes T-bet Gene:30009
1579 47396-47399 Gene denotes CD4 Gene:920
1580 47472-47477 Gene denotes Eomes Gene:8320
1581 47479-47482 Gene denotes CD8 Gene:925
1582 47486-47489 Gene denotes CD4 Gene:920
1583 46766-46768 Chemical denotes PB
1609 47835-47838 Gene denotes CD8 Gene:925
1610 47882-47887 Gene denotes T-bet Gene:30009
1611 47888-47894 Gene denotes CX3CR1 Gene:1524
1612 48107-48111 Gene denotes PD-1 Gene:100513601
1613 48112-48116 Gene denotes CD39 Gene:397298
1614 48200-48203 Gene denotes CD8 Gene:925
1615 48282-48285 Gene denotes CD4 Gene:920
1616 48351-48354 Gene denotes CD4 Gene:920
1617 48429-48432 Gene denotes CD4 Gene:920
1618 48471-48475 Gene denotes CD95 Gene:355
1619 48602-48605 Gene denotes CD4 Gene:920
1620 48714-48719 Gene denotes T-bet Gene:30009
1621 48720-48725 Gene denotes CD138 Gene:6382
1622 48797-48801 Gene denotes Tbet Gene:30009
1623 48802-48807 Gene denotes CD138 Gene:6382
1624 47748-47756 Species denotes patients Tax:9606
1625 47856-47863 Species denotes Cluster Tax:100569
1626 48061-48068 Species denotes Cluster Tax:100569
1627 48303-48310 Species denotes Cluster Tax:100569
1628 48485-48492 Species denotes Cluster Tax:100569
1629 48703-48710 Species denotes Cluster Tax:100569
1630 48731-48738 Species denotes Cluster Tax:100569
1631 48809-48816 Species denotes Cluster Tax:100569
1632 48653-48657 Chemical denotes cTfh
1633 47739-47747 Disease denotes COVID-19 MESH:C000657245
1645 49424-49428 Gene denotes IL-6 Gene:3569
1646 50141-50149 Species denotes patients Tax:9606
1647 50020-50030 Chemical denotes Remdesivir MESH:C000606551
1648 49387-49399 Disease denotes inflammation MESH:D007249
1649 49431-49443 Disease denotes co-infection MESH:D060085
1650 49445-49458 Disease denotes organ failure MESH:D009102
1651 49477-49497 Disease denotes acute kidney disease MESH:D058186
1652 49502-49521 Disease denotes renal insufficiency MESH:D051437
1653 50102-50111 Disease denotes mortality MESH:D003643
1654 50210-50218 Disease denotes COVID-19 MESH:C000657245
1655 50426-50434 Disease denotes COVID-19 MESH:C000657245
1677 50816-50819 Gene denotes CD4 Gene:920
1678 50844-50847 Gene denotes CD8 Gene:925
1679 50895-50898 Gene denotes CD8 Gene:925
1680 50912-50916 Gene denotes Tbet Gene:30009
1681 50992-50995 Gene denotes CD8 Gene:925
1682 51031-51034 Gene denotes CD4 Gene:920
1683 51194-51202 Species denotes patients Tax:9606
1684 51309-51317 Species denotes patients Tax:9606
1685 51520-51527 Species denotes patient Tax:9606
1686 51541-51550 Species denotes SARS-CoV2 Tax:2697049
1687 51579-51587 Species denotes patients Tax:9606
1688 51891-51899 Species denotes patients Tax:9606
1689 51989-51997 Species denotes patients Tax:9606
1690 52449-52456 Species denotes patient Tax:9606
1691 50666-50674 Disease denotes COVID-19 MESH:C000657245
1692 50695-50697 Disease denotes HD MESH:D006816
1693 51352-51354 Disease denotes HD MESH:D006816
1694 51551-51560 Disease denotes infection MESH:D007239
1695 51788-51796 Disease denotes COVID-19 MESH:C000657245
1696 51923-51931 Disease denotes COVID-19 MESH:C000657245
1697 52034-52042 Disease denotes COVID-19 MESH:C000657245
1716 52559-52568 Species denotes SARS-CoV2 Tax:2697049
1717 53078-53086 Species denotes patients Tax:9606
1718 53180-53188 Species denotes patients Tax:9606
1719 53258-53266 Species denotes patients Tax:9606
1720 53369-53377 Species denotes patients Tax:9606
1721 53478-53486 Species denotes patients Tax:9606
1722 53628-53636 Species denotes patients Tax:9606
1723 53767-53775 Species denotes patients Tax:9606
1724 53004-53013 Species denotes SARS-CoV2 Tax:2697049
1725 53194-53203 Species denotes SARS-CoV2 Tax:2697049
1726 52569-52578 Disease denotes infection MESH:D007239
1727 52737-52748 Disease denotes dysfunction MESH:D009461
1728 52944-52952 Disease denotes COVID-19 MESH:C000657245
1729 53167-53175 Disease denotes COVID-19 MESH:C000657245
1730 53456-53464 Disease denotes COVID-19 MESH:C000657245
1731 53598-53609 Disease denotes dysfunction MESH:D009461
1732 53613-53627 Disease denotes critically ill MESH:D016638
1733 53758-53766 Disease denotes COVID-19 MESH:C000657245
1763 54446-54449 Gene denotes CD4 Gene:920
1764 54943-54946 Gene denotes CD4 Gene:920
1765 55066-55069 Gene denotes CD8 Gene:925
1766 55097-55102 Gene denotes T-bet Gene:30009
1767 55137-55140 Gene denotes CD8 Gene:925
1768 55171-55174 Gene denotes CD4 Gene:920
1769 55444-55447 Gene denotes CD4 Gene:920
1770 54428-54431 Gene denotes CD8 Gene:925
1771 53846-53854 Species denotes patients Tax:9606
1772 53893-53901 Species denotes patients Tax:9606
1773 54192-54201 Species denotes SARS-CoV2 Tax:2697049
1774 54337-54345 Species denotes patients Tax:9606
1775 54402-54410 Species denotes patients Tax:9606
1776 54538-54546 Species denotes patients Tax:9606
1777 54639-54647 Species denotes patients Tax:9606
1778 54866-54874 Species denotes patients Tax:9606
1779 54890-54898 Species denotes patients Tax:9606
1780 55774-55782 Species denotes patients Tax:9606
1781 55794-55803 Species denotes SARS-CoV2 Tax:2697049
1782 55352-55356 Chemical denotes UMAP
1783 53824-53832 Disease denotes COVID-19 MESH:C000657245
1784 53884-53892 Disease denotes COVID-19 MESH:C000657245
1785 54064-54073 Disease denotes infection MESH:D007239
1786 54304-54312 Disease denotes COVID-19 MESH:C000657245
1787 54393-54401 Disease denotes COVID-19 MESH:C000657245
1788 54701-54709 Disease denotes COVID-19 MESH:C000657245
1789 54857-54865 Disease denotes COVID-19 MESH:C000657245
1790 55298-55307 Disease denotes infection MESH:D007239
1791 55804-55813 Disease denotes infection MESH:D007239
1813 56379-56384 Gene denotes CXCR5 Gene:643
1814 56498-56502 Gene denotes CD38 Gene:952
1815 56512-56515 Gene denotes CD4 Gene:920
1816 55892-55900 Species denotes patients Tax:9606
1817 55950-55955 Species denotes Ebola Tax:1570291
1818 56116-56124 Species denotes patients Tax:9606
1819 56688-56696 Species denotes patients Tax:9606
1820 56702-56711 Species denotes SARS-CoV2 Tax:2697049
1821 55874-55876 Chemical denotes PB
1822 55905-55907 Chemical denotes PB
1823 56013-56015 Chemical denotes PB
1824 56074-56078 Chemical denotes cTfh
1825 56152-56154 Chemical denotes PB
1826 56169-56173 Chemical denotes cTfh
1827 56325-56329 Chemical denotes cTfh
1828 56473-56477 Chemical denotes cTfh
1829 56770-56772 Chemical denotes PB
1830 56816-56820 Chemical denotes cTfh
1831 57063-57065 Chemical denotes PB
1832 55959-55975 Disease denotes Dengue infection MESH:D003715
1833 56107-56115 Disease denotes COVID-19 MESH:C000657245
1865 57427-57430 Gene denotes CD8 Gene:925
1866 57517-57521 Gene denotes CD95 Gene:355
1867 57565-57569 Gene denotes CD95 Gene:355
1868 57681-57685 Gene denotes CD38 Gene:952
1869 57694-57697 Gene denotes CD8 Gene:925
1870 57702-57705 Gene denotes CD4 Gene:920
1871 57898-57901 Gene denotes CD8 Gene:925
1872 57905-57908 Gene denotes CD4 Gene:920
1873 58030-58033 Gene denotes CD8 Gene:925
1874 58038-58041 Gene denotes CD4 Gene:920
1875 57343-57346 Gene denotes CD8 Gene:925
1876 57104-57112 Species denotes patients Tax:9606
1877 57285-57293 Species denotes patients Tax:9606
1878 57466-57471 Species denotes Ebola Tax:1570291
1879 57735-57743 Species denotes patients Tax:9606
1880 57832-57838 Species denotes humans Tax:9606
1881 58255-58263 Species denotes patients Tax:9606
1882 58372-58380 Species denotes patients Tax:9606
1883 58398-58406 Species denotes patients Tax:9606
1884 58614-58622 Species denotes patients Tax:9606
1885 58688-58696 Species denotes patients Tax:9606
1886 57955-57957 Chemical denotes PB
1887 57265-57276 Disease denotes lymphopenia MESH:D008231
1888 57300-57311 Disease denotes lymphopenia MESH:D008231
1889 57390-57401 Disease denotes lymphopenia MESH:D008231
1890 57472-57481 Disease denotes infection MESH:D007239
1891 57619-57627 Disease denotes COVID-19 MESH:C000657245
1892 57726-57734 Disease denotes COVID-19 MESH:C000657245
1893 57784-57800 Disease denotes viral infections MESH:D001102
1894 57875-57891 Disease denotes viral infections MESH:D001102
1895 58084-58092 Disease denotes COVID-19 MESH:C000657245
1911 59680-59683 Gene denotes CD4 Gene:920
1912 59757-59760 Gene denotes CD8 Gene:925
1913 59773-59778 Gene denotes T-bet Gene:30009
1914 59898-59901 Gene denotes CD8 Gene:925
1915 59924-59927 Gene denotes CD4 Gene:920
1916 59029-59036 Species denotes patient Tax:9606
1917 59266-59273 Species denotes patient Tax:9606
1918 60135-60143 Species denotes patients Tax:9606
1919 60199-60207 Species denotes patients Tax:9606
1920 60471-60479 Species denotes patients Tax:9606
1921 60606-60614 Species denotes patients Tax:9606
1922 59714-59718 Chemical denotes cTfh
1923 60284-60288 Chemical denotes UMAP
1924 59077-59085 Disease denotes COVID-19 MESH:C000657245
1925 60126-60134 Disease denotes COVID-19 MESH:C000657245
1931 60951-60959 Species denotes patients Tax:9606
1932 61310-61318 Species denotes patients Tax:9606
1933 61462-61470 Species denotes patients Tax:9606
1934 60668-60696 Disease denotes Respiratory viral infections
1935 60942-60950 Disease denotes COVID-19 MESH:C000657245
1937 61496-61504 Species denotes Patients Tax:9606
1955 61545-61553 Species denotes Patients Tax:9606
1956 61629-61638 Species denotes SARS-CoV2 Tax:2697049
1957 62968-62976 Species denotes patients Tax:9606
1958 63038-63046 Species denotes patients Tax:9606
1959 63273-63281 Species denotes patients Tax:9606
1960 63287-63299 Species denotes participants Tax:9606
1961 61748-61750 Disease denotes HD MESH:D006816
1962 61826-61834 Disease denotes COVID-19 MESH:C000657245
1963 61864-61867 Disease denotes HDs
1965 61994-62002 Disease denotes COVID-19 MESH:C000657245
1966 62098-62100 Disease denotes HD MESH:D006816
1967 62136-62149 Disease denotes word of mouth MESH:D000647
1968 62237-62245 Disease denotes COVID-19 MESH:C000657245
1969 62431-62435 Disease denotes ARDS MESH:D012128
1970 62870-62872 Disease denotes HD MESH:D006816
1971 62983-62988 Disease denotes COVID MESH:C000657245
1976 63945-63948 Gene denotes ACK Gene:10188
1977 63519-63526 Chemical denotes heparin MESH:D006493
1978 63665-63669 Chemical denotes RPMI
1979 63900-63904 Chemical denotes RPMI
1986 64168-64175 Species denotes patient Tax:9606
1987 64340-64351 Chemical denotes FACS buffer
1988 65239-65242 Chemical denotes PFA
1989 65293-65296 Chemical denotes PFA
1990 65388-65391 Chemical denotes PBS MESH:D007854
1991 65494-65513 Chemical denotes BD Brilliant Buffer
1993 65790-65804 CellLine denotes Cat#01-2222-42 CVCL:9J28
2033 66218-66222 Gene denotes CD28 Gene:940
2034 66223-66228 Gene denotes CD49d Gene:3676
2035 66732-66735 Gene denotes EGF Gene:1950
2036 66737-66742 Gene denotes FGF-2 Gene:2247
2037 66744-66751 Gene denotes Eotaxin Gene:6356
2038 66762-66767 Gene denotes G-CSF Gene:1440
2039 66769-66775 Gene denotes GM-CSF Gene:1437
2040 66777-66783 Gene denotes IFN-α2 Gene:3440
2041 66785-66790 Gene denotes IFN-γ Gene:3458
2042 66792-66797 Gene denotes IL-10 Gene:3586
2043 66819-66824 Gene denotes IL-13 Gene:3596
2044 66826-66831 Gene denotes IL-15 Gene:3600
2045 66833-66839 Gene denotes IL-17A Gene:3605
2046 66841-66847 Gene denotes IL-1Ra Gene:3557
2047 66849-66852 Gene denotes HGF Gene:3082
2048 66854-66859 Gene denotes IL-1β Gene:3552
2049 66861-66866 Gene denotes CXCL9 Gene:4283
2050 66867-66870 Gene denotes MIG Gene:4283
2051 66872-66876 Gene denotes IL-2 Gene:3558
2052 66878-66882 Gene denotes IL-4 Gene:3565
2053 66884-66888 Gene denotes IL-5 Gene:3567
2054 66890-66894 Gene denotes IL-6 Gene:3569
2055 66896-66900 Gene denotes IL-7 Gene:3574
2056 66902-66907 Gene denotes CXCL8 Gene:3576
2057 66908-66912 Gene denotes IL-8 Gene:3576
2058 66914-66920 Gene denotes CXCL10 Gene:3627
2059 66921-66926 Gene denotes IP-10 Gene:3627
2060 66928-66932 Gene denotes CCL2 Gene:6347
2061 66933-66938 Gene denotes MCP-1 Gene:6347
2062 66953-66957 Gene denotes CCL4 Gene:6351
2063 66958-66964 Gene denotes MIP-1β Gene:6351
2064 66966-66972 Gene denotes RANTES Gene:6352
2065 66974-66979 Gene denotes TNF-α Gene:7124
2066 66985-66989 Gene denotes VEGF Gene:7422
2067 65909-65917 Species denotes patients Tax:9606
2068 66643-66648 Species denotes human Tax:9606
2069 66212-66217 Species denotes human Tax:9606
2070 66088-66091 Chemical denotes PBS MESH:D007854
2071 66291-66295 CellLine denotes L293 CVCL:M775
2073 67315-67320 Species denotes minor Tax:53258
2075 67827-67831 Gene denotes CD28 Gene:940
2082 68090-68094 Gene denotes CD28 Gene:940
2083 68095-68100 Gene denotes CD49d Gene:3676
2084 68321-68325 Gene denotes IFNɣ Gene:3458
2085 68084-68089 Species denotes human Tax:9606
2086 67936-67939 Chemical denotes PBS MESH:D007854
2087 68163-68167 CellLine denotes L293 CVCL:M775
2089 68360-68367 Species denotes patient Tax:9606
2124 71856-71859 Gene denotes CD4 Gene:920
2125 72153-72158 Gene denotes CXCR5 Gene:643
2126 72160-72165 Gene denotes CD138 Gene:6382
2127 72167-72172 Gene denotes Eomes Gene:8320
2128 72174-72179 Gene denotes TCF-1 Gene:6932
2129 72181-72185 Gene denotes CD38 Gene:952
2130 72187-72191 Gene denotes CD95 Gene:355
2131 72193-72197 Gene denotes CCR7 Gene:1236
2132 72199-72203 Gene denotes CD21 Gene:1380
2133 72211-72215 Gene denotes CD27 Gene:939
2134 72217-72223 Gene denotes CX3CR1 Gene:1524
2135 72225-72229 Gene denotes CD39 Gene:953
2136 72231-72236 Gene denotes T-bet Gene:30009
2137 72246-72250 Gene denotes CD16 Gene:2214
2138 72252-72256 Gene denotes CD19 Gene:930
2139 72261-72265 Gene denotes CD20 Gene:54474
2140 72281-72284 Gene denotes CD4 Gene:920
2141 72289-72292 Gene denotes CD8 Gene:925
2142 72343-72346 Gene denotes PD1 Gene:6622
2143 72348-72353 Gene denotes CXCR5 Gene:643
2144 72355-72360 Gene denotes TCF-1 Gene:6932
2145 72362-72366 Gene denotes CD38 Gene:952
2146 72368-72372 Gene denotes CD95 Gene:355
2147 72374-72379 Gene denotes Eomes Gene:8320
2148 72381-72385 Gene denotes CCR7 Gene:1236
2149 72393-72397 Gene denotes CD16 Gene:2214
2150 72399-72403 Gene denotes CD27 Gene:939
2151 72405-72411 Gene denotes CX3CR1 Gene:1524
2152 72413-72417 Gene denotes CD39 Gene:953
2153 72419-72423 Gene denotes CD20 Gene:54474
2154 72425-72430 Gene denotes T-bet Gene:30009
2155 71883-71886 Gene denotes CD8 Gene:925
2159 72814-72819 Gene denotes Mover Gene:127262
2160 72905-72913 Species denotes patients Tax:9606
2161 72890-72898 Disease denotes COVID-19 MESH:C000657245
2163 74170-74174 Chemical denotes UMAP
2169 74258-74266 Species denotes patients Tax:9606
2170 74524-74531 Species denotes patient Tax:9606
2171 74860-74864 Chemical denotes UMAP
2172 74249-74257 Disease denotes COVID-19 MESH:C000657245
2173 74515-74523 Disease denotes COVID-19 MESH:C000657245
2182 75428-75431 Gene denotes CD4 Gene:920
2183 75465-75468 Gene denotes CD8 Gene:925
2184 75485-75489 Gene denotes CD38 Gene:952
2185 75509-75512 Gene denotes CD4 Gene:920
2186 75529-75533 Gene denotes CD38 Gene:952
2187 75553-75556 Gene denotes CD8 Gene:925
2188 75234-75242 Species denotes patients Tax:9606
2189 75225-75233 Disease denotes COVID-19 MESH:C000657245
2191 79408-79413 Disease denotes COVID MESH:C000657245
2194 79553-79558 Species denotes Julia Tax:33453
2195 79452-79459 Disease denotes Addison MESH:D000224

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 25-33 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 112-120 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 235-243 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 542-557 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T5 548-557 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 1029-1037 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 1044-1052 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 1092-1102 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T9 1147-1156 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T10 1162-1166 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 1173-1181 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 1393-1401 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T13 1422-1457 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T14 1428-1457 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T15 1459-1463 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T16 1525-1541 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T17 1664-1672 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 1834-1838 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T19 2049-2058 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T20 2337-2341 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 2852-2860 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 3099-3107 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 3108-3119 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T24 3191-3200 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T25 3229-3231 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T26 3327-3335 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 3635-3639 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T28 3645-3654 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T29 3832-3840 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T30 3965-3973 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 4095-4099 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T32 4524-4532 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 4752-4756 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T34 4762-4771 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 4912-4920 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 5027-5031 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T37 5037-5046 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T38 5048-5056 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T39 5326-5330 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T40 5336-5345 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T41 5365-5367 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T42 5411-5413 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T43 5494-5502 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T44 5635-5643 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T45 5943-5945 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T46 5966-5968 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T47 5975-5983 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 6043-6051 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T49 6076-6084 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T50 6213-6221 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T51 6531-6533 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T52 6603-6614 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T53 6762-6764 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T54 6776-6784 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T55 6855-6857 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T56 6927-6935 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T57 7002-7004 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T58 7009-7011 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T59 7142-7150 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T60 7253-7261 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T61 7375-7397 Disease denotes chronic kidney disease http://purl.obolibrary.org/obo/MONDO_0005300
T62 7383-7397 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T64 7553-7559 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T65 8092-8100 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T66 8121-8129 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T67 8350-8358 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T68 8763-8771 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 8946-8954 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 9295-9303 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T71 9794-9806 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T72 9857-9865 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 9966-9978 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T74 10088-10092 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T75 10098-10107 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T76 10166-10174 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T77 10185-10187 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T78 10193-10195 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T79 10351-10359 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T80 10381-10383 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T81 10387-10389 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T82 10420-10431 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T83 11046-11054 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 11311-11322 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T85 11330-11338 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 11732-11744 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T87 11859-11867 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T88 11996-12000 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T89 12006-12015 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T90 12211-12219 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T91 12338-12346 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 12367-12369 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T93 12384-12386 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T94 12490-12498 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 12532-12534 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T96 12539-12541 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T97 12564-12566 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T98 12571-12573 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T99 12653-12661 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T100 12712-12727 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T101 12718-12727 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T102 13286-13294 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T103 13316-13318 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T104 13532-13534 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T105 13554-13556 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T106 13651-13659 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 14094-14096 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T108 14224-14226 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T109 14246-14248 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T110 14255-14263 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T111 14691-14693 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T112 14720-14722 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T113 14734-14742 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T114 14813-14815 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T115 14896-14912 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T116 15131-15139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T117 15161-15163 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T118 15167-15169 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T119 15192-15200 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 15256-15258 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T121 15263-15265 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T122 15986-15994 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 16024-16033 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T124 16198-16206 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T125 16553-16555 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T126 16667-16675 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 17015-17023 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 17087-17095 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T129 17114-17116 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T130 17120-17122 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T131 17319-17322 Disease denotes FAS http://purl.obolibrary.org/obo/MONDO_0016011
T132 17370-17372 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T133 17407-17409 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T134 17569-17577 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T135 17834-17842 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T136 18089-18097 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T137 18264-18266 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T138 18330-18338 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T139 18450-18454 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T140 18460-18469 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 18787-18791 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T142 19262-19270 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T143 19292-19294 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T144 19445-19447 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T145 19460-19462 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T146 19502-19510 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 19613-19621 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 20054-20056 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T149 20060-20062 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T150 20567-20575 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T151 20665-20667 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T152 21320-21328 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T153 21387-21397 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T154 21611-21619 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T155 21891-21893 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T156 22030-22038 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T157 22134-22136 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T158 22272-22280 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T159 22402-22404 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T160 22406-22408 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T161 22414-22422 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T162 22847-22849 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T163 22876-22878 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T164 22890-22898 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T165 22969-22971 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T166 23205-23213 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T167 23214-23223 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T168 23262-23270 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T169 23271-23280 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T170 23619-23627 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T171 23649-23651 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T172 23656-23658 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T173 23946-23954 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T174 23976-23978 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T175 24136-24144 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T176 24172-24180 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 24635-24643 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T178 24657-24659 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T179 24712-24720 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T180 24763-24767 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T181 24849-24857 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T182 24931-24933 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T183 25391-25403 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T184 25461-25469 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T185 25532-25534 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T186 25737-25745 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T187 25894-25902 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T188 25916-25918 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T189 25969-25977 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T190 26265-26273 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T191 26373-26381 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T192 26382-26391 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T193 26535-26543 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T194 26602-26610 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T195 26624-26626 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T196 26630-26632 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T197 26828-26830 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T198 26895-26897 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T199 26975-26980 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T200 26984-26990 Disease denotes Dengue http://purl.obolibrary.org/obo/MONDO_0005502
T201 26991-27007 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T202 27033-27035 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T203 27125-27127 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T204 27151-27153 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T205 27158-27160 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T206 27242-27250 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T207 27371-27380 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T208 27388-27399 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T209 27437-27439 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T210 27477-27485 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T211 27507-27509 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T212 27513-27515 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T213 27582-27590 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T214 27790-27799 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T215 27801-27819 Disease denotes immune suppression http://purl.obolibrary.org/obo/MONDO_0007816
T216 27927-27929 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T217 28020-28028 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T218 28068-28080 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T219 28108-28116 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T220 28256-28258 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T221 28334-28336 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T222 28368-28370 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T223 28628-28630 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T224 28684-28686 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T225 28696-28700 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T226 28774-28778 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T227 29565-29567 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T228 29594-29596 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T229 29608-29616 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T230 29700-29702 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T231 29845-29861 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T232 29878-29880 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T233 29998-30000 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T234 30212-30214 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T235 30283-30285 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T236 30424-30426 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T237 30653-30661 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T238 30704-30708 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T239 30798-30800 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T240 30973-30975 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T241 31044-31046 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T242 31084-31088 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T243 31139-31151 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T244 31215-31219 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T245 31366-31370 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T246 31498-31500 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T247 31587-31589 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T248 31615-31619 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T249 31678-31680 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T250 31682-31684 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T251 31690-31698 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T252 31775-31783 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T253 31814-31816 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T254 31821-31823 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T255 31865-31873 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T256 31963-31965 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T257 31970-31972 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T258 32005-32007 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T259 32170-32172 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T260 32309-32317 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T261 32331-32333 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T262 32338-32340 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T263 32639-32647 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T264 32798-32806 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T265 32858-32860 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T266 32876-32878 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T267 32974-32983 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T268 33060-33062 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T269 33064-33066 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T270 33071-33079 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T271 33256-33258 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T272 33263-33265 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T273 33430-33438 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T274 33658-33666 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T275 33805-33807 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T276 33839-33847 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T277 33937-33945 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T278 34001-34003 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T279 34205-34213 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T280 34261-34263 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T281 34533-34541 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T282 34760-34768 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T283 34809-34817 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T284 35433-35441 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T285 35804-35812 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T286 36000-36002 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T287 36029-36031 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T288 36043-36051 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T289 36322-36330 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T290 37357-37365 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T291 38016-38018 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T292 38023-38025 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T293 38114-38123 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T294 38428-38443 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T295 38434-38443 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T296 38519-38535 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T297 38547-38555 Disease denotes smallpox http://purl.obolibrary.org/obo/MONDO_0004651
T298 38578-38586 Disease denotes vaccinia http://purl.obolibrary.org/obo/MONDO_0002595
T299 38615-38627 Disease denotes yellow fever http://purl.obolibrary.org/obo/MONDO_0020502
T300 38656-38665 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T301 38666-38681 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T302 38672-38681 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T303 38698-38711 Disease denotes HIV infection http://purl.obolibrary.org/obo/MONDO_0005109
T304 38702-38711 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T305 38762-38764 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T306 39270-39278 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T307 39658-39669 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T308 39943-39952 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T309 39992-39994 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T310 40105-40109 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T311 40474-40476 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T312 40491-40505 Disease denotes hyperlipidemia http://purl.obolibrary.org/obo/MONDO_0021187
T313 40552-40554 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T314 41011-41013 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T315 41197-41205 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T316 41383-41391 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T317 41470-41478 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T318 41517-41525 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T319 42467-42475 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T320 42523-42531 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T321 42647-42649 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T322 42977-42979 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T323 42999-43001 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T324 43008-43016 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T325 45003-45011 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T326 45563-45571 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T327 45754-45756 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T328 45760-45768 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T329 46108-46116 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T330 46289-46291 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T331 46323-46325 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T332 46330-46338 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T333 46766-46768 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T334 46944-46946 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T335 47040-47042 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T336 47739-47747 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T337 48727-48729 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T338 49387-49399 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T339 49434-49443 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T340 49483-49497 Disease denotes kidney disease http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T342 49502-49521 Disease denotes renal insufficiency http://purl.obolibrary.org/obo/MONDO_0001106
T343 50210-50218 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T344 50426-50434 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T345 50666-50674 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T346 50695-50697 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T347 50702-50704 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T348 50918-50920 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T349 51352-51354 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T350 51359-51361 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T351 51541-51545 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T352 51551-51560 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T353 51788-51796 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T354 51923-51931 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T355 52034-52042 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T356 52559-52563 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T357 52569-52578 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T358 52944-52952 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T359 53004-53008 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T360 53167-53175 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T361 53194-53198 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T362 53456-53464 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T363 53591-53609 Disease denotes immune dysfunction http://purl.obolibrary.org/obo/MONDO_0005046
T364 53758-53766 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T365 53824-53832 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T366 53884-53892 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T367 54064-54073 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T368 54192-54196 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T369 54304-54312 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T370 54393-54401 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T371 54490-54492 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T372 54701-54709 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T373 54857-54865 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T374 55104-55106 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T375 55203-55205 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T376 55298-55307 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T377 55794-55798 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T378 55804-55813 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T379 55874-55876 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T380 55905-55907 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T381 55950-55955 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T382 55959-55965 Disease denotes Dengue http://purl.obolibrary.org/obo/MONDO_0005502
T383 55966-55975 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T384 56013-56015 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T385 56107-56115 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T386 56152-56154 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T387 56702-56706 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T388 56770-56772 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T389 57063-57065 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T390 57265-57276 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T391 57300-57311 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T392 57390-57401 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T393 57466-57471 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T394 57472-57481 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T395 57619-57627 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T396 57726-57734 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T397 57784-57800 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T398 57875-57891 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T399 57955-57957 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T400 58064-58066 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T401 58084-58092 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T402 59077-59085 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T403 59780-59782 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T404 59964-59966 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T405 60126-60134 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T406 60680-60696 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T407 60942-60950 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T408 61629-61633 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T409 61748-61750 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T410 61826-61834 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T411 61937-61945 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T412 61956-61958 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T413 61994-62002 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T414 62098-62100 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T415 62105-62107 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T416 62237-62245 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T417 62431-62435 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T418 62870-62872 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T419 62877-62879 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T420 63534-63536 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T421 64340-64344 Disease denotes FACS http://purl.obolibrary.org/obo/MONDO_0018262
T422 64470-64474 Disease denotes FACS http://purl.obolibrary.org/obo/MONDO_0018262
T423 64763-64767 Disease denotes FACS http://purl.obolibrary.org/obo/MONDO_0018262
T424 64883-64887 Disease denotes FACS http://purl.obolibrary.org/obo/MONDO_0018262
T425 65341-65343 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T426 65473-65477 Disease denotes FACS http://purl.obolibrary.org/obo/MONDO_0018262
T427 65494-65496 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T428 65515-65517 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T429 65629-65631 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T430 65632-65636 Disease denotes FACS http://purl.obolibrary.org/obo/MONDO_0018262
T431 66305-66307 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T432 67283-67285 Disease denotes R2 http://purl.obolibrary.org/obo/MONDO_0019903
T433 68056-68058 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T434 68177-68179 Disease denotes BD http://purl.obolibrary.org/obo/MONDO_0007191
T435 72567-72570 Disease denotes SOM http://purl.obolibrary.org/obo/MONDO_0021203
T436 72653-72656 Disease denotes SOM http://purl.obolibrary.org/obo/MONDO_0021203
T437 72890-72898 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T438 74249-74257 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T439 74515-74523 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T440 75225-75233 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T441 75384-75386 Disease denotes PB http://purl.obolibrary.org/obo/MONDO_0019035
T442 75755-75757 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T443 75762-75764 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T444 76082-76090 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T445 76272-76274 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T447 76518-76524 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T448 76636-76642 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T449 76676-76682 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T450 76805-76807 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T452 76850-76852 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T454 76894-76896 Disease denotes NM http://purl.obolibrary.org/obo/MONDO_0008091|http://purl.obolibrary.org/obo/MONDO_0011603
T456 76972-76980 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T457 77060-77062 Disease denotes HD http://purl.obolibrary.org/obo/MONDO_0007739
T458 77067-77069 Disease denotes RD http://purl.obolibrary.org/obo/MONDO_0009973
T459 77138-77140 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T461 77208-77210 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T463 77374-77376 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T465 77426-77429 Disease denotes EMA http://purl.obolibrary.org/obo/MONDO_0009282
T466 77467-77475 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T467 77779-77781 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T469 77887-77889 Disease denotes DM http://purl.obolibrary.org/obo/MONDO_0005015|http://purl.obolibrary.org/obo/MONDO_0016367
T471 78418-78428 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T472 78433-78439 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T473 78545-78553 Disease denotes Pancreas http://purl.obolibrary.org/obo/MONDO_0021040

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 134-135 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 157-162 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T3 187-192 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T4 404-414 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T5 418-424 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T6 429-435 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T7 447-448 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 473-474 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T9 500-506 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T10 507-517 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T11 613-620 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T12 663-673 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T13 1062-1065 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T14 1576-1581 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T15 1861-1868 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T16 1944-1950 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T17 2025-2030 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18 2138-2143 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T19 2153-2156 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T20 2157-2163 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T21 2179-2184 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T22 2194-2197 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T23 2198-2204 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T24 2236-2239 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T25 2240-2246 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T26 2298-2299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 2453-2456 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T28 2457-2464 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T29 2472-2477 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T30 2472-2477 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T31 2531-2549 http://purl.obolibrary.org/obo/CL_0000815 denotes regulatory T cells
T32 2551-2555 http://purl.obolibrary.org/obo/CL_0000792 denotes Treg
T33 2563-2570 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T34 2574-2576 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T35 2579-2585 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T36 2664-2671 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T37 2672-2675 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T38 2767-2773 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T39 2774-2784 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T40 2831-2837 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T41 2838-2848 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T42 3053-3063 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T43 3121-3123 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T44 3581-3583 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T45 3710-3716 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T46 3901-3902 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 4260-4261 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 4573-4581 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T49 4775-4781 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T50 4829-4833 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T51 5068-5073 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T52 5068-5073 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T53 5236-5241 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T54 5236-5241 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T55 5365-5367 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T56 5546-5548 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T57 5673-5675 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T58 5744-5746 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T59 5744-5746 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T60 5876-5877 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T61 5966-5968 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T62 5995-5996 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T63 6074-6075 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 6330-6333 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T65 6334-6337 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T66 6338-6345 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T67 6375-6378 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T68 6379-6382 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T69 6762-6764 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T70 6845-6849 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T71 6949-6950 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 7009-7011 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T73 7027-7029 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T74 7231-7233 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T75 7231-7233 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T76 7383-7389 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T77 7383-7389 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T78 7383-7389 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T79 7402-7404 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T80 7410-7411 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T81 7443-7444 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T82 7465-7467 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T83 7538-7539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 7563-7564 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 7613-7615 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T86 7773-7774 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 8018-8026 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T88 8064-8067 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T89 8152-8153 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 8473-8474 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 8596-8598 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T92 8636-8638 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T93 8670-8675 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T94 8676-8680 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T95 8792-8793 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T96 8883-8884 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 9031-9039 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T98 10121-10155 http://purl.obolibrary.org/obo/CL_0000842 denotes peripheral blood mononuclear cells
T99 10121-10155 http://purl.obolibrary.org/obo/CL_2000001 denotes peripheral blood mononuclear cells
T100 10185-10187 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T101 10253-10260 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T102 10298-10304 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T103 10309-10312 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T104 10309-10312 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T105 10314-10320 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T106 10387-10389 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T107 10471-10472 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T108 10481-10488 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T109 10546-10547 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 10571-10572 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T111 10577-10578 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T112 10584-10590 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T113 10714-10715 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T114 10721-10727 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T115 10814-10817 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T116 10814-10817 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T117 10818-10825 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T118 10856-10859 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T119 10860-10867 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T120 10880-10883 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T121 10884-10891 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T122 11017-11020 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T123 11025-11028 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T124 11029-11035 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T125 11151-11154 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T126 11155-11162 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T127 11202-11205 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T128 11206-11213 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T129 11369-11370 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T130 11394-11397 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T131 11398-11405 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T132 11586-11589 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T133 11594-11597 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T134 11598-11605 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T135 11630-11653 http://purl.obolibrary.org/obo/CLO_0001869 denotes B, but not with B cells
T136 11677-11683 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T137 11811-11817 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T138 11890-11891 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T139 12035-12038 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T140 12039-12045 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T141 12046-12056 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T142 12060-12061 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T143 12173-12183 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T144 12367-12369 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T145 12392-12394 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T146 12478-12480 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T147 12532-12534 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T148 12564-12566 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T149 12599-12601 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T150 12732-12739 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T151 12743-12746 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T152 12747-12754 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T153 12766-12769 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T154 12770-12776 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T155 12828-12834 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T156 12836-12840 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T157 12842-12846 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T158 12857-12861 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T159 12895-12901 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T160 12902-12906 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T161 12907-12911 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T162 12936-12942 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T163 12943-12947 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T164 12948-12952 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T165 12978-12984 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T166 12985-12989 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T167 12990-12994 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T168 13003-13009 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T169 13010-13014 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T170 13015-13019 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T171 13022-13025 http://purl.obolibrary.org/obo/CLO_0002922 denotes EM2
T172 13028-13034 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T173 13035-13039 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T174 13040-13044 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T175 13047-13050 http://purl.obolibrary.org/obo/CLO_0002923 denotes EM3
T176 13064-13070 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T177 13071-13075 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T178 13076-13080 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T179 13093-13096 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T180 13097-13104 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T181 13116-13119 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T182 13120-13126 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T183 13169-13172 http://purl.obolibrary.org/obo/CLO_0002922 denotes EM2
T184 13198-13199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T185 13263-13268 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T186 13359-13367 http://purl.obolibrary.org/obo/CLO_0001757 denotes 1+ cells
T187 13399-13402 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T188 13493-13496 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T189 13497-13503 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T190 13532-13534 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T191 13598-13601 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T192 13602-13608 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T193 13628-13638 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T194 13692-13698 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T195 13718-13719 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T196 13792-13793 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T197 13858-13861 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T198 13862-13868 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T199 13897-13900 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T200 13901-13907 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T201 13964-13969 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T202 14011-14015 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T203 14017-14022 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T204 14145-14148 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T205 14149-14156 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T206 14192-14195 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T207 14196-14203 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T208 14246-14248 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T209 14394-14397 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T210 14398-14404 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T211 14551-14554 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T212 14555-14562 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T213 14720-14722 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T214 14803-14807 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T215 14938-14948 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T216 14952-14955 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T217 14956-14963 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T218 15016-15020 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T219 15033-15035 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T220 15037-15039 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T221 15052-15053 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T222 15100-15104 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T223 15116-15119 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T224 15120-15127 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T225 15167-15169 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T226 15217-15220 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T227 15221-15228 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T228 15263-15265 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T229 15298-15301 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T230 15302-15309 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T231 15370-15376 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T232 15377-15387 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T233 15421-15431 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T234 15495-15505 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T235 15509-15514 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T236 15524-15527 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T237 15528-15535 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T238 15542-15552 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T239 15591-15595 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T240 15661-15664 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T241 15665-15671 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T242 15743-15747 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T243 15756-15759 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T244 15760-15767 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T245 15821-15824 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T246 15825-15832 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T247 15866-15870 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T248 15879-15882 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T249 15883-15890 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T250 15929-15933 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T251 15957-15960 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T252 15961-15968 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T253 16176-16179 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T254 16180-16186 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T255 16361-16364 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T256 16365-16372 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T257 16424-16427 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T258 16428-16434 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T259 16435-16445 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T260 16503-16507 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T261 16516-16519 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T262 16520-16527 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T263 16597-16600 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T264 16601-16607 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T265 16608-16618 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T266 16623-16624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T267 16686-16687 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T268 16744-16747 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T269 16748-16754 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T270 16755-16765 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T271 16773-16778 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T272 16773-16778 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T273 16874-16876 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T274 16908-16909 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T275 16979-16982 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T276 16983-16990 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T277 17044-17045 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T278 17120-17122 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T279 17129-17132 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T280 17133-17140 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T281 17173-17177 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T282 17258-17268 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T283 17353-17356 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T284 17357-17364 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T285 17370-17372 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T286 17679-17682 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T287 17683-17689 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T288 17774-17779 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T289 17864-17870 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T290 17871-17875 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T291 17876-17880 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T292 18003-18007 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T293 18015-18019 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T294 18031-18040 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T295 18056-18061 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T296 18170-18176 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T297 18177-18181 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T298 18182-18186 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T299 18234-18236 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T300 18306-18309 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T301 18310-18316 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T302 18385-18394 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T303 18410-18413 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T304 18414-18421 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T305 18425-18426 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T306 18503-18506 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T307 18507-18513 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T308 18528-18538 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T309 18542-18545 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T310 18546-18552 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T311 18595-18598 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T312 18599-18605 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T313 18631-18634 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T314 18635-18642 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T315 18798-18800 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T316 18841-18847 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T317 18867-18869 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T318 18876-18885 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T319 18903-18907 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T320 18915-18924 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T321 19088-19089 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T322 19107-19124 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T323 19161-19164 http://purl.obolibrary.org/obo/CLO_0002922 denotes EM2
T324 19202-19211 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T325 19340-19341 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T326 19398-19407 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T327 19445-19447 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T328 19560-19564 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T329 19577-19594 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T330 19701-19704 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T331 19705-19711 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T332 19770-19774 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T333 19783-19788 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T334 19840-19843 http://purl.obolibrary.org/obo/CLO_0002922 denotes EM2
T335 19845-19848 http://purl.obolibrary.org/obo/CLO_0002923 denotes EM3
T336 19872-19873 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T337 19878-19879 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T338 19919-19929 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T339 20060-20062 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T340 20092-20096 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T341 20115-20132 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T342 20176-20193 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T343 20243-20260 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T344 20271-20275 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T345 20317-20326 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T346 20360-20370 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T347 20374-20377 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T348 20378-20385 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T349 20410-20420 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T350 20424-20427 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T351 20428-20435 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T352 20509-20512 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T353 20516-20519 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T354 20520-20526 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T355 20623-20626 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T356 20630-20633 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T357 20634-20641 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T358 20747-20756 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T359 20757-20760 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T360 20761-20768 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T361 20781-20784 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T362 20785-20792 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T363 20804-20805 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T364 20853-20863 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T365 20867-20870 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T366 20871-20878 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T367 20891-20894 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T368 20895-20902 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T369 20932-20936 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T370 20949-20965 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cell
T371 21052-21053 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T372 21075-21078 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T373 21079-21085 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T374 21086-21096 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T375 21152-21155 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T376 21156-21162 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T377 21163-21173 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T378 21240-21243 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T379 21244-21250 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T380 21299-21305 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T381 21306-21316 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T382 21354-21357 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T383 21489-21495 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T384 21523-21527 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T385 21574-21577 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T386 21578-21584 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T387 21585-21595 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T388 21599-21600 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T389 21654-21657 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T390 21658-21664 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T391 21675-21676 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T392 21741-21744 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T393 21745-21751 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T394 21762-21763 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T395 21780-21783 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T396 21784-21790 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T397 21838-21843 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T398 21943-21948 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T399 21958-21975 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T400 21993-21996 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T401 21997-22004 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T402 22075-22079 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T403 22081-22086 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T404 22187-22191 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T405 22193-22198 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T406 22214-22217 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T407 22235-22238 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T408 22239-22246 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T409 22332-22349 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T410 22379-22396 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T411 22406-22408 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T412 22547-22563 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cell
T413 22704-22721 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T414 22786-22787 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T415 22876-22878 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T416 22959-22963 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T417 23063-23066 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T418 23067-23073 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T419 23178-23181 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T420 23182-23188 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T421 23292-23293 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T422 23367-23371 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T423 23429-23432 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T424 23433-23440 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T425 23474-23477 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T426 23478-23484 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T427 23508-23509 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T428 23656-23658 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T429 23705-23709 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T430 23797-23800 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T431 23801-23808 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T432 23921-23926 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T433 24078-24087 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T434 24102-24105 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T435 24106-24113 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T436 24155-24156 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T437 24380-24384 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T438 24405-24411 http://purl.obolibrary.org/obo/CLO_0001044 denotes 11, 41
T439 24482-24488 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T440 24548-24554 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T441 24588-24591 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T442 24588-24591 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T443 24623-24624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T444 24729-24734 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T445 24729-24734 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T446 24793-24798 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T447 24793-24798 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T448 24871-24877 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T449 24978-24979 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T450 25148-25157 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T451 25158-25165 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T452 25279-25285 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T453 25660-25666 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T454 25720-25723 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T455 25724-25731 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T456 25877-25880 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T457 25881-25888 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T458 26057-26064 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T459 26251-26252 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T460 26283-26286 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T461 26477-26483 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T462 26492-26498 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T463 26567-26573 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T464 26624-26626 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T465 26673-26677 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T466 26708-26712 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T467 26722-26729 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T468 26795-26799 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T469 26805-26812 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T470 26817-26821 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T471 26822-26826 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T472 26870-26871 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T473 26876-26877 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T474 26930-26937 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T475 26991-26996 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T476 27158-27160 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T477 27217-27223 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T478 27299-27301 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4C
T479 27330-27331 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T480 27513-27515 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T481 27564-27570 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T482 27645-27652 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T483 27703-27720 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T484 27747-27753 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T485 27883-27884 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T486 27991-27997 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T487 28125-28131 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T488 28193-28199 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T489 28214-28215 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T490 28259-28265 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T491 28276-28277 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T492 28368-28375 http://purl.obolibrary.org/obo/CLO_0050940 denotes HD. (C)
T493 28437-28444 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T494 28529-28535 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T495 28567-28584 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T496 28635-28644 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T497 28750-28759 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T498 28842-28849 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T499 28880-28886 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T500 29112-29118 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T501 29244-29251 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T502 29328-29334 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T503 29441-29448 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T504 29513-29514 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T505 29594-29596 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T506 29634-29635 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T507 29690-29694 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T508 29925-29930 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T509 29925-29930 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T510 30035-30044 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T511 30069-30070 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T512 30098-30107 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T513 30131-30133 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T514 30135-30136 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T515 30183-30192 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T516 30330-30339 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T517 30363-30365 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T518 30367-30368 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T519 30441-30445 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T520 30463-30466 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T521 30467-30474 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T522 30494-30495 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T523 30516-30519 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T524 30520-30526 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T525 30553-30554 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T526 30601-30604 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T527 30605-30611 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T528 30922-30923 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T529 31016-31017 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T530 31264-31273 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T531 31330-31331 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T532 31393-31400 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T533 31428-31430 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T534 31665-31672 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T535 31682-31684 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T536 31731-31732 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T537 31753-31759 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T538 31814-31816 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T539 31882-31888 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T540 31950-31957 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T541 31970-31972 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T542 32073-32077 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T543 32079-32083 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T544 32153-32157 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T545 32158-32162 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T546 32338-32340 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T547 32373-32379 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T548 32427-32429 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T549 32760-32766 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T550 32876-32878 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T551 32993-32999 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T552 33064-33066 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T553 33263-33265 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T554 33289-33296 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T555 33302-33306 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T556 33335-33339 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T557 33535-33542 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T558 33735-33742 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T559 33783-33787 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T560 33788-33792 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T561 33924-33931 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T562 34089-34095 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T563 34154-34160 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T564 34285-34291 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T565 34315-34316 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T566 34324-34330 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T567 34405-34411 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T568 34515-34521 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T569 34594-34603 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T570 34604-34610 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T571 34625-34626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T572 34678-34684 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T573 34685-34691 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T574 34730-34734 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T575 34777-34778 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T576 34922-34925 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T577 34926-34932 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T578 34934-34937 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T579 34938-34944 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T580 34950-34956 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T581 35192-35195 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T582 35196-35202 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T583 35204-35207 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T584 35208-35214 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T585 35220-35226 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T586 35315-35318 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T587 35319-35326 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T588 35376-35380 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T589 35389-35392 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T590 35393-35399 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T591 35497-35498 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T592 35529-35532 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T593 35533-35539 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T594 35544-35550 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T595 35551-35561 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T596 35675-35676 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T597 35715-35718 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T598 35719-35726 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T599 35732-35749 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T600 35755-35762 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T601 35793-35798 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T602 35878-35879 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T603 35898-35902 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T604 35904-35907 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T605 35908-35915 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T606 35938-35942 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T607 35944-35947 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T608 35948-35955 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T609 36029-36031 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T610 36177-36181 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T611 36290-36294 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T612 36296-36299 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T613 36300-36307 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T614 36712-36715 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T615 36720-36723 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T616 36724-36730 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T617 36734-36740 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T618 36810-36814 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T619 36836-36839 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T620 36870-36873 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T621 36874-36881 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T622 37172-37173 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T623 37398-37402 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T624 37538-37542 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T625 37548-37565 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T626 37612-37617 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T627 37690-37693 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T628 37694-37701 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T629 37789-37792 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T630 37793-37799 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T631 37947-37950 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T632 37951-37958 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T633 38023-38025 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T634 38065-38066 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T635 38077-38080 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T636 38081-38087 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T637 38125-38126 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T638 38167-38171 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T639 38183-38186 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T640 38231-38232 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T641 38346-38355 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T642 38373-38376 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T643 38381-38384 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T644 38385-38391 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T645 38486-38489 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T646 38494-38497 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T647 38498-38505 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T648 38587-38592 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T649 38640-38643 http://purl.obolibrary.org/obo/CLO_0001134 denotes 17D
T650 38645-38647 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T651 38666-38671 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T652 38713-38715 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T653 38800-38807 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T654 38883-38889 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T655 38893-38899 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T656 38900-38910 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T657 39060-39070 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T658 39132-39138 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T659 39139-39149 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T660 39222-39228 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T661 39471-39474 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T662 39479-39482 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T663 39483-39490 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T664 39499-39503 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T665 39516-39525 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T666 39613-39614 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T667 39636-39642 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T668 39643-39653 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T669 39697-39700 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T670 39705-39708 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T671 39716-39720 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T672 39722-39729 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T673 39798-39802 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T674 39804-39807 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T675 39808-39814 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T676 39900-39909 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T677 40029-40032 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T678 40037-40040 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T679 40041-40048 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T680 40630-40634 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T681 40643-40646 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T682 40647-40654 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T683 40826-40830 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T684 40839-40842 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T685 40843-40850 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T686 41067-41073 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T687 41178-41184 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T688 41335-41336 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T689 41341-41347 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T690 41793-41799 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T691 41927-41930 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T692 41935-41938 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T693 41939-41946 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T694 41953-41954 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T695 41973-41976 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T696 41977-41984 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T697 42110-42116 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T698 42121-42127 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T699 42206-42207 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T700 42235-42239 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T701 42241-42244 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T702 42245-42252 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T703 42286-42290 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T704 42292-42295 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T705 42296-42303 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T706 42498-42499 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T707 42552-42553 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T708 42637-42641 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T709 42999-43001 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T710 43494-43500 http://purl.obolibrary.org/obo/CLO_0054111 denotes 1 (C1)
T711 43518-43520 http://purl.obolibrary.org/obo/CLO_0002105 denotes C2
T712 43518-43520 http://purl.obolibrary.org/obo/CLO_0051742 denotes C2
T713 44474-44480 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T714 44775-44781 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T715 44821-44824 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T716 44825-44831 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T717 44833-44836 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T718 44837-44843 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T719 44848-44854 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T720 44882-44883 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T721 45060-45067 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T722 45092-45102 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T723 45308-45309 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T724 45349-45355 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T725 45515-45517 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T726 45730-45731 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T727 46212-46213 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T728 46289-46291 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T729 46617-46619 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T730 46703-46706 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T731 46711-46714 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T732 46715-46722 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T733 46749-46754 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T734 46830-46836 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T735 46924-46925 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T736 46926-46932 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T737 46966-46968 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T738 47021-47028 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T739 47067-47076 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activated
T740 47084-47088 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T741 47100-47103 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T742 47108-47111 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T743 47112-47119 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T744 47278-47279 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T745 47317-47320 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T746 47321-47328 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T747 47390-47407 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T748 47460-47462 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T749 47479-47482 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T750 47486-47489 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T751 47490-47497 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T752 47599-47601 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T753 47710-47720 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T754 47835-47838 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T755 47839-47846 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T756 47864-47866 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T757 47932-47937 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T758 48082-48091 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T759 48118-48123 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T760 48200-48203 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T761 48204-48211 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T762 48282-48285 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T763 48286-48293 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T764 48326-48335 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T765 48351-48354 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T766 48355-48362 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T767 48410-48411 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T768 48419-48428 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T769 48429-48432 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T770 48433-48439 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T771 48602-48605 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T772 48606-48612 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T773 48682-48689 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T774 49030-49032 http://purl.obolibrary.org/obo/CLO_0008935 denotes S9
T775 49034-49035 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T776 49445-49450 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T777 49483-49489 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T778 49483-49489 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T779 49483-49489 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T780 50317-50318 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T781 50477-50478 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T782 50600-50607 http://purl.obolibrary.org/obo/SO_0000418 denotes signals
T783 50702-50704 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T784 50806-50815 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T785 50816-50819 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T786 50820-50827 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T787 50844-50847 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T788 50859-50869 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T789 50895-50898 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T790 50899-50906 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T791 50992-50995 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T792 50996-51003 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T793 51031-51034 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T794 51035-51041 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T795 51042-51052 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T796 51057-51060 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T797 51092-51099 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T798 51182-51183 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T799 51216-51226 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T800 51236-51242 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T801 51359-51361 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T802 51371-51380 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T803 51392-51393 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T804 51398-51404 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T805 51598-51599 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T806 51751-51752 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T807 52540-52546 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T808 52716-52722 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T809 52782-52787 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T810 52839-52841 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T811 52969-52974 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T812 52984-52990 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T813 53133-53139 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T814 53438-53439 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T815 53571-53572 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T816 53670-53677 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T817 53867-53868 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T818 53990-53991 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T819 53996-54002 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T820 54282-54283 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T821 54428-54431 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T822 54432-54438 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T823 54446-54449 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T824 54450-54456 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T825 54457-54467 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T826 54511-54512 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T827 54671-54672 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T828 54677-54683 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T829 54911-54921 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T830 54943-54946 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T831 54947-54954 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T832 55000-55010 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T833 55043-55052 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T834 55066-55069 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T835 55070-55077 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T836 55082-55083 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T837 55137-55140 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T838 55141-55147 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T839 55171-55174 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T840 55175-55181 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T841 55217-55224 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T842 55320-55321 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T843 55340-55350 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T844 55388-55394 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T845 55395-55405 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T846 55429-55430 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T847 55444-55447 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T848 55448-55454 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T849 55455-55465 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T850 55815-55816 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T851 55977-55979 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T852 56007-56012 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T853 56007-56012 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T854 56058-56063 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T855 56058-56063 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T856 56064-56073 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T857 56159-56168 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T858 56227-56237 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T859 56270-56276 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T860 56289-56295 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T861 56315-56324 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T862 56344-56349 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T863 56344-56349 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T864 56487-56496 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T865 56498-56502 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T866 56512-56515 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T867 56516-56523 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T868 56535-56536 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T869 56555-56561 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T870 56625-56626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T871 56938-56943 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T872 57077-57078 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T873 57131-57137 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T874 57138-57148 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T875 57215-57216 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T876 57217-57227 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T877 57343-57346 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T878 57347-57354 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T879 57427-57430 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T880 57431-57438 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T881 57447-57448 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T882 57590-57599 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T883 57600-57606 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T884 57681-57685 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T885 57694-57697 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T886 57702-57705 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T887 57706-57712 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T888 57832-57838 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T889 57898-57901 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T890 57905-57908 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T891 57909-57915 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T892 57972-57977 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T893 57972-57977 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T894 58030-58033 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T895 58038-58041 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T896 58042-58048 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T897 58049-58059 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T898 58110-58111 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T899 58196-58197 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T900 58468-58482 http://purl.obolibrary.org/obo/CL_0001034 denotes cells in vitro
T901 58528-58538 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T902 58562-58567 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T903 58569-58570 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T904 58721-58727 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T905 59680-59683 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T906 59684-59690 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T907 59691-59701 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T908 59757-59760 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T909 59761-59768 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T910 59898-59901 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T911 59902-59909 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T912 59924-59927 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T913 59928-59934 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T914 59935-59945 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T915 59978-59985 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T916 60070-60080 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T917 60151-60152 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T918 60237-60238 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T919 60262-60268 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T920 60387-60397 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T921 60720-60721 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T922 60783-60788 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T923 61172-61173 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T924 61245-61246 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T925 61618-61619 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T926 61643-61647 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T927 61956-61958 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T928 61977-61978 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T929 62007-62011 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T930 62105-62107 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T931 62144-62149 http://www.ebi.ac.uk/efo/EFO_0000825 denotes mouth
T932 62175-62176 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T933 62274-62279 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T934 62274-62279 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T935 62475-62481 http://purl.obolibrary.org/obo/CLO_0001929 denotes Berlin
T936 62578-62583 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T937 62852-62857 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T938 62852-62857 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T939 62877-62879 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T940 62890-62891 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T941 63487-63492 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T942 63487-63492 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T943 63527-63532 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tubes
T944 63551-63556 http://purl.obolibrary.org/obo/UBERON_0000025 denotes Tubes
T945 63591-63597 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T946 63629-63640 http://purl.obolibrary.org/obo/UBERON_0000178 denotes whole blood
T947 63629-63640 http://www.ebi.ac.uk/efo/EFO_0000296 denotes whole blood
T948 63653-63656 http://purl.obolibrary.org/obo/CLO_0053733 denotes 1:1
T949 63698-63699 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T950 63708-63712 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T951 63818-63823 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tubes
T952 64026-64027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T953 64426-64428 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T954 64455-64456 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T955 64726-64727 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T956 64736-64738 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T957 65123-65126 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4°C
T958 65619-65620 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T959 66055-66058 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T960 66055-66058 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T961 66095-66098 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4°C
T962 66124-66129 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T963 66156-66166 http://purl.obolibrary.org/obo/CLO_0001040 denotes at 1 × 105
T964 66212-66217 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T965 66280-66283 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T966 66280-66283 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T967 66441-66447 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T968 66634-66635 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T969 66643-66648 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T970 66762-66767 http://purl.obolibrary.org/obo/PR_000005932 denotes G-CSF
T971 66849-66852 http://purl.obolibrary.org/obo/CLO_0003740 denotes HGF
T972 66872-66876 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T973 66908-66912 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T974 67024-67025 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T975 67045-67055 http://purl.obolibrary.org/obo/OBI_0000968 denotes instrument
T976 67274-67277 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T977 67278-67279 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T978 67528-67534 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T979 67556-67561 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T980 67727-67729 http://purl.obolibrary.org/obo/CLO_0008954 denotes SC
T981 67744-67750 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T982 67823-67826 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T983 67823-67826 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T984 67903-67906 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T985 67903-67906 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T986 67943-67946 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4°C
T987 67972-67977 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T988 68004-68014 http://purl.obolibrary.org/obo/CLO_0001040 denotes at 1 × 105
T989 68084-68089 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T990 68152-68155 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T991 68152-68155 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T992 68437-68441 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T993 68553-68554 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T994 68597-68598 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T995 68642-68643 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T996 68665-68666 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T997 68801-68802 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T998 68893-68894 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T999 68973-68974 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1000 69085-69090 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T1001 69148-69153 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T1002 69207-69208 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1003 69349-69354 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T1004 69465-69466 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1005 69656-69657 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1006 70072-70077 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T1007 70268-70269 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1008 70451-70456 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T1009 70574-70578 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T1010 70623-70627 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T1011 70723-70727 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T1012 70745-70752 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T1013 70839-70844 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1014 70839-70844 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1015 70935-70940 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T1016 70973-70974 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1017 71097-71104 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T1018 71239-71244 http://purl.obolibrary.org/obo/UBERON_0000982 denotes Joint
T1019 71239-71244 http://purl.obolibrary.org/obo/UBERON_0004905 denotes Joint
T1020 71341-71348 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T1021 71837-71844 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T1022 71850-71867 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T1023 71883-71886 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T1024 71887-71894 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1025 71979-71984 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1026 72027-72028 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1027 72051-72052 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1028 72071-72078 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T1029 72140-72146 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T1030 72181-72185 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T1031 72193-72197 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T1032 72211-72215 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T1033 72252-72256 http://purl.obolibrary.org/obo/CLO_0053432 denotes CD19
T1034 72281-72284 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T1035 72289-72292 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T1036 72293-72300 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1037 72335-72341 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T1038 72362-72366 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T1039 72381-72385 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T1040 72399-72403 http://purl.obolibrary.org/obo/PR_000001963 denotes CD27
T1041 72527-72531 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1042 72540-72541 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1043 72551-72561 http://purl.obolibrary.org/obo/OBI_0000245 denotes organizing
T1044 72658-72661 http://purl.obolibrary.org/obo/CLO_0001196 denotes 225
T1045 72717-72724 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T1046 72729-72736 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1047 72781-72787 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T1048 72865-72871 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T1049 73381-73382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1050 73450-73451 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1051 74027-74028 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1052 74102-74106 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T1053 74191-74192 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1054 74289-74290 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1055 74326-74327 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1056 74935-74936 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1057 75023-75024 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1058 75395-75402 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T1059 75422-75439 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T1060 75465-75468 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T1061 75469-75476 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1062 75485-75489 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T1063 75503-75520 http://purl.obolibrary.org/obo/CL_0000895 denotes naïve CD4 T cells
T1064 75529-75533 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T1065 75553-75556 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T1066 75557-75564 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1067 75648-75653 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T1068 75648-75653 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T1069 75762-75764 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T1070 76516-76517 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1071 77019-77021 http://purl.obolibrary.org/obo/CLO_0008246 denotes OK
T1072 77067-77069 http://purl.obolibrary.org/obo/CLO_0008770 denotes RD
T1073 77165-77167 http://purl.obolibrary.org/obo/CLO_0001547 denotes AP
T1074 77169-77171 http://purl.obolibrary.org/obo/CLO_0052676 denotes FC
T1075 77387-77389 http://purl.obolibrary.org/obo/CLO_0052676 denotes FC
T1076 77440-77443 http://purl.obolibrary.org/obo/CLO_0002599 denotes CPA
T1077 77484-77490 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T1078 77855-77857 http://purl.obolibrary.org/obo/PR_000010213 denotes MB
T1079 78001-78004 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1080 78141-78142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1081 78203-78206 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T1082 78207-78208 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1083 78303-78304 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1084 78539-78544 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T1085 78545-78553 http://purl.obolibrary.org/obo/UBERON_0001264 denotes Pancreas
T1086 78653-78659 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T1087 78729-78746 http://purl.obolibrary.org/obo/CL_0000895 denotes Naive CD4 T cells
T1088 78817-78820 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T1089 78821-78828 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T1090 78917-78918 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1091 79119-79120 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1092 79310-79311 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1093 79642-79643 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T1094 79871-79874 http://purl.obolibrary.org/obo/CL_0000990 denotes DC1
T1095 79881-79883 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1096 79897-79899 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1844-1851 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T2 1918-1926 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T3 1935-1937 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T4 1952-1960 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T5 2427-2429 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T7 2436-2438 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T8 3229-3231 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T10 5365-5367 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T11 5411-5413 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T12 5744-5746 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T13 5750-5752 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T14 5943-5945 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T15 5966-5968 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T16 6102-6107 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T17 6531-6533 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T18 6747-6752 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T19 6762-6764 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T20 7002-7004 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T21 7009-7011 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T22 7231-7233 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T23 7651-7669 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T24 7686-7694 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T25 7709-7719 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T26 8197-8204 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T27 8517-8519 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T29 9572-9574 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T31 10185-10187 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T32 10193-10195 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T33 10381-10383 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T34 10387-10389 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T35 11507-11509 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T36 11660-11662 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T37 11790-11792 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T38 12273-12276 Chemical denotes PCA http://purl.obolibrary.org/obo/CHEBI_36751|http://purl.obolibrary.org/obo/CHEBI_62248
T40 12367-12369 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T41 12384-12386 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T42 12478-12480 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T43 12532-12534 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T44 12539-12541 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T45 12545-12548 Chemical denotes PCA http://purl.obolibrary.org/obo/CHEBI_36751|http://purl.obolibrary.org/obo/CHEBI_62248
T47 12564-12566 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T48 12571-12573 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T49 12961-12969 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T50 13316-13318 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T51 13356-13358 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T52 13532-13534 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T53 13554-13556 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T54 13751-13754 Chemical denotes PCA http://purl.obolibrary.org/obo/CHEBI_36751|http://purl.obolibrary.org/obo/CHEBI_62248
T56 13949-13952 Chemical denotes PD1 http://purl.obolibrary.org/obo/CHEBI_138655
T57 14008-14010 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T58 14094-14096 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T59 14217-14222 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T60 14224-14226 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T61 14239-14244 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T62 14246-14248 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T63 14340-14347 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T64 14684-14689 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T65 14691-14693 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T66 14713-14718 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T67 14720-14722 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T68 15029-15031 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T69 15097-15099 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T70 15161-15163 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T71 15167-15169 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T72 15256-15258 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T73 15263-15265 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T74 15480-15487 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T75 15584-15586 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T76 15752-15754 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T77 15875-15877 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T78 15938-15940 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T79 16128-16136 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T80 16389-16391 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T82 16512-16514 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T83 16553-16555 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T84 17114-17116 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T85 17120-17122 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T86 17183-17185 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T87 17203-17206 Chemical denotes PD1 http://purl.obolibrary.org/obo/CHEBI_138655
T88 17319-17322 Chemical denotes FAS http://purl.obolibrary.org/obo/CHEBI_76181
T89 17370-17372 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T90 17407-17409 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T91 18012-18014 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T92 18025-18027 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T93 18264-18266 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T94 18661-18669 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T95 18848-18851 Chemical denotes PD1 http://purl.obolibrary.org/obo/CHEBI_138655
T96 18986-18993 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T97 19292-19294 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T98 19445-19447 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T99 19460-19462 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T100 19529-19534 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T101 19569-19571 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T102 19779-19781 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T103 19807-19815 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T104 19836-19838 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T105 19868-19870 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T106 19978-19981 Chemical denotes PD1 http://purl.obolibrary.org/obo/CHEBI_138655
T107 20054-20056 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T108 20060-20062 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T109 20075-20077 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638
T110 20105-20107 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T111 20280-20282 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T112 20665-20667 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
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T194 28684-28686 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T207 30212-30214 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T212 30424-30426 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T218 30973-30975 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T220 31044-31046 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T227 31587-31589 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T252 34261-34263 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T278 40474-40476 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T35800 54490-54492 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T60468 55104-55106 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T50303 55874-55876 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T61838 55905-55907 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T94843 56013-56015 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T31632 56152-56154 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T39 58064-58066 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T88670 59780-59782 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T44023 59889-59897 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T55913 59964-59966 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
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T83633 64204-64210 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T45213 64233-64235 Chemical denotes S8 http://purl.obolibrary.org/obo/CHEBI_29385
T6104 64345-64351 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T38115 64475-64481 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T13410 64768-64774 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T22243 64888-64894 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T74159 64991-64997 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T86249 65239-65242 Chemical denotes PFA http://purl.obolibrary.org/obo/CHEBI_53371|http://purl.obolibrary.org/obo/CHEBI_60594
T30642 65293-65296 Chemical denotes PFA http://purl.obolibrary.org/obo/CHEBI_53371|http://purl.obolibrary.org/obo/CHEBI_60594
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T45026 65701-65704 Chemical denotes RFP http://purl.obolibrary.org/obo/CHEBI_28077
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T65282 66769-66771 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T7701 66792-66794 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T70736 66799-66801 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T87965 66809-66811 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T48479 66819-66821 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T16150 66826-66828 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T29560 66833-66835 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T21327 66841-66843 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T47948 66854-66856 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T94087 66861-66866 Chemical denotes CXCL9 http://purl.obolibrary.org/obo/CHEBI_138154
T89357 66872-66874 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T78875 66878-66880 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T30910 66884-66886 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T92516 66890-66892 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T24109 66896-66898 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T31035 66908-66910 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T89429 66914-66920 Chemical denotes CXCL10 http://purl.obolibrary.org/obo/CHEBI_138157
T61718 66921-66926 Chemical denotes IP-10 http://purl.obolibrary.org/obo/CHEBI_138157
T96412 66921-66923 Chemical denotes IP http://purl.obolibrary.org/obo/CHEBI_74076
T85413 66933-66936 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T84878 70270-70277 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T47968 72242-72244 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T69235 72343-72346 Chemical denotes PD1 http://purl.obolibrary.org/obo/CHEBI_138655
T22932 72440-72442 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T12732 72754-72759 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T50300 74322-74324 Chemical denotes S8 http://purl.obolibrary.org/obo/CHEBI_29385
T64153 74393-74397 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T67801 74466-74470 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T2551 74997-75001 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T84888 75384-75386 Chemical denotes PB http://purl.obolibrary.org/obo/CHEBI_53319|http://purl.obolibrary.org/obo/CHEBI_60686
T53019 75482-75484 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T74745 75526-75528 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T64579 75755-75757 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T34479 75762-75764 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T69904 76272-76274 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T712 76348-76351 Chemical denotes DAO http://purl.obolibrary.org/obo/CHEBI_30805
T40913 76582-76584 Chemical denotes AH http://purl.obolibrary.org/obo/CHEBI_73771
T41500 76805-76807 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T84118 76850-76852 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T12270 76894-76896 Chemical denotes NM http://purl.obolibrary.org/obo/CHEBI_141423
T86921 77060-77062 Chemical denotes HD http://purl.obolibrary.org/obo/CHEBI_73925
T35838 77067-77069 Chemical denotes RD http://purl.obolibrary.org/obo/CHEBI_73812
T5332 77079-77081 Chemical denotes KD http://purl.obolibrary.org/obo/CHEBI_73601
T68846 77138-77140 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T19371 77157-77159 Chemical denotes NH http://purl.obolibrary.org/obo/CHEBI_29339|http://purl.obolibrary.org/obo/CHEBI_73424
T73697 77165-77167 Chemical denotes AP http://purl.obolibrary.org/obo/CHEBI_28971|http://purl.obolibrary.org/obo/CHEBI_73393|http://purl.obolibrary.org/obo/CHEBI_81686
T136 77208-77210 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T21111 77374-77376 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T138 77421-77424 Chemical denotes ECG http://purl.obolibrary.org/obo/CHEBI_70255
T5355 77436-77438 Chemical denotes SG http://purl.obolibrary.org/obo/CHEBI_74814
T140 77659-77662 Chemical denotes DAO http://purl.obolibrary.org/obo/CHEBI_30805
T81966 77664-77666 Chemical denotes SM http://purl.obolibrary.org/obo/CHEBI_17076|http://purl.obolibrary.org/obo/CHEBI_74817
T10321 77717-77720 Chemical denotes DAO http://purl.obolibrary.org/obo/CHEBI_30805
T24442 77726-77728 Chemical denotes SM http://purl.obolibrary.org/obo/CHEBI_17076|http://purl.obolibrary.org/obo/CHEBI_74817
T96953 77779-77781 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T63835 77801-77804 Chemical denotes DAO http://purl.obolibrary.org/obo/CHEBI_30805
T952 77833-77835 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801
T38534 77887-77889 Chemical denotes DM http://purl.obolibrary.org/obo/CHEBI_141426
T22801 78243-78245 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T154 78395-78397 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T41990 78967-78969 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T38197 79781-79783 Chemical denotes PA http://purl.obolibrary.org/obo/CHEBI_30745|http://purl.obolibrary.org/obo/CHEBI_30768|http://purl.obolibrary.org/obo/CHEBI_74753|http://purl.obolibrary.org/obo/CHEBI_7959|http://purl.obolibrary.org/obo/CHEBI_8429
T57916 79903-79905 Chemical denotes S8 http://purl.obolibrary.org/obo/CHEBI_29385

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 163-179 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T2 500-517 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T3 502-517 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T4 542-557 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T5 652-673 http://purl.obolibrary.org/obo/GO_0046649 denotes lymphocyte activation
T6 1525-1541 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T7 1613-1628 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T8 1723-1738 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T9 1905-1911 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T10 1927-1933 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T11 1961-1967 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T12 2062-2074 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T13 2361-2383 http://purl.obolibrary.org/obo/GO_0006954 denotes Inflammatory responses
T14 2767-2784 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T15 2769-2784 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T16 2831-2848 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T17 2833-2848 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T18 3311-3323 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T19 3974-3986 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T20 4075-4091 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T21 4134-4149 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T22 4339-4354 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T23 4414-4430 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T24 4652-4667 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T25 9794-9806 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T26 9966-9978 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T27 10062-10078 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T28 11732-11744 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T29 12039-12056 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T30 12041-12056 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T31 12162-12183 http://purl.obolibrary.org/obo/GO_0046649 denotes lymphocyte activation
T32 12712-12727 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T33 12928-12934 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T34 12970-12976 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T35 13510-13516 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T36 14896-14912 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T37 15370-15387 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T38 15372-15387 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T39 16428-16445 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T40 16430-16445 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T41 16601-16618 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T42 16603-16618 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T43 16748-16765 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T44 16750-16765 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T45 18670-18676 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T46 18696-18702 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T47 19816-19822 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T48 21079-21096 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T49 21081-21096 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T50 21156-21173 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T51 21158-21173 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T52 21299-21316 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T53 21301-21316 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T54 21578-21595 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T55 21580-21595 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T56 23067-23089 http://purl.obolibrary.org/obo/GO_0030217 denotes T cell differentiation
T57 23069-23089 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T58 24209-24230 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T59 24366-24372 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1RA
T60 25026-25032 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1RA
T61 25391-25403 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T62 25520-25526 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1RA
T63 26470-26476 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T64 26715-26721 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T65 28068-28080 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T66 29845-29861 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T67 31139-31151 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T68 33350-33356 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T69 33728-33734 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T70 34082-34088 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T71 34278-34284 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T72 34443-34462 http://purl.obolibrary.org/obo/GO_0051607 denotes antiviral responses
T73 34834-34850 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T74 34950-34972 http://purl.obolibrary.org/obo/GO_0030183 denotes B cell differentiation
T75 34952-34972 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T76 35544-35561 http://purl.obolibrary.org/obo/GO_0042113 denotes B cell activation
T77 35546-35561 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T78 35630-35646 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T79 38428-38443 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T80 38519-38535 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T81 38893-38910 http://purl.obolibrary.org/obo/GO_0042113 denotes B cell activation
T82 38895-38910 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T83 39132-39149 http://purl.obolibrary.org/obo/GO_0042113 denotes B cell activation
T84 39134-39149 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T85 39636-39653 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T86 39638-39653 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T87 39841-39852 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T88 40251-40266 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T89 41449-41465 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T90 47014-47020 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T91 49387-49399 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T92 49657-49668 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T93 51035-51052 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T94 51037-51052 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T95 51765-51780 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T96 52129-52144 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T97 52645-52660 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T98 52867-52883 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T99 52991-52997 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T100 53739-53754 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T101 53796-53811 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T102 54172-54188 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T103 54371-54386 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T104 54450-54467 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T105 54452-54467 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T106 55210-55216 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T107 55388-55405 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T108 55390-55405 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T109 55448-55465 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T110 55450-55465 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T111 57033-57045 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T112 57131-57148 http://purl.obolibrary.org/obo/GO_0042113 denotes B cell activation
T113 57133-57148 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T114 57784-57800 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T115 57875-57891 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T116 58042-58059 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T117 58044-58059 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T118 58137-58153 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T119 58310-58325 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T120 59274-59289 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T121 59684-59701 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T122 59686-59701 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T123 59928-59945 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T124 59930-59945 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T125 59971-59977 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T126 60059-60080 http://purl.obolibrary.org/obo/GO_0046649 denotes lymphocyte activation
T127 60680-60696 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T128 60735-60750 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T129 60814-60829 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T130 60910-60925 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T131 60993-61008 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T132 61138-61150 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T133 61188-61203 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T134 63949-63954 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T135 66841-66847 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1Ra
T136 75262-75278 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T137 79037-79049 http://purl.obolibrary.org/obo/GO_0000003 denotes reproduction

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 12997-13000 GlycoEpitope denotes EM1 http://www.glycoepitope.jp/epitopes/AN0701
T2 13022-13025 GlycoEpitope denotes EM2 http://www.glycoepitope.jp/epitopes/AN0703
T3 13169-13172 GlycoEpitope denotes EM2 http://www.glycoepitope.jp/epitopes/AN0703
T4 13212-13215 GlycoEpitope denotes EM1 http://www.glycoepitope.jp/epitopes/AN0701
T5 13458-13461 GlycoEpitope denotes EM1 http://www.glycoepitope.jp/epitopes/AN0701
T6 15328-15331 GlycoEpitope denotes EM1 http://www.glycoepitope.jp/epitopes/AN0701
T7 18188-18191 GlycoEpitope denotes EM1 http://www.glycoepitope.jp/epitopes/AN0701
T8 19161-19164 GlycoEpitope denotes EM2 http://www.glycoepitope.jp/epitopes/AN0703
T9 19840-19843 GlycoEpitope denotes EM2 http://www.glycoepitope.jp/epitopes/AN0703

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1428-1448 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T2 3108-3119 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T3 6603-6614 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T4 7375-7397 Phenotype denotes chronic kidney disease http://purl.obolibrary.org/obo/HP_0012622
T5 7421-7441 Phenotype denotes thromboembolic event http://purl.obolibrary.org/obo/HP_0001907
T6 7553-7559 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T7 10420-10431 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T8 11311-11322 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T9 27388-27399 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T10 38622-38627 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T11 39658-39669 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T12 40491-40505 Phenotype denotes hyperlipidemia http://purl.obolibrary.org/obo/HP_0003077
T13 49483-49497 Phenotype denotes kidney disease http://purl.obolibrary.org/obo/HP_0000112
T14 49502-49521 Phenotype denotes renal insufficiency http://purl.obolibrary.org/obo/HP_0000083
T15 57265-57276 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T16 57300-57311 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T17 57390-57401 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T18 58334-58348 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T19 76518-76524 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T20 76636-76642 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T21 76676-76682 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T22 78121-78129 Phenotype denotes Oncology http://purl.obolibrary.org/obo/HP_0002664
T23 78162-78170 Phenotype denotes Oncology http://purl.obolibrary.org/obo/HP_0002664
T24 78433-78439 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-101 Sentence denotes Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
T2 103-111 Sentence denotes Abstract
T3 112-218 Sentence denotes COVID-19 is currently a global pandemic, but human immune responses to the virus remain poorly understood.
T4 219-333 Sentence denotes We analyzed 125 COVID-19 patients, and compared recovered to healthy individuals using high dimensional cytometry.
T5 334-472 Sentence denotes Integrated analysis of ~200 immune and ~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients.
T6 473-621 Sentence denotes A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching >30% of circulating B cells.
T7 622-708 Sentence denotes However, another subgroup had lymphocyte activation comparable to uninfected subjects.
T8 709-826 Sentence denotes Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change.
T9 827-940 Sentence denotes These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health.
T10 941-1038 Sentence denotes These immunotypes may have implications for the design of therapeutics and vaccines for COVID-19.
T11 1040-1136 Sentence denotes The COVID-19 pandemic has to date caused >7 million infections resulting in over 400,000 deaths.
T12 1137-1329 Sentence denotes Following infection with SARS-CoV2, COVID-19 patients can experience mild or even asymptomatic disease, or can present with severe disease requiring hospitalization and mechanical ventilation.
T13 1330-1380 Sentence denotes The case fatality rate can be as high as ~10% (1).
T14 1381-1503 Sentence denotes Some severe COVID-19 patients display an acute respiratory distress syndrome (ARDS), reflecting severe respiratory damage.
T15 1504-1644 Sentence denotes In acute respiratory viral infections, pathology can be mediated by the virus directly, by an overaggressive immune response, or both (2–4).
T16 1645-1833 Sentence denotes However, in severe COVID-19 disease, the characteristics of, and role for the immune response, as well as how these responses relate to clinical disease features, remain poorly understood.
T17 1834-2090 Sentence denotes SARS-CoV2 antigen-specific T cells have been identified in the central memory (CM), effector memory (EM), and CD45RA+ effector memory (EMRA) compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear.
T18 2091-2360 Sentence denotes Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6).
T19 2361-2578 Sentence denotes Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11).
T20 2579-2790 Sentence denotes T cell exhaustion (12, 13) or increased inhibitory receptor expression on peripheral T cells has also been reported (7, 14), though these inhibitory receptors are also increased following T cell activation (15).
T21 2791-3030 Sentence denotes Moreover, although there is evidence of T cell activation in COVID-19 patients (16), some studies have found decreases in polyfunctionality (12, 17) or cytotoxicity (12); however, these changes have not been observed in other studies (13).
T22 3031-3144 Sentence denotes Furthermore, how this activation should be viewed in the context of COVID-19 lymphopenia (18–20) remains unclear.
T23 3145-3264 Sentence denotes Most patients seroconvert within 7-14 days of infection and increased plasmablasts (PB) have been reported (16, 21–23).
T24 3265-3352 Sentence denotes However, the role of humoral responses in the pathogenesis of COVID-19 remains unclear.
T25 3353-3503 Sentence denotes Whereas IgG levels reportedly drop slightly ~8 weeks after symptom onset (24, 25), recovered patients maintain high Spike-specific IgG titers (6, 26).
T26 3504-3585 Sentence denotes IgA levels also can remain high and may correlate with disease severity (25, 27).
T27 3586-3688 Sentence denotes Furthermore, neutralizing antibodies can control SARS-CoV2 infection in vitro and in vivo (4, 28, 29).
T28 3689-3787 Sentence denotes Indeed, convalescent plasma containing neutralizing antibodies can improve clinical symptoms (30).
T29 3788-3987 Sentence denotes However, not all patients that recover from COVID-19 have detectable neutralizing antibodies (6, 26), suggesting a complex relationship between humoral and cellular response in COVID-19 pathogenesis.
T30 3988-4180 Sentence denotes Taken together, this previous work provokes questions about the potential diversity of immune responses to SARS-CoV2 and the relationship of this immune response diversity to clinical disease.
T31 4181-4308 Sentence denotes However, many studies describe small cohorts or even single patients, limiting a comprehensive interrogation of this diversity.
T32 4309-4488 Sentence denotes The relationship of different immune response features to clinical parameters, as well as the changes in immune responses and clinical disease over time, remain poorly understood.
T33 4489-4744 Sentence denotes Because potential therapeutics for COVID-19 patients include approaches to inhibit, activate, or otherwise modulate immune function, it is essential to define the immune response characteristics related to disease features in well-defined patient cohorts.
T34 4746-4845 Sentence denotes Acute SARS-CoV2 infection in humans results in broad changes in circulating immune cell populations
T35 4846-5067 Sentence denotes We conducted an observational study of hospitalized patients with COVID-19 at the University of Pennsylvania (UPenn IRB 808542) that included 149 hospitalized adults with confirmed SARS-CoV2 infection (COVID-19 patients).
T36 5068-5152 Sentence denotes Blood was collected at enrollment (typically ~24-72 hours after admission; Fig. 1A).
T37 5153-5235 Sentence denotes Additional samples were obtained from patients who remained hospitalized on day 7.
T38 5236-5452 Sentence denotes Blood was also collected from non-hospitalized patients who had recovered from documented SARS-CoV2 infection (Recovered Donors (RD); n = 46), as well as from healthy donors (HD; n = 70) (UPenn IRB 834263) (Fig. 1A).
T39 5453-5550 Sentence denotes Clinical metadata are available from the COVID-19 patients over the course of disease (table S1).
T40 5551-5754 Sentence denotes Of the total patients and donors, flow cytometry data from PBMCs was collected from COVID-19 patients (n = 125), RDs (n = 36), and HDs (n = 60) along with clinical metadata (Fig. 1A and tables S2 to S4).
T41 5755-5874 Sentence denotes Fig. 1 Clinical characterization of patient cohorts, inflammatory markers, and quantification of major immune subsets.
T42 5875-6061 Sentence denotes (A) Overview of patient cohorts in study, including healthy donors (HD), recovered donors (RD), and COVID-19 patients. (B) Quantification of key clinical parameters in COVID-19 patients.
T43 6062-6431 Sentence denotes Each dot is a COVID-19 patient; Healthy donor range indicated in green. (C) Spearman correlation and hierarchical clustering of indicated features for COVID-19 patients. (D) Representative flow cytometry plots and (E) frequencies of major immune subsets. (F) Ratio of CD4:CD8 T cells. (G) Spearman correlation of CD4:CD8 ratio and clinical lymphocyte count per patient.
T44 6432-6548 Sentence denotes Dark and light gray shaded regions represent clinical normal range and normal range based on study HD, respectively.
T45 6549-6799 Sentence denotes Vertical dashed line indicates clinical threshold for lymphopenia. (H) Spearman correlations of indicated subsets with various clinical features. (E and F) Each dot represents an individual healthy donor (green), RD (blue), or COVID-19 patient (red).
T46 6800-6926 Sentence denotes Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.
T47 6927-7137 Sentence denotes COVID-19 patients had a median age of 60 and were significantly older than HD and RD (median age of 41 and 29 respectively), though the age distributions for all three cohorts overlapped (Fig. 1A and fig. S1A).
T48 7138-7235 Sentence denotes For COVID-19 patients, median BMI was 29 (range 16-78), and 68% were African American (table S2).
T49 7236-7337 Sentence denotes Comorbidities in COVID-19 patients were dominated by cardiovascular risk factors (83% of the cohort).
T50 7338-7442 Sentence denotes Nearly 20% of subjects suffered from chronic kidney disease and 18% had a previous thromboembolic event.
T51 7443-7612 Sentence denotes A subset of patients (18%) were immunosuppressed, and 7% and 6% of patients were known to have a diagnosis of cancer or a pre-existing pulmonary condition, respectively.
T52 7613-7720 Sentence denotes 45% of the patients were treated with hydroxychloroquine (HCQ), 31% with steroids, and 29% with remdesivir.
T53 7721-7792 Sentence denotes Eighteen individuals died in the hospital or within a 30 day follow-up.
T54 7793-7907 Sentence denotes The majority of the patients were symptomatic at diagnosis and were enrolled ~9 days after initiation of symptoms.
T55 7908-8060 Sentence denotes Approximately 30% of patients required mechanical ventilation at presentation, with additional extracorporeal membrane oxygenation (ECMO) in four cases.
T56 8061-8185 Sentence denotes As has been reported for other COVID-19 patients (31), this COVID-19 cohort presented with a clinical inflammatory syndrome.
T57 8186-8391 Sentence denotes C reactive protein (CRP) was elevated in over 90% of subjects and LDH and D-dimer were increased in the vast majority, whereas ferritin was above normal in ~75% of COVID-19 patients (Fig. 1B and fig. S1B).
T58 8392-8469 Sentence denotes Similarly, troponin and NT-proBNP were increased in some patients (fig. S1B).
T59 8470-8654 Sentence denotes In a subset of patients where it was measured, IL-6 levels were normal in 5 patients, moderately elevated in 5 patients (6-20 pg/ml), and high in 31 patients (21-738 pg/ml) (fig. S1B).
T60 8655-8791 Sentence denotes Although white blood cell counts (WBC) were mostly normal, individual leukocyte populations were altered in COVID-19 patients (Fig. 1B).
T61 8792-8906 Sentence denotes A subset of patients had high PMN counts (fig. S1B) as described previously (8, 32) and in a companion study (33).
T62 8907-9017 Sentence denotes Furthermore, approximately half of the COVID-19 patients were clinically lymphopenic (ALC <1 THO/ul, Fig. 1B).
T63 9018-9115 Sentence denotes In contrast, monocyte, eosinophil, and basophil counts were mostly normal (Fig. 1B and fig. S1B).
T64 9116-9240 Sentence denotes To examine potential associations between these clinical features, we performed correlation analysis (Fig. 1C and fig. S1C).
T65 9241-9474 Sentence denotes This analysis revealed correlations between different COVID-19 disease severity metrics, as well as clinical features or interventions associated with more severe disease (e.g., D-dimer, vasoactive medication) (Fig. 1C and fig. S1C).
T66 9475-9607 Sentence denotes WBC and PMN also correlated with metrics of disease severity (e.g., APACHE III), as well as with IL-6 levels (Fig. 1C and fig. S1C).
T67 9608-9850 Sentence denotes Other relationships were also apparent, including correlations between age or mortality and metrics of disease severity and many other correlations between clinical measures of disease, inflammation, and co-morbidities (Fig. 1C and fig. S1C).
T68 9851-10037 Sentence denotes Thus, COVID-19 patients presented with varied pre-existing comorbidities, complex clinical phenotypes, evidence of inflammation in many patients, and clinically altered leukocyte counts.
T69 10038-10243 Sentence denotes To begin to interrogate immune responses to acute SARS-CoV2 infection, we compared peripheral blood mononuclear cells (PBMC) of COVID-19 patients, RD, and HD subjects using high dimensional flow cytometry.
T70 10244-10297 Sentence denotes We first focused on the major lymphocyte populations.
T71 10298-10536 Sentence denotes B cell and CD3+ T cell frequencies were decreased in COVID-19 patients compared to HD or RD subjects, reflecting clinical lymphopenia, whereas the relative frequency of non-B and non-T cells was correspondingly elevated (Fig. 1, D and E).
T72 10537-10704 Sentence denotes Although a numerical expansion of a non-B, non-T cell type is possible, loss of lymphocytes likely results in an increase in the relative frequency of this population.
T73 10705-10798 Sentence denotes This non-B, non-T cell population is also interrogated in more detail in the companion study.
T74 10799-11255 Sentence denotes Examining only CD3 T cells revealed preferential loss of CD8 T cells compared to CD4 T cells (Fig. 1, F and G, and fig. S1D); this pattern was reflected in absolute numbers estimated from the clinical data, where both CD4 and CD8 T cell counts in COVID-19 patients were lower than the clinical reference range, though the effect was more prominent for CD8 T cells (49/61 subjects below normal) than for CD4 T cells (38/61 subjects below normal) (fig. S1E).
T75 11256-11406 Sentence denotes These findings are consistent with previous reports of lymphopenia during COVID-19 disease (17–20) but highlight a preferential impact on CD8 T cells.
T76 11407-11511 Sentence denotes We next asked if the changes in these lymphocyte populations were related to clinical metrics (Fig. 1H).
T77 11512-11664 Sentence denotes Lower WBC counts were associated preferentially with lower frequencies of CD4 and CD8 T cells and increased non-T non-B, but not with B cells (Fig. 1H).
T78 11665-11839 Sentence denotes These lower T cell counts were associated with clinical markers of inflammation including ferritin, D-dimer, and hsCRP (Fig. 1H), whereas altered B cell frequencies were not.
T79 11840-11994 Sentence denotes Thus, hospitalized COVID-19 patients present with a complex constellation of clinical features that may be associated with altered lymphocyte populations.
T80 11996-12080 Sentence denotes SARS-CoV2 infection is associated with CD8 T cell activation in a subset of patients
T81 12081-12228 Sentence denotes We next applied high-dimensional flow cytometric analysis to further investigate lymphocyte activation and differentiation during COVID-19 disease.
T82 12229-12489 Sentence denotes We first used principal component analysis (PCA) to examine the general distribution of immune profiles from COVID-19 patients (n = 118), RD (n = 60), and HD (n = 36) using 193 immune parameters identified by high-dimensional flow cytometry (tables S5 and S6).
T83 12490-12603 Sentence denotes COVID-19 patients clearly segregated from RD and HD in PCA space, whereas RD and HD largely overlapped (Fig. 2A).
T84 12604-12679 Sentence denotes We investigated the immune features driving this COVID-19 immune signature.
T85 12680-12755 Sentence denotes Given their role in response to viral infection, we focused on CD8 T cells.
T86 12756-13105 Sentence denotes Six major CD8 T cell populations were examined using the combination of CD45RA, CD27, CCR7, and CD95 cell surface markers to define naïve (CD45RA+CD27+CCR7+CD95−), central memory (CD45RA−CD27+CCR7+ [CM]), effector memory (CD45RA−CD27+CCR7− [EM1], CD45RA−CD27−CCR7+ [EM2], CD45RA−CD27−CCR7− [EM3]), and EMRA (CD45RA+CD27−CCR7−) (Fig. 2B) CD8 T cells.
T87 13106-13226 Sentence denotes Among the CD8 T cell populations, there was an increase in the EM2 and EMRA populations and a decrease in EM1 (Fig. 2C).
T88 13227-13329 Sentence denotes Furthermore, the frequency of CD39+ cells was increased in COVID-19 patients compared to HD (Fig. 2D).
T89 13330-13473 Sentence denotes Although the frequency of PD-1+ cells was not different in the total CD8 population (Fig. 2D), it was increased for both CM and EM1 (fig. S2A).
T90 13474-13589 Sentence denotes Finally, all major CD8 T cell naive/memory populations in RD were comparable to HD (Fig. 2, C and D, and fig. S2A).
T91 13590-13716 Sentence denotes Fig. 2 CD8 T cell subset skewing and activation patterns in COVID-19 patients and potential links to T cell driven cytokines.
T92 13717-13970 Sentence denotes (A) Principle Component Analysis (PCA) of aggregated flow cytometry data. (B) Representative flow cytometry plots of the gating strategy for CD8 T cell subsets. (C) Frequencies of CD8 T cell subsets as indicated. (D) Frequencies of PD1+ and CD39+ cells.
T93 13971-14604 Sentence denotes Frequencies of (E) KI67+ and (F) HLA-DR+CD38+ cells and representative flow cytometry plots; green line at upper decile of HD. (G) (Top) Global viSNE projection of non-naïve CD8 T cells for all subjects pooled, non-naïve CD8 T cells from healthy donor (HD), recovered donor (RD), and COVID-19 patients concatenated and overlaid. (Bottom) viSNE projections of indicated protein expression. (H) viSNE projection of non-naïve CD8 T cell clusters identified by FlowSOM clustering. (I) Mean fluorescence intensity (MFI) as indicated, column-scaled z-score. (J) Percentage of non-naive CD8 T cells from each cohort in each FlowSOM cluster.
T94 14605-14757 Sentence denotes Boxes represent IQR. (C, D, E, F, J) Each dot represents an individual healthy donor (HD; green), recovered donor (RD; blue), or COVID-19 patient (red).
T95 14758-14884 Sentence denotes Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.
T96 14885-15041 Sentence denotes Most acute viral infections induce proliferation and activation of CD8 T cells detectable by increases in KI67 or co-expression of CD38 and HLA-DR (34, 35).
T97 15042-15188 Sentence denotes There was a significant increase in KI67+ and also HLA-DR+CD38+ non-naïve CD8 T cells in COVID-19 patients compared to HD or RD (Fig. 2, E and F).
T98 15189-15343 Sentence denotes In COVID-19 patients, KI67+ CD8 T cells were increased compared to HD and RD across all subsets of non-naïve CD8 T cells, including CM and EM1 (fig. S2B).
T99 15344-15536 Sentence denotes These data indicate broad T cell activation, potentially driven by bystander activation and/or homeostatic proliferation in addition to antigen-driven activation of virus-specific CD8 T cells.
T100 15537-15703 Sentence denotes This activation phenotype was confirmed by HLA-DR and CD38 co-expression that was significantly increased for all non-naïve CD8 T cell subsets (Fig. 2F and fig. S2C).
T101 15704-15797 Sentence denotes However, the magnitude of the KI67+ or CD38+HLA-DR+ CD8 T cells varied widely in this cohort.
T102 15798-15902 Sentence denotes The frequency of KI67+ CD8 T cells correlated with the frequency of CD38+HLA-DR+ CD8 T cells (fig. S2D).
T103 15903-16148 Sentence denotes However, the frequency of CD38+HLA-DR+, but not KI67+ CD8 T cells, was elevated in COVID-19 patients who had concomitant infection with another microbe but was not impacted by pre-existing immunosuppression or treatment with steroids (fig. S2E).
T104 16149-16414 Sentence denotes Moreover, these changes in CD8 T cell subsets in COVID-19 patients did not show clear correlations with individual metrics of clinical disease such as hsCRP or D-dimer (fig. S2E), although the frequency of KI67+ CD8 T cells associated with IL-6 and ferritin levels.
T105 16415-16574 Sentence denotes Although CD8 T cell activation was common, ~20% of patients had no increase in KI67+ or CD38+HLA-DR+ CD8 T cells above the level found in HD (Fig. 2, E and F).
T106 16575-16800 Sentence denotes Thus, although robust CD8 T cell activation was a clear characteristic of many hospitalized COVID-19 patients, a substantial fraction of patients had little evidence of CD8 T cell activation in the blood compared to controls.
T107 16801-16907 Sentence denotes To gain more insights, we applied global high-dimensional mapping of the 27-parameter flow cytometry data.
T108 16908-17043 Sentence denotes A tSNE representation of the data highlighted key regions of non-naïve CD8 T cells found preferentially in COVID-19 patients (Fig. 2G).
T109 17044-17324 Sentence denotes A major region of this tSNE map present in COVID-19 patients, but not HD or RD, were CD8 T cells that enriched for expression of CD38, HLA-DR, KI67, CD39, and PD1 (Fig. 2G), highlighting the co-expression of these activation markers with other features including CD95 (i.e., FAS).
T110 17325-17511 Sentence denotes Notably, although non-naïve CD8 T cells from RD were highly similar to those from HD, subtle differences existed, including in the lower region highlighted by T-bet and CX3CR1 (Fig. 2G).
T111 17512-17733 Sentence denotes To further define and quantify these differences between COVID-19 patients and controls, we performed FlowSOM clustering (Fig. 2H) and compared expression of fourteen CD8 T cell markers to identify each cluster (Fig. 2I).
T112 17734-17973 Sentence denotes This approach identified an increase in cells in several clusters including Clusters 1, 2, and 5 in COVID-19 patients, reflecting CD45RA+CD27−CCR7− TEMRA-like populations that expressed CX3CR1 and varying levels of T-bet (Fig. 2, I and J).
T113 17974-18138 Sentence denotes Clusters 12 and 14 contained CD27+HLA-DR+CD38+KI67+PD-1+ activated, proliferating cells and were more prevalent in COVID-19 disease (Fig. 2, I and J, and fig. S2F).
T114 18139-18299 Sentence denotes In contrast, the central Eomes+CD45RA−CD27+CCR7− EM1-like Cluster 6 and T-bethiCX3CR1+ Cluster 11 were decreased compared to HD (Fig. 2, I and J, and fig. S2F).
T115 18300-18448 Sentence denotes Thus, CD8 T cell responses in COVID-19 patients were characterized by populations of activated, proliferating CD8 T cells in a subgroup of patients.
T116 18450-18560 Sentence denotes SARS-CoV2 infection is associated with heterogeneous CD4 T cell responses and activation of CD4 T cell subsets
T117 18561-18728 Sentence denotes We next examined six well-defined CD4 T cell subsets as above for the CD8 T cells, including naïve, effector memory (EM1,2,3), central memory (CM), and EMRA (Fig. 3A).
T118 18729-19063 Sentence denotes Given the potential role of antibodies in the response to SARS-CoV2 (27, 29), we also analyzed circulating Tfh (CD45RA−PD1+CXCR5+ [cTfh] (36)) and activated circulating Tfh (CD38+ICOS+ [activated cTfh]), the latter of which may be more reflective of recent antigen encounter and emigration from the germinal center (37, 38) (Fig. 3A).
T119 19064-19184 Sentence denotes These analyses revealed a relative loss of naïve CD4 T cells compared to controls, but increased EM2 and EMRA (Fig. 3B).
T120 19185-19373 Sentence denotes The frequency of activated but not total cTfh was statistically increased in COVID-19 patients compared to HD, though this effect appeared to be driven by a subgroup of patients (Fig. 3B).
T121 19374-19535 Sentence denotes It is worth noting that activated cTfh frequencies were also higher in RD compared to HD (Fig. 3B), perhaps reflecting residual COVID-19 responses in that group.
T122 19536-19720 Sentence denotes Frequencies of KI67+ or CD38+HLA-DR+ non-naïve CD4 T cells were increased in COVID-19 patients (Fig. 3, C and E); however, this change was not equivalent across all CD4 T cell subsets.
T123 19721-19881 Sentence denotes The most substantial increases in both KI67+ and CD38+HLA-DR+ cells were found in the effector memory populations (EM, EM2, EM3) and in cTfh (fig. S3, A and B).
T124 19882-19964 Sentence denotes Although some subjects had increased activation of EMRA, this was less pronounced.
T125 19965-20074 Sentence denotes In contrast, PD1 expression was increased in all other non-naïve populations compared to HD or RD (fig. S3C).
T126 20075-20205 Sentence denotes Co-expression of CD38 and HLA-DR by non-naïve CD4 T cells correlated with the frequency of KI67+ non-naïve CD4 T cells (fig. S3D).
T127 20206-20343 Sentence denotes Moreover, the frequency of total non-naïve CD4 T cells that were CD38+HLA-DR+ correlated with the frequency of activated cTfh (fig. S3E).
T128 20344-20454 Sentence denotes In general, the activation of CD4 T cells was correlated with the activation of CD8 T cells (Fig. 3, D and F).
T129 20455-20686 Sentence denotes However, whereas ~2/3 of patients had KI67+ non-naïve CD4 or CD8 T cell frequencies above controls, ~1/3 of the COVID-19 patients had no increase in frequency of KI67+ CD4 or CD8 T cells above that observed in HD (Fig. 3, D and F).
T130 20687-20921 Sentence denotes Moreover, although most patients had similar proportions of activated CD4 T cells compared to CD8 T cells, there was a subgroup of patients that had disproportionate activation of CD4 T cells compared to CD8 T cells (Fig. 3, D and F).
T131 20922-21118 Sentence denotes KI67+ and CD38+HLA-DR+ non-naïve CD4 T cell frequencies correlated with ferritin and with APACHE III score (fig. S3F), suggesting a relationship between CD4 T cell activation and disease severity.
T132 21119-21267 Sentence denotes Immunosuppression did not impact CD4 T cell activation; however, early steroid administration was weakly associated with CD4 T cell KI67 (fig. S3F).
T133 21268-21565 Sentence denotes Together, these data highlight T cell activation in COVID-19 patients similar to what has been observed in other acute infections or vaccinations (37, 39, 40), but also identify patients with high, low, or essentially no T cell response based on KI67+ or CD38+HLA-DR+ compared to control subjects.
T134 21566-21673 Sentence denotes Fig. 3 CD4 T cell activation in a subset of COVID-19 patients associates with distinct CD4 T cell subsets.
T135 21674-21895 Sentence denotes (A) Representative flow cytometry plots of the gating strategy for CD4 T cell subsets. (B) Frequencies of CD4 T cell subsets as indicated. (C) Frequencies of KI67+ cells; green line at upper decile of healthy donors (HD).
T136 21896-22138 Sentence denotes Representative flow cytometry plots. (D) KI67+ cells from non-naïve CD4 T cells versus non-naïve CD8 T cells, Spearman correlation of COVID-19 patients. (E) Frequencies of HLA-DR+CD38+ cells; green line at upper decile of healthy donors (HD).
T137 22139-22763 Sentence denotes Representative flow cytometry plots. (F) HLA-DR+CD38+ cells from non-naïve CD4 versus non-naïve CD8 T cells, Spearman correlation of COVID-19 patients. (G) (Top) Global viSNE projection of non-naïve CD4 T cells for all subjects pooled, non-naïve CD4 T cells from HD, RD, and COVID-19 patients concatenated and overlaid. (Bottom) viSNE projections of indicated protein expression. (H) viSNE projection of non-naïve CD4 T cell clusters identified by FlowSOM clustering. (I) Mean fluorescence intensity (MFI) as indicated, column-scaled z-score. (J) Percentage of non-naïve CD4 T cells from each cohort in each FlowSOM cluster.
T138 22764-22913 Sentence denotes Boxes represent IQR. (B, C, E, J) Each dot represents an individual healthy donor (HD; green), recovered donor (RD; blue), or COVID-19 patient (red).
T139 22914-23040 Sentence denotes Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.
T140 23041-23258 Sentence denotes Projecting the global CD4 T cell differentiation patterns into the high-dimensional tSNE space again identified major alterations in the CD4 T cell response during COVID-19 infection compared to HDs and RDs (Fig. 3G).
T141 23259-23441 Sentence denotes In COVID-19 infection, there was a notable increase in density in tSNE regions that mapped to expression of CD38, HLA-DR, PD1, CD39, KI67, and CD95 (Fig. 3G), similar to CD8 T cells.
T142 23442-23556 Sentence denotes To gain more insight into these CD4 T cell changes, we again used a FlowSOM clustering approach (Fig. 3, H and I).
T143 23557-23841 Sentence denotes This analysis identified an increase in Clusters 13 and 14 in COVID-19 patients compared to HD and RD that represent populations expressing HLA-DR, CD38, PD1, KI67 and CD95, as well as Cluster 15 that contained Tbet+CX3CR1+ “effector-like” CD4 T cells (Fig. 3, I and J, and fig. S3G).
T144 23842-23997 Sentence denotes In contrast, this clustering approach identified reduction in CXCR5+ cTfh-like cells (Clusters 2, 3) in COVID-19 subjects compared to HD (Fig. 3, I and H).
T145 23998-24154 Sentence denotes Taken together, this multidimensional analysis revealed distinct populations of activated/proliferating CD4 T cells that were enriched in COVID-19 patients.
T146 24155-24413 Sentence denotes A key feature of COVID-19 disease is thought to be an inflammatory response that, at least in some patients, is linked to clinical disease manifestation (2, 4) and high levels of chemokines/cytokines, including IL-1RA, IL-6, IL-8, IL-10, and CXCL10 (11, 41).
T147 24414-24669 Sentence denotes To investigate the potential connection of inflammatory pathways to T cell responses, we performed 31-plex Luminex analysis on paired plasma and culture supernatants of anti-CD3/anti-CD28 stimulated PBMC from a subset of COVID-19 patients and HD controls.
T148 24670-24834 Sentence denotes Due to biosafety restrictions, only eight COVID-19 patient blood samples that were confirmed SARS-CoV2 RNA negative in the blood by PCR could be studied (fig. S4A).
T149 24835-25008 Sentence denotes Half of these COVID-19 patients had plasma CXCL10 concentrations that were ~15 fold higher than HD controls, whereas the remainder showed only a limited increase (fig. S4B).
T150 25009-25067 Sentence denotes CXCL9, CCL2, and IL-1RA were also significantly increased.
T151 25068-25188 Sentence denotes In contrast, chemokines involved in the recruitment of eosinophils (eotaxin) or activated T cells (CCL5) were decreased.
T152 25189-25418 Sentence denotes IL-6 was not elevated in this group of patients, in contrast to the subset of individuals tested clinically (fig. S1B), potentially because IL-6 was measured in the hospital setting often when systemic inflammation was suspected.
T153 25419-25686 Sentence denotes Following stimulation in vitro, PBMC from COVID-19 patients produced more CCL2, CXCL10, eotaxin, and IL-1RA than HD (fig. S4, C and D) and concentrations of CXCL10 and CCL2 correlated between the matched supernatant from stimulated PBMC and plasma samples (fig. S4E).
T154 25687-25819 Sentence denotes Finally, we investigated whether CD8 T cells from COVID-19 subjects were capable of producing IFNɣ following polyclonal stimulation.
T155 25820-26041 Sentence denotes Following ɑCD3+ɑCD28 stimulation, similar proportions of CD8 T cells from COVID-19 patients and HD controls produced IFNɣ, suggesting that PBMC from COVID-19 patients were responsive to TCR crosslinking (fig. S4, F to H).
T156 26042-26199 Sentence denotes The ability of T cells to produce IFNɣ following stimulation occurred in patients with increases in KI67 as well as patients with low KI67 (fig. S4, F to H).
T157 26200-26371 Sentence denotes Taken together, these data support the notion that a subgroup of COVID-19 patients has elevated systemic cytokines and chemokines, including myeloid recruiting chemokines.
T158 26373-26491 Sentence denotes COVID-19 infection is associated with increased frequencies of plasmablasts and proliferation of memory B cell subsets
T159 26492-26552 Sentence denotes B cell subpopulations were also altered in COVID-19 disease.
T160 26553-26767 Sentence denotes Whereas naïve B cell frequencies were similar in COVID-19 patients and RD or HD, the frequencies of class-switched (IgD−CD27+) and not-class-switched (IgD+CD27+) memory B cells were significantly reduced (Fig. 4A).
T161 26768-26879 Sentence denotes Conversely, frequencies of CD27−IgD− B cells and CD27+CD38+ PB were often robustly increased (Fig. 4, A and B).
T162 26880-27017 Sentence denotes In some cases, PB represented >30% of circulating B cells, similar to levels observed in acute Ebola or Dengue virus infections (42, 43).
T163 27018-27171 Sentence denotes However, these PB responses were only observed in ~2/3 of patients, with the remaining patients displaying PB frequencies similar to HD and RD (Fig. 4B).
T164 27172-27303 Sentence denotes KI67 expression was markedly elevated in all B cell subpopulations in COVID-19 patients compared to either control group (Fig. 4C).
T165 27304-27421 Sentence denotes This observation suggests a role for an antigen-driven response to infection and/or lymphopenia-driven proliferation.
T166 27422-27516 Sentence denotes Higher KI67 in PB may reflect recent generation in the COVID-19 patients compared to HD or RD.
T167 27517-27610 Sentence denotes CXCR5 expression was also reduced on all major B cell subsets in COVID-19 patients (Fig. 4D).
T168 27611-27731 Sentence denotes Loss of CXCR5 was not specific to B cells, however, as expression was also decreased on non-naïve CD4 T cells (Fig. 4E).
T169 27732-27954 Sentence denotes Changes in the B cell subsets were not associated with co-infection, immune suppression, or treatment with steroids or other clinical features, though a possible negative association of IL-6 and PB was revealed (fig. S5A).
T170 27955-28081 Sentence denotes These observations suggest that the B cell response phenotype of COVID-19 disease was not simply due to systemic inflammation.
T171 28082-28212 Sentence denotes Fig. 4 Deep profiling of COVID-19 patient B cell populations reveals robust plasmablast populations and other B cell alterations.
T172 28213-29490 Sentence denotes (A) Gating strategy and frequencies of non-PB B cell subsets. (B) Representative flow cytometry plots and frequencies of PB; green line at upper decile of HD. (C) Representative flow cytometry plots and frequencies of KI67+ B cells. (D) (Left) Representative histograms of CXCR5 expression and (right) CXCR5 GMFI of B cell subsets. (E) CXCR5 GMFI of non-naïve CD4 T cells and cTfh. (F) Spearman correlation between PB and activated cTfh. (G) Spearman correlation between PB and anti-SARS-CoV2 IgG. (H and I) Spearman correlation between activated cTfh and anti-SARS-CoV2 (H) IgM and (I) IgG. (J) (Top) Global viSNE projection of B cells for all subjects pooled, with B cell populations of each cohort concatenated and overlaid. (Bottom) viSNE projections of indicated protein expression. (K) Hierarchical clustering of Earth Mover’s Distance (EMD) using Pearson correlation, calculated pairwise for B cell populations for all subjects; row-scaled z-score. (L) Percentage of cohort in each EMD group. (M) Global viSNE projection of B cells for all subjects pooled, with EMD groups 1-3 concatenated and overlaid. (N) B cell clusters identified by FlowSOM clustering. (O) MFI as indicated; column-scaled z-score. (P) Percentage of B cells from each cohort in each FlowSOM cluster.
T173 29491-29831 Sentence denotes Boxes represent IQR. (A to F, P) Dots represent individual healthy donor (HD; green), recovered donor (RD; blue), or COVID-19 (red) subjects. (A to E, P) Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. (GtoI) Black horizontal line represents positive threshold.
T174 29832-29970 Sentence denotes During acute viral infections or vaccination, PB responses are transiently detectable in the blood and correlate with cTfh responses (40).
T175 29971-30144 Sentence denotes Comparing the frequency of PB to the frequency of total cTfh or activated cTfh, however, revealed a weak correlation only with activated cTfh (Fig. 4F and fig. S5, B and C).
T176 30145-30376 Sentence denotes Furthermore, some patients had robust activated cTfh responses but PB frequencies similar to controls, whereas other patients with robust PB responses had relatively low frequencies of activated cTfh (Fig. 4F and fig. S5, B and C).
T177 30377-30635 Sentence denotes However, there was also an association between PB frequency and CD38+HLA-DR+ or KI67+ CD4 T cells that might reflect a role for non-CXCR5+ CD4 T cell help (fig. S5D), but such a relationship did not exist for the equivalent CD8 T cell populations (fig. S5E).
T178 30636-30836 Sentence denotes Although ~70% of COVID-19 patients analyzed made antibodies against SARS-CoV2 spike protein (79/111 IgG; 77/115 IgM (44)), antibody levels did not correlate with PB frequencies (Fig. 4G and fig. S5F).
T179 30837-30960 Sentence denotes The occasional lack of antibody did not appear to be related to immunosuppression in a small number of patients (fig. S5G).
T180 30961-31200 Sentence denotes The lack of PB correlation with antibody suggests that a proportion of these large PB responses were: i) generated against SARS-CoV2 antigens other than the spike protein or ii) inflammation-driven and perhaps non-specific or low affinity.
T181 31201-31441 Sentence denotes Notably, anti-SARS-CoV2 IgG and IgM levels correlated with the activated, but not total, cTfh response, suggesting that at least a proportion of cTfh were providing SARS-CoV2-specific help to B cells (Fig. 4, H and I, and fig. S5, H and I).
T182 31442-31625 Sentence denotes Although defining the precise specificity of the robust PB populations will require future studies, these data suggest that at least some of the PB response is specific for SARS-CoV2.
T183 31626-31860 Sentence denotes Projecting the flow cytometry data for B cells from HD, RD, and COVID-19 patients in tSNE space revealed a distinct picture of B cell populations in COVID-19 compared to controls, whereas RD and HD were similar (Fig. 4J and fig. S5J).
T184 31861-31983 Sentence denotes The COVID-19 patient B cell phenotype was dominated by loss of CXCR5 and IgD compared to B cells from HD and RD (Fig. 4J).
T185 31984-32111 Sentence denotes Moreover, the robust PB response was apparent in the upper right section, highlighted by CD27, CD38, CD138, and KI67 (Fig. 4J).
T186 32112-32255 Sentence denotes The expression of KI67 and CD95 in these CD27+CD38+CD138+ PB (Fig. 4J) could suggest recent generation and/or emigration from germinal centers.
T187 32256-32389 Sentence denotes We next asked whether there were different groups of COVID-19 patients (or HD and RD) with global differences in the B cell response.
T188 32390-32622 Sentence denotes We used Earth Movers Distance (EMD) (45) to calculate similarities between the probability distributions within the tSNE map (Fig. 4J) and clustered so that individuals with the most similar distributions grouped together (Fig. 4K).
T189 32623-32776 Sentence denotes The majority of COVID-19 patients fell into two distinct groups (EMD Groups 1 and 3, Fig. 4L), suggesting two major “immunotypes” of the B cell response.
T190 32777-33012 Sentence denotes The remainder of the COVID-19 patients (~25%) clustered with the majority of the HD and all of the RD controls, supporting the observation that some individuals had limited evidence of response to infection in their B cell compartment.
T191 33013-33225 Sentence denotes To identify the population differences between HD, RD and COVID-19 patients, we performed FlowSOM clustering on the tSNE map, and also overlaid each individual EMD group onto this same tSNE map (Fig. 4, M and N).
T192 33226-33458 Sentence denotes EMD Group 2 containing mostly HD and RD was enriched for naive B cells (IgD+CD27−, Cluster 10) and CXCR5+IgD−CD27+ switched memory (Cluster 2) and, indeed, Clusters 2 and 10 were statistically reduced in COVID-19 patients (Fig. 4P).
T193 33459-33534 Sentence denotes EMD Groups 1 and 3 displayed distinct patterns across the FlowSOM clusters.
T194 33535-33686 Sentence denotes B cells from individuals in EMD Group 1 were enriched for the FlowSOM Clusters 1, 5, and 6, all of which were increased in COVID-19 patients (Fig. 4P).
T195 33687-33910 Sentence denotes FlowSOM Clusters 1 and 6 captured T-bet+ memory B cells whereas FlowSOM Cluster 5 contained the CD27+CD38+CD138+KI67+ PB, all of which were enriched in COVID-19 patients compared to controls (Fig. 4, O and P, and fig. S5K).
T196 33911-34147 Sentence denotes In contrast, B cells from COVID-19 patients in EMD Group 3 also showed enrichment for the PB FlowSOM Cluster 5, though less prominent than for EMD Group 1, but the T-bet+ memory B cell Cluster 1 was substantially reduced in EMD Group 3.
T197 34148-34368 Sentence denotes Thus, B cell responses were evident in many hospitalized COVID-19 patients, most often characterized by elevated PB, decreases in memory B cell subsets, enrichment in a T-bet+ B cell subset, and loss of CXCR5 expression.
T198 34369-34474 Sentence denotes Whether all of these changes in the B cell compartment were due to direct antiviral responses is unclear.
T199 34475-34701 Sentence denotes Although there was heterogeneity in the B cell responses, COVID-19 patients fell into two distinct patterns containing activated B cell responses and a third group of patients with little evidence of an active B cell response.
T200 34703-34776 Sentence denotes Temporal changes in immune cell populations occur during COVID-19 disease
T201 34777-34868 Sentence denotes A key question for hospitalized COVID-19 patients is how immune responses change over time.
T202 34869-35080 Sentence denotes Thus, we used the global tSNE projections of overall CD8 T cell, CD4 T cell, and B cell differentiation states to interrogate temporal changes in these populations between D0 and D7 of hospitalization (Fig. 5A).
T203 35081-35297 Sentence denotes Combining data for all patients revealed considerable stability of the tSNE distributions between D0 and D7 in CD8 T cell, CD4 T cell, and B cell populations, particularly for key regions of interest discussed above.
T204 35298-35496 Sentence denotes For example, for CD8 T cells, the region of the tSNE map containing KI67+ and CD38+HLA-DR+ CD8 T cell populations that was enriched in COVID-19 patients at D0 (Fig. 2) was preserved at D7 (Fig. 5A).
T205 35497-35590 Sentence denotes A similar temporal stability of CD4 T cell and B cell activation was also observed (Fig. 5A).
T206 35591-35673 Sentence denotes Fig. 5 Temporal relationships between immune responses and disease manifestation.
T207 35674-35861 Sentence denotes (A) Global viSNE projection of non-naïve CD8 T cells, non-naïve CD4 T cells, and B cells for all subjects pooled, with cells from COVID-19 patients at D0 and D7 concatenated and overlaid.
T208 35862-36133 Sentence denotes Frequencies of (B) KI67+ and HLA-DR+CD38+ CD4 T cells, (C) KI67+ and HLA-DR+CD38+ CD8 T cells, or (D) PBs as indicated for healthy donor (HD; green), recovered donor (RD; blue), or COVID-19 patients (red) with paired samples at D0 and D7 indicated by the connecting line.
T209 36134-36239 Sentence denotes Significance determined by paired Wilcoxon test: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.
T210 36240-36502 Sentence denotes Longitudinal patterns (see Methods) of (E) HLA-DR+CD38+ CD4 T cells or (F) PBs in COVID-19 patients shown as frequency and representative flow cytometry plots. (G) Spearman correlations of clinical parameters with longitudinal fold changes in immune populations.
T211 36503-36631 Sentence denotes Given this apparent stability between D0 and D7, we next investigated temporal changes in lymphocyte subpopulations of interest.
T212 36632-36942 Sentence denotes Although there were no obvious temporal changes in major phenotypically defined CD4 and CD8 T cell or B cell subsets, including plasmablasts (Fig. 5D), the frequencies of HLA-DR+CD38+ and KI67+ non-naïve CD4 (Fig. 5B) and KI67+ non-naïve CD8 T cells were statistically increased at D7 compared to D0 (Fig. 5C).
T213 36943-37122 Sentence denotes However, in all cases, these temporal patterns were complex, with frequencies of subpopulations in individual patients appearing to increase, decrease, or stay the same over time.
T214 37123-37293 Sentence denotes To quantify these inter-patient changes, we used a previously described data set (46) to define the stability of populations of interest in healthy individuals over time.
T215 37294-37473 Sentence denotes We then used the range of this variation over time to identify COVID-19 patients with changes in immune cell subpopulations beyond that expected in healthy subjects (see methods).
T216 37474-37669 Sentence denotes Using this approach, ~50% of patients had an increase in HLA-DR+CD38+ non-naïve CD4 T cells over time, whereas in ~30% of patients, these cells were stable and, in ~20%, they decreased (Fig. 5E).
T217 37670-37760 Sentence denotes For KI67+ non-naïve CD8 T cells, there were no individuals in whom the response decreased.
T218 37761-37860 Sentence denotes Instead, this proliferative CD8 T cell response stayed stable (~70%) or increased (~30%; fig. S6A).
T219 37861-38041 Sentence denotes Notably, for patients in the stable category, the median frequency of KI67+ non-naïve CD8 T cells was ~10%, almost 5-fold higher than the ~1% detected for HD and RD subjects (Figs.
T220 38042-38124 Sentence denotes 5C and 2E), suggesting a sustained CD8 T cell proliferative response to infection.
T221 38125-38316 Sentence denotes A similar pattern was observed for HLA-DR+CD38+ non-naïve CD8 (fig. S6B), where only ~10% of patients had a decrease in this population, whereas ~65% were stable and ~25% increased over time.
T222 38317-38717 Sentence denotes The high and even increasing activated or proliferating CD8 and CD4 T cell responses over ~1 week during acute viral infection contrasted with the sharp peak of KI67 in CD8 and CD4 T cells during acute viral infections, including smallpox vaccination with live vaccinia virus (47), live attenuated yellow fever vaccine YFV-17D (48), acute influenza virus infection (49), and acute HIV infection (35).
T223 38718-38833 Sentence denotes Approximately 42% of patients had sustained PB responses, at high levels (>10% of B cells) in many cases (Fig. 5F).
T224 38834-38995 Sentence denotes Thus, some patients displayed dynamic changes in T cell or B cell activation over 1 week in the hospital, but there were also other patients who remained stable.
T225 38996-39187 Sentence denotes In the latter case, some patients remained stable without clear activation of key immune populations whereas others had stable T and or B cell activation or numerical perturbation (fig. S6C).
T226 39188-39380 Sentence denotes We next asked whether these T and B cell dynamics related to clinical measures of COVID-19 disease, by correlating changes in immune features from D0 to D7 with clinical information (Fig. 5G).
T227 39381-39427 Sentence denotes These analyses revealed distinct correlations.
T228 39428-39670 Sentence denotes Decreases in all populations of responding CD4 and CD8 T cells (HLA-DR+CD38+, KI67+, or activated cTfh) between D0 and D7 were positively correlated with PMN and WBC counts, suggesting a relationship between T cell activation and lymphopenia.
T229 39671-39774 Sentence denotes Furthermore, decreases in CD4 and CD8 HLA-DR+CD38+ T cells positively correlated with APACHE III score.
T230 39775-39880 Sentence denotes However, stable HLA-DR+CD38+ CD4 T cell responses correlated with coagulation complications and ferritin.
T231 39881-39995 Sentence denotes Whereas decreasing activated cTfh over time was related to co-infection, the opposite pattern was observed for PB.
T232 39996-40277 Sentence denotes Increases in proliferating KI67+ CD4 and CD8 T cells over time were positively correlated to increasing anti-SARS-CoV2 antibody from day 0 to day 7, suggesting that some individuals might have been hospitalized during the expansion phase of the antiviral immune response (Fig. 5G).
T233 40278-40381 Sentence denotes Finally, neither Remdesivir nor HCQ treatment correlated with any of these immune features in Fig. 5G).
T234 40382-40597 Sentence denotes Examining categorical rather than continuous clinical data, 80% of patients with decreasing PB over time had hyperlipidemia, whereas only 20% of patients with increasing PB over time had this comorbidity (fig. S6D).
T235 40598-40862 Sentence denotes All patients who had decreasing CD38+HLA-DR+ CD8 T cells from day 0 to day 7 were treated with early vasoactive medication or inhaled nitric oxide whereas these treatments were less common for patients with stable or increasing CD38+HLA-DR+ CD8 T cells (fig. S6E).
T236 40863-41025 Sentence denotes In contrast, vasoactive medication, inhaled nitric oxide, and early steroid treatment were equally common in patients with increasing or decreasing PB (fig. S6D).
T237 41026-41133 Sentence denotes Similar patterns were apparent for other T cell populations and these categorical clinical data (fig. S6F).
T238 41134-41269 Sentence denotes Thus, the trajectory of change in the T and B cell response in COVID-19 patients was strongly connected to clinical metrics of disease.
T239 41271-41400 Sentence denotes Identifying “immunotypes” and relationships between circulating B and T cell responses with disease severity in COVID-19 patients
T240 41401-41757 Sentence denotes To further investigate the relationship between immune responses and COVID-19 disease trajectory, we stratified the COVID-19 patients (n = 125) into eight different categories according to the NIH Ordinal Severity Scale ranging from COVID 1 (death) and COVID 2 (requiring maximal clinical intervention) to COVID 8 (at home with no required care) (Fig. 6A).
T241 41758-41865 Sentence denotes We then asked how changes in T and B cell populations defined above on D0 were related to disease severity.
T242 41866-42018 Sentence denotes More severe disease was associated with lower frequencies of CD8 and CD4 T cells, with a greater effect on CD8 T cells in less severe disease (Fig. 6B).
T243 42019-42214 Sentence denotes Taking all patients together, there were no statistically significant changes in the major T cell and B cell subsets related to disease severity though some trends were present (fig. S7, A to C).
T244 42215-42375 Sentence denotes In contrast, HLA-DR+CD38+ CD8 T cells as well as both KI67+ and HLA-DR+CD38+ CD4 T cells were increased in patients with more severe disease (fig. S7, D and E).
T245 42376-42496 Sentence denotes Fig. 6 High dimensional analysis of immune phenotypes with clinical data reveals distinct COVID-19 patient immunotypes.
T246 42497-42591 Sentence denotes (A) NIH ordinal scale for COVID-19 clinical severity. (B) Frequencies of major immune subsets.
T247 42592-43085 Sentence denotes Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. (C) Heatmap of indicated immune parameters by row; donor type, disease severity, and mortality indicated across top. (D) UMAP projection of aggregated flow cytometry data. (E) Transformed UMAP projection; density contours drawn separately for healthy donor (HD), recovered donor (RD), and COVID-19 subjects (see Methods). (F) Bars represent mean of UMAP Component 1.
T248 43086-43284 Sentence denotes Dots represent individual subjects; bars shaded by subject group and/or severity score. (G) Density contour plots indicating variation of specified immune features across UMAP Component coordinates.
T249 43285-43406 Sentence denotes Relative expression (according to heat scale) shown for both individual patients (points) and overall density (contours).
T250 43407-44084 Sentence denotes Spearman’s Rank Correlation coefficient (ρ) and p-value for each feature vs. Component 1 (C1) and Component 2 (C2) shown. (H) (Left) Spearman correlation between UMAP Components 1 and 2 and FlowSOM clusters. (Right) Select FlowSOM clusters and their protein expression. (I) Spearman correlation between UMAP Components 1 and 2 and clinical metadata. (J) Heatmap of immune parameters used to define Immunotype 3 indicated by row; disease severity and mortality indicated across top. (K) (Left) Transformed UMAP projection; patient status for Immunotype 3 indicated by color. (Right) Spearman correlation between Immunotype 3 and disease severity, mortality, and UMAP Components.
T251 44085-44151 Sentence denotes There were two challenges with extracting meaning from these data.
T252 44152-44278 Sentence denotes First, there was considerable inter-patient heterogeneity for each of these immune features related to disease severity score.
T253 44279-44436 Sentence denotes Second, these binary comparisons (e.g., one immune subset versus one clinical feature) vastly underutilized the high dimensional information in this dataset.
T254 44437-44559 Sentence denotes Thus, we next visualized major T and B cell subpopulation data as it related to clinical disease severity score (Fig. 6C).
T255 44560-44682 Sentence denotes Data were clustered based on immune features and then overlaid with the disease severity score over time for each patient.
T256 44683-44804 Sentence denotes This analysis revealed groups of patients with similar composite immune signatures of T and B cell populations (Fig. 6C).
T257 44805-44952 Sentence denotes When individual CD8 T cell, CD4 T cell, or B cell populations were examined, a similar concept of patient subgroups emerged (fig. S7, F, G, and H).
T258 44953-45165 Sentence denotes These data suggested the idea of “immunotypes” of COVID-19 patients based on integrated responses of T and B cells, though some individual cell types and/or phenotypes separated patients more clearly than others.
T259 45166-45378 Sentence denotes These approaches provided insight into potential immune phenotypes associated with patients with severe disease, but suffered from the use of a small number of manually selected T or B cell subsets or phenotypes.
T260 45379-45706 Sentence denotes We therefore next employed Uniform Manifold Approximation and Projection (UMAP) to distill the ~200 flow cytometry features (see tables S5 and S6) representing the immune landscape of COVID-19 disease in two dimensional space, creating compact meta features (or Components) that could then be correlated with clinical outcomes.
T261 45707-45904 Sentence denotes This analysis revealed a clear trajectory from HD to COVID-19 patients (Fig. 6D), which we centered and aligned with the horizontal axis (“Component 1”) to facilitate downstream analysis (Fig. 6E).
T262 45905-46035 Sentence denotes An orthogonal vertical axis coordinate (“Component 2”) also existed that captured non-overlapping aspects of the immune landscape.
T263 46036-46158 Sentence denotes We next calculated the mean of Component 1 for each patient group, with COVID-19 patients separated by severity (Fig. 6E).
T264 46159-46273 Sentence denotes The contribution of Component 1 clearly increased in a stepwise manner with increasing disease severity (Fig. 6F).
T265 46274-46348 Sentence denotes Interestingly, RD were subtly positioned between HD and COVID-19 patients.
T266 46349-46515 Sentence denotes Component 1 remained an independent predictor of disease severity (P = 5.5 × 10−5) even after adjusting for the confounding demographic factors of age, sex, and race.
T267 46516-46628 Sentence denotes We next investigated how the UMAP Components were associated with individual immune features (tables S5 and S6).
T268 46629-46765 Sentence denotes UMAP Component 1 captured immune features, including the relative loss of CD4 and CD8 T cells and increase in nonB:nonT cells (Fig. 6G).
T269 46766-46812 Sentence denotes PB also associated with Component 1 (Fig. 6G).
T270 46813-46901 Sentence denotes Other individual B cell features were differentially captured by UMAP Component 1 and 2.
T271 46902-47066 Sentence denotes Component 1 contained a signal for T-bet+ PB populations (table S5) whereas Component 2 was enriched for T-bet+ memory B cells and CD138+ PB populations (table S6).
T272 47067-47286 Sentence denotes Activated HLA-DR+CD38+ and KI67+ CD4 and CD8 T cells had contributions to both Component 1 and Component 2, with these features residing in the upper right corner of the UMAP plot (Fig. 6, G and H, and fig. S8, A to D).
T273 47287-47471 Sentence denotes In contrast, T-bet+ non-naïve CD8 T cells were strongly associated with Component 2 whereas T-bet+ non-naïve CD4 T cells were also linked to Component 1 (Fig. 6G and tables S5 and S6).
T274 47472-47610 Sentence denotes Eomes+ CD8 or CD4 T cells were both associated with Component 2 and negatively associated with Component 1 (Fig. 6G and tables S5 and S6).
T275 47611-47668 Sentence denotes We next took advantage of the FlowSOM clustering in Figs.
T276 47669-47820 Sentence denotes 2 to 4 that identified individual immune cell types most perturbed in COVID-19 patients and linked these FlowSOM clusters to UMAP Components (Fig. 6H).
T277 47821-48039 Sentence denotes For non-naïve CD8 T cells, FlowSOM Cluster 11 that contained T-bet+CX3CR1+ but non-proliferating effector-like cells was positively correlated with UMAP Component 2 and negatively correlated with Component 1 (Fig. 6H).
T278 48040-48277 Sentence denotes In contrast, FlowSOM Cluster 14 contained activated, proliferating PD-1+CD39+ cells that might reflect either recently generated effector or possibly exhausted CD8 T cells (50) and was strongly associated with UMAP Component 1 (Fig. 6H).
T279 48278-48545 Sentence denotes For CD4 T cells, FlowSOM Cluster 14, containing activated, proliferating CD4 T cells, was captured by both UMAP Components, whereas a second activated CD4 T cell population that also expressed CD95 (FlowSOM Cluster 13) was only captured by UMAP Component 1 (Fig. 6H).
T280 48546-48668 Sentence denotes In addition, Component 1 was negatively correlated with CD4 T cell FlowSOM Clusters 2 and 3 that contained cTfh (Fig. 6H).
T281 48669-48872 Sentence denotes Finally, for B cells, the FlowSOM Cluster of T-bet+CD138+ PB (Cluster 5) was positively correlated with Component 1 whereas the Tbet-CD138+ Cluster 3 was negatively correlated with Component 1 (Fig. 6H).
T282 48873-49041 Sentence denotes Locations in the UMAP immune landscape were dynamic, changing from D0 to D7 for both Component 1 and Component 2 consistent with the data in Fig. 5 and fig. S9, A to F.
T283 49042-49159 Sentence denotes The most dynamic changes in Component 1 were associated with the largest increases in IgM antibody levels (fig. S9G).
T284 49160-49320 Sentence denotes Given the association of the UMAP Component 1 with disease severity, we next examined the connections between UMAP Components with individual clinical features.
T285 49321-49532 Sentence denotes UMAP Component 1 correlated with several clinical measurements of inflammation (e.g., ferritin, hsCRP, IL-6), co-infection, organ failure (APACHE III), and acute kidney disease and renal insufficiency (Fig. 6I).
T286 49533-49696 Sentence denotes It was interesting, however, that, although D-dimer was elevated, this feature did not correlate with UMAP Component 1, but coagulation complication did (Fig. 6I).
T287 49697-49816 Sentence denotes Several antibody features also correlated with Component 1 consistent with some of the immune features discussed above.
T288 49817-50041 Sentence denotes In contrast, Component 2 lacked positive correlation to many of these clinical features of disease and rather was negatively correlated only to eosinophil count, NSAID use, and subsequent treatment with Remdesivir (Fig. 6I).
T289 50042-50237 Sentence denotes UMAP Component 1, but not Component 2, also correlated with mortality, although there were clearly patients with high Component 2, but low Component 1 who succumbed to COVID-19 disease (Fig. 6E).
T290 50238-50536 Sentence denotes These data indicate that the immune features captured by UMAP Component 1 have a strong relationship to many features of disease severity, whereas other features of immune dynamics during COVID-19 disease captured by UMAP Component 2 have a distinct relationship with clinical disease presentation.
T291 50537-50705 Sentence denotes More positive values in UMAP Components 1 or 2 captured mainly signals of change or differences in individual immune features in COVID-19 disease compared to HD and RD.
T292 50706-51122 Sentence denotes UMAP Component 1 captured an immunotype (Immunotype 1) that was characterized by effector or highly activated CD4 T cells, low cTfh, some CD8 TEMRA-like activation, possibly hyperactivated CD8 T cells, and Tbet+ PB, whereas Component 2 or Immunotype 2 captured Tbetbright effector-like CD8 T cells, lacked some of the robust CD4 T cell activation but has some features of proliferating B cells (Fig. 6G and fig. S8).
T293 51123-51159 Sentence denotes However, the data presented in Figs.
T294 51160-51253 Sentence denotes 1 to 5 also suggested a subset of patients with minimal activation of T and B cell responses.
T295 51254-51449 Sentence denotes To investigate this immune signature, we identified 20 patients who had responses more similar to HD and RD for five activated/responding B and T cell populations (Fig. 6J, middle, and fig. S10).
T296 51450-51617 Sentence denotes If the UMAP Components 1 and 2 captured two distinct “immunotypes” of patient responses to SARS-CoV2 infection, this group of 20 patients represent a third immunotype.
T297 51618-51940 Sentence denotes Immunotype 3 was negatively associated with UMAP Components 1 and 2 and negatively associated with disease severity, suggesting that a less robust immune response during COVID-19 was associated with less severe pathology (Fig. 6K and fig. S10), despite the fact that these patients were hospitalized with COVID-19 disease.
T298 51941-52051 Sentence denotes These data further emphasize the different ways patients can present and possibly succumb to COVID-19 disease.
T299 52052-52161 Sentence denotes These patterns may be related to pre-existing conditions in combination with immune response characteristics.
T300 52162-52283 Sentence denotes It is likely that additional immune features, such as comprehensive serum cytokine measurements, will improve this model.
T301 52284-52517 Sentence denotes Nevertheless, the current computational approach integrating deep immune profiling with disease severity trajectory and other clinical information revealed distinct patient immunotypes linked to distinct clinical outcomes (fig. S11).
T302 52519-52529 Sentence denotes Discussion
T303 52530-52605 Sentence denotes The T and B cell response to SARS-CoV2 infection remains poorly understood.
T304 52606-52757 Sentence denotes Some studies suggest an overaggressive immune response leading to immunopathology (51) whereas others suggest T cell exhaustion or dysfunction (12–14).
T305 52758-52884 Sentence denotes Autopsies revealed high virus levels in the respiratory tract and other tissues (52), suggesting ineffective immune responses.
T306 52885-53003 Sentence denotes Nevertheless, non-hospitalized subjects who recovered from COVID-19 had evidence of virus-specific T cell memory (53).
T307 53004-53157 Sentence denotes SARS-CoV2-specific antibodies are also found in convalescent subjects and patients are currently being treated with convalescent plasma therapy (30, 54).
T308 53158-53325 Sentence denotes However, COVID-19 ICU patients have SARS-CoV2-specific antibodies (30), raising the question of why patients with these antibody responses are not controlling disease.
T309 53326-53499 Sentence denotes In general, these studies report on single patients or small cohorts and comprehensive deep immune profiling of a large number of COVID-19 hospitalized patients is limiting.
T310 53500-53637 Sentence denotes Such knowledge would address the critical question of whether there is a common profile of immune dysfunction in critically ill patients.
T311 53638-53776 Sentence denotes Such data would also help guide testing of therapeutics to enhance, inhibit, or otherwise tailor the immune response in COVID-19 patients.
T312 53777-53902 Sentence denotes To interrogate the immune response patterns of COVID-19 hospitalized patients, we studied a cohort of ~125 COVID-19 patients.
T313 53903-54223 Sentence denotes We used high dimensional flow cytometry to perform deep immune profiling of individual B and T cell populations, with temporal analysis of immune changes during infection, and combined this profiling with extensive clinical data to understand the relationships between immune responses to SARS-CoV2 and disease severity.
T314 54224-54274 Sentence denotes Using this approach, we made several key findings.
T315 54275-54387 Sentence denotes First, a defining feature of COVID-19 disease in hospitalized patients was heterogeneity of the immune response.
T316 54388-54607 Sentence denotes Many COVID-19 patients displayed robust CD8 T cell and/or CD4 T cell activation and proliferation and PB responses, though a considerable subgroup of patients (~20%) had minimal detectable response compared to controls.
T317 54608-54782 Sentence denotes Furthermore, even within those patients who mounted detectable B and T cell responses during COVID-19 disease, the immune characteristics of this response were heterogeneous.
T318 54783-55351 Sentence denotes By deep immune profiling, we identified three immunotypes in hospitalized COVID-19 patients including: (1) patients with robust activation and proliferation of CD4 T cells, relative lack of cTfh, together with modest activation of TEMRA-like as well as highly activated or exhausted CD8 T cells and a signature of T-bet+ PB; (2) Tbetbright effector-like CD8 T cell responses, less robust CD4 T cell responses, and Ki67+ PB and memory B cells; and (3) an immunotype largely lacking detectable lymphocyte response to infection, suggesting a failure of immune activation.
T319 55352-55510 Sentence denotes UMAP embedding further resolved the T cell activation immunotype, suggesting a link between CD4 T cell activation, Immunotype 1, and increased severity score.
T320 55511-55701 Sentence denotes Although differences in age and race existed between the cohorts and could impact some immune variables, the major UMAP relationships were preserved even when correcting for these variables.
T321 55702-55814 Sentence denotes Thus, these immunotypes may reflect fundamental differences in the ways patients respond to SARS-CoV2 infection.
T322 55815-55886 Sentence denotes A second key observation from these studies was the robust PB response.
T323 55887-55993 Sentence denotes Some patients had PB frequencies rivaling those found in acute Ebola or Dengue infection (34, 42, 43, 55).
T324 55994-56094 Sentence denotes Furthermore, blood PB frequencies are typically correlated with blood activated cTfh responses (40).
T325 56095-56183 Sentence denotes However, in COVID-19 patients, this relationship between PB and activated cTfh was weak.
T326 56184-56478 Sentence denotes The lack of relationship between these two cell types in this disease could be due to T cell-independent B cell responses, lack of activated cTfh in peripheral blood at this time point, or lower CXCR5 expression observed across lymphocyte populations, making it more difficult to identify cTfh.
T327 56479-56678 Sentence denotes Indeed, activated (CD38+HLA-DR+) CD4 T cells could play a role in providing B cell help, perhaps as part of an extrafollicular response, but such a connection was also not robust in the current data.
T328 56679-56803 Sentence denotes Most ICU patients made SARS-CoV2-specific antibodies, suggesting that at least part of the PB response was antigen-specific.
T329 56804-56944 Sentence denotes Indeed, the cTfh response did correlate with antibodies suggesting that at least some of the humoral response is targeted against the virus.
T330 56945-57076 Sentence denotes Future studies will be needed to address the antigen specificity, ontogeny, and role in pathogenesis for these robust PB responses.
T331 57077-57203 Sentence denotes A striking feature of some patients with strong T and B cell activation and proliferation was the durability of this response.
T332 57204-57294 Sentence denotes This T and B activation was interesting considering clinical lymphopenia in many patients.
T333 57295-57355 Sentence denotes This lymphopenia, however, was preferential for CD8 T cells.
T334 57356-57557 Sentence denotes It may be notable that such focal lymphopenia preferentially affecting CD8 T cells is also a feature of acute Ebola infection of macaques and is associated with CD95 expression and severe disease (55).
T335 57558-57636 Sentence denotes Indeed CD95 was associated with activated T cell clusters in COVID-19 disease.
T336 57637-57847 Sentence denotes Nevertheless, the frequency of the KI67+ or CD38+HLA-DR+ CD8 and CD4 T cell responses in COVID-19 patients was similar in magnitude to other acute viral infections or live attenuated vaccines in humans (47–49).
T337 57848-58012 Sentence denotes However, during many acute viral infections, peak CD8 or CD4 T cell responses and the window of detectable PB in peripheral blood are relatively short (43, 56, 57).
T338 58013-58264 Sentence denotes The stability of CD8 and CD4 T cell activation and PB responses during COVID-19 disease suggests a prolonged period of peak immune responses at the time of hospitalization or perhaps a failure to appropriately down-regulate responses in some patients.
T339 58265-58381 Sentence denotes These ideas would fit with an overaggressive immune response and/or “cytokine storm” (2) in this subset of patients.
T340 58382-58568 Sentence denotes Indeed, in some patients, we found elevated serum cytokines and that stimulation of T cells in vitro provoked cytokines and chemokines capable of activating and recruiting myeloid cells.
T341 58569-58738 Sentence denotes A key question will be how to identify these patients for selected immune regulatory treatment while avoiding treating patients with already weak T and B cell responses.
T342 58739-58927 Sentence denotes An additional major finding was the ability to connect immune features not only to disease severity at the time of sampling but also to the trajectory of disease severity change over time.
T343 58928-59094 Sentence denotes Using correlative analyses, we observed relationships between features of the different immunotypes, patient comorbidities, and clinical features of COVID-19 disease.
T344 59095-59320 Sentence denotes By integrating ~200 immune features with extensive clinical data, disease severity scores, and temporal changes, we built an integrated computational model that connected patient immune response phenotype to disease severity.
T345 59321-59476 Sentence denotes Moreover, this UMAP embedding approach allowed us to connect these integrated immune signatures back to specific clinically measurable features of disease.
T346 59477-59615 Sentence denotes The integrated immune signatures captured by Components 1 and 2 in this UMAP model provided support for the notion of Immunotypes 1 and 2.
T347 59616-60027 Sentence denotes These analyses suggested that Immunotype 1, comprised of robust CD4 T cell activation, paucity of cTfh with proliferating effector/exhausted CD8 T cells and T-bet+ PB involvement, was connected to more severe disease whereas Immunotype 2, characterized by more traditional effector CD8 T cells subsets, less CD4 T cell activation and proliferating PB and memory B cells, was better captured by UMAP Component 2.
T348 60028-60278 Sentence denotes Immunotype 3, in which minimal lymphocyte activation response was observed, may represent ~20% of COVID-19 patients and is a potentially important scenario to consider as patients who may have failed to mount a robust antiviral T and B cell response.
T349 60279-60480 Sentence denotes This UMAP integrated modeling approach could be improved in the future with additional data on other immune cell types and/or comprehensive data for circulating inflammatory mediators for all patients.
T350 60481-60667 Sentence denotes Nevertheless, these findings provoke the idea of the tailoring clinical treatments or future immune-based clinical trials to patients whose immunotype suggests greater potential benefit.
T351 60668-60883 Sentence denotes Respiratory viral infections can cause pathology as a result of an immune response that is too weak and results in virus-induced pathology, or an immune response that is too strong and leads to immunopathology (58).
T352 60884-61151 Sentence denotes Our data suggest that the immune response of hospitalized COVID-19 patients may fall across this spectrum of immune response patterns, presenting as distinct immunotypes linked to clinical features, disease severity, and temporal changes in response and pathogenesis.
T353 61152-61295 Sentence denotes This study provides a compendium of immune response data and also an integrated framework as a “map” for connecting immune features to disease.
T354 61296-61471 Sentence denotes By localizing patients on an immune topology map built on this dataset, we can begin to infer which types of therapeutic interventions may be most useful in specific patients.
T355 61473-61494 Sentence denotes Materials and methods
T356 61496-61544 Sentence denotes Patients, subjects, and clinical data collection
T357 61545-61731 Sentence denotes Patients admitted to the Hospital of the University of Pennsylvania with a positive SARS-CoV2 PCR test were screened and approached for informed consent within 3 days of hospitalization.
T358 61732-61835 Sentence denotes Healthy donors (HD) were adults with no prior diagnosis of or recent symptoms consistent with COVID-19.
T359 61836-61926 Sentence denotes Normal reference ranges for HDs were the UPenn clinical laboratory values shaded in green.
T360 61927-62097 Sentence denotes Recovered COVID-19 subjects (RD) were adults with a prior positive COVID-19 PCR test by self-report who met the definition of recovery by the Centers for Disease Control.
T361 62098-62262 Sentence denotes HD and RD were recruited initially by word of mouth and subsequently through a centralized University of Pennsylvania resource website for COVID-19-related studies.
T362 62263-62312 Sentence denotes Peripheral blood was collected from all subjects.
T363 62313-62430 Sentence denotes For inpatients, clinical data were abstracted from the electronic medical record into standardized case report forms.
T364 62431-62596 Sentence denotes ARDS was categorized in accordance with the Berlin definition reflecting each subject’s worst oxygenation level and with physician adjudication of chest radiographs.
T365 62597-62776 Sentence denotes APACHE III scoring was based on data collected in the first 24 hours of ICU admission or the first 24 hours of hospital admission for subjects admitted to general inpatient units.
T366 62777-62869 Sentence denotes Clinical laboratory data were abstracted from the date closest to research blood collection.
T367 62870-62914 Sentence denotes HD and RD completed a survey about symptoms.
T368 62915-63024 Sentence denotes After enrollment, the clinical team determined three patients to be COVID-negative and/or PCR false positive.
T369 63025-63079 Sentence denotes Two of these patients were classified as Immunotype 3.
T370 63080-63163 Sentence denotes In keeping with inclusion criteria, these subjects were maintained in the analysis.
T371 63164-63282 Sentence denotes The statistical significance reported in Fig. 6K did not change when analysis was repeated without the three patients.
T372 63283-63456 Sentence denotes All participants or their surrogates provided informed consent in accordance with protocols approved by the regional ethical research boards and the Declaration of Helsinki.
T373 63458-63475 Sentence denotes Sample processing
T374 63476-63550 Sentence denotes Peripheral blood was collected into sodium heparin tubes (BD, Cat#367874).
T375 63551-63618 Sentence denotes Tubes were spun (15 min, 3000 rpm, RT), plasma removed, and banked.
T376 63619-63809 Sentence denotes Remaining whole blood was diluted 1:1 with 1% RPMI (table S7) and layered into a SEPMATE tube (STEMCELL Technologies, Cat#85450) pre-loaded with lymphoprep (Alere Technologies, Cat#1114547).
T377 63810-63998 Sentence denotes SEPMATE tubes were spun (10 min, 1200xg, RT) and the PBMC layer collected, washed with 1% RPMI (10 min, 1600 rpm, RT) and treated with ACK lysis buffer (5 min, ThermoFisher, Cat#A1049201).
T378 63999-64078 Sentence denotes Samples were filtered with a 70 μm filter, counted, and aliquoted for staining.
T379 64080-64108 Sentence denotes Antibody panels and staining
T380 64109-64186 Sentence denotes Approximately 1-5×106 freshly isolated PBMCs were used per patient per stain.
T381 64187-64267 Sentence denotes See table S7 for buffer information and table S8 for antibody panel information.
T382 64268-64389 Sentence denotes PBMCs were stained with live/dead mix (100 μl, 10 min, RT), washed with FACS buffer, and spun down (1500 rpm, 5 min, RT).
T383 64390-64504 Sentence denotes PBMCs were incubated with 100 μl of Fc block (RT, 10 min) before a second wash (FACS buffer, 1500 rpm, 5 min, RT).
T384 64505-64606 Sentence denotes Pellet was resuspended in 25 μl of chemokine receptor staining mix, and incubated at 37°C for 20 min.
T385 64607-64743 Sentence denotes Following incubation, 25 μl of surface receptor staining mix was directly added and the PBMCs were incubated at RT for a further 45 min.
T386 64744-64917 Sentence denotes PBMCs were washed (FACS buffer, 1500 rpm, 5 min, RT) and stained with 50 μl of secondary antibody mix for 20 min at RT, then washed again (FACS buffer, 1500 rpm, 5 min, RT).
T387 64918-65059 Sentence denotes Samples were fixed and permeabilized by incubating in 100 μl of Fix/Perm buffer (RT, 30 min) and washed in Perm Buffer (1800 rpm, 5 min, RT).
T388 65060-65127 Sentence denotes PBMCs were stained with 50μl of intracellular mix overnight at 4°C.
T389 65128-65243 Sentence denotes The following morning, samples were washed (Perm Buffer, 1800 rpm, 5 min, RT) and further fixed in 50 μl of 4% PFA.
T390 65244-65357 Sentence denotes Prior to acquisition, samples were diluted to 1% PFA and 10,000 counting beads added per sample (BD, Cat#335925).
T391 65358-65392 Sentence denotes Live/dead mix was prepared in PBS.
T392 65393-65531 Sentence denotes For the surface receptor and chemokine staining mix, antibodies were diluted in FACS buffer with 50% BD Brilliant Buffer (BD, Cat#566349).
T393 65532-65577 Sentence denotes Intracellular mix was diluted in Perm Buffer.
T394 65579-65593 Sentence denotes Flow cytometry
T395 65594-65649 Sentence denotes Samples were acquired on a 5 laser BD FACS Symphony A5.
T396 65650-65757 Sentence denotes Standardized SPHERO rainbow beads (Spherotech, Cat#RFP-30-5A) were used to track and adjust PMTs over time.
T397 65758-65833 Sentence denotes UltraComp eBeads (ThermoFisher, Cat#01-2222-42) were used for compensation.
T398 65834-65888 Sentence denotes Up to 2 × 106 live PBMC were acquired per each sample.
T399 65890-65897 Sentence denotes Luminex
T400 65898-65994 Sentence denotes PBMCs from patients were thawed and rested overnight at 37°C in complete RPMI (cRPMI, table S7).
T401 65995-66109 Sentence denotes 96-well flat bottom plates were coated with 1 μg/mL of anti-CD3 (UCHT1, #BE0231, BioXell) in PBS at 4°C overnight.
T402 66110-66195 Sentence denotes The next day, cells were collected and plated at 1 × 105/well in 100 μl in duplicate.
T403 66196-66309 Sentence denotes 2 μg/mL of anti-human CD28/CD49d was added to the wells containing plate-bound anti-CD3 (Clone L293, 347690, BD).
T404 66310-66440 Sentence denotes PBMCs were stimulated or left unstimulated for 16 hours, spun down (1200 rpm, 10 min) and 85 μL/well of supernatant was collected.
T405 66441-66563 Sentence denotes Plasma from matched subjects was thawed on ice, spun (3000 rpm, 1 min) to remove debris, and 85 μl collected in duplicate.
T406 66564-66711 Sentence denotes Luminex assay was run according to manufacturer’s instructions, using a custom human cytokine 31-plex panel (EMD Millipore Corporation, SPRCUS707).
T407 66712-66990 Sentence denotes The panel included: EGF, FGF-2, Eotaxin, sIL-2Ra, G-CSF, GM-CSF, IFN-α2, IFN-γ, IL-10, IL-12P40, IL-12P70, IL-13, IL-15, IL-17A, IL-1Ra, HGF, IL-1β, CXCL9/MIG, IL-2, IL-4, IL-5, IL-6, IL-7, CXCL8/IL-8, CXCL10/IP-10, CCL2/MCP-1, CCL3/MIP-1α, CCL4/MIP-1β, RANTES, TNF-α, and VEGF.
T408 66991-67084 Sentence denotes Assay plates were measured using a Luminex FlexMAP 3D instrument (Thermofisher, Cat#APX1342).
T409 67085-67178 Sentence denotes Data acquisition and analysis were done using xPONENT software www.luminexcorp.com/xponent/).
T410 67179-67237 Sentence denotes Data quality was examined based on the following criteria:
T411 67238-67352 Sentence denotes The standard curve for each analyte has a 5P R2 value > 0.95 with or without minor fitting using xPONENT software.
T412 67353-67544 Sentence denotes To pass assay technical quality control, the results for two controls in the kit needed to be within the 95% of CI (confidence interval) provided by the vendor for >25 of the tested analytes.
T413 67545-67620 Sentence denotes No further tests were done on samples with results out of range low (<OOR).
T414 67621-67795 Sentence denotes Samples with results that were out of range high (>OOR) or greater than the standard curve maximum value (SC max) were not tested at higher dilutions without further request.
T415 67797-67843 Sentence denotes Intracellular stain after CD3/CD28 stimulation
T416 67844-67957 Sentence denotes 96-well flat bottom plates were coated with 1μg/mL of anti-CD3 (UCHT1, #BE0231, BioXell) in PBS at 4°C overnight.
T417 67958-68068 Sentence denotes The next day, cells were collected and plated at 1 × 105/well in 100 μl with 1/1000 of GolgiPlug (BD #555029).
T418 68069-68181 Sentence denotes 2μg/mL of anti-human CD28/CD49d was added to the wells containing plate-bound anti-CD3 (Clone L293, 347690, BD).
T419 68182-68326 Sentence denotes GolgiPlug-treated PBMCs were stimulated or left unstimulated for 16 hours, spun down (1200 rpm, 10 min) and were stained for intracellular IFNɣ.
T420 68328-68376 Sentence denotes Longitudinal analysis D0-D7 and patient grouping
T421 68377-68664 Sentence denotes To identify subjects where the frequency of specific immune cell populations increased, decreased or stayed stable over time (day 0 to day 7), where data was available we used a previously published dataset to establish a standard range of fold change over time in a healthy cohort (44).
T422 68665-68857 Sentence denotes A fold change greater than the mean fold change ± 2 standard deviations was considered an increase, less than this range was considered a decrease, and within this range was considered stable.
T423 68858-68972 Sentence denotes Where this data was not available, a fold change from day 0 to day 7 of between 0.5 and 1.5 was considered stable.
T424 68973-69052 Sentence denotes A fold change <0.5 was considered decreased, and >1.5 was considered increased.
T425 69053-69303 Sentence denotes In order to eliminate redundant tests and maximize statistical power, the pairwise statistical tests shown in Fig. 5G were performed using fold-change as a continuous metric, irrespective of the discrete up/stable/down classification described above.
T426 69304-69536 Sentence denotes Similarly, in fig. S9G, pairwise association tests between changes in UMAP Component coordinates and clinical data were performed using each difference value as a continuous metric, irrespective of the up/stable/down classification.
T427 69538-69581 Sentence denotes Correlation plots and heatmap visualization
T428 69582-69696 Sentence denotes Pairwise correlations between variables were calculated and visualized as a correlogram using R function corrplot.
T429 69697-69885 Sentence denotes Spearman's Rank Correlation coefficient (ρ) was indicated by square size and heat scale; significance indicated by: *p < 0.05, **p < 0.01, and ***p < 0.001; black box indicates FDR < 0.05.
T430 69886-69981 Sentence denotes Heatmaps were created to visualize variable values using R function pheatmap or complexheatmap.
T431 69983-69993 Sentence denotes Statistics
T432 69994-70167 Sentence denotes Due to the heterogeneity of clinical and flow cytometric data, non-parametric tests of association were preferentially used throughout this study unless otherwise specified.
T433 70168-70450 Sentence denotes Correlation coefficients between ordered features (including discrete ordinal, continuous scale, or a mixture of the two) were quantified by the Spearman rank correlation coefficient and significance was assessed by the corresponding non-parametric methods (null hypothesis: ρ = 0).
T434 70451-70651 Sentence denotes Tests of association between mixed continuous versus non-ordered categorical variables were performed by unpaired Wilcoxon test (for n = 2 categories) or by Kruskal-Wallis test (for n > 2 categories).
T435 70652-70728 Sentence denotes Association between categorical variables was assessed by Fisher-exact test.
T436 70729-70930 Sentence denotes For association testing illustrated in heatmaps, categorical variables with more than 2 categories (e.g., ABO blood type) were transformed into binary dummy variables for each category versus the rest.
T437 70931-71045 Sentence denotes All tests were performed two-sided, using a nominal significance threshold of P < 0.05 unless otherwise specified.
T438 71046-71238 Sentence denotes When appropriate to adjust for multiple hypothesis testing, false discovery rate (FDR) correction was performed using the Benjamini-Hochberg procedure at the FDR < 0.05 significance threshold.
T439 71239-71528 Sentence denotes Joint statistical modeling to adjust for confounding of demographic factors (age, sex, and race) when testing for association of UMAP Components 1 and 2 with the NIH Ordinal Severity Scale was performed using ordinal logistic regression provided by the polr function of the R package MASS.
T440 71529-71611 Sentence denotes Statistical analysis of flow cytometry data was performed using R package rstatix.
T441 71612-71703 Sentence denotes Other details, if any, for each experiment are provided within the relevant figure legends.
T442 71705-71758 Sentence denotes High dimensional data analysis of flow cytometry data
T443 71759-71836 Sentence denotes viSNE and FlowSOM analysis were performed on Cytobank (https://cytobank.org).
T444 71837-72066 Sentence denotes B cells, non-naïve CD4 T cells, and non-naïve CD8 T cells were analyzed separately. viSNE analysis was performed using equal sampling of 1000 cells from each FCS file, with 5000 iterations, a perplexity of 30, and a theta of 0.5.
T445 72067-72266 Sentence denotes For B cells, the following markers were used to generate the viSNE maps: CD45RA, IgD, CXCR5, CD138, Eomes, TCF-1, CD38, CD95, CCR7, CD21, KI67, CD27, CX3CR1, CD39, T-bet, HLA-DR, CD16, CD19 and CD20.
T446 72267-72443 Sentence denotes For non-naïve CD4 and CD8 T cells, the following markers were used: CD45RA, PD1, CXCR5, TCF-1, CD38, CD95, Eomes, CCR7, KI67, CD16, CD27, CX3CR1, CD39, CD20, T-bet, and HLA-DR.
T447 72444-72517 Sentence denotes Resulting viSNE maps were fed into the FlowSOM clustering algorithm (59).
T448 72518-72643 Sentence denotes For each cell subset, a new self-organizing map (SOM) was generated using hierarchical consensus clustering on the tSNE axes.
T449 72644-72750 Sentence denotes For each SOM, 225 clusters and 10 or 15 metaclusters were identified for B cells and T cells respectively.
T450 72751-73011 Sentence denotes To group individuals based on B cell landscape, pairwise Earth Mover’s Distance (EMD) value was calculated on the B cell tSNE axes for all COVID-19 day 0 patients, healthy donors, and recovered donors using the emdist package in R as previously described (60).
T451 73012-73089 Sentence denotes Resulting scores were hierarchically clustered using the hclust package in R.
T452 73091-73107 Sentence denotes Batch correction
T453 73108-73196 Sentence denotes During the sample acquisition period, the flow panel was changed to remove one antibody.
T454 73197-73328 Sentence denotes Batch correction was performed for samples acquired before and after this change to remove potential bias from downstream analysis.
T455 73329-73603 Sentence denotes Because the primary flow features were expressed as a fraction of the parent population (falling in the 0-to-1 interval) a variance stabilizing transform (logit) was first applied to each data value, prior to re-centering the second panel to have the same mean as the first.
T456 73604-73715 Sentence denotes After mean-centering, data were transformed back to the original fraction of parent scale by inverse transform.
T457 73716-73828 Sentence denotes This procedure was applied separately to all 553 flow features annotated in the main text and supplemental data.
T458 73829-73953 Sentence denotes Notably, this procedure avoids any batch-corrected feature values artificially falling outside of the original 0 to 1 range.
T459 73954-74107 Sentence denotes Following batch correction, neither UMAP Component 1 nor Component 2 had a statistically significant difference between panels by unpaired Wilcoxon test.
T460 74109-74190 Sentence denotes Visualizing variation of flow cytometric features across the UMAP embedding space
T461 74191-74334 Sentence denotes A feature-weighted kernel density was computed across all COVID-19 patients, and was displayed as a contour plot (Fig. 6G and fig. S8, A to D).
T462 74335-74721 Sentence denotes Whereas traditional kernel density methods apply the same base kernel function to every point to visualize point density, here the base kernel function centered at each individual COVID-19 patient sample was instead weighted (multiplied) by the Z-transform (mean-centered and standard deviation-scaled) of the log-transformed input feature prior to computing the overall kernel density.
T463 74722-74934 Sentence denotes This weighting procedure facilitated visualization of the overall feature gradients (going from relatively low-to-high expression) across UMAP coordinates independent of the different range of each input feature.
T464 74935-75186 Sentence denotes A radially symmetric two-dimensional Gaussian was used as the base kernel function with a variance parameter equal to one-half, which was tuned to be sufficiently broad in order to smooth out local discontinuities and best visualize feature gradients.
T465 75188-75214 Sentence denotes Definition of immunotype 3
T466 75215-75599 Sentence denotes To define COVID-19 patients with low or absent immune responses, classified as immunotype 3, the intersection of the bottom 50% of 5 different flow parameters was used: PB as % of B cells, KI67+ as % of non-naïve CD4 T cells, KI67+ as % of non-naïve CD8 T cells, HLA-DR+CD38+ as % of non-naïve CD4 T cells, HLA-DR+CD38+ as % of non-naïve CD8 T cells—graphically displayed in fig. S10.
T467 75601-75616 Sentence denotes Acknowledgments
T468 75617-75715 Sentence denotes The authors thank patients and blood donors, their families and surrogates, and medical personnel.
T469 75716-75727 Sentence denotes We thank L.
T470 75728-75765 Sentence denotes Bershaw for recruitment of HD and RD.
T471 75766-75777 Sentence denotes We thank S.
T472 75778-75827 Sentence denotes Ngiow for essential infrastructure support and C.
T473 75828-75904 Sentence denotes Ash for donation of computational equipment and design of schematic figures.
T474 75905-75983 Sentence denotes We thank the Wherry lab for discussions and critically reading the manuscript.
T475 75984-75992 Sentence denotes Funding:
T476 75993-76224 Sentence denotes This work was supported by the University of Pennsylvania Institute for Immunology Glick COVID-19 research award (MRB), NIH AI105343, AI082630, and the Allen Institute for Immunology (EJW) and NIH grants HL137006 and H137915 (NJM).
T477 76225-76271 Sentence denotes ACH was funded by grant CA230157 from the NIH.
T478 76272-76310 Sentence denotes DM and JG were funded by T32 CA009140.
T479 76311-76347 Sentence denotes ZC was funded by NIH grant CA234842.
T480 76348-76378 Sentence denotes DAO was funded by NHLBI StARR:
T481 76379-76392 Sentence denotes 1R38HL143613.
T482 76393-76508 Sentence denotes NJM reports funding to her institution from Athersys, Inc., Biomarck, Inc., and the Marcus Foundation for Research.
T483 76509-76567 Sentence denotes JRG is a Cancer Research Institute-Mark Foundation Fellow.
T484 76568-76736 Sentence denotes JRG, JEW, CA, AH, and EJW are supported by the Parker Institute for Cancer Immunotherapy which supports the Cancer Immunology program at the University of Pennsylvania.
T485 76737-76782 Sentence denotes The authors declare no conflicts of interest.
T486 76783-76893 Sentence denotes Author contributions: DM, NJM, MJB, and EJW conceived the project; DM, JRG, AEB, and EJW designed experiments.
T487 76894-77070 Sentence denotes NM conceived the clinical cohort, obtained clinical samples and metadata from COVID-19 patients and provided clinical input; OK and JD provided clinical samples from HD and RD.
T488 77071-77137 Sentence denotes AEB and KD coordinated clinical sample procurement and processing.
T489 77138-77207 Sentence denotes DM, ARG, LKC, MBP, NH, JK, AP, FC, and SFL processed patient samples.
T490 77208-77335 Sentence denotes DM, ZC, and YJH stained and JEW acquired flow cytometry samples; JRG, AEB, and KN performed downstream flow cytometry analysis.
T491 77336-77373 Sentence denotes HR and SCC performed qRT-PCR of PBMC.
T492 77374-77420 Sentence denotes DM, SFL, and FC performed Luminex experiments.
T493 77421-77518 Sentence denotes ECG, EMA, MEW, SG, CPA, MJB, and SEH analyzed COVID-19 patient plasma and provided antibody data.
T494 77519-77653 Sentence denotes ACH and LAV provided additional clinical data; CA compiled and JRG, DO, and CA analyzed clinical metadata with input from ACH and LAV.
T495 77654-77778 Sentence denotes JRG, DAO, SM, and EJW designed data analysis and JRG, ARG, CA, DAO, and SM performed computational and statistical analyses.
T496 77779-77822 Sentence denotes DM, JRG, ARG, CA, and DAO compiled figures.
T497 77823-77886 Sentence denotes LKC, MBP, SA, ACH, LAV, NJM and MB provided intellectual input.
T498 77887-77972 Sentence denotes DM, AEB, ARG, JEW, and EJW wrote the manuscript; all authors reviewed the manuscript.
T499 77973-78130 Sentence denotes Competing interests: E.J.W. has consulting agreements with and/or is on the scientific advisory board for Merck, Roche, Pieris, Elstar, and Surface Oncology.
T500 78131-78195 Sentence denotes E.J.W. is a founder of Surface Oncology and Arsenal Biosciences.
T501 78196-78277 Sentence denotes E.J.W. has a patent licensing agreement on the PD-1 pathway with Roche/Genentech.
T502 78278-78440 Sentence denotes E.J.W. is an inventor on a patent (US Patent number 10,370,446) submitted by Emory University that covers the use of PD-1 blockade to treat infections and cancer.
T503 78441-78473 Sentence denotes Data and materials availability:
T504 78474-78652 Sentence denotes Flow Cytometry data collected in this study was deposited to the Human Pancreas Analysis Program (HPAP-RRID:SCR_016202) Database and Cytobank (61) (https://hpap.pmacs.upenn.edu).
T505 78653-78724 Sentence denotes B cell data (https://premium.cytobank.org/cytobank/experiments/308353).
T506 78725-78806 Sentence denotes Non Naive CD4 T cells (https://premium.cytobank.org/cytobank/experiments/308354).
T507 78807-78888 Sentence denotes Non Naive CD8 T cells (https://premium.cytobank.org/cytobank/experiments/308357).
T508 78889-79110 Sentence denotes This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
T509 79111-79194 Sentence denotes To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
T510 79195-79396 Sentence denotes This license does not apply to figures/photos/artwork or other content included in the article that is credited to a third party; obtain authorization from the rights holder before using such material.
T511 79398-79429 Sentence denotes The UPenn COVID Processing Unit
T512 79430-79451 Sentence denotes Zahidul Alam, Mary M.
T513 79452-79471 Sentence denotes Addison, Katelyn T.
T514 79472-79503 Sentence denotes Byrne, Aditi Chandra, Hélène C.
T515 79504-79542 Sentence denotes Descamps, Yaroslav Kaminskiy, Jacob T.
T516 79543-79577 Sentence denotes Hamilton, Julia Han Noll, Dalia K.
T517 79578-79610 Sentence denotes Omran, Eric Perkey, Elizabeth M.
T518 79611-79644 Sentence denotes Prager, Dana Pueschl, Jennifer B.
T519 79645-79658 Sentence denotes Shah, Jake S.
T520 79659-79676 Sentence denotes Shilan, Ashley N.
T521 79677-79687 Sentence denotes Vanderbeck
T522 79688-79789 Sentence denotes All affiliated with the University of Pennsylvania Perelman School of Medicine Philadelphia, PA, USA.
T523 79791-79814 Sentence denotes Supplementary Materials
T524 79815-79874 Sentence denotes science.sciencemag.org/cgi/content/full/science.abc8511/DC1
T525 79875-79880 Sentence denotes Figs.
T526 79881-79890 Sentence denotes S1 to S11
T527 79891-79905 Sentence denotes Table S1 to S8

2_test

Id Subject Object Predicate Lexical cue
32669297-32346093-135105194 8111-8113 32346093 denotes 31
32669297-32161940-135105195 8869-8870 32161940 denotes 8
32669297-32242950-135105196 8872-8874 32242950 denotes 32
32669297-32217835-135105197 11348-11350 32217835 denotes 17
32669297-32376308-135105197 11348-11350 32376308 denotes 17
32669297-32296069-135105197 11348-11350 32296069 denotes 17
32669297-31986264-135105197 11348-11350 31986264 denotes 17
32669297-27031961-135105198 15033-15035 27031961 denotes 34
32669297-26362266-135105199 15037-15039 26362266 denotes 35
32669297-32267220-135105200 18798-18800 32267220 denotes 27
32669297-32413330-135105201 18802-18804 32413330 denotes 29
32669297-31117010-135105202 18867-18869 31117010 denotes 36
32669297-25172499-135105203 19049-19051 25172499 denotes 38
32669297-32320677-135105204 21419-21421 32320677 denotes 39
32669297-28620653-135105205 21423-21425 28620653 denotes 40
32669297-32303591-135105206 24309-24310 32303591 denotes 2
32669297-32505227-135105207 24312-24313 32505227 denotes 4
32669297-25775592-135105208 27009-27011 25775592 denotes 42
32669297-22238318-135105209 27013-27015 22238318 denotes 43
32669297-28620653-135105210 29966-29968 28620653 denotes 40
32669297-27008164-135105211 32427-32429 27008164 denotes 45
32669297-28397821-135105212 37205-37207 28397821 denotes 46
32669297-18468462-135105213 38594-38596 18468462 denotes 47
32669297-29236685-135105214 38645-38647 29236685 denotes 48
32669297-22286307-135105215 38683-38685 22286307 denotes 49
32669297-26362266-135105216 38713-38715 26362266 denotes 35
32669297-26485519-135105217 48213-48215 26485519 denotes 50
32669297-32203188-135105218 52750-52752 32203188 denotes 12
32669297-32203186-135105218 52750-52752 32203186 denotes 12
32669297-32425950-135105218 52750-52752 32425950 denotes 12
32669297-32085846-135105219 52839-52841 32085846 denotes 52
32669297-32219428-135105220 53149-53151 32219428 denotes 30
32669297-32113510-135105221 53153-53155 32113510 denotes 54
32669297-32219428-135105222 53225-53227 32219428 denotes 30
32669297-27031961-135105223 55977-55979 27031961 denotes 34
32669297-25775592-135105224 55981-55983 25775592 denotes 42
32669297-22238318-135105225 55985-55987 22238318 denotes 43
32669297-15357905-135105226 55989-55991 15357905 denotes 55
32669297-28620653-135105227 56090-56092 28620653 denotes 40
32669297-15357905-135105228 57553-57555 15357905 denotes 55
32669297-18468462-135105229 57840-57842 18468462 denotes 47
32669297-29236685-135105229 57840-57842 29236685 denotes 47
32669297-22286307-135105229 57840-57842 22286307 denotes 47
32669297-22238318-135105230 58000-58002 22238318 denotes 43
32669297-21441455-135105231 58004-58006 21441455 denotes 56
32669297-19843885-135105232 58008-58010 19843885 denotes 57
32669297-32303591-135105233 58351-58352 32303591 denotes 2
32669297-32416070-135105234 60879-60881 32416070 denotes 58
32669297-25573116-135105235 72513-72515 25573116 denotes 59
32669297-30413431-135105236 73007-73009 30413431 denotes 60