PMC:7396557 / 71359-71651 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T706","span":{"begin":33,"end":37},"obj":"NCBITaxon:10088"},{"id":"T707","span":{"begin":92,"end":96},"obj":"NCBITaxon:10088"},{"id":"T708","span":{"begin":115,"end":125},"obj":"GO:0010467"},{"id":"T709","span":{"begin":188,"end":208},"obj":"CHEBI:28874;CHEBI:28874"},{"id":"T710","span":{"begin":219,"end":222},"obj":"PR:000002190"},{"id":"T92701","span":{"begin":33,"end":37},"obj":"NCBITaxon:10088"},{"id":"T11420","span":{"begin":92,"end":96},"obj":"NCBITaxon:10088"},{"id":"T3094","span":{"begin":115,"end":125},"obj":"GO:0010467"},{"id":"T92550","span":{"begin":188,"end":208},"obj":"CHEBI:28874;CHEBI:28874"},{"id":"T57032","span":{"begin":219,"end":222},"obj":"PR:000002190"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T378","span":{"begin":142,"end":151},"obj":"Body_part"},{"id":"T379","span":{"begin":188,"end":208},"obj":"Body_part"}],"attributes":[{"id":"A378","pred":"fma_id","subj":"T378","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A379","pred":"fma_id","subj":"T379","obj":"http://purl.org/sig/ont/fma/fma85436"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T450","span":{"begin":43,"end":47},"obj":"Disease"}],"attributes":[{"id":"A450","pred":"mondo_id","subj":"T450","obj":"http://purl.obolibrary.org/obo/MONDO_0100073"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T659","span":{"begin":9,"end":11},"obj":"http://purl.obolibrary.org/obo/CLO_0001022"},{"id":"T660","span":{"begin":9,"end":11},"obj":"http://purl.obolibrary.org/obo/CLO_0007314"},{"id":"T661","span":{"begin":287,"end":289},"obj":"http://purl.obolibrary.org/obo/CLO_0001022"},{"id":"T662","span":{"begin":287,"end":289},"obj":"http://purl.obolibrary.org/obo/CLO_0007314"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T159","span":{"begin":9,"end":11},"obj":"Chemical"},{"id":"T5160","span":{"begin":166,"end":174},"obj":"Chemical"},{"id":"T56851","span":{"begin":188,"end":208},"obj":"Chemical"},{"id":"T162","span":{"begin":287,"end":289},"obj":"Chemical"}],"attributes":[{"id":"A15664","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_30145"},{"id":"A7865","pred":"chebi_id","subj":"T5160","obj":"http://purl.obolibrary.org/obo/CHEBI_134411"},{"id":"A47515","pred":"chebi_id","subj":"T56851","obj":"http://purl.obolibrary.org/obo/CHEBI_28874"},{"id":"A55853","pred":"chebi_id","subj":"T162","obj":"http://purl.obolibrary.org/obo/CHEBI_30145"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T81","span":{"begin":176,"end":180},"obj":"http://purl.obolibrary.org/obo/GO_0004707"},{"id":"T82","span":{"begin":182,"end":186},"obj":"http://purl.obolibrary.org/obo/GO_0016303"},{"id":"T83","span":{"begin":249,"end":285},"obj":"http://purl.obolibrary.org/obo/GO_0050728"},{"id":"T84","span":{"begin":264,"end":285},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-sentences","denotations":[{"id":"T536","span":{"begin":0,"end":292},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T288","span":{"begin":56,"end":62},"obj":"Phenotype"}],"attributes":[{"id":"A288","pred":"hp_id","subj":"T288","obj":"http://purl.obolibrary.org/obo/HP_0100806"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2048","span":{"begin":219,"end":222},"obj":"Gene"},{"id":"2063","span":{"begin":33,"end":37},"obj":"Species"},{"id":"2064","span":{"begin":92,"end":96},"obj":"Species"},{"id":"2078","span":{"begin":56,"end":62},"obj":"Disease"},{"id":"2079","span":{"begin":83,"end":91},"obj":"Disease"}],"attributes":[{"id":"A2048","pred":"tao:has_database_id","subj":"2048","obj":"Gene:11651"},{"id":"A2063","pred":"tao:has_database_id","subj":"2063","obj":"Tax:10090"},{"id":"A2064","pred":"tao:has_database_id","subj":"2064","obj":"Tax:10090"},{"id":"A2078","pred":"tao:has_database_id","subj":"2078","obj":"MESH:D018805"},{"id":"A2079","pred":"tao:has_database_id","subj":"2079","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Tiantian Li et al. found that in mice with MRSA-induced sepsis, XBJI protected the infected mice by downregulating expression of inflammatory cytokines stimulated by Pam3CSK4, MAPK, PI3K (phosphatidylinositol 3 kinase)/Akt and other pathways, thus, inhibiting the inflammatory response (Li T."}