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PMC:7394275 / 20745-22186 JSONTXT

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LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T307 39-43 SP_10 denotes SARS
T308 109-115 NCBITaxon:4751 denotes fungal
T309 153-161 SP_7 denotes COVID-19
T310 209-213 UBERON:0000104 denotes life
T311 246-254 SP_7 denotes COVID-19
T312 271-285 GO:0010467 denotes overexpression
T313 340-346 UBERON:0002405;GO:0006955 denotes immune
T314 347-355 GO:0006955 denotes response
T315 371-374 PR:000001004 denotes CD4
T316 377-378 CL:0000084 denotes T
T317 389-395 CL:0000084 denotes T cell
T318 437-443 NCBITaxon:4751 denotes fungal
T319 468-476 SP_7 denotes COVID-19
T320 657-663 NCBITaxon:4751 denotes fungal
T321 797-803 CHEBI:37671;CHEBI:37671 denotes glucan
T322 805-818 CHEBI:27680;CHEBI:27680 denotes galactomannan
T323 1130-1138 SP_7 denotes COVID-19
T324 1348-1356 SP_7 denotes COVID-19
T325 1422-1428 NCBITaxon:4751 denotes fungal
T75255 39-43 SP_10 denotes SARS
T39825 109-115 NCBITaxon:4751 denotes fungal
T46069 153-161 SP_7 denotes COVID-19
T64479 209-213 UBERON:0000104 denotes life
T56554 246-254 SP_7 denotes COVID-19
T92048 271-285 GO:0010467 denotes overexpression
T75201 340-346 UBERON:0002405;GO:0006955 denotes immune
T49672 347-355 GO:0006955 denotes response
T2312 371-374 PR:000001004 denotes CD4
T69012 377-378 CL:0000084 denotes T
T54698 389-395 CL:0000084 denotes T cell
T46770 437-443 NCBITaxon:4751 denotes fungal
T58249 468-476 SP_7 denotes COVID-19
T78951 657-663 NCBITaxon:4751 denotes fungal
T3426 797-803 CHEBI:37671;CHEBI:37671 denotes glucan
T20556 805-818 CHEBI:27680;CHEBI:27680 denotes galactomannan
T99766 1130-1138 SP_7 denotes COVID-19
T91168 1348-1356 SP_7 denotes COVID-19
T38663 1422-1428 NCBITaxon:4751 denotes fungal

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T68 302-311 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T69 326-330 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T70 391-395 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
611 1413-1441 Disease denotes invasive fungal co-infection MESH:D060085
638 371-374 Gene denotes CD4 Gene:920
639 383-386 Gene denotes CD8 Gene:925
640 255-263 Species denotes patients Tax:9606
641 477-485 Species denotes patients Tax:9606
642 1139-1147 Species denotes patients Tax:9606
643 1357-1365 Species denotes patients Tax:9606
644 787-803 Chemical denotes (1,3)-β-d-glucan MESH:C480180
645 805-818 Chemical denotes galactomannan MESH:C012990
646 39-43 Disease denotes SARS MESH:D045169
647 116-129 Disease denotes co-infections MESH:D060085
648 153-161 Disease denotes COVID-19 MESH:C000657245
649 226-244 Disease denotes infectious disease MESH:D003141
650 246-254 Disease denotes COVID-19 MESH:C000657245
651 444-456 Disease denotes co-infection MESH:D060085
652 468-476 Disease denotes COVID-19 MESH:C000657245
653 546-557 Disease denotes neutropenia MESH:D009503
654 600-618 Disease denotes immunodeficiencies MESH:D007153
655 624-629 Disease denotes tumor MESH:D009369
656 657-676 Disease denotes fungal co-infection MESH:D060085
657 899-915 Disease denotes invasive mycosis MESH:D015821
658 983-999 Disease denotes invasive mycosis MESH:D015821
659 1130-1138 Disease denotes COVID-19 MESH:C000657245
660 1268-1281 Disease denotes aspergillosis MESH:D001228
661 1283-1294 Disease denotes candidiasis MESH:D002177
662 1313-1327 Disease denotes cryptococcosis MESH:D003453
663 1348-1356 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T186 39-43 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T187 48-57 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T188 119-129 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T189 153-161 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T190 226-244 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T191 246-254 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T192 447-456 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T193 468-476 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T194 546-557 Disease denotes neutropenia http://purl.obolibrary.org/obo/MONDO_0001475
T195 591-618 Disease denotes acquired immunodeficiencies http://purl.obolibrary.org/obo/MONDO_0017769
T196 624-629 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T197 667-676 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T198 908-915 Disease denotes mycosis http://purl.obolibrary.org/obo/MONDO_0002041
T199 992-999 Disease denotes mycosis http://purl.obolibrary.org/obo/MONDO_0002041
T200 1130-1138 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T201 1268-1281 Disease denotes aspergillosis http://purl.obolibrary.org/obo/MONDO_0005657
T202 1283-1294 Disease denotes candidiasis http://purl.obolibrary.org/obo/MONDO_0002026
T203 1296-1308 Disease denotes mucormycosis http://purl.obolibrary.org/obo/MONDO_0019136
T204 1313-1327 Disease denotes cryptococcosis http://purl.obolibrary.org/obo/MONDO_0005724
T205 1348-1356 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T206 1432-1441 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T128 207-208 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T129 326-330 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T130 371-374 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T131 383-386 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T132 389-395 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T133 1166-1167 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T128 565-567 Chemical denotes GC http://purl.obolibrary.org/obo/CHEBI_73890
T129 797-803 Chemical denotes glucan http://purl.obolibrary.org/obo/CHEBI_37163
T130 805-818 Chemical denotes galactomannan http://purl.obolibrary.org/obo/CHEBI_27680

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T6 326-355 http://purl.obolibrary.org/obo/GO_0002443 denotes cell-mediated immune response
T7 340-355 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T5 805-818 GlycoEpitope denotes galactomannan http://www.glycoepitope.jp/epitopes/EP0510

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T105 0-194 Sentence denotes By analyzing retrospective analysis of SARS and influenza data from China and worldwide, we surmise that the fungal co-infections associated with global COVID-19 might be missed or misdiagnosed.
T106 195-457 Sentence denotes Further, as a life-threatening infectious disease, COVID-19 patients showed overexpression of inflammatory cytokines, and impaired cell-mediated immune response with decreased CD4 + T and CD8 + T cell counts, indicating its susceptibility to fungal co-infection.
T107 458-677 Sentence denotes Moreover, COVID-19 patients accompanied with immunocompromised state, such as prolonged neutropenia, HSCT, GC use, SOT, inherited or acquired immunodeficiencies, and tumor are more likely to develop fungal co-infection.
T108 678-916 Sentence denotes Here, we summarized updated diagnostic information (histopathology, direct microscopic examination, culture, (1,3)-β-d-glucan, galactomannan, PCR-based assays, MALDI-TOF technology, etc.) and treatment recommendations of invasive mycosis.
T109 917-1148 Sentence denotes We suggest it is prudent to assess the risk factors, the types of invasive mycosis, the strengths and limitations of diagnostic methods, clinical settings, and the need for standard or individualized treatment in COVID-19 patients.
T110 1149-1366 Sentence denotes Finally, provide a clinical flow diagram (Fig. 1) to assist the clinicians and laboratory experts in the management of aspergillosis, candidiasis, mucormycosis, or cryptococcosis as comorbidities in COVID-19 patients.
T111 1367-1441 Sentence denotes Fig. 1 Diagnostic and therapeutic pathway for invasive fungal co-infection

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T20 546-557 Phenotype denotes neutropenia http://purl.obolibrary.org/obo/HP_0001875
T21 600-618 Phenotype denotes immunodeficiencies http://purl.obolibrary.org/obo/HP_0002721
T22 624-629 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664