PMC:7394275 / 1412-2593 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T20","span":{"begin":7,"end":12},"obj":"SP_6;NCBITaxon:9606"},{"id":"T21","span":{"begin":16,"end":21},"obj":"SP_6;NCBITaxon:9606"},{"id":"T22","span":{"begin":43,"end":54},"obj":"NCBITaxon:11118"},{"id":"T23","span":{"begin":69,"end":77},"obj":"SP_7"},{"id":"T24","span":{"begin":90,"end":102},"obj":"SP_7"},{"id":"T25","span":{"begin":103,"end":114},"obj":"SP_7;UBERON:0001004"},{"id":"T26","span":{"begin":115,"end":137},"obj":"SP_7"},{"id":"T27","span":{"begin":139,"end":149},"obj":"SP_7"},{"id":"T28","span":{"begin":235,"end":243},"obj":"SP_7"},{"id":"T29","span":{"begin":357,"end":363},"obj":"GO:0016265"},{"id":"T30","span":{"begin":379,"end":387},"obj":"SP_10"},{"id":"T31","span":{"begin":392,"end":436},"obj":"SP_9"},{"id":"T32","span":{"begin":438,"end":446},"obj":"SP_9"},{"id":"T33","span":{"begin":449,"end":459},"obj":"SP_7"},{"id":"T34","span":{"begin":485,"end":496},"obj":"UBERON:0001004"},{"id":"T35","span":{"begin":591,"end":599},"obj":"UBERON:0003215"},{"id":"T36","span":{"begin":643,"end":651},"obj":"SP_7"},{"id":"T37","span":{"begin":673,"end":690},"obj":"CHEBI:35705;CHEBI:35705"},{"id":"T38","span":{"begin":710,"end":713},"obj":"PR:000001004"},{"id":"T39","span":{"begin":728,"end":735},"obj":"CL:0000084"},{"id":"T40","span":{"begin":815,"end":834},"obj":"UBERON:0007221"},{"id":"T41","span":{"begin":975,"end":981},"obj":"NCBITaxon:4751"},{"id":"T42","span":{"begin":1039,"end":1047},"obj":"SP_7"},{"id":"T43","span":{"begin":1077,"end":1083},"obj":"NCBITaxon:4751"},{"id":"T87926","span":{"begin":7,"end":12},"obj":"SP_6;NCBITaxon:9606"},{"id":"T44317","span":{"begin":16,"end":21},"obj":"SP_6;NCBITaxon:9606"},{"id":"T51260","span":{"begin":43,"end":54},"obj":"NCBITaxon:11118"},{"id":"T60002","span":{"begin":69,"end":77},"obj":"SP_7"},{"id":"T53048","span":{"begin":90,"end":102},"obj":"SP_7"},{"id":"T10983","span":{"begin":103,"end":114},"obj":"SP_7;UBERON:0001004"},{"id":"T18020","span":{"begin":115,"end":137},"obj":"SP_7"},{"id":"T39408","span":{"begin":139,"end":149},"obj":"SP_7"},{"id":"T58688","span":{"begin":235,"end":243},"obj":"SP_7"},{"id":"T97901","span":{"begin":357,"end":363},"obj":"GO:0016265"},{"id":"T15306","span":{"begin":379,"end":387},"obj":"SP_10"},{"id":"T84834","span":{"begin":392,"end":436},"obj":"SP_9"},{"id":"T47132","span":{"begin":438,"end":446},"obj":"SP_9"},{"id":"T93587","span":{"begin":449,"end":459},"obj":"SP_7"},{"id":"T30768","span":{"begin":485,"end":496},"obj":"UBERON:0001004"},{"id":"T38817","span":{"begin":591,"end":599},"obj":"UBERON:0003215"},{"id":"T68441","span":{"begin":643,"end":651},"obj":"SP_7"},{"id":"T85434","span":{"begin":673,"end":690},"obj":"CHEBI:35705;CHEBI:35705"},{"id":"T96661","span":{"begin":710,"end":713},"obj":"PR:000001004"},{"id":"T91572","span":{"begin":728,"end":735},"obj":"CL:0000084"},{"id":"T27673","span":{"begin":815,"end":834},"obj":"UBERON:0007221"},{"id":"T544","span":{"begin":975,"end":981},"obj":"NCBITaxon:4751"},{"id":"T63230","span":{"begin":1039,"end":1047},"obj":"SP_7"},{"id":"T67064","span":{"begin":1077,"end":1083},"obj":"NCBITaxon:4751"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":591,"end":599},"obj":"Body_part"},{"id":"T2","span":{"begin":730,"end":735},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma264783"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"81","span":{"begin":710,"end":713},"obj":"Gene"},{"id":"82","span":{"begin":722,"end":725},"obj":"Gene"},{"id":"83","span":{"begin":7,"end":12},"obj":"Species"},{"id":"84","span":{"begin":16,"end":21},"obj":"Species"},{"id":"85","span":{"begin":90,"end":137},"obj":"Species"},{"id":"86","span":{"begin":139,"end":149},"obj":"Species"},{"id":"87","span":{"begin":379,"end":387},"obj":"Species"},{"id":"88","span":{"begin":392,"end":447},"obj":"Species"},{"id":"89","span":{"begin":449,"end":459},"obj":"Species"},{"id":"90","span":{"begin":652,"end":660},"obj":"Species"},{"id":"91","span":{"begin":756,"end":764},"obj":"Species"},{"id":"92","span":{"begin":781,"end":789},"obj":"Species"},{"id":"93","span":{"begin":1048,"end":1056},"obj":"Species"},{"id":"94","span":{"begin":43,"end":67},"obj":"Disease"},{"id":"95","span":{"begin":69,"end":77},"obj":"Disease"},{"id":"96","span":{"begin":235,"end":243},"obj":"Disease"},{"id":"97","span":{"begin":357,"end":363},"obj":"Disease"},{"id":"98","span":{"begin":485,"end":506},"obj":"Disease"},{"id":"99","span":{"begin":521,"end":557},"obj":"Disease"},{"id":"100","span":{"begin":559,"end":563},"obj":"Disease"},{"id":"101","span":{"begin":643,"end":651},"obj":"Disease"},{"id":"102","span":{"begin":741,"end":755},"obj":"Disease"},{"id":"103","span":{"begin":982,"end":995},"obj":"Disease"},{"id":"104","span":{"begin":1039,"end":1047},"obj":"Disease"},{"id":"105","span":{"begin":1084,"end":1094},"obj":"Disease"}],"attributes":[{"id":"A81","pred":"tao:has_database_id","subj":"81","obj":"Gene:920"},{"id":"A82","pred":"tao:has_database_id","subj":"82","obj":"Gene:925"},{"id":"A83","pred":"tao:has_database_id","subj":"83","obj":"Tax:9606"},{"id":"A84","pred":"tao:has_database_id","subj":"84","obj":"Tax:9606"},{"id":"A85","pred":"tao:has_database_id","subj":"85","obj":"Tax:2697049"},{"id":"A86","pred":"tao:has_database_id","subj":"86","obj":"Tax:2697049"},{"id":"A87","pred":"tao:has_database_id","subj":"87","obj":"Tax:694009"},{"id":"A88","pred":"tao:has_database_id","subj":"88","obj":"Tax:1335626"},{"id":"A89","pred":"tao:has_database_id","subj":"89","obj":"Tax:2697049"},{"id":"A90","pred":"tao:has_database_id","subj":"90","obj":"Tax:9606"},{"id":"A91","pred":"tao:has_database_id","subj":"91","obj":"Tax:9606"},{"id":"A92","pred":"tao:has_database_id","subj":"92","obj":"Tax:9606"},{"id":"A93","pred":"tao:has_database_id","subj":"93","obj":"Tax:9606"},{"id":"A94","pred":"tao:has_database_id","subj":"94","obj":"MESH:C000657245"},{"id":"A95","pred":"tao:has_database_id","subj":"95","obj":"MESH:C000657245"},{"id":"A96","pred":"tao:has_database_id","subj":"96","obj":"MESH:C000657245"},{"id":"A97","pred":"tao:has_database_id","subj":"97","obj":"MESH:D003643"},{"id":"A98","pred":"tao:has_database_id","subj":"98","obj":"MESH:D012141"},{"id":"A99","pred":"tao:has_database_id","subj":"99","obj":"MESH:D012128"},{"id":"A100","pred":"tao:has_database_id","subj":"100","obj":"MESH:D012128"},{"id":"A101","pred":"tao:has_database_id","subj":"101","obj":"MESH:C000657245"},{"id":"A102","pred":"tao:has_database_id","subj":"102","obj":"MESH:D016638"},{"id":"A103","pred":"tao:has_database_id","subj":"103","obj":"MESH:D060085"},{"id":"A104","pred":"tao:has_database_id","subj":"104","obj":"MESH:C000657245"},{"id":"A105","pred":"tao:has_database_id","subj":"105","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T25","span":{"begin":43,"end":67},"obj":"Disease"},{"id":"T26","span":{"begin":69,"end":77},"obj":"Disease"},{"id":"T27","span":{"begin":90,"end":137},"obj":"Disease"},{"id":"T28","span":{"begin":90,"end":123},"obj":"Disease"},{"id":"T29","span":{"begin":139,"end":147},"obj":"Disease"},{"id":"T30","span":{"begin":235,"end":243},"obj":"Disease"},{"id":"T31","span":{"begin":379,"end":387},"obj":"Disease"},{"id":"T32","span":{"begin":449,"end":457},"obj":"Disease"},{"id":"T33","span":{"begin":485,"end":506},"obj":"Disease"},{"id":"T34","span":{"begin":497,"end":506},"obj":"Disease"},{"id":"T35","span":{"begin":521,"end":557},"obj":"Disease"},{"id":"T36","span":{"begin":527,"end":557},"obj":"Disease"},{"id":"T37","span":{"begin":559,"end":563},"obj":"Disease"},{"id":"T38","span":{"begin":643,"end":651},"obj":"Disease"},{"id":"T39","span":{"begin":985,"end":995},"obj":"Disease"},{"id":"T40","span":{"begin":1039,"end":1047},"obj":"Disease"},{"id":"T41","span":{"begin":1077,"end":1094},"obj":"Disease"}],"attributes":[{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A33","pred":"mondo_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/MONDO_0024355"},{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0002041"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T7","span":{"begin":7,"end":12},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T8","span":{"begin":16,"end":21},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T9","span":{"begin":152,"end":155},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T10","span":{"begin":244,"end":247},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T11","span":{"begin":696,"end":697},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T12","span":{"begin":710,"end":713},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T13","span":{"begin":722,"end":725},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T14","span":{"begin":728,"end":735},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T15","span":{"begin":885,"end":886},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T11","span":{"begin":0,"end":209},"obj":"Sentence"},{"id":"T12","span":{"begin":210,"end":373},"obj":"Sentence"},{"id":"T13","span":{"begin":374,"end":569},"obj":"Sentence"},{"id":"T14","span":{"begin":570,"end":740},"obj":"Sentence"},{"id":"T15","span":{"begin":741,"end":1000},"obj":"Sentence"},{"id":"T16","span":{"begin":1001,"end":1181},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":485,"end":506},"obj":"Phenotype"},{"id":"T2","span":{"begin":527,"end":547},"obj":"Phenotype"},{"id":"T3","span":{"begin":583,"end":606},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0011947"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0033006"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}

{"project":"2_test","denotations":[{"id":"32737747-32015507-73473585","span":{"begin":203,"end":204},"obj":"32015507"},{"id":"32737747-32123347-73473586","span":{"begin":206,"end":207},"obj":"32123347"},{"id":"32737747-32910461-73473587","span":{"begin":566,"end":567},"obj":"32910461"},{"id":"32737747-32731000-73473588","span":{"begin":737,"end":738},"obj":"32731000"},{"id":"32737747-32598906-73473589","span":{"begin":997,"end":998},"obj":"32598906"},{"id":"32737747-32334948-73473590","span":{"begin":1178,"end":1179},"obj":"32334948"}],"text":"As the human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been an emergency global public health events [1, 2]. Till May 18th, 2020, the COVID-19 has rapidly spread to 212 countries and caused nearly 5 million laboratory-confirmed cases and more than 310,000 deaths globally. Like SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS-CoV-2 is responsible for lower respiratory infection and can cause Acute Respiratory Distress Syndromes (ARDS) [3]. Besides, the diffuse alveolar damage with severe inflammatory exudation, COVID-19 patients always have immunosuppression with a decrease in CD4 + T and CD8 + T cells [4]. Critically ill patients, especially the patients who were admitted to the intensive care unit (ICU) and required mechanical ventilation, or had a longer duration of hospital stays, even as long as 50 days, were more likely to develop fungal co-infections [5]. Hence, it is important to notice that COVID-19 patients can develop further fungal infections during the middle and latter stages of this disease, especially severely ill ones [6]."}