PMC:7388103 / 9669-10417 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T63","span":{"begin":552,"end":560},"obj":"Body_part"}],"attributes":[{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma62851"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T116","span":{"begin":168,"end":170},"obj":"Disease"},{"id":"T117","span":{"begin":193,"end":195},"obj":"Disease"},{"id":"T118","span":{"begin":245,"end":248},"obj":"Disease"},{"id":"T119","span":{"begin":271,"end":273},"obj":"Disease"},{"id":"T120","span":{"begin":330,"end":333},"obj":"Disease"},{"id":"T121","span":{"begin":386,"end":388},"obj":"Disease"},{"id":"T122","span":{"begin":463,"end":466},"obj":"Disease"},{"id":"T123","span":{"begin":641,"end":644},"obj":"Disease"}],"attributes":[{"id":"A116","pred":"mondo_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A117","pred":"mondo_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0018048"},{"id":"A119","pred":"mondo_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A120","pred":"mondo_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/MONDO_0018048"},{"id":"A121","pred":"mondo_id","subj":"T121","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A122","pred":"mondo_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/MONDO_0018048"},{"id":"A123","pred":"mondo_id","subj":"T123","obj":"http://purl.obolibrary.org/obo/MONDO_0018048"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T96","span":{"begin":217,"end":218},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T97","span":{"begin":344,"end":345},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T98","span":{"begin":397,"end":398},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T99","span":{"begin":537,"end":542},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T100","span":{"begin":561,"end":571},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T101","span":{"begin":591,"end":592},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T102","span":{"begin":661,"end":662},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T103","span":{"begin":673,"end":677},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T15","span":{"begin":552,"end":571},"obj":"http://purl.obolibrary.org/obo/GO_0030168"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"LitCovid-sentences","denotations":[{"id":"T78","span":{"begin":0,"end":367},"obj":"Sentence"},{"id":"T79","span":{"begin":368,"end":748},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T82","span":{"begin":245,"end":248},"obj":"Phenotype"},{"id":"T83","span":{"begin":330,"end":333},"obj":"Phenotype"},{"id":"T84","span":{"begin":463,"end":466},"obj":"Phenotype"},{"id":"T85","span":{"begin":641,"end":644},"obj":"Phenotype"}],"attributes":[{"id":"A82","pred":"hp_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/HP_0011874"},{"id":"A83","pred":"hp_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/HP_0011874"},{"id":"A84","pred":"hp_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/HP_0011874"},{"id":"A85","pred":"hp_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/HP_0011874"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"LitCovid-PubTator","denotations":[{"id":"415","span":{"begin":368,"end":376},"obj":"Species"},{"id":"416","span":{"begin":245,"end":248},"obj":"Disease"},{"id":"417","span":{"begin":330,"end":333},"obj":"Disease"},{"id":"418","span":{"begin":463,"end":466},"obj":"Disease"},{"id":"419","span":{"begin":641,"end":644},"obj":"Disease"}],"attributes":[{"id":"A415","pred":"tao:has_database_id","subj":"415","obj":"Tax:9606"},{"id":"A416","pred":"tao:has_database_id","subj":"416","obj":"MESH:D013921"},{"id":"A417","pred":"tao:has_database_id","subj":"417","obj":"MESH:D013921"},{"id":"A418","pred":"tao:has_database_id","subj":"418","obj":"MESH:D013921"},{"id":"A419","pred":"tao:has_database_id","subj":"419","obj":"MESH:D013921"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}

{"project":"2_test","denotations":[{"id":"32720827-22195526-61488868","span":{"begin":75,"end":77},"obj":"22195526"},{"id":"32720827-22195526-61488869","span":{"begin":180,"end":182},"obj":"22195526"},{"id":"32720827-18489711-61488870","span":{"begin":183,"end":185},"obj":"18489711"},{"id":"32720827-22195526-61488871","span":{"begin":249,"end":251},"obj":"22195526"},{"id":"32720827-22195526-61488872","span":{"begin":434,"end":436},"obj":"22195526"},{"id":"32720827-18489711-61488873","span":{"begin":437,"end":439},"obj":"18489711"},{"id":"32720827-22990018-61488874","span":{"begin":746,"end":748},"obj":"22990018"}],"text":"Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA). Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13"}