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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T27 143-150 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T28 143-150 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T29 282-289 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T30 282-289 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T31 304-311 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T32 304-311 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T33 1387-1394 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T34 1387-1394 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T35 1406-1413 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T36 1406-1413 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T37 1446-1453 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T38 1446-1453 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T39 3950-3957 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T40 3950-3957 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T41 4189-4196 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T42 4189-4196 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T43 4685-4692 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T44 4685-4692 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T45 4747-4754 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T46 4747-4754 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T45 65-73 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T46 143-150 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T47 198-206 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T48 218-221 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T49 282-289 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T50 296-299 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T51 304-311 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T52 361-370 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T53 375-384 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T54 418-427 Body_part denotes platelets http://purl.org/sig/ont/fma/fma62851
T55 432-441 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T56 999-1007 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T57 1275-1283 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T58 1387-1394 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T59 1406-1413 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T60 1446-1453 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T61 2464-2468 Body_part denotes limb http://purl.org/sig/ont/fma/fma7182
T62 2656-2664 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T63 3721-3729 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T64 3950-3957 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T65 4189-4196 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T66 4685-4692 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T67 4747-4754 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T12 2464-2468 Body_part denotes limb http://purl.obolibrary.org/obo/UBERON_0002101

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T79 11-14 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T80 163-181 Disease denotes hypercoagulability http://purl.obolibrary.org/obo/MONDO_0002305
T81 515-518 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T82 722-725 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T83 790-793 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T84 812-834 Disease denotes venous thromboembolism http://purl.obolibrary.org/obo/MONDO_0005399
T85 844-860 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T86 916-919 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T87 925-935 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T88 965-975 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T89 1129-1132 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T90 1219-1222 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T91 1372-1375 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T92 1831-1834 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T93 1878-1881 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T94 1959-1969 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T95 2230-2254 Disease denotes consumptive coagulopathy http://purl.obolibrary.org/obo/MONDO_0001243
T96 2242-2254 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T97 2275-2283 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T98 2394-2399 Disease denotes lupus http://purl.obolibrary.org/obo/MONDO_0004670
T99 2449-2459 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831
T100 2569-2572 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T101 2596-2599 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T102 2720-2723 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T103 2727-2752 Disease denotes Antiphospholipid syndrome http://purl.obolibrary.org/obo/MONDO_0007140
T104 2774-2782 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 2845-2848 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T106 2880-2883 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T107 2921-2937 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T108 2989-2992 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T109 3021-3037 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T110 3061-3085 Disease denotes consumptive coagulopathy http://purl.obolibrary.org/obo/MONDO_0001243
T111 3073-3085 Disease denotes coagulopathy http://purl.obolibrary.org/obo/MONDO_0001531
T112 3093-3096 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T113 3105-3123 Disease denotes pulmonary embolism http://purl.obolibrary.org/obo/MONDO_0005279
T114 3128-3166 Disease denotes catastrophic antiphospholipid syndrome http://purl.obolibrary.org/obo/MONDO_0018737
T115 3141-3166 Disease denotes antiphospholipid syndrome http://purl.obolibrary.org/obo/MONDO_0007140
T116 3337-3339 Disease denotes OD http://purl.obolibrary.org/obo/MONDO_0017178
T117 3362-3364 Disease denotes OD http://purl.obolibrary.org/obo/MONDO_0017178
T118 3414-3417 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T119 3440-3442 Disease denotes OD http://purl.obolibrary.org/obo/MONDO_0017178
T120 3499-3502 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T121 3555-3557 Disease denotes OD http://purl.obolibrary.org/obo/MONDO_0017178
T122 3632-3635 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T123 3810-3813 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T124 3997-4005 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T125 4029-4032 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T126 4043-4045 Disease denotes OD http://purl.obolibrary.org/obo/MONDO_0017178
T127 4157-4165 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 4360-4368 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T129 4377-4399 Disease denotes venous thromboembolism http://purl.obolibrary.org/obo/MONDO_0005399
T130 4468-4471 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T131 4491-4494 Disease denotes HIT http://purl.obolibrary.org/obo/MONDO_0018048
T132 4650-4660 Disease denotes thrombosis http://purl.obolibrary.org/obo/MONDO_0000831

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T75 207-217 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T76 375-384 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T77 389-397 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T78 404-414 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activation
T79 432-441 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T80 588-589 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T81 888-889 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 1191-1198 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T83 1284-1294 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T84 1440-1441 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 1655-1656 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 1699-1700 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 1740-1741 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 2010-2011 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T89 2361-2362 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 2464-2468 http://www.ebi.ac.uk/efo/EFO_0000876 denotes limb
T91 2577-2578 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T92 2665-2675 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T93 2753-2756 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T94 2792-2794 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T95 2820-2824 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T96 3386-3387 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 3513-3514 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 3566-3567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 3706-3711 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T100 3730-3740 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T101 3760-3761 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T102 3830-3831 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 3842-3846 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T104 4231-4232 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 4255-4259 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T106 4456-4463 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T107 4473-4474 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T108 4626-4627 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T38 143-150 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T39 282-289 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T40 304-311 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T41 1387-1394 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T42 1406-1413 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T43 1446-1453 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T44 1454-1467 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T45 1601-1611 Chemical denotes argatroban http://purl.obolibrary.org/obo/CHEBI_48720
T46 1613-1624 Chemical denotes bivalirudin http://purl.obolibrary.org/obo/CHEBI_59173
T47 1638-1650 Chemical denotes fondaparinux http://purl.obolibrary.org/obo/CHEBI_61033
T48 1669-1682 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T49 1712-1721 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T50 1883-1893 Chemical denotes argatroban http://purl.obolibrary.org/obo/CHEBI_48720
T51 2031-2041 Chemical denotes argatroban http://purl.obolibrary.org/obo/CHEBI_48720
T52 2220-2228 Chemical denotes warfarin http://purl.obolibrary.org/obo/CHEBI_10033
T53 2375-2384 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T54 2400-2413 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T55 2507-2517 Chemical denotes argatroban http://purl.obolibrary.org/obo/CHEBI_48720
T56 3950-3957 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T57 4189-4196 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T58 4437-4440 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092
T60 4543-4557 Chemical denotes anticoagulants http://purl.obolibrary.org/obo/CHEBI_50249
T61 4685-4692 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T62 4747-4754 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T12 198-217 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet-activating
T13 1275-1294 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet activation
T14 2656-2675 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet-activating
T15 3721-3740 http://purl.obolibrary.org/obo/GO_0030168 denotes platelet activation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T67 0-10 Sentence denotes Discussion
T68 11-403 Sentence denotes HIT is an immune-mediated condition, characterized by platelet drop of 50% or greater, typically within 5 to 10 days of exposure to heparin, leading to hypercoagulability and presence of platelet-activating IgG antibodies.4-6 These antibodies target complexes of PF4 and heparin.6 The IgG-PF4-heparin immune complexes cross-link Fcy (γ) receptors on platelets and monocytes and activate them.
T69 404-514 Sentence denotes Activation of platelets and monocytes increases thrombin generation, leading to thromboembolic complications.4
T70 515-884 Sentence denotes HIT affects 1 in 5000 hospitalized patients and paradoxically results in a prothrombotic state and usually does not induce bleeding.4 Thromboembolic phenomena are seen in half of the patients with confirmed HIT.4 The mortality rate is around 5% and 10%.6 In our patient with HIT, the diagnosis of venous thromboembolism preceded thrombocytopenia, which is not uncommon.
T71 885-1016 Sentence denotes In a series of 408 patients of HIT with thrombosis, 33.5% of patients developed thrombosis before the decrease in platelet counts.7
T72 1017-1305 Sentence denotes American Society of Hematology guidelines recommends the use of 4T score to estimate the pretest probability of HIT.6 In those with intermediate or high pretest probability, testing for the presence of HIT antibodies should be done, by using immunoassays or platelet activation assays.4,5
T73 1306-1785 Sentence denotes The first step in the management of highly suspected or confirmed HIT is to stop heparin (including heparin flushes), and to initiate a non-heparin anticoagulant, to prevent thrombotic events, in the setting of ongoing massive thrombin generation.4 Available options for anticoagulation include argatroban, bivalirudin, danaparoid, fondaparinux, or a direct oral anticoagulant.6 Argatroban is a reversible inhibitor of thrombin5 with a short half-life and is not renally cleared.
T74 1786-2474 Sentence denotes It is commonly used in the United States for HIT.4 In 2 multicenter trials of patients with HIT, argatroban resulted in reduced composite endpoint of death, amputation, and thrombosis, when compared with historic controls.5 A major concern with argatroban is potential under-anticoagulation in patients with elevated partial thromboplastin time, secondary to additional coagulopathies (hepatic dysfunction, prior anticoagulation with warfarin, consumptive coagulopathy, and more recently, COVID-19).4 Partial thromboplastin time confounding may also occur in the presence of a nonspecific inhibitor (such as lupus anticoagulant).8 This would increase the risk of thrombosis and limb loss.
T75 2475-2576 Sentence denotes Data supporting the efficacy of argatroban is limited to patients with suspected or confirmed HIT.8,9
T76 2577-2621 Sentence denotes A major problem of HIT is its overdiagnosis.
T77 2622-3168 Sentence denotes Only around 50% of EIA+ sera have platelet-activating properties and, therefore, do not have true HIT.10 Antiphospholipid syndrome has been reported in COVID-19 patients,11 and these patients often test false positive with HIT serology.9 In the ICU setting, HIT explains about 1 out of 100 cases of thrombocytopenia.8 Critically ill patients have other plausible non-HIT mechanisms to explain their thrombocytopenia, including septicemia, consumptive coagulopathy in non-HIT-related pulmonary embolism, or catastrophic antiphospholipid syndrome.8
T78 3169-3536 Sentence denotes Many laboratories report EIA results qualitatively as positive or negative.10 Interpretation of this immunoassay is improved with quantitative reporting in the form of OD levels.1,10,12 Higher OD levels correspond to a higher likelihood of true HIT.10 Weak-positive EIA (OD 0.4 to 1 unit) points strongly against the diagnosis of HIT (≤5% have a strong-positive SRA).
T79 3537-3917 Sentence denotes Patients with EIA OD ≥2 have a ~90% chance of strong-positive SRA.10,12 Accuracy of diagnosing HIT is significantly improved by combining an immunoassay with functional tests, such as platelet activation assays (eg, SRA).4 A negative functional assay essentially rules out HIT.4 Often, SRA is a “send-out test” and results are unavailable to assist with initial decision making.13
T80 3918-4033 Sentence denotes Liu et al14 suggested that anti-heparin-PF4 antibodies are induced in critical COVID-19 patients, resulting in HIT.
T81 4034-4125 Sentence denotes However, OD analysis and SRA were not performed in these patients due to limited resources.
T82 4126-4212 Sentence denotes Our 4 additional patients with COVID-19 were positive for anti-heparin PF4 antibodies.
T83 4213-4260 Sentence denotes However, they had a negative confirmatory test.
T84 4261-4472 Sentence denotes Perhaps, their intermediate to high pretest probabilities was partly related to complications from COVID-19 itself (venous thromboembolism, sepsis, multiorgan dysfunction, and DIC), which led to testing for HIT.
T85 4473-4757 Sentence denotes A misdiagnosis of HIT could potentially lead to exposure to alternate anticoagulants with risks of major hemorrhage, nonavailability of reversal agents, a potential increase in thrombosis from discontinuation of heparin, and increased medical expenditure when compared with heparin.13

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T53 11-14 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T54 163-181 Phenotype denotes hypercoagulability http://purl.obolibrary.org/obo/HP_0100724
T55 484-498 Phenotype denotes thromboembolic http://purl.obolibrary.org/obo/HP_0001907
T56 515-518 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T57 649-663 Phenotype denotes Thromboembolic http://purl.obolibrary.org/obo/HP_0001907
T58 722-725 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T59 790-793 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T60 819-834 Phenotype denotes thromboembolism http://purl.obolibrary.org/obo/HP_0001907
T61 844-860 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T62 916-919 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T63 1129-1132 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T64 1219-1222 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T65 1372-1375 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T66 1831-1834 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T67 1878-1881 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T68 2156-2170 Phenotype denotes coagulopathies http://purl.obolibrary.org/obo/HP_0003256
T69 2242-2254 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T70 2394-2413 Phenotype denotes lupus anticoagulant http://purl.obolibrary.org/obo/HP_0025343
T71 2569-2572 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T72 2596-2599 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T73 2720-2723 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T74 2845-2848 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T75 2880-2883 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T76 2921-2937 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T77 2989-2992 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T78 3021-3037 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T79 3073-3085 Phenotype denotes coagulopathy http://purl.obolibrary.org/obo/HP_0003256
T80 3093-3096 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T81 3105-3123 Phenotype denotes pulmonary embolism http://purl.obolibrary.org/obo/HP_0002204
T82 3414-3417 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T83 3499-3502 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T84 3632-3635 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T85 3810-3813 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T86 4029-4032 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T87 4384-4399 Phenotype denotes thromboembolism http://purl.obolibrary.org/obo/HP_0001907
T88 4401-4407 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T89 4437-4440 Phenotype denotes DIC http://purl.obolibrary.org/obo/HP_0005521
T90 4468-4471 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874
T91 4491-4494 Phenotype denotes HIT http://purl.obolibrary.org/obo/HP_0011874

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
273 274-277 Gene denotes PF4 Gene:5196
274 452-460 Gene denotes thrombin Gene:2147
275 300-303 Gene denotes PF4 Gene:5196
276 143-150 Chemical denotes heparin MESH:D006493
277 282-289 Chemical denotes heparin MESH:D006493
278 304-311 Chemical denotes heparin MESH:D006493
279 11-14 Disease denotes HIT MESH:D013921
280 163-181 Disease denotes hypercoagulability MESH:D019851
281 484-512 Disease denotes thromboembolic complications MESH:D013923
298 550-558 Species denotes patients Tax:9606
299 698-706 Species denotes patients Tax:9606
300 777-784 Species denotes patient Tax:9606
301 904-912 Species denotes patients Tax:9606
302 946-954 Species denotes patients Tax:9606
303 515-518 Disease denotes HIT MESH:D013921
304 638-646 Disease denotes bleeding MESH:D006470
305 649-673 Disease denotes Thromboembolic phenomena MESH:D013923
306 722-725 Disease denotes HIT MESH:D013921
307 732-741 Disease denotes mortality MESH:D003643
308 790-793 Disease denotes HIT MESH:D013921
309 812-834 Disease denotes venous thromboembolism MESH:D054556
310 844-860 Disease denotes thrombocytopenia MESH:D013921
311 916-919 Disease denotes HIT MESH:D013921
312 925-935 Disease denotes thrombosis MESH:D013927
313 965-975 Disease denotes thrombosis MESH:D013927
316 1129-1132 Disease denotes HIT MESH:D013921
317 1219-1222 Disease denotes HIT MESH:D013921
347 1533-1541 Gene denotes thrombin Gene:2147
348 1725-1733 Gene denotes thrombin Gene:2147
349 1864-1872 Species denotes patients Tax:9606
350 2080-2088 Species denotes patients Tax:9606
351 2532-2540 Species denotes patients Tax:9606
352 1387-1394 Chemical denotes heparin MESH:D006493
353 1406-1413 Chemical denotes heparin MESH:D006493
354 1446-1453 Chemical denotes heparin MESH:D006493
355 1601-1611 Chemical denotes argatroban MESH:C031942
356 1626-1636 Chemical denotes danaparoid MESH:C035838
357 1638-1650 Chemical denotes fondaparinux MESH:D000077425
358 1685-1695 Chemical denotes Argatroban MESH:C031942
359 1883-1893 Chemical denotes argatroban MESH:C031942
360 2031-2041 Chemical denotes argatroban MESH:C031942
361 2220-2228 Chemical denotes warfarin MESH:D014859
362 2507-2517 Chemical denotes argatroban MESH:C031942
363 1372-1375 Disease denotes HIT MESH:D013921
364 1480-1490 Disease denotes thrombotic MESH:D013927
365 1831-1834 Disease denotes HIT MESH:D013921
366 1878-1881 Disease denotes HIT MESH:D013921
367 1936-1941 Disease denotes death MESH:D003643
368 1959-1969 Disease denotes thrombosis MESH:D013927
369 2156-2170 Disease denotes coagulopathies MESH:D001778
370 2172-2191 Disease denotes hepatic dysfunction MESH:D008107
371 2230-2254 Disease denotes consumptive coagulopathy MESH:D004211
372 2275-2283 Disease denotes COVID-19 MESH:C000657245
373 2449-2459 Disease denotes thrombosis MESH:D013927
374 2464-2473 Disease denotes limb loss MESH:D017880
375 2569-2572 Disease denotes HIT MESH:D013921
393 2783-2791 Species denotes patients Tax:9606
394 2805-2813 Species denotes patients Tax:9606
395 2955-2963 Species denotes patients Tax:9606
396 2596-2599 Disease denotes HIT MESH:D013921
397 2720-2723 Disease denotes HIT MESH:D013921
398 2727-2752 Disease denotes Antiphospholipid syndrome MESH:D016736
399 2774-2782 Disease denotes COVID-19 MESH:C000657245
400 2845-2848 Disease denotes HIT MESH:D013921
401 2880-2883 Disease denotes HIT MESH:D013921
402 2921-2937 Disease denotes thrombocytopenia MESH:D013921
403 2940-2954 Disease denotes Critically ill MESH:D016638
404 2989-2992 Disease denotes HIT MESH:D013921
405 3021-3037 Disease denotes thrombocytopenia MESH:D013921
406 3049-3059 Disease denotes septicemia MESH:D018805
407 3061-3085 Disease denotes consumptive coagulopathy MESH:D004211
408 3093-3123 Disease denotes HIT-related pulmonary embolism MESH:D011655
409 3128-3166 Disease denotes catastrophic antiphospholipid syndrome MESH:D016736
415 3537-3545 Species denotes Patients Tax:9606
416 3414-3417 Disease denotes HIT MESH:D013921
417 3499-3502 Disease denotes HIT MESH:D013921
418 3632-3635 Disease denotes HIT MESH:D013921
419 3810-3813 Disease denotes HIT MESH:D013921
436 3958-3961 Gene denotes PF4 Gene:5196
437 4197-4200 Gene denotes PF4 Gene:5196
438 4006-4014 Species denotes patients Tax:9606
439 4091-4099 Species denotes patients Tax:9606
440 4143-4151 Species denotes patients Tax:9606
441 3950-3957 Chemical denotes heparin MESH:D006493
442 4189-4196 Chemical denotes heparin MESH:D006493
443 3997-4005 Disease denotes COVID-19 MESH:C000657245
444 4029-4032 Disease denotes HIT MESH:D013921
445 4157-4165 Disease denotes COVID-19 MESH:C000657245
446 4360-4368 Disease denotes COVID-19 MESH:C000657245
447 4377-4399 Disease denotes venous thromboembolism MESH:D054556
448 4401-4407 Disease denotes sepsis MESH:D018805
449 4409-4431 Disease denotes multiorgan dysfunction MESH:D009102
450 4437-4440 Disease denotes DIC MESH:D004211
451 4468-4471 Disease denotes HIT MESH:D013921
457 4685-4692 Chemical denotes heparin MESH:D006493
458 4747-4754 Chemical denotes heparin MESH:D006493
459 4491-4494 Disease denotes HIT MESH:D013921
460 4578-4588 Disease denotes hemorrhage MESH:D006470
461 4650-4660 Disease denotes thrombosis MESH:D013927

2_test

Id Subject Object Predicate Lexical cue
32720827-28416511-61488851 233-234 28416511 denotes 4
32720827-30482768-61488851 233-234 30482768 denotes 4
32720827-30482768-61488852 290-291 30482768 denotes 6
32720827-30482768-61488853 768-769 30482768 denotes 6
32720827-16113796-61488854 1015-1016 16113796 denotes 7
32720827-30482768-61488855 1133-1134 30482768 denotes 6
32720827-28416511-61488856 1304-1305 28416511 denotes 5
32720827-30482768-61488857 1683-1684 30482768 denotes 6
32720827-28416511-61488858 1733-1734 28416511 denotes 5
32720827-28416511-61488859 2008-2009 28416511 denotes 5
32720827-25590528-61488860 2415-2416 25590528 denotes 8
32720827-25590528-61488861 2573-2574 25590528 denotes 8
32720827-21264902-61488862 2575-2576 21264902 denotes 9
32720827-22195526-61488863 2724-2726 22195526 denotes 10
32720827-32268022-61488864 2792-2794 32268022 denotes 11
32720827-21264902-61488865 2858-2859 21264902 denotes 9
32720827-25590528-61488866 2938-2939 25590528 denotes 8
32720827-25590528-61488867 3167-3168 25590528 denotes 8
32720827-22195526-61488868 3244-3246 22195526 denotes 10
32720827-22195526-61488869 3349-3351 22195526 denotes 10
32720827-18489711-61488870 3352-3354 18489711 denotes 12
32720827-22195526-61488871 3418-3420 22195526 denotes 10
32720827-22195526-61488872 3603-3605 22195526 denotes 10
32720827-18489711-61488873 3606-3608 18489711 denotes 12
32720827-22990018-61488874 3915-3917 22990018 denotes 13
32720827-22990018-61488875 4755-4757 22990018 denotes 13