PMC:7388103 / 5463-6498 JSONTXT

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Characteristics of Patients Who Tested Positive for PF4 Antibody.\nCharacteristics Patient 1a Patient 2 Patient 3 Patient 4 Patient 5\nAge in years 63 53 63 70 46\nSex Male Male Male Female Female\nIndication for anticoagulation DVT Acute coronary syndrome and atrial fibrillation DVT DVT Suspected PE\nConfirmed thrombosis via imaging Yes No Yes Yes No\nDays from initiation of heparin to drop in platelets 11 7 6 8 2\n4T score 6 5 7 7 4\nPF4 antibody (optical density) Positive (1.243) Positive (0.707) Positive (0.767) Positive (0.042) Positive (0.307)\nSerotonin release assay Positive Negative Negative Negative Negative\nPresence of DIC by ISTH criteria No No No Yes Yes\nAbbreviations: DVT, deep vein thrombosis; PE, pulmonary embolism; PF4, platelet factor 4; DIC, disseminated intravascular coagulation; ISTH, International Society on Thrombosis and Haemostasis; HIT, heparin-induced thrombocytopenia.\na Patient 1 had true HIT. 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