PMC:7388103 / 1444-2630
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 696-703 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | Heparin |
T12 | 696-703 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | Heparin |
T13 | 914-921 | https://glytoucan.org/Structures/Glycans/G00021MO | denotes | heparin |
T14 | 914-921 | https://glytoucan.org/Structures/Glycans/G54161DR | denotes | heparin |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T12 | 567-575 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
T13 | 696-703 | Body_part | denotes | Heparin | http://purl.org/sig/ont/fma/fma82839 |
T14 | 914-921 | Body_part | denotes | heparin | http://purl.org/sig/ont/fma/fma82839 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T25 | 447-463 | Disease | denotes | Thrombocytopenia | http://purl.obolibrary.org/obo/MONDO_0002049 |
T26 | 634-642 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T27 | 643-652 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T28 | 658-674 | Disease | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/MONDO_0002049 |
T29 | 696-728 | Disease | denotes | Heparin-induced thrombocytopenia | http://purl.obolibrary.org/obo/MONDO_0018048 |
T30 | 712-728 | Disease | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/MONDO_0002049 |
T31 | 730-733 | Disease | denotes | HIT | http://purl.obolibrary.org/obo/MONDO_0018048 |
T32 | 757-773 | Disease | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/MONDO_0002049 |
T33 | 893-901 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T34 | 937-940 | Disease | denotes | HIT | http://purl.obolibrary.org/obo/MONDO_0018048 |
T35 | 990-993 | Disease | denotes | HIT | http://purl.obolibrary.org/obo/MONDO_0018048 |
T36 | 1021-1029 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T37 | 1030-1039 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T38 | 1112-1115 | Disease | denotes | HIT | http://purl.obolibrary.org/obo/MONDO_0018048 |
T39 | 1151-1154 | Disease | denotes | HIT | http://purl.obolibrary.org/obo/MONDO_0018048 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T20 | 93-94 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T21 | 233-236 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T22 | 406-407 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T23 | 464-467 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T24 | 523-524 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T25 | 552-555 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T26 | 738-739 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T27 | 980-981 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T28 | 997-998 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T10 | 696-703 | Chemical | denotes | Heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
T11 | 914-921 | Chemical | denotes | heparin | http://purl.obolibrary.org/obo/CHEBI_28304 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T17 | 0-12 | Sentence | denotes | Introduction |
T18 | 13-133 | Sentence | denotes | An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, is now a major public health concern worldwide. |
T19 | 134-446 | Sentence | denotes | After the first reported case in the state of Washington, the number of cases in the United States has rapidly increased to over 2 000 000 with more than 100 000 deaths.1 In addition to the typical presentation of respiratory symptoms, hematologic complications have been a significant concern in these patients. |
T20 | 447-816 | Sentence | denotes | Thrombocytopenia has been reported in up to 55% of patients with COVID-19.2 A meta-analysis of 9 studies has shown that platelet counts were significantly lower in those with more severe COVID-19 infection, and thrombocytopenia predicts mortality.2 Heparin-induced thrombocytopenia (HIT) is a differential for thrombocytopenia, especially in the intensive care setting. |
T21 | 817-1040 | Sentence | denotes | In one review, the authors suggested that clinicians routinely evaluate all COVID-19 patients on heparin for indices of HIT by performing the 4T score.3 We report a case of HIT in a patient with critical COVID-19 infection. |
T22 | 1041-1186 | Sentence | denotes | Also, we briefly describe 4 other cases that were initially managed as HIT, until proven later not to be true HIT, based on the functional assay. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T14 | 447-463 | Phenotype | denotes | Thrombocytopenia | http://purl.obolibrary.org/obo/HP_0001873 |
T15 | 658-674 | Phenotype | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/HP_0001873 |
T16 | 696-728 | Phenotype | denotes | Heparin-induced thrombocytopenia | http://purl.obolibrary.org/obo/HP_0011874 |
T17 | 730-733 | Phenotype | denotes | HIT | http://purl.obolibrary.org/obo/HP_0011874 |
T18 | 757-773 | Phenotype | denotes | thrombocytopenia | http://purl.obolibrary.org/obo/HP_0001873 |
T19 | 937-940 | Phenotype | denotes | HIT | http://purl.obolibrary.org/obo/HP_0011874 |
T20 | 990-993 | Phenotype | denotes | HIT | http://purl.obolibrary.org/obo/HP_0011874 |
T21 | 1112-1115 | Phenotype | denotes | HIT | http://purl.obolibrary.org/obo/HP_0011874 |
T22 | 1151-1154 | Phenotype | denotes | HIT | http://purl.obolibrary.org/obo/HP_0011874 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
61 | 28-45 | Species | denotes | novel coronavirus | Tax:2697049 |
62 | 47-56 | Species | denotes | 2019-nCoV | Tax:2697049 |
63 | 437-445 | Species | denotes | patients | Tax:9606 |
64 | 296-302 | Disease | denotes | deaths | MESH:D003643 |
65 | 348-368 | Disease | denotes | respiratory symptoms | MESH:D012818 |
87 | 498-506 | Species | denotes | patients | Tax:9606 |
88 | 902-910 | Species | denotes | patients | Tax:9606 |
89 | 999-1006 | Species | denotes | patient | Tax:9606 |
90 | 696-703 | Chemical | denotes | Heparin | MESH:D006493 |
91 | 914-921 | Chemical | denotes | heparin | MESH:D006493 |
92 | 447-463 | Disease | denotes | Thrombocytopenia | MESH:D013921 |
93 | 512-520 | Disease | denotes | COVID-19 | MESH:C000657245 |
94 | 634-642 | Disease | denotes | COVID-19 | MESH:C000657245 |
95 | 643-652 | Disease | denotes | infection | MESH:D007239 |
96 | 658-674 | Disease | denotes | thrombocytopenia | MESH:D013921 |
97 | 684-693 | Disease | denotes | mortality | MESH:D003643 |
98 | 712-728 | Disease | denotes | thrombocytopenia | MESH:D013921 |
99 | 730-733 | Disease | denotes | HIT | MESH:D013921 |
100 | 757-773 | Disease | denotes | thrombocytopenia | MESH:D013921 |
101 | 893-901 | Disease | denotes | COVID-19 | MESH:C000657245 |
102 | 937-940 | Disease | denotes | HIT | MESH:D013921 |
103 | 990-993 | Disease | denotes | HIT | MESH:D013921 |
104 | 1021-1029 | Disease | denotes | COVID-19 | MESH:C000657245 |
105 | 1030-1039 | Disease | denotes | infection | MESH:D007239 |
106 | 1112-1115 | Disease | denotes | HIT | MESH:D013921 |
107 | 1151-1154 | Disease | denotes | HIT | MESH:D013921 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32720827-32178975-61488848 | 521-522 | 32178975 | denotes | 2 |
32720827-32178975-61488849 | 694-695 | 32178975 | denotes | 2 |
32720827-32282949-61488850 | 968-969 | 32282949 | denotes | 3 |