PMC:7386875 / 47337-48016 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7386875","sourcedb":"PMC","sourceid":"7386875","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7386875","text":"The strikingly increased prevalence of thrombotic complications has led to many hospitals instituting the routine administration of strict VTE prophylaxis with either low molecular weight heparin or unfractionated heparin and also resulting in several groups using intermediate or full-dose anticoagulation to prevent these thromboembolic phenomena.137,138 Preliminary reports have suggested that low molecular weight heparin treatment reduces mortality in COVID-19 patients with an elevated D-dimer or elevated sepsis-induced coagulopathy score.139 The heparins are widely used anticoagulants which inhibit coagulation by the antithrombin mediated inhibition of FXa or thrombin.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T468","span":{"begin":188,"end":195},"obj":"Body_part"},{"id":"T469","span":{"begin":214,"end":221},"obj":"Body_part"},{"id":"T470","span":{"begin":418,"end":425},"obj":"Body_part"},{"id":"T471","span":{"begin":554,"end":562},"obj":"Body_part"}],"attributes":[{"id":"A468","pred":"fma_id","subj":"T468","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A469","pred":"fma_id","subj":"T469","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A470","pred":"fma_id","subj":"T470","obj":"http://purl.org/sig/ont/fma/fma82839"},{"id":"A471","pred":"fma_id","subj":"T471","obj":"http://purl.org/sig/ont/fma/fma82839"},{"subj":"T468","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T469","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T470","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T471","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T356","span":{"begin":139,"end":142},"obj":"Disease"},{"id":"T357","span":{"begin":457,"end":465},"obj":"Disease"},{"id":"T358","span":{"begin":527,"end":539},"obj":"Disease"}],"attributes":[{"id":"A356","pred":"mondo_id","subj":"T356","obj":"http://purl.obolibrary.org/obo/MONDO_0005399"},{"id":"A357","pred":"mondo_id","subj":"T357","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A358","pred":"mondo_id","subj":"T358","obj":"http://purl.obolibrary.org/obo/MONDO_0001531"},{"subj":"T356","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T357","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T358","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T507","span":{"begin":64,"end":67},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"attributes":[{"subj":"T507","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T281","span":{"begin":188,"end":195},"obj":"Chemical"},{"id":"T282","span":{"begin":214,"end":221},"obj":"Chemical"},{"id":"T283","span":{"begin":418,"end":425},"obj":"Chemical"},{"id":"T284","span":{"begin":554,"end":562},"obj":"Chemical"},{"id":"T285","span":{"begin":579,"end":593},"obj":"Chemical"}],"attributes":[{"id":"A281","pred":"chebi_id","subj":"T281","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A282","pred":"chebi_id","subj":"T282","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A283","pred":"chebi_id","subj":"T283","obj":"http://purl.obolibrary.org/obo/CHEBI_28304"},{"id":"A284","pred":"chebi_id","subj":"T284","obj":"http://purl.obolibrary.org/obo/CHEBI_24505"},{"id":"A285","pred":"chebi_id","subj":"T285","obj":"http://purl.obolibrary.org/obo/CHEBI_50249"},{"subj":"T281","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T282","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T283","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T284","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T285","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T66","span":{"begin":324,"end":338},"obj":"Phenotype"},{"id":"T67","span":{"begin":483,"end":499},"obj":"Phenotype"},{"id":"T68","span":{"begin":512,"end":518},"obj":"Phenotype"},{"id":"T69","span":{"begin":527,"end":539},"obj":"Phenotype"}],"attributes":[{"id":"A66","pred":"hp_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/HP_0001907"},{"id":"A67","pred":"hp_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/HP_0033106"},{"id":"A68","pred":"hp_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/HP_0100806"},{"id":"A69","pred":"hp_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/HP_0003256"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T151","span":{"begin":600,"end":619},"obj":"http://purl.obolibrary.org/obo/GO_0050819"},{"id":"T152","span":{"begin":608,"end":619},"obj":"http://purl.obolibrary.org/obo/GO_0050817"}],"attributes":[{"subj":"T151","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T152","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T165","span":{"begin":0,"end":679},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T165","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32586214-32311448-21597810","span":{"begin":349,"end":352},"obj":"32311448"},{"id":"32586214-32339221-21597811","span":{"begin":353,"end":356},"obj":"32339221"},{"id":"32586214-32220112-21597812","span":{"begin":546,"end":549},"obj":"32220112"}],"attributes":[{"subj":"32586214-32311448-21597810","pred":"source","obj":"2_test"},{"subj":"32586214-32339221-21597811","pred":"source","obj":"2_test"},{"subj":"32586214-32220112-21597812","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1605","span":{"begin":627,"end":639},"obj":"Gene"},{"id":"1606","span":{"begin":663,"end":666},"obj":"Gene"},{"id":"1607","span":{"begin":670,"end":678},"obj":"Gene"},{"id":"1612","span":{"begin":466,"end":474},"obj":"Species"},{"id":"1617","span":{"begin":167,"end":195},"obj":"Chemical"},{"id":"1618","span":{"begin":214,"end":221},"obj":"Chemical"},{"id":"1619","span":{"begin":397,"end":425},"obj":"Chemical"},{"id":"1620","span":{"begin":554,"end":562},"obj":"Chemical"},{"id":"1635","span":{"begin":39,"end":63},"obj":"Disease"},{"id":"1636","span":{"begin":139,"end":142},"obj":"Disease"},{"id":"1637","span":{"begin":324,"end":348},"obj":"Disease"},{"id":"1638","span":{"begin":444,"end":453},"obj":"Disease"},{"id":"1639","span":{"begin":457,"end":465},"obj":"Disease"},{"id":"1640","span":{"begin":512,"end":518},"obj":"Disease"},{"id":"1641","span":{"begin":527,"end":539},"obj":"Disease"}],"attributes":[{"id":"A1605","pred":"tao:has_database_id","subj":"1605","obj":"Gene:462"},{"id":"A1606","pred":"tao:has_database_id","subj":"1606","obj":"Gene:2159"},{"id":"A1607","pred":"tao:has_database_id","subj":"1607","obj":"Gene:2147"},{"id":"A1612","pred":"tao:has_database_id","subj":"1612","obj":"Tax:9606"},{"id":"A1617","pred":"tao:has_database_id","subj":"1617","obj":"MESH:D006495"},{"id":"A1618","pred":"tao:has_database_id","subj":"1618","obj":"MESH:D006493"},{"id":"A1619","pred":"tao:has_database_id","subj":"1619","obj":"MESH:D006495"},{"id":"A1620","pred":"tao:has_database_id","subj":"1620","obj":"MESH:D006493"},{"id":"A1635","pred":"tao:has_database_id","subj":"1635","obj":"MESH:D013927"},{"id":"A1636","pred":"tao:has_database_id","subj":"1636","obj":"MESH:D054556"},{"id":"A1637","pred":"tao:has_database_id","subj":"1637","obj":"MESH:D013923"},{"id":"A1638","pred":"tao:has_database_id","subj":"1638","obj":"MESH:D003643"},{"id":"A1639","pred":"tao:has_database_id","subj":"1639","obj":"MESH:C000657245"},{"id":"A1640","pred":"tao:has_database_id","subj":"1640","obj":"MESH:D018805"},{"id":"A1641","pred":"tao:has_database_id","subj":"1641","obj":"MESH:D001778"},{"subj":"1605","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1606","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1607","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1612","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1617","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1618","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1619","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1620","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1635","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1636","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1637","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1638","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1639","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1640","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1641","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#eca993","default":true},{"id":"LitCovid-PD-MONDO","color":"#9397ec"},{"id":"LitCovid-PD-CLO","color":"#b1ec93"},{"id":"LitCovid-PD-CHEBI","color":"#ec93cb"},{"id":"LitCovid-PD-HP","color":"#93e5ec"},{"id":"LitCovid-PD-GO-BP","color":"#ecd993"},{"id":"LitCovid-sentences","color":"#bf93ec"},{"id":"2_test","color":"#93eca5"},{"id":"LitCovid-PubTator","color":"#ec939a"}]}]}}