PMC:7386875 / 433-985 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":347,"end":364},"obj":"Body_part"},{"id":"T2","span":{"begin":359,"end":364},"obj":"Body_part"},{"id":"T3","span":{"begin":436,"end":452},"obj":"Body_part"},{"id":"T4","span":{"begin":448,"end":452},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T8","span":{"begin":12,"end":22},"obj":"Disease"},{"id":"T9","span":{"begin":24,"end":45},"obj":"Disease"},{"id":"T10","span":{"begin":59,"end":65},"obj":"Disease"},{"id":"T12","span":{"begin":127,"end":135},"obj":"Disease"},{"id":"T13","span":{"begin":160,"end":178},"obj":"Disease"},{"id":"T14","span":{"begin":291,"end":299},"obj":"Disease"},{"id":"T15","span":{"begin":326,"end":334},"obj":"Disease"},{"id":"T16","span":{"begin":488,"end":496},"obj":"Disease"},{"id":"T17","span":{"begin":524,"end":536},"obj":"Disease"}],"attributes":[{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0000831"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005399"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005098"},{"id":"A11","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0043726"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T5","span":{"begin":347,"end":364},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T6","span":{"begin":436,"end":452},"obj":"http://purl.obolibrary.org/obo/CL_0000115"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":376,"end":387},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":31,"end":53},"obj":"Phenotype"},{"id":"T2","span":{"begin":59,"end":65},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001907"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0001297"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":524,"end":536},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-sentences","denotations":[{"id":"T5","span":{"begin":67,"end":203},"obj":"Sentence"},{"id":"T6","span":{"begin":204,"end":461},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}

{"project":"LitCovid-PubTator","denotations":[{"id":"48","span":{"begin":369,"end":374},"obj":"Gene"},{"id":"49","span":{"begin":376,"end":407},"obj":"Gene"},{"id":"53","span":{"begin":326,"end":336},"obj":"Species"},{"id":"54","span":{"begin":474,"end":482},"obj":"Species"},{"id":"63","span":{"begin":12,"end":22},"obj":"Disease"},{"id":"64","span":{"begin":24,"end":53},"obj":"Disease"},{"id":"65","span":{"begin":59,"end":65},"obj":"Disease"},{"id":"66","span":{"begin":80,"end":104},"obj":"Disease"},{"id":"67","span":{"begin":127,"end":135},"obj":"Disease"},{"id":"68","span":{"begin":160,"end":178},"obj":"Disease"},{"id":"69","span":{"begin":193,"end":202},"obj":"Disease"},{"id":"70","span":{"begin":255,"end":265},"obj":"Disease"},{"id":"71","span":{"begin":291,"end":299},"obj":"Disease"},{"id":"72","span":{"begin":488,"end":496},"obj":"Disease"},{"id":"73","span":{"begin":524,"end":536},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Gene:59272"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Gene:59272"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"Tax:2697049"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:9606"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"MESH:D013927"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"MESH:D054556"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"MESH:D020521"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"MESH:D013927"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"MESH:C000657245"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"MESH:D009102"},{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"MESH:D003643"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"MESH:D013927"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"MESH:C000657245"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:C000657245"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"crovascular thrombosis, venous thromboembolic disease, and stroke. Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. However, in patients with COVID-19 the subsequent endothelial inflammation, complement act"}