PMC:7386875 / 30802-31727
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T286 | 27-31 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T287 | 43-52 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
| T288 | 68-72 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T289 | 73-87 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
| T290 | 89-91 | Body_part | denotes | Ig | http://purl.org/sig/ont/fma/fma62871 |
| T291 | 254-266 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T292 | 267-270 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T293 | 726-735 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
| T294 | 853-858 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T51 | 853-858 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T250 | 175-183 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T251 | 323-333 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T252 | 456-464 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T253 | 490-495 | Disease | denotes | lupus | http://purl.obolibrary.org/obo/MONDO_0004670 |
| T254 | 577-585 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T255 | 602-610 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T256 | 622-632 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T257 | 777-785 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T258 | 838-848 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T259 | 859-865 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T299 | 25-31 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T-cell |
| T300 | 66-72 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T301 | 376-377 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T302 | 413-414 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T303 | 477-478 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T304 | 510-512 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T305 | 592-593 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T306 | 853-858 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T146 | 254-266 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T147 | 496-509 | Chemical | denotes | anticoagulant | http://purl.obolibrary.org/obo/CHEBI_50249 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T49 | 209-236 | Phenotype | denotes | antiphospholipid antibodies | http://purl.obolibrary.org/obo/HP_0003613 |
| T50 | 490-509 | Phenotype | denotes | lupus anticoagulant | http://purl.obolibrary.org/obo/HP_0025343 |
| T51 | 546-573 | Phenotype | denotes | antiphospholipid antibodies | http://purl.obolibrary.org/obo/HP_0003613 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T83 | 749-773 | http://purl.obolibrary.org/obo/GO_0002250 | denotes | adaptive immune response |
| T84 | 758-773 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T109 | 0-695 | Sentence | denotes | In addition to mediating T-cell functions, platelets can increase B-cell immunoglobulin (Ig)G1, IgG2, and IgG3 production.90 This is potentially significant in the setting of COVID-19 since the development of antiphospholipid antibodies, such as anti-β2 glycoprotein IgG antibodies, have been described in association with thrombosis in patients with COVID-19.91 In addition, a cohort study from France describes a large percentage of patients with severe COVID-19 demonstrate a detectable lupus anticoagulant.27 However, whether the presence of antiphospholipid antibodies in COVID-19 plays a role in COVID-19-associated thrombosis or represents merely an association remains to be established. |
| T110 | 696-925 | Sentence | denotes | Nevertheless, delineating how platelets modulate the adaptive immune response to SARS-CoV-2 and the role adaptive immunity plays in mediating thrombosis and organ injury will be crucial in uncovering novel therapeutic strategies. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32586214-17656005-21597751 | 122-124 | 17656005 | denotes | 90 |
| 32586214-32268022-21597752 | 360-362 | 32268022 | denotes | 91 |
| 32586214-32367170-21597753 | 510-512 | 32367170 | denotes | 27 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1064 | 106-110 | Gene | denotes | IgG3 | Gene:3502 |
| 1065 | 251-253 | Gene | denotes | β2 | Gene:170589 |
| 1066 | 337-345 | Species | denotes | patients | Tax:9606 |
| 1067 | 435-443 | Species | denotes | patients | Tax:9606 |
| 1068 | 777-787 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1069 | 175-183 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1070 | 323-333 | Disease | denotes | thrombosis | MESH:D013927 |
| 1071 | 351-359 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1072 | 456-464 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1073 | 577-585 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1074 | 602-610 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1075 | 622-632 | Disease | denotes | thrombosis | MESH:D013927 |
| 1076 | 838-848 | Disease | denotes | thrombosis | MESH:D013927 |
| 1077 | 853-865 | Disease | denotes | organ injury | MESH:D009102 |