PMC:7386875 / 18198-22929 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7386875","sourcedb":"PMC","sourceid":"7386875","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7386875","text":"COVID-19 and the Endothelium—Hijacking the Guardian of Vascular Integrity\nThe primary site of human infection with SARS-CoV-2 is the lung, where S1 attaches with high affinity to ACE-2 expressed on lung alveolar type II epithelial cells (Figure 1).1,2,5 The replication and release of virus from infected cells results in pyroptosis, a highly inflammatory form of cell death that is a common feature among many cytopathic viruses. PRR (Pattern recognition receptors), such as TLR (Toll-like receptors), subsequently detect the release of pathogen-associated molecular patterns, and intracellular danger-associated molecular patterns, such as ATP and DNA, which evokes an intense inflammatory reaction and triggers the release of proinflammatory chemokines and cytokines from neighboring cells (Figure 1).46 Strikingly, SARS-CoV-2 has been found to contain multiple single-stranded RNA fragments that can be recognized by TLR-7 and TLR-8, similar in numbers to MERS-CoV but more than SARS-CoV.47 The recognition of SARS-CoV-2 by these receptors may contribute to innate immune hyperactivation and the cytokine storm often seen in severe COVID-19.\nIn the setting of SARS-CoV-2 infection, the vascular endothelium appears to be targeted directly by the virus as well as the milieu of proinflammatory cytokines elicited by the immune response.48 ACE-2 is also expressed widely in extrapulmonary sites including blood vessels, heart, kidney, and intestine.49,50 Accordingly, viral RNA has been detected in urine and stool samples from patients with COVID-19.51,52 In this regard, it is currently hypothesized that viral entry via endothelial-expressed ACE-2 represents a mechanism by which the virus can enter and infect other tissues. Recent experimental data have highlighted the ability of COVID-19 to infect human endothelial cells. Indeed, human blood vessel organoids, which closely resemble human capillaries, contain viral RNA after exposure to COVID-19 in vitro.53 Strikingly, the application of human recombinant soluble ACE-2 markedly inhibited viral infection in human capillary organoids, pointing to a direct role for endothelial ACE-2 in viral uptake in blood vessels. Intriguingly, the uptake of SARS-CoV-2 into cells is associated with the downregulation of ACE-2 expression.54,55 This appears to play an important role in promoting a proinflammatory and prothrombotic milieu since ACE-2 plays a pivotal role in regulating the RAS (renin-angiotensin system), by degrading angiotensin II to angiotensin 1–7. While angiotensin II induces vasoconstriction and promotes a proinflammatory/prothrombotic phenotype, angiotensin 1–7 opposes these effects via binding to the MAS receptor, which is widely expressed including on endothelial cells and platelets.55\nInterestingly, patients with SARS-CoV-2 have been demonstrated to have increased levels of IL (interleukin)-6, IL-1β, IFN (interferon)-γ, MCP-1 (monocyte chemoattractant protein 1), MIP (macrophage inflammatory protein), and IP10 (CXCL10).11 These proinflammatory cytokines can disrupt endothelial function and integrity leading to the release of VWF, upregulation of adhesion molecules, such as ICAM (intercellular adhesion molecule)-1, integrin αvβ3, P- and E-selectin, and the production of endothelial cytokines and chemokines.56,57 Thus, the endothelium adopts a proinflammatory and procoagulant phenotype that supports the recruitment of platelets and leukocytes.58,59 Furthermore, these changes are associated with the downregulation of the natural anticoagulants and corresponding upregulation of endothelial tissue factor (TF, CD142).57 Moreover, a common finding in patients with COVID-19 is profound hypoxia. Although not formally tested in the context of SARS-CoV-2 infection, hypoxia is also likely to induce a prothrombotic endothelial phenotype since vascular hypoxia induces the activation of HIFs (hypoxia-inducible transcription factors) that have been demonstrated to upregulate endothelial TF expression while downregulating the natural anticoagulants, Protein S and TFPI (tissue factor pathway inhibitor), thus imparting a procoagulant endothelial phenotype.60\nA recent case series of autopsy sections from patients with COVID-19 aligns with these experimental findings described above and highlight the ability of COVID-19 to infect endothelial cells and cause endothelial injury. Sections of lung, kidney, and intestine from patients with COVID-19 demonstrate evidence of viral inclusion within endothelial cells, in addition to histological evidence of endothelial inflammation and cell death.48 These data point to a direct role of COVID-19 in promoting systemic microvascular dysfunction which potentially promotes a prothrombotic state.53","divisions":[{"label":"title","span":{"begin":0,"end":73}},{"label":"p","span":{"begin":74,"end":1145}},{"label":"p","span":{"begin":1146,"end":2765}},{"label":"p","span":{"begin":2766,"end":4147}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T111","span":{"begin":17,"end":28},"obj":"Body_part"},{"id":"T112","span":{"begin":133,"end":137},"obj":"Body_part"},{"id":"T113","span":{"begin":198,"end":202},"obj":"Body_part"},{"id":"T114","span":{"begin":203,"end":211},"obj":"Body_part"},{"id":"T115","span":{"begin":220,"end":236},"obj":"Body_part"},{"id":"T116","span":{"begin":231,"end":236},"obj":"Body_part"},{"id":"T117","span":{"begin":305,"end":310},"obj":"Body_part"},{"id":"T118","span":{"begin":364,"end":368},"obj":"Body_part"},{"id":"T119","span":{"begin":650,"end":653},"obj":"Body_part"},{"id":"T120","span":{"begin":745,"end":755},"obj":"Body_part"},{"id":"T121","span":{"begin":760,"end":769},"obj":"Body_part"},{"id":"T122","span":{"begin":787,"end":792},"obj":"Body_part"},{"id":"T123","span":{"begin":881,"end":884},"obj":"Body_part"},{"id":"T124","span":{"begin":1100,"end":1108},"obj":"Body_part"},{"id":"T125","span":{"begin":1199,"end":1210},"obj":"Body_part"},{"id":"T126","span":{"begin":1297,"end":1306},"obj":"Body_part"},{"id":"T127","span":{"begin":1407,"end":1420},"obj":"Body_part"},{"id":"T128","span":{"begin":1407,"end":1412},"obj":"Body_part"},{"id":"T129","span":{"begin":1422,"end":1427},"obj":"Body_part"},{"id":"T130","span":{"begin":1429,"end":1435},"obj":"Body_part"},{"id":"T131","span":{"begin":1441,"end":1450},"obj":"Body_part"},{"id":"T132","span":{"begin":1476,"end":1479},"obj":"Body_part"},{"id":"T133","span":{"begin":1501,"end":1506},"obj":"Body_part"},{"id":"T134","span":{"begin":1511,"end":1516},"obj":"Body_part"},{"id":"T135","span":{"begin":1722,"end":1729},"obj":"Body_part"},{"id":"T136","span":{"begin":1813,"end":1830},"obj":"Body_part"},{"id":"T137","span":{"begin":1825,"end":1830},"obj":"Body_part"},{"id":"T138","span":{"begin":1846,"end":1858},"obj":"Body_part"},{"id":"T139","span":{"begin":1899,"end":1910},"obj":"Body_part"},{"id":"T140","span":{"begin":1926,"end":1929},"obj":"Body_part"},{"id":"T141","span":{"begin":2076,"end":2085},"obj":"Body_part"},{"id":"T142","span":{"begin":2164,"end":2177},"obj":"Body_part"},{"id":"T143","span":{"begin":2164,"end":2169},"obj":"Body_part"},{"id":"T144","span":{"begin":2223,"end":2228},"obj":"Body_part"},{"id":"T145","span":{"begin":2731,"end":2748},"obj":"Body_part"},{"id":"T146","span":{"begin":2743,"end":2748},"obj":"Body_part"},{"id":"T147","span":{"begin":2753,"end":2762},"obj":"Body_part"},{"id":"T148","span":{"begin":2860,"end":2875},"obj":"Body_part"},{"id":"T149","span":{"begin":2861,"end":2872},"obj":"Body_part"},{"id":"T150","span":{"begin":2877,"end":2881},"obj":"Body_part"},{"id":"T151","span":{"begin":2911,"end":2919},"obj":"Body_part"},{"id":"T152","span":{"begin":2936,"end":2943},"obj":"Body_part"},{"id":"T153","span":{"begin":2953,"end":2963},"obj":"Body_part"},{"id":"T154","span":{"begin":2977,"end":2984},"obj":"Body_part"},{"id":"T155","span":{"begin":3030,"end":3039},"obj":"Body_part"},{"id":"T156","span":{"begin":3162,"end":3166},"obj":"Body_part"},{"id":"T157","span":{"begin":3204,"end":3212},"obj":"Body_part"},{"id":"T158","span":{"begin":3226,"end":3236},"obj":"Body_part"},{"id":"T159","span":{"begin":3272,"end":3281},"obj":"Body_part"},{"id":"T160","span":{"begin":3286,"end":3296},"obj":"Body_part"},{"id":"T161","span":{"begin":3313,"end":3324},"obj":"Body_part"},{"id":"T162","span":{"begin":3410,"end":3419},"obj":"Body_part"},{"id":"T163","span":{"begin":3424,"end":3434},"obj":"Body_part"},{"id":"T164","span":{"begin":3583,"end":3589},"obj":"Body_part"},{"id":"T165","span":{"begin":4039,"end":4046},"obj":"Body_part"},{"id":"T166","span":{"begin":4059,"end":4065},"obj":"Body_part"},{"id":"T167","span":{"begin":4321,"end":4338},"obj":"Body_part"},{"id":"T168","span":{"begin":4333,"end":4338},"obj":"Body_part"},{"id":"T169","span":{"begin":4381,"end":4385},"obj":"Body_part"},{"id":"T170","span":{"begin":4387,"end":4393},"obj":"Body_part"},{"id":"T171","span":{"begin":4399,"end":4408},"obj":"Body_part"},{"id":"T172","span":{"begin":4484,"end":4501},"obj":"Body_part"},{"id":"T173","span":{"begin":4496,"end":4501},"obj":"Body_part"},{"id":"T174","span":{"begin":4572,"end":4576},"obj":"Body_part"}],"attributes":[{"id":"A111","pred":"fma_id","subj":"T111","obj":"http://purl.org/sig/ont/fma/fma63916"},{"id":"A112","pred":"fma_id","subj":"T112","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A113","pred":"fma_id","subj":"T113","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A114","pred":"fma_id","subj":"T114","obj":"http://purl.org/sig/ont/fma/fma264783"},{"id":"A115","pred":"fma_id","subj":"T115","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A116","pred":"fma_id","subj":"T116","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A117","pred":"fma_id","subj":"T117","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A118","pred":"fma_id","subj":"T118","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A119","pred":"fma_id","subj":"T119","obj":"http://purl.org/sig/ont/fma/fma74412"},{"id":"A120","pred":"fma_id","subj":"T120","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A121","pred":"fma_id","subj":"T121","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A122","pred":"fma_id","subj":"T122","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A123","pred":"fma_id","subj":"T123","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A124","pred":"fma_id","subj":"T124","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A125","pred":"fma_id","subj":"T125","obj":"http://purl.org/sig/ont/fma/fma63916"},{"id":"A126","pred":"fma_id","subj":"T126","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A127","pred":"fma_id","subj":"T127","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A128","pred":"fma_id","subj":"T128","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A129","pred":"fma_id","subj":"T129","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A130","pred":"fma_id","subj":"T130","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A131","pred":"fma_id","subj":"T131","obj":"http://purl.org/sig/ont/fma/fma7199"},{"id":"A132","pred":"fma_id","subj":"T132","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A133","pred":"fma_id","subj":"T133","obj":"http://purl.org/sig/ont/fma/fma12274"},{"id":"A134","pred":"fma_id","subj":"T134","obj":"http://purl.org/sig/ont/fma/fma64183"},{"id":"A135","pred":"fma_id","subj":"T135","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A136","pred":"fma_id","subj":"T136","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A137","pred":"fma_id","subj":"T137","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A138","pred":"fma_id","subj":"T138","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A139","pred":"fma_id","subj":"T139","obj":"http://purl.org/sig/ont/fma/fma63194"},{"id":"A140","pred":"fma_id","subj":"T140","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A141","pred":"fma_id","subj":"T141","obj":"http://purl.org/sig/ont/fma/fma63194"},{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A145","pred":"fma_id","subj":"T145","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A146","pred":"fma_id","subj":"T146","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A147","pred":"fma_id","subj":"T147","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A148","pred":"fma_id","subj":"T148","obj":"http://purl.org/sig/ont/fma/fma264829"},{"id":"A149","pred":"fma_id","subj":"T149","obj":"http://purl.org/sig/ont/fma/fma86578"},{"id":"A150","pred":"fma_id","subj":"T150","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A151","pred":"fma_id","subj":"T151","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A152","pred":"fma_id","subj":"T152","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A153","pred":"fma_id","subj":"T153","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A154","pred":"fma_id","subj":"T154","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A155","pred":"fma_id","subj":"T155","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A156","pred":"fma_id","subj":"T156","obj":"http://purl.org/sig/ont/fma/fma67857"},{"id":"A157","pred":"fma_id","subj":"T157","obj":"http://purl.org/sig/ont/fma/fma67222"},{"id":"A158","pred":"fma_id","subj":"T158","obj":"http://purl.org/sig/ont/fma/fma62932"},{"id":"A159","pred":"fma_id","subj":"T159","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A160","pred":"fma_id","subj":"T160","obj":"http://purl.org/sig/ont/fma/fma241981"},{"id":"A161","pred":"fma_id","subj":"T161","obj":"http://purl.org/sig/ont/fma/fma63916"},{"id":"A162","pred":"fma_id","subj":"T162","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A163","pred":"fma_id","subj":"T163","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A164","pred":"fma_id","subj":"T164","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A165","pred":"fma_id","subj":"T165","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A166","pred":"fma_id","subj":"T166","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A167","pred":"fma_id","subj":"T167","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A168","pred":"fma_id","subj":"T168","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A169","pred":"fma_id","subj":"T169","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma7199"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma66772"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A174","pred":"fma_id","subj":"T174","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T116","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T117","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T118","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T119","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T120","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T121","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T122","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T123","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T124","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T125","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T126","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T127","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T128","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T129","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T130","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T131","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T132","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T133","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T134","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T135","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T136","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T137","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T138","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T139","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T140","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T141","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T142","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T143","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T144","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T145","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T146","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T147","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T148","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T149","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T150","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T151","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T152","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T153","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T154","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T155","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T156","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T157","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T158","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T159","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T160","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T161","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T162","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T163","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T164","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T165","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T166","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T167","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T168","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T169","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T20","span":{"begin":17,"end":28},"obj":"Body_part"},{"id":"T21","span":{"begin":133,"end":137},"obj":"Body_part"},{"id":"T22","span":{"begin":198,"end":202},"obj":"Body_part"},{"id":"T23","span":{"begin":1199,"end":1210},"obj":"Body_part"},{"id":"T24","span":{"begin":1407,"end":1420},"obj":"Body_part"},{"id":"T25","span":{"begin":1407,"end":1412},"obj":"Body_part"},{"id":"T26","span":{"begin":1413,"end":1420},"obj":"Body_part"},{"id":"T27","span":{"begin":1422,"end":1427},"obj":"Body_part"},{"id":"T28","span":{"begin":1429,"end":1435},"obj":"Body_part"},{"id":"T29","span":{"begin":1441,"end":1450},"obj":"Body_part"},{"id":"T30","span":{"begin":1501,"end":1506},"obj":"Body_part"},{"id":"T31","span":{"begin":1511,"end":1516},"obj":"Body_part"},{"id":"T32","span":{"begin":1846,"end":1858},"obj":"Body_part"},{"id":"T33","span":{"begin":1846,"end":1851},"obj":"Body_part"},{"id":"T34","span":{"begin":1852,"end":1858},"obj":"Body_part"},{"id":"T35","span":{"begin":2076,"end":2085},"obj":"Body_part"},{"id":"T36","span":{"begin":2164,"end":2177},"obj":"Body_part"},{"id":"T37","span":{"begin":2164,"end":2169},"obj":"Body_part"},{"id":"T38","span":{"begin":2170,"end":2177},"obj":"Body_part"},{"id":"T39","span":{"begin":2444,"end":2468},"obj":"Body_part"},{"id":"T40","span":{"begin":3313,"end":3324},"obj":"Body_part"},{"id":"T41","span":{"begin":3583,"end":3589},"obj":"Body_part"},{"id":"T42","span":{"begin":4059,"end":4065},"obj":"Body_part"},{"id":"T43","span":{"begin":4381,"end":4385},"obj":"Body_part"},{"id":"T44","span":{"begin":4387,"end":4393},"obj":"Body_part"},{"id":"T45","span":{"begin":4399,"end":4408},"obj":"Body_part"}],"attributes":[{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0001088"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0001988"},{"id":"A32","pred":"uberon_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A33","pred":"uberon_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A34","pred":"uberon_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"A35","pred":"uberon_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/UBERON_0001982"},{"id":"A36","pred":"uberon_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A38","pred":"uberon_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"A39","pred":"uberon_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"},{"id":"A40","pred":"uberon_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"A41","pred":"uberon_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A42","pred":"uberon_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A43","pred":"uberon_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A44","pred":"uberon_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A45","pred":"uberon_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T181","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"T182","span":{"begin":100,"end":109},"obj":"Disease"},{"id":"T183","span":{"begin":115,"end":123},"obj":"Disease"},{"id":"T184","span":{"begin":819,"end":827},"obj":"Disease"},{"id":"T185","span":{"begin":983,"end":991},"obj":"Disease"},{"id":"T186","span":{"begin":1014,"end":1022},"obj":"Disease"},{"id":"T187","span":{"begin":1136,"end":1144},"obj":"Disease"},{"id":"T188","span":{"begin":1164,"end":1172},"obj":"Disease"},{"id":"T189","span":{"begin":1175,"end":1184},"obj":"Disease"},{"id":"T190","span":{"begin":1788,"end":1796},"obj":"Disease"},{"id":"T191","span":{"begin":1948,"end":1956},"obj":"Disease"},{"id":"T192","span":{"begin":2051,"end":2066},"obj":"Disease"},{"id":"T193","span":{"begin":2057,"end":2066},"obj":"Disease"},{"id":"T194","span":{"begin":2207,"end":2215},"obj":"Disease"},{"id":"T195","span":{"begin":2795,"end":2803},"obj":"Disease"},{"id":"T196","span":{"begin":3656,"end":3664},"obj":"Disease"},{"id":"T197","span":{"begin":3733,"end":3741},"obj":"Disease"},{"id":"T198","span":{"begin":3744,"end":3753},"obj":"Disease"},{"id":"T199","span":{"begin":4208,"end":4216},"obj":"Disease"},{"id":"T200","span":{"begin":4302,"end":4310},"obj":"Disease"},{"id":"T201","span":{"begin":4361,"end":4367},"obj":"Disease"},{"id":"T202","span":{"begin":4428,"end":4436},"obj":"Disease"},{"id":"T203","span":{"begin":4555,"end":4567},"obj":"Disease"},{"id":"T204","span":{"begin":4623,"end":4631},"obj":"Disease"}],"attributes":[{"id":"A181","pred":"mondo_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A182","pred":"mondo_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A183","pred":"mondo_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A184","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A185","pred":"mondo_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A186","pred":"mondo_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A187","pred":"mondo_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A188","pred":"mondo_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A189","pred":"mondo_id","subj":"T189","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A190","pred":"mondo_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A191","pred":"mondo_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A192","pred":"mondo_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A193","pred":"mondo_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A194","pred":"mondo_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A195","pred":"mondo_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A196","pred":"mondo_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A198","pred":"mondo_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A200","pred":"mondo_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A201","pred":"mondo_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A202","pred":"mondo_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A203","pred":"mondo_id","subj":"T203","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A204","pred":"mondo_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T181","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T182","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T183","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T184","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T185","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T186","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T187","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T188","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T189","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T190","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T191","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T192","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T193","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T194","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T195","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T196","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T198","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T199","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T200","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T201","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T202","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T203","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T204","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T143","span":{"begin":17,"end":28},"obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"T144","span":{"begin":94,"end":99},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T145","span":{"begin":133,"end":137},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T146","span":{"begin":133,"end":137},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T147","span":{"begin":145,"end":147},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T148","span":{"begin":198,"end":202},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T149","span":{"begin":198,"end":202},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T150","span":{"begin":220,"end":230},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T151","span":{"begin":231,"end":236},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T152","span":{"begin":285,"end":290},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T153","span":{"begin":305,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T154","span":{"begin":334,"end":335},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T155","span":{"begin":364,"end":368},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T156","span":{"begin":383,"end":384},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T157","span":{"begin":422,"end":429},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T158","span":{"begin":787,"end":792},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T159","span":{"begin":830,"end":833},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T160","span":{"begin":1199,"end":1210},"obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"T161","span":{"begin":1250,"end":1255},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T162","span":{"begin":1339,"end":1341},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T163","span":{"begin":1407,"end":1420},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T164","span":{"begin":1407,"end":1420},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T165","span":{"begin":1422,"end":1427},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T166","span":{"begin":1422,"end":1427},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T167","span":{"begin":1422,"end":1427},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T168","span":{"begin":1422,"end":1427},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T169","span":{"begin":1429,"end":1435},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T170","span":{"begin":1429,"end":1435},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T171","span":{"begin":1429,"end":1435},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T172","span":{"begin":1441,"end":1450},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"T173","span":{"begin":1441,"end":1450},"obj":"http://www.ebi.ac.uk/efo/EFO_0000834"},{"id":"T174","span":{"begin":1480,"end":1483},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T175","span":{"begin":1664,"end":1665},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T176","span":{"begin":1689,"end":1694},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T177","span":{"begin":1807,"end":1812},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T178","span":{"begin":1813,"end":1830},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T179","span":{"begin":1840,"end":1845},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T180","span":{"begin":1846,"end":1858},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T181","span":{"begin":1846,"end":1858},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T182","span":{"begin":1893,"end":1898},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T183","span":{"begin":2000,"end":2005},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T184","span":{"begin":2070,"end":2075},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T185","span":{"begin":2109,"end":2110},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T186","span":{"begin":2164,"end":2177},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T187","span":{"begin":2164,"end":2177},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T188","span":{"begin":2223,"end":2228},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T189","span":{"begin":2345,"end":2346},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T190","span":{"begin":2406,"end":2407},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T191","span":{"begin":2578,"end":2579},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T192","span":{"begin":2731,"end":2748},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T193","span":{"begin":2860,"end":2875},"obj":"http://purl.obolibrary.org/obo/PR_000001393"},{"id":"T194","span":{"begin":2911,"end":2919},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T195","span":{"begin":3005,"end":3007},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T196","span":{"begin":3313,"end":3324},"obj":"http://purl.obolibrary.org/obo/UBERON_0001986"},{"id":"T197","span":{"begin":3332,"end":3333},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T198","span":{"begin":3622,"end":3623},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T199","span":{"begin":3708,"end":3714},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T200","span":{"begin":3788,"end":3789},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T201","span":{"begin":3861,"end":3871},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T202","span":{"begin":4108,"end":4109},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T203","span":{"begin":4148,"end":4149},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T204","span":{"begin":4321,"end":4338},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T205","span":{"begin":4381,"end":4385},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T206","span":{"begin":4381,"end":4385},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T207","span":{"begin":4387,"end":4393},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T208","span":{"begin":4387,"end":4393},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T209","span":{"begin":4387,"end":4393},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T210","span":{"begin":4399,"end":4408},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"T211","span":{"begin":4399,"end":4408},"obj":"http://www.ebi.ac.uk/efo/EFO_0000834"},{"id":"T212","span":{"begin":4484,"end":4501},"obj":"http://purl.obolibrary.org/obo/CL_0000115"},{"id":"T213","span":{"begin":4572,"end":4576},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T214","span":{"begin":4583,"end":4585},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T215","span":{"begin":4606,"end":4607},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T216","span":{"begin":4707,"end":4708},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T143","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T144","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T145","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T146","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T147","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T148","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T149","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T150","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T151","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T152","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T153","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T154","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T155","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T156","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T157","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T158","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T159","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T160","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T161","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T162","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T163","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T164","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T165","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T166","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T167","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T168","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T169","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T175","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T176","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T177","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T178","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T179","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T180","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T181","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T182","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T183","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T184","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T185","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T186","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T187","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T188","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T189","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T190","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T191","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T192","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T193","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T194","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T195","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T196","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T198","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T199","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T200","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T201","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T202","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T203","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T204","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T205","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T206","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T207","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T208","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T209","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T210","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T211","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T212","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T213","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T214","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T215","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T216","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T80","span":{"begin":217,"end":219},"obj":"Chemical"},{"id":"T81","span":{"begin":642,"end":645},"obj":"Chemical"},{"id":"T83","span":{"begin":650,"end":653},"obj":"Chemical"},{"id":"T84","span":{"begin":1985,"end":1996},"obj":"Chemical"},{"id":"T85","span":{"begin":2439,"end":2442},"obj":"Chemical"},{"id":"T86","span":{"begin":2450,"end":2461},"obj":"Chemical"},{"id":"T87","span":{"begin":2484,"end":2498},"obj":"Chemical"},{"id":"T90","span":{"begin":2484,"end":2495},"obj":"Chemical"},{"id":"T91","span":{"begin":2496,"end":2498},"obj":"Chemical"},{"id":"T92","span":{"begin":2502,"end":2513},"obj":"Chemical"},{"id":"T93","span":{"begin":2525,"end":2539},"obj":"Chemical"},{"id":"T96","span":{"begin":2525,"end":2536},"obj":"Chemical"},{"id":"T97","span":{"begin":2537,"end":2539},"obj":"Chemical"},{"id":"T98","span":{"begin":2621,"end":2632},"obj":"Chemical"},{"id":"T99","span":{"begin":2857,"end":2859},"obj":"Chemical"},{"id":"T101","span":{"begin":2877,"end":2879},"obj":"Chemical"},{"id":"T103","span":{"begin":2889,"end":2899},"obj":"Chemical"},{"id":"T104","span":{"begin":2904,"end":2907},"obj":"Chemical"},{"id":"T106","span":{"begin":2936,"end":2943},"obj":"Chemical"},{"id":"T107","span":{"begin":2977,"end":2984},"obj":"Chemical"},{"id":"T108","span":{"begin":2997,"end":3003},"obj":"Chemical"},{"id":"T109","span":{"begin":3143,"end":3152},"obj":"Chemical"},{"id":"T110","span":{"begin":3191,"end":3199},"obj":"Chemical"},{"id":"T111","span":{"begin":3522,"end":3536},"obj":"Chemical"},{"id":"T112","span":{"begin":3598,"end":3600},"obj":"Chemical"},{"id":"T113","span":{"begin":3976,"end":3978},"obj":"Chemical"},{"id":"T114","span":{"begin":4023,"end":4037},"obj":"Chemical"},{"id":"T115","span":{"begin":4039,"end":4046},"obj":"Chemical"},{"id":"T116","span":{"begin":4073,"end":4090},"obj":"Chemical"},{"id":"T117","span":{"begin":4081,"end":4090},"obj":"Chemical"}],"attributes":[{"id":"A80","pred":"chebi_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A81","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_15422"},{"id":"A82","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_30616"},{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_16991"},{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_63620"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A87","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_2719"},{"id":"A88","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_48432"},{"id":"A89","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_58506"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A91","pred":"chebi_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A92","pred":"chebi_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A93","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_2719"},{"id":"A94","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_48432"},{"id":"A95","pred":"chebi_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/CHEBI_58506"},{"id":"A96","pred":"chebi_id","subj":"T96","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A97","pred":"chebi_id","subj":"T97","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A98","pred":"chebi_id","subj":"T98","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A99","pred":"chebi_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A100","pred":"chebi_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A101","pred":"chebi_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A102","pred":"chebi_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A103","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A104","pred":"chebi_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/CHEBI_132592"},{"id":"A105","pred":"chebi_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/CHEBI_50099"},{"id":"A106","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_138157"},{"id":"A109","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_50249"},{"id":"A112","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_74862"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_74862"},{"id":"A114","pred":"chebi_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/CHEBI_50249"},{"id":"A115","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_16541"},{"id":"A116","pred":"chebi_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/CHEBI_76932"},{"id":"A117","pred":"chebi_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T84","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T85","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T86","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T87","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T90","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T91","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T92","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T93","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T96","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T97","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T103","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T104","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T106","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T108","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T109","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T116","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T117","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T38","span":{"begin":1100,"end":1114},"obj":"Phenotype"},{"id":"T39","span":{"begin":3677,"end":3684},"obj":"Phenotype"},{"id":"T40","span":{"begin":3755,"end":3762},"obj":"Phenotype"},{"id":"T41","span":{"begin":3841,"end":3848},"obj":"Phenotype"},{"id":"T42","span":{"begin":3881,"end":3888},"obj":"Phenotype"}],"attributes":[{"id":"A38","pred":"hp_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/HP_0033041"},{"id":"A39","pred":"hp_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"id":"A40","pred":"hp_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"id":"A41","pred":"hp_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"id":"A42","pred":"hp_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/HP_0012418"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T38","span":{"begin":322,"end":332},"obj":"http://purl.obolibrary.org/obo/GO_0070269"},{"id":"T39","span":{"begin":364,"end":374},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T40","span":{"begin":1062,"end":1075},"obj":"http://purl.obolibrary.org/obo/GO_0045087"},{"id":"T41","span":{"begin":1323,"end":1338},"obj":"http://purl.obolibrary.org/obo/GO_0006955"},{"id":"T42","span":{"begin":2051,"end":2066},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T43","span":{"begin":2154,"end":2160},"obj":"http://purl.obolibrary.org/obo/GO_0098739"},{"id":"T44","span":{"begin":2154,"end":2160},"obj":"http://purl.obolibrary.org/obo/GO_0098657"},{"id":"T45","span":{"begin":2197,"end":2203},"obj":"http://purl.obolibrary.org/obo/GO_0098739"},{"id":"T46","span":{"begin":2197,"end":2203},"obj":"http://purl.obolibrary.org/obo/GO_0098657"},{"id":"T47","span":{"begin":2548,"end":2564},"obj":"http://purl.obolibrary.org/obo/GO_0042310"},{"id":"T48","span":{"begin":3899,"end":3920},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T49","span":{"begin":3899,"end":3912},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T50","span":{"begin":4555,"end":4567},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T51","span":{"begin":4572,"end":4582},"obj":"http://purl.obolibrary.org/obo/GO_0008219"}],"attributes":[{"subj":"T38","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T76","span":{"begin":0,"end":73},"obj":"Sentence"},{"id":"T77","span":{"begin":74,"end":430},"obj":"Sentence"},{"id":"T78","span":{"begin":431,"end":1145},"obj":"Sentence"},{"id":"T79","span":{"begin":1146,"end":1730},"obj":"Sentence"},{"id":"T80","span":{"begin":1731,"end":1831},"obj":"Sentence"},{"id":"T81","span":{"begin":1832,"end":2178},"obj":"Sentence"},{"id":"T82","span":{"begin":2179,"end":2518},"obj":"Sentence"},{"id":"T83","span":{"begin":2519,"end":2765},"obj":"Sentence"},{"id":"T84","span":{"begin":2766,"end":3685},"obj":"Sentence"},{"id":"T85","span":{"begin":3686,"end":4147},"obj":"Sentence"},{"id":"T86","span":{"begin":4148,"end":4368},"obj":"Sentence"},{"id":"T87","span":{"begin":4369,"end":4731},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T76","pred":"source","obj":"LitCovid-sentences"},{"subj":"T77","pred":"source","obj":"LitCovid-sentences"},{"subj":"T78","pred":"source","obj":"LitCovid-sentences"},{"subj":"T79","pred":"source","obj":"LitCovid-sentences"},{"subj":"T80","pred":"source","obj":"LitCovid-sentences"},{"subj":"T81","pred":"source","obj":"LitCovid-sentences"},{"subj":"T82","pred":"source","obj":"LitCovid-sentences"},{"subj":"T83","pred":"source","obj":"LitCovid-sentences"},{"subj":"T84","pred":"source","obj":"LitCovid-sentences"},{"subj":"T85","pred":"source","obj":"LitCovid-sentences"},{"subj":"T86","pred":"source","obj":"LitCovid-sentences"},{"subj":"T87","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32586214-32155444-21597698","span":{"begin":248,"end":249},"obj":"32155444"},{"id":"32586214-32015507-21597699","span":{"begin":250,"end":251},"obj":"32015507"},{"id":"32586214-32142651-21597700","span":{"begin":252,"end":253},"obj":"32142651"},{"id":"32586214-32346093-21597701","span":{"begin":804,"end":806},"obj":"32346093"},{"id":"32586214-32361001-21597702","span":{"begin":992,"end":994},"obj":"32361001"},{"id":"32586214-32325026-21597703","span":{"begin":1339,"end":1341},"obj":"32325026"},{"id":"32586214-12075344-21597704","span":{"begin":1451,"end":1453},"obj":"12075344"},{"id":"32586214-16514079-21597705","span":{"begin":1454,"end":1456},"obj":"16514079"},{"id":"32586214-32243607-21597706","span":{"begin":1553,"end":1555},"obj":"32243607"},{"id":"32586214-32333836-21597707","span":{"begin":1966,"end":1968},"obj":"32333836"},{"id":"32586214-32125455-21597708","span":{"begin":2287,"end":2289},"obj":"32125455"},{"id":"32586214-32336612-21597709","span":{"begin":2290,"end":2292},"obj":"32336612"},{"id":"32586214-32336612-21597710","span":{"begin":2763,"end":2765},"obj":"32336612"},{"id":"32586214-31986264-21597711","span":{"begin":3005,"end":3007},"obj":"31986264"},{"id":"32586214-9517590-21597712","span":{"begin":3297,"end":3299},"obj":"9517590"},{"id":"32586214-12543869-21597713","span":{"begin":3300,"end":3302},"obj":"12543869"},{"id":"32586214-9657750-21597714","span":{"begin":3435,"end":3437},"obj":"9657750"},{"id":"32586214-7507411-21597715","span":{"begin":3438,"end":3440},"obj":"7507411"},{"id":"32586214-12543869-21597716","span":{"begin":3609,"end":3611},"obj":"12543869"},{"id":"32586214-31376606-21597717","span":{"begin":4145,"end":4147},"obj":"31376606"},{"id":"32586214-32325026-21597718","span":{"begin":4583,"end":4585},"obj":"32325026"},{"id":"32586214-32333836-21597719","span":{"begin":4729,"end":4731},"obj":"32333836"}],"attributes":[{"subj":"32586214-32155444-21597698","pred":"source","obj":"2_test"},{"subj":"32586214-32015507-21597699","pred":"source","obj":"2_test"},{"subj":"32586214-32142651-21597700","pred":"source","obj":"2_test"},{"subj":"32586214-32346093-21597701","pred":"source","obj":"2_test"},{"subj":"32586214-32361001-21597702","pred":"source","obj":"2_test"},{"subj":"32586214-32325026-21597703","pred":"source","obj":"2_test"},{"subj":"32586214-12075344-21597704","pred":"source","obj":"2_test"},{"subj":"32586214-16514079-21597705","pred":"source","obj":"2_test"},{"subj":"32586214-32243607-21597706","pred":"source","obj":"2_test"},{"subj":"32586214-32333836-21597707","pred":"source","obj":"2_test"},{"subj":"32586214-32125455-21597708","pred":"source","obj":"2_test"},{"subj":"32586214-32336612-21597709","pred":"source","obj":"2_test"},{"subj":"32586214-32336612-21597710","pred":"source","obj":"2_test"},{"subj":"32586214-31986264-21597711","pred":"source","obj":"2_test"},{"subj":"32586214-9517590-21597712","pred":"source","obj":"2_test"},{"subj":"32586214-12543869-21597713","pred":"source","obj":"2_test"},{"subj":"32586214-9657750-21597714","pred":"source","obj":"2_test"},{"subj":"32586214-7507411-21597715","pred":"source","obj":"2_test"},{"subj":"32586214-12543869-21597716","pred":"source","obj":"2_test"},{"subj":"32586214-31376606-21597717","pred":"source","obj":"2_test"},{"subj":"32586214-32325026-21597718","pred":"source","obj":"2_test"},{"subj":"32586214-32333836-21597719","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"693","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"708","span":{"begin":179,"end":184},"obj":"Gene"},{"id":"709","span":{"begin":921,"end":926},"obj":"Gene"},{"id":"710","span":{"begin":931,"end":936},"obj":"Gene"},{"id":"711","span":{"begin":94,"end":99},"obj":"Species"},{"id":"712","span":{"begin":115,"end":125},"obj":"Species"},{"id":"713","span":{"begin":819,"end":829},"obj":"Species"},{"id":"714","span":{"begin":960,"end":968},"obj":"Species"},{"id":"715","span":{"begin":983,"end":991},"obj":"Species"},{"id":"716","span":{"begin":1014,"end":1024},"obj":"Species"},{"id":"717","span":{"begin":642,"end":645},"obj":"Chemical"},{"id":"718","span":{"begin":100,"end":109},"obj":"Disease"},{"id":"719","span":{"begin":296,"end":304},"obj":"Disease"},{"id":"720","span":{"begin":369,"end":374},"obj":"Disease"},{"id":"721","span":{"begin":1136,"end":1144},"obj":"Disease"},{"id":"742","span":{"begin":1342,"end":1347},"obj":"Gene"},{"id":"743","span":{"begin":1647,"end":1652},"obj":"Gene"},{"id":"744","span":{"begin":2026,"end":2031},"obj":"Gene"},{"id":"745","span":{"begin":2139,"end":2144},"obj":"Gene"},{"id":"746","span":{"begin":2270,"end":2275},"obj":"Gene"},{"id":"747","span":{"begin":2394,"end":2399},"obj":"Gene"},{"id":"748","span":{"begin":2484,"end":2498},"obj":"Gene"},{"id":"749","span":{"begin":2525,"end":2539},"obj":"Gene"},{"id":"750","span":{"begin":1530,"end":1538},"obj":"Species"},{"id":"751","span":{"begin":1807,"end":1812},"obj":"Species"},{"id":"752","span":{"begin":1840,"end":1845},"obj":"Species"},{"id":"753","span":{"begin":1893,"end":1898},"obj":"Species"},{"id":"754","span":{"begin":2000,"end":2005},"obj":"Species"},{"id":"755","span":{"begin":2070,"end":2075},"obj":"Species"},{"id":"756","span":{"begin":2207,"end":2217},"obj":"Species"},{"id":"757","span":{"begin":1164,"end":1184},"obj":"Disease"},{"id":"758","span":{"begin":1544,"end":1552},"obj":"Disease"},{"id":"759","span":{"begin":1788,"end":1796},"obj":"Disease"},{"id":"760","span":{"begin":1948,"end":1956},"obj":"Disease"},{"id":"761","span":{"begin":2051,"end":2066},"obj":"Disease"},{"id":"790","span":{"begin":2857,"end":2875},"obj":"Gene"},{"id":"791","span":{"begin":2877,"end":2882},"obj":"Gene"},{"id":"792","span":{"begin":2884,"end":2887},"obj":"Gene"},{"id":"793","span":{"begin":2889,"end":2902},"obj":"Gene"},{"id":"794","span":{"begin":2904,"end":2909},"obj":"Gene"},{"id":"795","span":{"begin":2911,"end":2945},"obj":"Gene"},{"id":"796","span":{"begin":2991,"end":2995},"obj":"Gene"},{"id":"797","span":{"begin":2997,"end":3003},"obj":"Gene"},{"id":"798","span":{"begin":3113,"end":3116},"obj":"Gene"},{"id":"799","span":{"begin":3168,"end":3202},"obj":"Gene"},{"id":"800","span":{"begin":3204,"end":3217},"obj":"Gene"},{"id":"801","span":{"begin":3226,"end":3236},"obj":"Gene"},{"id":"802","span":{"begin":3598,"end":3600},"obj":"Gene"},{"id":"803","span":{"begin":3602,"end":3607},"obj":"Gene"},{"id":"804","span":{"begin":4053,"end":4057},"obj":"Gene"},{"id":"805","span":{"begin":4059,"end":4090},"obj":"Gene"},{"id":"806","span":{"begin":2781,"end":2789},"obj":"Species"},{"id":"807","span":{"begin":2795,"end":2805},"obj":"Species"},{"id":"808","span":{"begin":3642,"end":3650},"obj":"Species"},{"id":"809","span":{"begin":2948,"end":2951},"obj":"Gene"},{"id":"810","span":{"begin":3583,"end":3596},"obj":"Gene"},{"id":"811","span":{"begin":3656,"end":3664},"obj":"Disease"},{"id":"812","span":{"begin":3677,"end":3684},"obj":"Disease"},{"id":"813","span":{"begin":3733,"end":3753},"obj":"Disease"},{"id":"814","span":{"begin":3755,"end":3762},"obj":"Disease"},{"id":"815","span":{"begin":3841,"end":3848},"obj":"Disease"},{"id":"816","span":{"begin":3875,"end":3879},"obj":"Disease"},{"id":"817","span":{"begin":3881,"end":3888},"obj":"Disease"},{"id":"827","span":{"begin":4194,"end":4202},"obj":"Species"},{"id":"828","span":{"begin":4414,"end":4422},"obj":"Species"},{"id":"829","span":{"begin":4208,"end":4216},"obj":"Disease"},{"id":"830","span":{"begin":4302,"end":4310},"obj":"Disease"},{"id":"831","span":{"begin":4349,"end":4367},"obj":"Disease"},{"id":"832","span":{"begin":4428,"end":4436},"obj":"Disease"},{"id":"833","span":{"begin":4555,"end":4567},"obj":"Disease"},{"id":"834","span":{"begin":4577,"end":4582},"obj":"Disease"},{"id":"835","span":{"begin":4623,"end":4631},"obj":"Disease"}],"attributes":[{"id":"A693","pred":"tao:has_database_id","subj":"693","obj":"MESH:C000657245"},{"id":"A708","pred":"tao:has_database_id","subj":"708","obj":"Gene:59272"},{"id":"A709","pred":"tao:has_database_id","subj":"709","obj":"Gene:51284"},{"id":"A710","pred":"tao:has_database_id","subj":"710","obj":"Gene:51311"},{"id":"A711","pred":"tao:has_database_id","subj":"711","obj":"Tax:9606"},{"id":"A712","pred":"tao:has_database_id","subj":"712","obj":"Tax:2697049"},{"id":"A713","pred":"tao:has_database_id","subj":"713","obj":"Tax:2697049"},{"id":"A714","pred":"tao:has_database_id","subj":"714","obj":"Tax:1335626"},{"id":"A715","pred":"tao:has_database_id","subj":"715","obj":"Tax:694009"},{"id":"A716","pred":"tao:has_database_id","subj":"716","obj":"Tax:2697049"},{"id":"A717","pred":"tao:has_database_id","subj":"717","obj":"MESH:D000255"},{"id":"A718","pred":"tao:has_database_id","subj":"718","obj":"MESH:D007239"},{"id":"A719","pred":"tao:has_database_id","subj":"719","obj":"MESH:D007239"},{"id":"A720","pred":"tao:has_database_id","subj":"720","obj":"MESH:D003643"},{"id":"A721","pred":"tao:has_database_id","subj":"721","obj":"MESH:C000657245"},{"id":"A742","pred":"tao:has_database_id","subj":"742","obj":"Gene:59272"},{"id":"A743","pred":"tao:has_database_id","subj":"743","obj":"Gene:59272"},{"id":"A744","pred":"tao:has_database_id","subj":"744","obj":"Gene:59272"},{"id":"A745","pred":"tao:has_database_id","subj":"745","obj":"Gene:59272"},{"id":"A746","pred":"tao:has_database_id","subj":"746","obj":"Gene:59272"},{"id":"A747","pred":"tao:has_database_id","subj":"747","obj":"Gene:59272"},{"id":"A748","pred":"tao:has_database_id","subj":"748","obj":"Gene:183"},{"id":"A749","pred":"tao:has_database_id","subj":"749","obj":"Gene:183"},{"id":"A750","pred":"tao:has_database_id","subj":"750","obj":"Tax:9606"},{"id":"A751","pred":"tao:has_database_id","subj":"751","obj":"Tax:9606"},{"id":"A752","pred":"tao:has_database_id","subj":"752","obj":"Tax:9606"},{"id":"A753","pred":"tao:has_database_id","subj":"753","obj":"Tax:9606"},{"id":"A754","pred":"tao:has_database_id","subj":"754","obj":"Tax:9606"},{"id":"A755","pred":"tao:has_database_id","subj":"755","obj":"Tax:9606"},{"id":"A756","pred":"tao:has_database_id","subj":"756","obj":"Tax:2697049"},{"id":"A757","pred":"tao:has_database_id","subj":"757","obj":"MESH:C000657245"},{"id":"A758","pred":"tao:has_database_id","subj":"758","obj":"MESH:C000657245"},{"id":"A759","pred":"tao:has_database_id","subj":"759","obj":"MESH:C000657245"},{"id":"A760","pred":"tao:has_database_id","subj":"760","obj":"MESH:C000657245"},{"id":"A761","pred":"tao:has_database_id","subj":"761","obj":"MESH:D001102"},{"id":"A790","pred":"tao:has_database_id","subj":"790","obj":"Gene:3569"},{"id":"A791","pred":"tao:has_database_id","subj":"791","obj":"Gene:3552"},{"id":"A792","pred":"tao:has_database_id","subj":"792","obj":"Gene:3439"},{"id":"A793","pred":"tao:has_database_id","subj":"793","obj":"Gene:3458"},{"id":"A794","pred":"tao:has_database_id","subj":"794","obj":"Gene:6347"},{"id":"A795","pred":"tao:has_database_id","subj":"795","obj":"Gene:6347"},{"id":"A796","pred":"tao:has_database_id","subj":"796","obj":"Gene:3627"},{"id":"A797","pred":"tao:has_database_id","subj":"797","obj":"Gene:3627"},{"id":"A798","pred":"tao:has_database_id","subj":"798","obj":"Gene:7450"},{"id":"A799","pred":"tao:has_database_id","subj":"799","obj":"Gene:3383"},{"id":"A800","pred":"tao:has_database_id","subj":"800","obj":"Gene:3685"},{"id":"A801","pred":"tao:has_database_id","subj":"801","obj":"Gene:6401"},{"id":"A802","pred":"tao:has_database_id","subj":"802","obj":"Gene:2152"},{"id":"A803","pred":"tao:has_database_id","subj":"803","obj":"Gene:2152"},{"id":"A804","pred":"tao:has_database_id","subj":"804","obj":"Gene:7035"},{"id":"A805","pred":"tao:has_database_id","subj":"805","obj":"Gene:7035"},{"id":"A806","pred":"tao:has_database_id","subj":"806","obj":"Tax:9606"},{"id":"A807","pred":"tao:has_database_id","subj":"807","obj":"Tax:2697049"},{"id":"A808","pred":"tao:has_database_id","subj":"808","obj":"Tax:9606"},{"id":"A809","pred":"tao:has_database_id","subj":"809","obj":"Gene:4284"},{"id":"A810","pred":"tao:has_database_id","subj":"810","obj":"Gene:2152"},{"id":"A811","pred":"tao:has_database_id","subj":"811","obj":"MESH:C000657245"},{"id":"A812","pred":"tao:has_database_id","subj":"812","obj":"MESH:D000860"},{"id":"A813","pred":"tao:has_database_id","subj":"813","obj":"MESH:C000657245"},{"id":"A814","pred":"tao:has_database_id","subj":"814","obj":"MESH:D000860"},{"id":"A815","pred":"tao:has_database_id","subj":"815","obj":"MESH:D000860"},{"id":"A817","pred":"tao:has_database_id","subj":"817","obj":"MESH:D000860"},{"id":"A827","pred":"tao:has_database_id","subj":"827","obj":"Tax:9606"},{"id":"A828","pred":"tao:has_database_id","subj":"828","obj":"Tax:9606"},{"id":"A829","pred":"tao:has_database_id","subj":"829","obj":"MESH:C000657245"},{"id":"A830","pred":"tao:has_database_id","subj":"830","obj":"MESH:C000657245"},{"id":"A831","pred":"tao:has_database_id","subj":"831","obj":"MESH:D014947"},{"id":"A832","pred":"tao:has_database_id","subj":"832","obj":"MESH:C000657245"},{"id":"A833","pred":"tao:has_database_id","subj":"833","obj":"MESH:D007249"},{"id":"A834","pred":"tao:has_database_id","subj":"834","obj":"MESH:D003643"},{"id":"A835","pred":"tao:has_database_id","subj":"835","obj":"MESH:C000657245"},{"subj":"693","pred":"source","obj":"LitCovid-PubTator"},{"subj":"708","pred":"source","obj":"LitCovid-PubTator"},{"subj":"709","pred":"source","obj":"LitCovid-PubTator"},{"subj":"710","pred":"source","obj":"LitCovid-PubTator"},{"subj":"711","pred":"source","obj":"LitCovid-PubTator"},{"subj":"712","pred":"source","obj":"LitCovid-PubTator"},{"subj":"713","pred":"source","obj":"LitCovid-PubTator"},{"subj":"714","pred":"source","obj":"LitCovid-PubTator"},{"subj":"715","pred":"source","obj":"LitCovid-PubTator"},{"subj":"716","pred":"source","obj":"LitCovid-PubTator"},{"subj":"717","pred":"source","obj":"LitCovid-PubTator"},{"subj":"718","pred":"source","obj":"LitCovid-PubTator"},{"subj":"719","pred":"source","obj":"LitCovid-PubTator"},{"subj":"720","pred":"source","obj":"LitCovid-PubTator"},{"subj":"721","pred":"source","obj":"LitCovid-PubTator"},{"subj":"742","pred":"source","obj":"LitCovid-PubTator"},{"subj":"743","pred":"source","obj":"LitCovid-PubTator"},{"subj":"744","pred":"source","obj":"LitCovid-PubTator"},{"subj":"745","pred":"source","obj":"LitCovid-PubTator"},{"subj":"746","pred":"source","obj":"LitCovid-PubTator"},{"subj":"747","pred":"source","obj":"LitCovid-PubTator"},{"subj":"748","pred":"source","obj":"LitCovid-PubTator"},{"subj":"749","pred":"source","obj":"LitCovid-PubTator"},{"subj":"750","pred":"source","obj":"LitCovid-PubTator"},{"subj":"751","pred":"source","obj":"LitCovid-PubTator"},{"subj":"752","pred":"source","obj":"LitCovid-PubTator"},{"subj":"753","pred":"source","obj":"LitCovid-PubTator"},{"subj":"754","pred":"source","obj":"LitCovid-PubTator"},{"subj":"755","pred":"source","obj":"LitCovid-PubTator"},{"subj":"756","pred":"source","obj":"LitCovid-PubTator"},{"subj":"757","pred":"source","obj":"LitCovid-PubTator"},{"subj":"758","pred":"source","obj":"LitCovid-PubTator"},{"subj":"759","pred":"source","obj":"LitCovid-PubTator"},{"subj":"760","pred":"source","obj":"LitCovid-PubTator"},{"subj":"761","pred":"source","obj":"LitCovid-PubTator"},{"subj":"790","pred":"source","obj":"LitCovid-PubTator"},{"subj":"791","pred":"source","obj":"LitCovid-PubTator"},{"subj":"792","pred":"source","obj":"LitCovid-PubTator"},{"subj":"793","pred":"source","obj":"LitCovid-PubTator"},{"subj":"794","pred":"source","obj":"LitCovid-PubTator"},{"subj":"795","pred":"source","obj":"LitCovid-PubTator"},{"subj":"796","pred":"source","obj":"LitCovid-PubTator"},{"subj":"797","pred":"source","obj":"LitCovid-PubTator"},{"subj":"798","pred":"source","obj":"LitCovid-PubTator"},{"subj":"799","pred":"source","obj":"LitCovid-PubTator"},{"subj":"800","pred":"source","obj":"LitCovid-PubTator"},{"subj":"801","pred":"source","obj":"LitCovid-PubTator"},{"subj":"802","pred":"source","obj":"LitCovid-PubTator"},{"subj":"803","pred":"source","obj":"LitCovid-PubTator"},{"subj":"804","pred":"source","obj":"LitCovid-PubTator"},{"subj":"805","pred":"source","obj":"LitCovid-PubTator"},{"subj":"806","pred":"source","obj":"LitCovid-PubTator"},{"subj":"807","pred":"source","obj":"LitCovid-PubTator"},{"subj":"808","pred":"source","obj":"LitCovid-PubTator"},{"subj":"809","pred":"source","obj":"LitCovid-PubTator"},{"subj":"810","pred":"source","obj":"LitCovid-PubTator"},{"subj":"811","pred":"source","obj":"LitCovid-PubTator"},{"subj":"812","pred":"source","obj":"LitCovid-PubTator"},{"subj":"813","pred":"source","obj":"LitCovid-PubTator"},{"subj":"814","pred":"source","obj":"LitCovid-PubTator"},{"subj":"815","pred":"source","obj":"LitCovid-PubTator"},{"subj":"816","pred":"source","obj":"LitCovid-PubTator"},{"subj":"817","pred":"source","obj":"LitCovid-PubTator"},{"subj":"827","pred":"source","obj":"LitCovid-PubTator"},{"subj":"828","pred":"source","obj":"LitCovid-PubTator"},{"subj":"829","pred":"source","obj":"LitCovid-PubTator"},{"subj":"830","pred":"source","obj":"LitCovid-PubTator"},{"subj":"831","pred":"source","obj":"LitCovid-PubTator"},{"subj":"832","pred":"source","obj":"LitCovid-PubTator"},{"subj":"833","pred":"source","obj":"LitCovid-PubTator"},{"subj":"834","pred":"source","obj":"LitCovid-PubTator"},{"subj":"835","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ece793","default":true},{"id":"LitCovid-PD-UBERON","color":"#cd93ec"},{"id":"LitCovid-PD-MONDO","color":"#93ecb3"},{"id":"LitCovid-PD-CLO","color":"#ec9993"},{"id":"LitCovid-PD-CHEBI","color":"#93a7ec"},{"id":"LitCovid-PD-HP","color":"#c1ec93"},{"id":"LitCovid-PD-GO-BP","color":"#ec93db"},{"id":"LitCovid-sentences","color":"#93ece3"},{"id":"2_test","color":"#ecc993"},{"id":"LitCovid-PubTator","color":"#af93ec"}]}]}}