PMC:7386875 / 17005-17989
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T104 | 449-457 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
T105 | 458-467 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
T106 | 625-633 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
T107 | 656-664 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
T108 | 726-747 | Body_part | denotes | pulmonary vasculature | http://purl.org/sig/ont/fma/fma73750 |
T109 | 777-782 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T18 | 458-467 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
T19 | 736-747 | Body_part | denotes | vasculature | http://purl.obolibrary.org/obo/UBERON_0002049 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T167 | 24-34 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
T168 | 106-110 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T169 | 160-164 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T170 | 216-224 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T171 | 300-308 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T172 | 311-320 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T173 | 356-364 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T174 | 376-395 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
T175 | 514-523 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T176 | 650-654 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T177 | 957-965 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T130 | 35-38 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T131 | 81-82 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T132 | 115-118 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T133 | 238-240 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
T134 | 241-243 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
T135 | 410-413 | http://purl.obolibrary.org/obo/CLO_0001618 | denotes | a 9 |
T136 | 410-413 | http://purl.obolibrary.org/obo/CLO_0001619 | denotes | a 9 |
T137 | 410-413 | http://purl.obolibrary.org/obo/CLO_0001620 | denotes | a 9 |
T138 | 684-685 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T139 | 777-782 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T140 | 806-808 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T141 | 924-925 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T35 | 293-320 | Phenotype | denotes | severe SARS-CoV-2 infection | http://purl.obolibrary.org/obo/HP_0033141 |
T36 | 376-395 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
T37 | 617-640 | Phenotype | denotes | diffuse alveolar damage | http://purl.obolibrary.org/obo/HP_0033006 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T37 | 972-983 | http://purl.obolibrary.org/obo/GO_0050817 | denotes | coagulation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T74 | 0-984 | Sentence | denotes | Pulmonary microvascular thrombosis has been previously described in autopsies as a complication of severe ARDS and has subsequently been reported to complicate ARDS during outbreaks of other coronaviruses, including SARS-CoV and MERS-CoV.36–41 However, this feature appears more pronounced in severe SARS-CoV-2 infection, with histology from patients with COVID-19-associated respiratory failure demonstrating a 9-fold increase in the prevalence of alveolar-capillary microthrombi when compared with patients with influenza.42 In this regard, autopsy findings have shown that, in addition to the expected features of diffuse alveolar damage found in ARDS, platelet-fibrin thrombi are a common microscopic finding in the small pulmonary vasculature, occurring in 80% to 100% of lungs examined at autopsy.43–45 In combination with other reported thrombotic events, the emerging microvascular thrombotic complications indicate a strong interaction between the SARS-CoV-2 and coagulation. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32586214-14660106-21597696 | 238-240 | 14660106 | denotes | 36 |
32586214-12845623-21597696 | 238-240 | 12845623 | denotes | 36 |
32586214-15272286-21597696 | 238-240 | 15272286 | denotes | 36 |
32586214-14506633-21597696 | 238-240 | 14506633 | denotes | 36 |
32586214-26486634-21597696 | 238-240 | 26486634 | denotes | 36 |
32586214-6859225-21597696 | 238-240 | 6859225 | denotes | 36 |
32586214-32294295-21597697 | 803-805 | 32294295 | denotes | 43 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
669 | 191-204 | Species | denotes | coronaviruses | Tax:11118 |
670 | 216-224 | Species | denotes | SARS-CoV | Tax:694009 |
671 | 229-237 | Species | denotes | MERS-CoV | Tax:1335626 |
672 | 342-350 | Species | denotes | patients | Tax:9606 |
673 | 500-508 | Species | denotes | patients | Tax:9606 |
674 | 957-967 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
676 | 514-523 | Species | denotes | influenza | Tax:11309 |
679 | 0-34 | Disease | denotes | Pulmonary microvascular thrombosis | MESH:D013927 |
680 | 106-110 | Disease | denotes | ARDS | MESH:D012128 |
681 | 160-164 | Disease | denotes | ARDS | MESH:D012128 |
682 | 300-320 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
683 | 356-364 | Disease | denotes | COVID-19 | MESH:C000657245 |
684 | 376-395 | Disease | denotes | respiratory failure | MESH:D012131 |
685 | 625-640 | Disease | denotes | alveolar damage | MESH:D055370 |
686 | 650-654 | Disease | denotes | ARDS | MESH:D012128 |
687 | 672-679 | Disease | denotes | thrombi | MESH:D013927 |
688 | 844-854 | Disease | denotes | thrombotic | MESH:D013927 |
689 | 890-900 | Disease | denotes | thrombotic | MESH:D013927 |