PMC:7386875 / 136-1279
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 644-661 | Body_part | denotes | endothelial cells | http://purl.org/sig/ont/fma/fma66772 |
T2 | 656-661 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T3 | 733-749 | Body_part | denotes | endothelial cell | http://purl.org/sig/ont/fma/fma66772 |
T4 | 745-749 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T5 | 879-887 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
T6 | 893-902 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
T7 | 1071-1075 | Body_part | denotes | vein | http://purl.org/sig/ont/fma/fma50723 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1066-1075 | Body_part | denotes | deep vein | http://purl.obolibrary.org/obo/UBERON_0035552 |
T2 | 1071-1075 | Body_part | denotes | vein | http://purl.obolibrary.org/obo/UBERON_0001638 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T5 | 33-41 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T6 | 180-204 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T7 | 206-214 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T8 | 309-319 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
T9 | 321-342 | Disease | denotes | venous thromboembolic | http://purl.obolibrary.org/obo/MONDO_0005399 |
T10 | 356-362 | Disease | denotes | stroke | http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057 |
T12 | 424-432 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 457-475 | Disease | denotes | multiorgan failure | http://purl.obolibrary.org/obo/MONDO_0043726 |
T14 | 588-596 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T15 | 623-631 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T16 | 785-793 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 821-833 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T18 | 1076-1086 | Disease | denotes | thrombosis | http://purl.obolibrary.org/obo/MONDO_0000831 |
T19 | 1088-1106 | Disease | denotes | pulmonary embolism | http://purl.obolibrary.org/obo/MONDO_0005279 |
T20 | 1112-1118 | Disease | denotes | stroke | http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 77-80 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T2 | 91-92 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T3 | 159-162 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T4 | 235-236 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T5 | 644-661 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cells |
T6 | 733-749 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cell |
T7 | 846-856 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T8 | 1071-1075 | http://purl.obolibrary.org/obo/UBERON_0001638 | denotes | vein |
T9 | 1071-1075 | http://www.ebi.ac.uk/efo/EFO_0000816 | denotes | vein |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 673-684 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 328-350 | Phenotype | denotes | thromboembolic disease | http://purl.obolibrary.org/obo/HP_0001907 |
T2 | 356-362 | Phenotype | denotes | stroke | http://purl.obolibrary.org/obo/HP_0001297 |
T3 | 1066-1086 | Phenotype | denotes | deep vein thrombosis | http://purl.obolibrary.org/obo/HP_0002625 |
T4 | 1088-1106 | Phenotype | denotes | pulmonary embolism | http://purl.obolibrary.org/obo/HP_0002204 |
T5 | 1112-1118 | Phenotype | denotes | stroke | http://purl.obolibrary.org/obo/HP_0001297 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 821-833 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T2 | 835-856 | http://purl.obolibrary.org/obo/GO_0006956 | denotes | complement activation |
T3 | 949-974 | http://purl.obolibrary.org/obo/GO_0002250 | denotes | adaptive immune responses |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4 | 138-363 | Sentence | denotes | Recent clinical data has highlighted that coronavirus disease 2019 (COVID-19) is associated with a significant risk of thrombotic complications ranging from microvascular thrombosis, venous thromboembolic disease, and stroke. |
T5 | 364-500 | Sentence | denotes | Importantly, thrombotic complications are markers of severe COVID-19 and are associated with multiorgan failure and increased mortality. |
T6 | 501-758 | Sentence | denotes | The evidence to date supports the concept that the thrombotic manifestations of severe COVID-19 are due to the ability of SARS-CoV-2 to invade endothelial cells via ACE-2 (angiotensin-converting enzyme 2), which is expressed on the endothelial cell surface. |
T7 | 759-1119 | Sentence | denotes | However, in patients with COVID-19 the subsequent endothelial inflammation, complement activation, thrombin generation, platelet, and leukocyte recruitment, and the initiation of innate and adaptive immune responses culminate in immunothrombosis, ultimately causing (micro)thrombotic complications, such as deep vein thrombosis, pulmonary embolism, and stroke. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
48 | 666-671 | Gene | denotes | ACE-2 | Gene:59272 |
49 | 673-704 | Gene | denotes | angiotensin-converting enzyme 2 | Gene:59272 |
50 | 858-866 | Gene | denotes | thrombin | Gene:2147 |
52 | 33-43 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
53 | 623-633 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
54 | 771-779 | Species | denotes | patients | Tax:9606 |
60 | 180-204 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
61 | 206-214 | Disease | denotes | COVID-19 | MESH:C000657245 |
62 | 257-281 | Disease | denotes | thrombotic complications | MESH:D013927 |
63 | 309-319 | Disease | denotes | thrombosis | MESH:D013927 |
64 | 321-350 | Disease | denotes | venous thromboembolic disease | MESH:D054556 |
65 | 356-362 | Disease | denotes | stroke | MESH:D020521 |
66 | 377-401 | Disease | denotes | thrombotic complications | MESH:D013927 |
67 | 424-432 | Disease | denotes | COVID-19 | MESH:C000657245 |
68 | 457-475 | Disease | denotes | multiorgan failure | MESH:D009102 |
69 | 490-499 | Disease | denotes | mortality | MESH:D003643 |
70 | 552-562 | Disease | denotes | thrombotic | MESH:D013927 |
71 | 588-596 | Disease | denotes | COVID-19 | MESH:C000657245 |
72 | 785-793 | Disease | denotes | COVID-19 | MESH:C000657245 |
73 | 821-833 | Disease | denotes | inflammation | MESH:D007249 |
74 | 988-1004 | Disease | denotes | immunothrombosis | |
75 | 1032-1056 | Disease | denotes | thrombotic complications | MESH:D013927 |
76 | 1066-1086 | Disease | denotes | deep vein thrombosis | MESH:D020246 |
77 | 1088-1106 | Disease | denotes | pulmonary embolism | MESH:D011655 |
78 | 1112-1118 | Disease | denotes | stroke | MESH:D020521 |