PMC:7386785 / 74140-76702
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T59 | 0-8 | Body_part | denotes | Appendix | http://purl.org/sig/ont/fma/fma14542 |
| T60 | 454-459 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T61 | 639-644 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T62 | 816-821 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T63 | 1019-1024 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T64 | 1079-1083 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T65 | 1167-1171 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T66 | 2315-2319 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T41 | 454-459 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T42 | 639-644 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T43 | 816-821 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T44 | 1019-1024 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T45 | 1079-1083 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T46 | 1167-1171 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T47 | 2315-2319 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T296 | 63-72 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T297 | 113-134 | Disease | denotes | respiratory infection | http://purl.obolibrary.org/obo/MONDO_0024355 |
| T298 | 125-134 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T299 | 481-490 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T300 | 613-622 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T301 | 885-920 | Disease | denotes | Acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T302 | 891-920 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T303 | 922-926 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T304 | 1227-1246 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T305 | 1270-1285 | Disease | denotes | cardiac failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T306 | 1480-1515 | Disease | denotes | acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T307 | 1486-1515 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T308 | 1517-1521 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T309 | 1759-1763 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T310 | 1846-1850 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T311 | 1973-1977 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T312 | 2059-2061 | Disease | denotes | OI | http://purl.obolibrary.org/obo/MONDO_0019019 |
| T313 | 2372-2376 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T314 | 2406-2408 | Disease | denotes | OI | http://purl.obolibrary.org/obo/MONDO_0019019 |
| T315 | 2440-2444 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T316 | 2474-2481 | Disease | denotes | OI < 16 | http://purl.obolibrary.org/obo/MONDO_0014544 |
| T317 | 2474-2476 | Disease | denotes | OI | http://purl.obolibrary.org/obo/MONDO_0019019 |
| T318 | 2510-2514 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T319 | 2540-2547 | Disease | denotes | OI ≥ 16 | http://purl.obolibrary.org/obo/MONDO_0014544 |
| T320 | 2540-2542 | Disease | denotes | OI | http://purl.obolibrary.org/obo/MONDO_0019019 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T443 | 25-37 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T444 | 454-459 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T445 | 496-497 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T446 | 639-644 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T447 | 725-727 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T448 | 816-821 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T449 | 953-954 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T450 | 1019-1024 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T451 | 1079-1083 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T452 | 1079-1083 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T453 | 1167-1171 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T454 | 1167-1171 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T455 | 1310-1319 | http://purl.obolibrary.org/obo/BFO_0000030 | denotes | objective |
| T456 | 1544-1552 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arterial |
| T457 | 1544-1552 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arterial |
| T458 | 1696-1702 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
| T459 | 2315-2319 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T14 | 233-239 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T15 | 1553-1559 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T16 | 1597-1603 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T17 | 1667-1671 | Chemical | denotes | PEEP | http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683 |
| T19 | 1803-1807 | Chemical | denotes | PEEP | http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683 |
| T21 | 1879-1883 | Chemical | denotes | PEEP | http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T172 | 63-72 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T173 | 94-99 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T174 | 113-134 | Phenotype | denotes | respiratory infection | http://purl.obolibrary.org/obo/HP_0011947 |
| T175 | 208-228 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T176 | 288-293 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T177 | 297-320 | Phenotype | denotes | difficulty in breathing | http://purl.obolibrary.org/obo/HP_0002098 |
| T178 | 366-374 | Phenotype | denotes | cyanosis | http://purl.obolibrary.org/obo/HP_0000961 |
| T179 | 397-417 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T180 | 481-490 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T181 | 553-561 | Phenotype | denotes | lethargy | http://purl.obolibrary.org/obo/HP_0001254 |
| T182 | 613-622 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T183 | 891-911 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T184 | 1204-1225 | Phenotype | denotes | pulmonary infiltrates | http://purl.obolibrary.org/obo/HP_0002113 |
| T185 | 1227-1246 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T186 | 1270-1285 | Phenotype | denotes | cardiac failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T187 | 1407-1413 | Phenotype | denotes | oedema | http://purl.obolibrary.org/obo/HP_0000969 |
| T188 | 1486-1506 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T31 | 311-320 | http://purl.obolibrary.org/obo/GO_0007585 | denotes | breathing |
| T32 | 661-670 | http://purl.obolibrary.org/obo/GO_0007585 | denotes | breathing |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T634 | 0-11 | Sentence | denotes | Appendix 1. |
| T635 | 12-54 | Sentence | denotes | World Health Organization case definitions |
| T636 | 56-72 | Sentence | denotes | Severe pneumonia |
| T637 | 73-276 | Sentence | denotes | Adolescent or adult: fever or suspected respiratory infection, plus one of the following: respiratory rate > 30 breaths/minute; severe respiratory distress; or oxygen saturation (SpO2) ≤ 93% on room air. |
| T638 | 277-597 | Sentence | denotes | Child with cough or difficulty in breathing, plus at least one of the following: central cyanosis or SpO2 < 90%; severe respiratory distress (for example, grunting, very severe chest indrawing); signs of pneumonia with a general danger sign: inability to breastfeed or drink, lethargy or unconsciousness, or convulsions. |
| T639 | 598-766 | Sentence | denotes | Other signs of pneumonia may be present: chest indrawing, fast breathing (in breaths/minute): aged < 2 months: ≥ 60; aged 2 to 11 months: ≥ 50; aged 1 to 5 years: ≥ 40. |
| T640 | 767-883 | Sentence | denotes | While the diagnosis is made on clinical grounds; chest imaging may identify or exclude some pulmonary complications. |
| T641 | 885-927 | Sentence | denotes | Acute respiratory distress syndrome (ARDS) |
| T642 | 928-1018 | Sentence | denotes | Onset within one week of a known clinical insult or new or worsening respiratory symptoms. |
| T643 | 1019-1193 | Sentence | denotes | Chest imaging (that is, X‐ray, computed tomography scan, or lung ultrasound): bilateral opacities, not fully explained by volume overload, lobar or lung collapse, or nodules. |
| T644 | 1194-1304 | Sentence | denotes | Origin of pulmonary infiltrates: respiratory failure not fully explained by cardiac failure or fluid overload. |
| T645 | 1305-1440 | Sentence | denotes | Need objective assessment (for example, echocardiography) to exclude hydrostatic cause of infiltrates/oedema if no risk factor present. |
| T646 | 1441-1474 | Sentence | denotes | Oxygenation impairment in adults: |
| T647 | 1475-1523 | Sentence | denotes | mild acute respiratory distress syndrome (ARDS): |
| T648 | 1524-1749 | Sentence | denotes | 200 mmHg < ratio of arterial oxygen partial pressure/fractional inspired oxygen (PaO2/FiO2) ≤ 300 mmHg (with positive end‐expiratory pressure (PEEP) or continuous positive airway pressure (CPAP) ≥ 5 cmH2O, or non‐ventilated); |
| T649 | 1750-1764 | Sentence | denotes | moderate ARDS: |
| T650 | 1765-1838 | Sentence | denotes | 100 mmHg < PaO2/FiO2 ≤ 200 mmHg (with PEEP ≥ 5 cmH2O, or non‐ventilated); |
| T651 | 1839-1851 | Sentence | denotes | severe ARDS: |
| T652 | 1852-1914 | Sentence | denotes | PaO2/FiO2 ≤ 100 mmHg (with PEEP ≥ 5 cmH2O, or non‐ventilated); |
| T653 | 1915-2017 | Sentence | denotes | when PaO2 is not available, SpO2/FiO2 ≤ 315 mmHg suggests ARDS (including in non‐ventilated patients). |
| T654 | 2018-2121 | Sentence | denotes | Oxygenation impairment in children: note OI = Oxygenation Index and OSI = Oxygenation Index using SpO2. |
| T655 | 2122-2159 | Sentence | denotes | Use PaO2‐based metric when available. |
| T656 | 2160-2252 | Sentence | denotes | If PaO2 not available, wean FiO2 to maintain SpO2 ≤ 97% to calculate OSI or SpO2/FiO2 ratio: |
| T657 | 2253-2325 | Sentence | denotes | bilevel (non‐invasive ventilation or CPAP) ≥ 5 cmH2O via full‐face mask: |
| T658 | 2326-2366 | Sentence | denotes | PaO2/FiO2 ≤ 300 mmHg or SpO2/FiO2 ≤ 264; |
| T659 | 2367-2401 | Sentence | denotes | mild ARDS (invasively ventilated): |
| T660 | 2402-2430 | Sentence | denotes | 4 ≤ OI < 8 or 5 ≤ OSI < 7.5; |
| T661 | 2431-2469 | Sentence | denotes | moderate ARDS (invasively ventilated): |
| T662 | 2470-2502 | Sentence | denotes | 8 ≤ OI < 16 or 7.5 ≤ OSI < 12.3; |
| T663 | 2503-2562 | Sentence | denotes | severe ARDS (invasively ventilated): OI ≥ 16 or OSI ≥ 12.3. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1171 | 63-72 | Disease | denotes | pneumonia | MESH:D011014 |
| 1183 | 277-282 | Species | denotes | Child | Tax:9606 |
| 1184 | 233-239 | Chemical | denotes | oxygen | MESH:D010100 |
| 1185 | 94-99 | Disease | denotes | fever | MESH:D005334 |
| 1186 | 113-134 | Disease | denotes | respiratory infection | MESH:D012141 |
| 1187 | 208-228 | Disease | denotes | respiratory distress | MESH:D012128 |
| 1188 | 288-293 | Disease | denotes | cough | MESH:D003371 |
| 1189 | 366-374 | Disease | denotes | cyanosis | MESH:D003490 |
| 1190 | 397-417 | Disease | denotes | respiratory distress | MESH:D012128 |
| 1191 | 481-490 | Disease | denotes | pneumonia | MESH:D011014 |
| 1192 | 553-561 | Disease | denotes | lethargy | MESH:D053609 |
| 1193 | 585-596 | Disease | denotes | convulsions | MESH:D012640 |
| 1195 | 613-622 | Disease | denotes | pneumonia | MESH:D011014 |
| 1198 | 885-920 | Disease | denotes | Acute respiratory distress syndrome | MESH:D012128 |
| 1199 | 922-926 | Disease | denotes | ARDS | MESH:D012128 |
| 1201 | 997-1017 | Disease | denotes | respiratory symptoms | MESH:D012818 |
| 1205 | 1227-1246 | Disease | denotes | respiratory failure | MESH:D012131 |
| 1206 | 1270-1285 | Disease | denotes | cardiac failure | MESH:D006333 |
| 1207 | 1407-1413 | Disease | denotes | oedema | MESH:D004487 |
| 1212 | 1553-1559 | Chemical | denotes | oxygen | MESH:D010100 |
| 1213 | 1597-1603 | Chemical | denotes | oxygen | MESH:D010100 |
| 1214 | 1480-1515 | Disease | denotes | acute respiratory distress syndrome | MESH:D012128 |
| 1215 | 1517-1521 | Disease | denotes | ARDS | MESH:D012128 |
| 1217 | 1759-1763 | Disease | denotes | ARDS | MESH:D012128 |
| 1219 | 1846-1850 | Disease | denotes | ARDS | MESH:D012128 |
| 1222 | 2007-2015 | Species | denotes | patients | Tax:9606 |
| 1223 | 1973-1977 | Disease | denotes | ARDS | MESH:D012128 |
| 1227 | 2044-2052 | Species | denotes | children | Tax:9606 |
| 1228 | 2188-2192 | Chemical | denotes | FiO2 | |
| 1229 | 2241-2245 | Chemical | denotes | FiO2 | |
| 1231 | 2372-2376 | Disease | denotes | ARDS | MESH:D012128 |
| 1233 | 2440-2444 | Disease | denotes | ARDS | MESH:D012128 |
| 1235 | 2510-2514 | Disease | denotes | ARDS | MESH:D012128 |