PMC:7386785 / 5156-6043 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T27","span":{"begin":563,"end":571},"obj":"Disease"}],"attributes":[{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Authors' conclusions\nThe individual signs and symptoms included in this review appear to have very poor diagnostic properties, although this should be interpreted in the context of selection bias and heterogeneity between studies. Based on currently available data, neither absence nor presence of signs or symptoms are accurate enough to rule in or rule out disease. Prospective studies in an unselected population presenting to primary care or hospital outpatient settings, examining combinations of signs and symptoms to evaluate the syndromic presentation of COVID‐19 disease, are urgently needed. Results from such studies could inform subsequent management decisions such as self‐isolation or selecting patients for further diagnostic testing. We also need data on potentially more specific symptoms such as loss of sense of smell. Studies in older adults are especially important."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T14958","span":{"begin":741,"end":748},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"text":"Authors' conclusions\nThe individual signs and symptoms included in this review appear to have very poor diagnostic properties, although this should be interpreted in the context of selection bias and heterogeneity between studies. Based on currently available data, neither absence nor presence of signs or symptoms are accurate enough to rule in or rule out disease. Prospective studies in an unselected population presenting to primary care or hospital outpatient settings, examining combinations of signs and symptoms to evaluate the syndromic presentation of COVID‐19 disease, are urgently needed. Results from such studies could inform subsequent management decisions such as self‐isolation or selecting patients for further diagnostic testing. We also need data on potentially more specific symptoms such as loss of sense of smell. Studies in older adults are especially important."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T14728","span":{"begin":822,"end":836},"obj":"http://purl.obolibrary.org/obo/GO_0007608"}],"text":"Authors' conclusions\nThe individual signs and symptoms included in this review appear to have very poor diagnostic properties, although this should be interpreted in the context of selection bias and heterogeneity between studies. Based on currently available data, neither absence nor presence of signs or symptoms are accurate enough to rule in or rule out disease. Prospective studies in an unselected population presenting to primary care or hospital outpatient settings, examining combinations of signs and symptoms to evaluate the syndromic presentation of COVID‐19 disease, are urgently needed. Results from such studies could inform subsequent management decisions such as self‐isolation or selecting patients for further diagnostic testing. We also need data on potentially more specific symptoms such as loss of sense of smell. Studies in older adults are especially important."}

{"project":"LitCovid-sentences","denotations":[{"id":"T44","span":{"begin":0,"end":20},"obj":"Sentence"},{"id":"T45","span":{"begin":21,"end":230},"obj":"Sentence"},{"id":"T46","span":{"begin":231,"end":367},"obj":"Sentence"},{"id":"T47","span":{"begin":368,"end":601},"obj":"Sentence"},{"id":"T48","span":{"begin":602,"end":749},"obj":"Sentence"},{"id":"T49","span":{"begin":750,"end":837},"obj":"Sentence"},{"id":"T50","span":{"begin":838,"end":887},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Authors' conclusions\nThe individual signs and symptoms included in this review appear to have very poor diagnostic properties, although this should be interpreted in the context of selection bias and heterogeneity between studies. Based on currently available data, neither absence nor presence of signs or symptoms are accurate enough to rule in or rule out disease. Prospective studies in an unselected population presenting to primary care or hospital outpatient settings, examining combinations of signs and symptoms to evaluate the syndromic presentation of COVID‐19 disease, are urgently needed. Results from such studies could inform subsequent management decisions such as self‐isolation or selecting patients for further diagnostic testing. We also need data on potentially more specific symptoms such as loss of sense of smell. Studies in older adults are especially important."}

{"project":"LitCovid-PubTator","denotations":[{"id":"119","span":{"begin":455,"end":465},"obj":"Species"},{"id":"120","span":{"begin":709,"end":717},"obj":"Species"},{"id":"121","span":{"begin":563,"end":571},"obj":"Disease"}],"attributes":[{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"Tax:9606"},{"id":"A120","pred":"tao:has_database_id","subj":"120","obj":"Tax:9606"},{"id":"A121","pred":"tao:has_database_id","subj":"121","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Authors' conclusions\nThe individual signs and symptoms included in this review appear to have very poor diagnostic properties, although this should be interpreted in the context of selection bias and heterogeneity between studies. Based on currently available data, neither absence nor presence of signs or symptoms are accurate enough to rule in or rule out disease. Prospective studies in an unselected population presenting to primary care or hospital outpatient settings, examining combinations of signs and symptoms to evaluate the syndromic presentation of COVID‐19 disease, are urgently needed. Results from such studies could inform subsequent management decisions such as self‐isolation or selecting patients for further diagnostic testing. We also need data on potentially more specific symptoms such as loss of sense of smell. Studies in older adults are especially important."}