Id |
Subject |
Object |
Predicate |
Lexical cue |
T1285 |
0-21 |
Sentence |
denotes |
Study characteristics |
T1286 |
22-277 |
Sentence |
denotes |
Patient Sampling Purpose: diagnosis SARS‐CoV‐2 test positivesDesign: cross‐sectional, retrospective studyRecruitment: electronic health record data from the national Veterans Affairs Healthcare System ‐ national Corporate Data Warehouse (USA)Sample size: |
T1287 |
278-568 |
Sentence |
denotes |
3789 (585 cases)Inclusion criteria: all patients in the Veterans Affairs cohort, born between 1945 and 1965 and active in care, tested for COVID‐19 between 8 February and 30 March 2020Exclusion criteria: patients for whom results were pending (n = 93) or inconclusive (n = 33) were excluded |
T1288 |
569-719 |
Sentence |
denotes |
Patient characteristics and setting Facility cases: tested positive for SARS‐CoV‐2Facility controls: tested negative for SARS‐CoV‐2Country: USADates: |
T1289 |
720-847 |
Sentence |
denotes |
8 February 2020‐30 March 2020Symptoms and severity: all patients who were tested were includedDemographics: median age overall: |
T1290 |
848-882 |
Sentence |
denotes |
65.7 years (IQR 60.5‐70.7) (cases: |
T1291 |
883-904 |
Sentence |
denotes |
66.1 years, controls: |
T1292 |
905-940 |
Sentence |
denotes |
65.6 years);gender overall (M%/F%): |
T1293 |
941-1031 |
Sentence |
denotes |
90.2/9.8, cases 95.4/4.6, controls 89.2/10.8Exposure history: not specified (all over USA) |
T1294 |
1032-1078 |
Sentence |
denotes |
Index tests Hypoxia (oxygen saturation ≤ 93%) |
T1295 |
1079-1110 |
Sentence |
denotes |
Body temperature (3 categories) |
T1296 |
1111-1179 |
Sentence |
denotes |
Target condition and reference standard(s) TC: SARS‐CoV‐2 infection |
T1297 |
1180-1325 |
Sentence |
denotes |
RS: no data on reference PCR test used, multiple different reference tests used with unknown test characteristics (samples: nasopharyngeal swabs) |
T1298 |
1326-1371 |
Sentence |
denotes |
Flow and timing Time interval maximum 2 days |
T1299 |
1372-1386 |
Sentence |
denotes |
Comparative |
T1300 |
1387-1395 |
Sentence |
denotes |
Notes |
T1301 |
1396-1418 |
Sentence |
denotes |
Methodological quality |
T1302 |
1419-1484 |
Sentence |
denotes |
Item Authors' judgement Risk of bias Applicability concerns |
T1303 |
1485-1494 |
Sentence |
denotes |
DOMAIN 1: |
T1304 |
1495-1512 |
Sentence |
denotes |
Patient Selection |
T1305 |
1513-1569 |
Sentence |
denotes |
Was a consecutive or random sample of patients enrolled? |
T1306 |
1571-1580 |
Sentence |
denotes |
Yes |
T1307 |
1581-1615 |
Sentence |
denotes |
Was a case‐control design avoided? |
T1308 |
1617-1626 |
Sentence |
denotes |
Yes |
T1309 |
1627-1672 |
Sentence |
denotes |
Did the study avoid inappropriate exclusions? |
T1310 |
1674-1683 |
Sentence |
denotes |
Yes |
T1311 |
1684-1729 |
Sentence |
denotes |
Did the study avoid inappropriate inclusions? |
T1312 |
1731-1744 |
Sentence |
denotes |
Unclear |
T1313 |
1745-1814 |
Sentence |
denotes |
Could the selection of patients have introduced bias? Low risk |
T1314 |
1815-1921 |
Sentence |
denotes |
Are there concerns that the included patients and setting do not match the review question? Unclear |
T1315 |
1922-1931 |
Sentence |
denotes |
DOMAIN 2: |
T1316 |
1932-1954 |
Sentence |
denotes |
Index Test (All tests) |
T1317 |
1955-2054 |
Sentence |
denotes |
Were the index test results interpreted without knowledge of the results of the reference standard? |
T1318 |
2056-2069 |
Sentence |
denotes |
Unclear |
T1319 |
2070-2116 |
Sentence |
denotes |
If a threshold was used, was it pre‐specified? |
T1320 |
2118-2127 |
Sentence |
denotes |
Yes |
T1321 |
2128-2223 |
Sentence |
denotes |
Could the conduct or interpretation of the index test have introduced bias? Unclear risk |
T1322 |
2224-2346 |
Sentence |
denotes |
Are there concerns that the index test, its conduct, or interpretation differ from the review question? Low concern |
T1323 |
2347-2356 |
Sentence |
denotes |
DOMAIN 3: |
T1324 |
2357-2375 |
Sentence |
denotes |
Reference Standard |
T1325 |
2376-2453 |
Sentence |
denotes |
Is the reference standards likely to correctly classify the target condition? |
T1326 |
2455-2468 |
Sentence |
denotes |
Unclear |
T1327 |
2469-2569 |
Sentence |
denotes |
Were the reference standard results interpreted without knowledge of the results of the index tests? |
T1328 |
2571-2584 |
Sentence |
denotes |
Unclear |
T1329 |
2585-2691 |
Sentence |
denotes |
Could the reference standard, its conduct, or its interpretation have introduced bias? Unclear risk |
T1330 |
2692-2821 |
Sentence |
denotes |
Are there concerns that the target condition as defined by the reference standard does not match the question? Low concern |
T1331 |
2822-2831 |
Sentence |
denotes |
DOMAIN 4: |
T1332 |
2832-2847 |
Sentence |
denotes |
Flow and Timing |
T1333 |
2848-2924 |
Sentence |
denotes |
Was there an appropriate interval between index test and reference standard? |
T1334 |
2926-2935 |
Sentence |
denotes |
Yes |
T1335 |
2936-2989 |
Sentence |
denotes |
Did all patients receive the same reference standard? |
T1336 |
2991-3004 |
Sentence |
denotes |
Unclear |
T1337 |
3005-3048 |
Sentence |
denotes |
Were all patients included in the analysis? |
T1338 |
3050-3058 |
Sentence |
denotes |
No |
T1339 |
3059-3119 |
Sentence |
denotes |
Could the patient flow have introduced bias? Low risk |