Id |
Subject |
Object |
Predicate |
Lexical cue |
T1284 |
0-12 |
Sentence |
denotes |
Rentsch 2020 |
T1285 |
13-34 |
Sentence |
denotes |
Study characteristics |
T1286 |
35-290 |
Sentence |
denotes |
Patient Sampling Purpose: diagnosis SARS‐CoV‐2 test positivesDesign: cross‐sectional, retrospective studyRecruitment: electronic health record data from the national Veterans Affairs Healthcare System ‐ national Corporate Data Warehouse (USA)Sample size: |
T1287 |
291-581 |
Sentence |
denotes |
3789 (585 cases)Inclusion criteria: all patients in the Veterans Affairs cohort, born between 1945 and 1965 and active in care, tested for COVID‐19 between 8 February and 30 March 2020Exclusion criteria: patients for whom results were pending (n = 93) or inconclusive (n = 33) were excluded |
T1288 |
582-732 |
Sentence |
denotes |
Patient characteristics and setting Facility cases: tested positive for SARS‐CoV‐2Facility controls: tested negative for SARS‐CoV‐2Country: USADates: |
T1289 |
733-860 |
Sentence |
denotes |
8 February 2020‐30 March 2020Symptoms and severity: all patients who were tested were includedDemographics: median age overall: |
T1290 |
861-895 |
Sentence |
denotes |
65.7 years (IQR 60.5‐70.7) (cases: |
T1291 |
896-917 |
Sentence |
denotes |
66.1 years, controls: |
T1292 |
918-953 |
Sentence |
denotes |
65.6 years);gender overall (M%/F%): |
T1293 |
954-1044 |
Sentence |
denotes |
90.2/9.8, cases 95.4/4.6, controls 89.2/10.8Exposure history: not specified (all over USA) |
T1294 |
1045-1091 |
Sentence |
denotes |
Index tests Hypoxia (oxygen saturation ≤ 93%) |
T1295 |
1092-1123 |
Sentence |
denotes |
Body temperature (3 categories) |
T1296 |
1124-1192 |
Sentence |
denotes |
Target condition and reference standard(s) TC: SARS‐CoV‐2 infection |
T1297 |
1193-1338 |
Sentence |
denotes |
RS: no data on reference PCR test used, multiple different reference tests used with unknown test characteristics (samples: nasopharyngeal swabs) |
T1298 |
1339-1384 |
Sentence |
denotes |
Flow and timing Time interval maximum 2 days |
T1299 |
1385-1399 |
Sentence |
denotes |
Comparative |
T1300 |
1400-1408 |
Sentence |
denotes |
Notes |
T1301 |
1409-1431 |
Sentence |
denotes |
Methodological quality |
T1302 |
1432-1497 |
Sentence |
denotes |
Item Authors' judgement Risk of bias Applicability concerns |
T1303 |
1498-1507 |
Sentence |
denotes |
DOMAIN 1: |
T1304 |
1508-1525 |
Sentence |
denotes |
Patient Selection |
T1305 |
1526-1582 |
Sentence |
denotes |
Was a consecutive or random sample of patients enrolled? |
T1306 |
1584-1593 |
Sentence |
denotes |
Yes |
T1307 |
1594-1628 |
Sentence |
denotes |
Was a case‐control design avoided? |
T1308 |
1630-1639 |
Sentence |
denotes |
Yes |
T1309 |
1640-1685 |
Sentence |
denotes |
Did the study avoid inappropriate exclusions? |
T1310 |
1687-1696 |
Sentence |
denotes |
Yes |
T1311 |
1697-1742 |
Sentence |
denotes |
Did the study avoid inappropriate inclusions? |
T1312 |
1744-1757 |
Sentence |
denotes |
Unclear |
T1313 |
1758-1827 |
Sentence |
denotes |
Could the selection of patients have introduced bias? Low risk |
T1314 |
1828-1934 |
Sentence |
denotes |
Are there concerns that the included patients and setting do not match the review question? Unclear |
T1315 |
1935-1944 |
Sentence |
denotes |
DOMAIN 2: |
T1316 |
1945-1967 |
Sentence |
denotes |
Index Test (All tests) |
T1317 |
1968-2067 |
Sentence |
denotes |
Were the index test results interpreted without knowledge of the results of the reference standard? |
T1318 |
2069-2082 |
Sentence |
denotes |
Unclear |
T1319 |
2083-2129 |
Sentence |
denotes |
If a threshold was used, was it pre‐specified? |
T1320 |
2131-2140 |
Sentence |
denotes |
Yes |
T1321 |
2141-2236 |
Sentence |
denotes |
Could the conduct or interpretation of the index test have introduced bias? Unclear risk |
T1322 |
2237-2359 |
Sentence |
denotes |
Are there concerns that the index test, its conduct, or interpretation differ from the review question? Low concern |
T1323 |
2360-2369 |
Sentence |
denotes |
DOMAIN 3: |
T1324 |
2370-2388 |
Sentence |
denotes |
Reference Standard |
T1325 |
2389-2466 |
Sentence |
denotes |
Is the reference standards likely to correctly classify the target condition? |
T1326 |
2468-2481 |
Sentence |
denotes |
Unclear |
T1327 |
2482-2582 |
Sentence |
denotes |
Were the reference standard results interpreted without knowledge of the results of the index tests? |
T1328 |
2584-2597 |
Sentence |
denotes |
Unclear |
T1329 |
2598-2704 |
Sentence |
denotes |
Could the reference standard, its conduct, or its interpretation have introduced bias? Unclear risk |
T1330 |
2705-2834 |
Sentence |
denotes |
Are there concerns that the target condition as defined by the reference standard does not match the question? Low concern |
T1331 |
2835-2844 |
Sentence |
denotes |
DOMAIN 4: |
T1332 |
2845-2860 |
Sentence |
denotes |
Flow and Timing |
T1333 |
2861-2937 |
Sentence |
denotes |
Was there an appropriate interval between index test and reference standard? |
T1334 |
2939-2948 |
Sentence |
denotes |
Yes |
T1335 |
2949-3002 |
Sentence |
denotes |
Did all patients receive the same reference standard? |
T1336 |
3004-3017 |
Sentence |
denotes |
Unclear |
T1337 |
3018-3061 |
Sentence |
denotes |
Were all patients included in the analysis? |
T1338 |
3063-3071 |
Sentence |
denotes |
No |
T1339 |
3072-3132 |
Sentence |
denotes |
Could the patient flow have introduced bias? Low risk |