PMC:7381711 / 6453-7631
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T54 | 433-438 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
| T55 | 705-711 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
| T56 | 756-763 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T57 | 1105-1109 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T6 | 433-438 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
| T7 | 705-711 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T8 | 1105-1109 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 249 | 674-688 | Gene | denotes | thrombomodulin | Gene:7056 |
| 250 | 705-736 | Gene | denotes | tissue factor pathway inhibitor | Gene:7035 |
| 251 | 695-698 | Gene | denotes | AT3 | Gene:462 |
| 252 | 556-564 | Species | denotes | patients | Tax:9606 |
| 253 | 34-42 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 254 | 54-81 | Disease | denotes | coagulopathy and thromboses | MESH:D013927 |
| 255 | 114-138 | Disease | denotes | mortality of the disease | MESH:D003643 |
| 256 | 193-201 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 257 | 259-271 | Disease | denotes | coagulopathy | MESH:D001778 |
| 258 | 373-385 | Disease | denotes | coagulopathy | MESH:D001778 |
| 259 | 433-446 | Disease | denotes | organ failure | MESH:D009102 |
| 260 | 450-456 | Disease | denotes | sepsis | MESH:D018805 |
| 261 | 570-578 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 262 | 646-658 | Disease | denotes | coagulopathy | MESH:D001778 |
| 263 | 662-668 | Disease | denotes | sepsis | MESH:D018805 |
| 264 | 798-807 | Disease | denotes | mortality | MESH:D003643 |
| 265 | 849-861 | Disease | denotes | coagulopathy | MESH:D001778 |
| 266 | 890-902 | Disease | denotes | coagulopathy | MESH:D001778 |
| 267 | 934-940 | Disease | denotes | sepsis | MESH:D018805 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T62 | 34-42 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T63 | 54-66 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
| T64 | 71-81 | Disease | denotes | thromboses | http://purl.obolibrary.org/obo/MONDO_0000831 |
| T65 | 193-201 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T66 | 259-271 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
| T67 | 373-385 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
| T68 | 570-578 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T69 | 646-658 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
| T70 | 849-861 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
| T71 | 890-902 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T29 | 386-389 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T30 | 416-417 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T31 | 433-438 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
| T32 | 458-459 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T33 | 746-755 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
| T34 | 917-918 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T35 | 956-957 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T36 | 1105-1109 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T37 | 1105-1109 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T91 | 719-736 | Chemical | denotes | pathway inhibitor | http://purl.obolibrary.org/obo/CHEBI_76932 |
| T92 | 727-736 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T93 | 756-763 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T94 | 1156-1169 | Chemical | denotes | anticoagulant | http://purl.obolibrary.org/obo/CHEBI_50249 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 1027-1038 | http://purl.obolibrary.org/obo/GO_0050817 | denotes | coagulation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T43 | 0-139 | Sentence | denotes | Taken together, it is likely that COVID-19-associated coagulopathy and thromboses contribute to the morbidity and mortality of the disease. |
| T44 | 140-359 | Sentence | denotes | However, it is important to recognize that other non-COVID-19 critical illnesses have demonstrated similar evidence of coagulopathy, yet failed to benefit from anticoagulation treatment in randomized controlled studies. |
| T45 | 360-604 | Sentence | denotes | For example, coagulopathy has been widely recognized as a contributor to organ failure in sepsis, a disease characterized by circulating D-dimer concentrations that approximate levels observed in patients with COVID-19 (Fig. 2; 10, 32, 38, 40). |
| T46 | 605-862 | Sentence | denotes | However, studies that have targeted this coagulopathy in sepsis with thrombomodulin (40), AT3 (42), tissue factor pathway inhibitor (1), and activated protein C (31) have all failed to improve mortality, despite improving laboratory indexes of coagulopathy. |
| T47 | 863-991 | Sentence | denotes | These studies suggest that coagulopathy may simply be a consequence of sepsis, as opposed to a key pathogenic driver of disease. |
| T48 | 992-1178 | Sentence | denotes | Alternatively, as discussed below, coagulation may impart both harmful and protective effects within the injured lung, negating any clinical benefit (or harm) from anticoagulant therapy. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T14 | 54-66 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
| T15 | 259-271 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
| T16 | 373-385 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
| T17 | 450-456 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
| T18 | 646-658 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
| T19 | 662-668 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
| T20 | 849-861 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
| T21 | 890-902 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
| T22 | 934-940 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32519894-11236773-2138163 | 588-590 | 11236773 | denotes | 10 |
| 32519894-32320003-2138164 | 592-594 | 32320003 | denotes | 32 |
| 32519894-32220112-2138165 | 596-598 | 32220112 | denotes | 38 |
| 32519894-31104069-2138166 | 600-602 | 31104069 | denotes | 40 |
| 32519894-31104069-2138167 | 690-692 | 31104069 | denotes | 40 |
| 32519894-11597289-2138168 | 700-702 | 11597289 | denotes | 42 |
| 32519894-12851279-2138169 | 738-739 | 12851279 | denotes | 1 |
| 32519894-22616830-2138170 | 767-769 | 22616830 | denotes | 31 |