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PMC:7381711 / 2984-3953 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T17 0-7 Body_part denotes Heparin http://purl.org/sig/ont/fma/fma82839
T18 71-86 Body_part denotes heparan sulfate http://purl.org/sig/ont/fma/fma63023
T19 88-90 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T20 92-110 Body_part denotes glycosaminoglycans http://purl.org/sig/ont/fma/fma63011
T21 133-143 Body_part denotes intestines http://purl.org/sig/ont/fma/fma7199
T22 197-199 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T23 200-217 Body_part denotes glycosaminoglycan http://purl.org/sig/ont/fma/fma63011
T24 233-240 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T25 332-339 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T26 403-411 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T27 457-463 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T28 657-659 Body_part denotes HS http://purl.org/sig/ont/fma/fma63023
T29 762-769 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T30 770-777 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T31 930-937 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 133-143 Body_part denotes intestines http://purl.obolibrary.org/obo/UBERON_0000160

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
97 501-504 Gene denotes AT3 Gene:462
98 683-686 Gene denotes AT3 Gene:462
99 722-725 Gene denotes AT3 Gene:462
100 483-499 Gene denotes antithrombin-III Gene:462
101 0-7 Chemical denotes Heparin MESH:D006493
102 71-110 Chemical denotes heparan sulfate (HS) glycosaminoglycans
103 197-217 Chemical denotes HS glycosaminoglycan
104 233-240 Chemical denotes heparin MESH:D006493
105 332-339 Chemical denotes heparin MESH:D006493
106 457-463 Chemical denotes serine MESH:D012694
107 618-633 Chemical denotes pentasaccharide
108 762-769 Chemical denotes heparin MESH:D006493
109 930-937 Chemical denotes heparin MESH:D006493

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T8 11-12 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 133-143 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestines
T10 133-143 http://www.ebi.ac.uk/efo/EFO_0000834 denotes intestines
T11 538-546 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T12 567-575 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T13 608-609 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 818-821 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T21 0-7 Chemical denotes Heparin http://purl.obolibrary.org/obo/CHEBI_28304
T22 71-86 Chemical denotes heparan sulfate http://purl.obolibrary.org/obo/CHEBI_28815
T23 71-78 Chemical denotes heparan http://purl.obolibrary.org/obo/CHEBI_24500
T24 79-86 Chemical denotes sulfate http://purl.obolibrary.org/obo/CHEBI_16189
T25 88-90 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T27 92-110 Chemical denotes glycosaminoglycans http://purl.obolibrary.org/obo/CHEBI_18085
T28 197-199 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T30 200-217 Chemical denotes glycosaminoglycan http://purl.obolibrary.org/obo/CHEBI_18085
T31 233-240 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T32 332-339 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T33 403-411 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T34 457-482 Chemical denotes serine protease inhibitor http://purl.obolibrary.org/obo/CHEBI_64926
T35 457-463 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T36 464-482 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T38 473-482 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T39 524-537 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T40 553-566 Chemical denotes anticoagulant http://purl.obolibrary.org/obo/CHEBI_50249
T41 618-633 Chemical denotes pentasaccharide http://purl.obolibrary.org/obo/CHEBI_35369
T42 657-659 Chemical denotes HS http://purl.obolibrary.org/obo/CHEBI_74056|http://purl.obolibrary.org/obo/CHEBI_28815
T44 762-769 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T45 770-777 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T46 930-937 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 524-546 http://purl.obolibrary.org/obo/GO_0050819 denotes anticoagulant activity
T2 553-575 http://purl.obolibrary.org/obo/GO_0050819 denotes anticoagulant activity

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T22 0-157 Sentence denotes Heparin is a heterogeneous preparation of long, linear highly sulfated heparan sulfate (HS) glycosaminoglycans purified from porcine intestines (see Fig. 1).
T23 158-312 Sentence denotes The sulfated nature of its constituent HS glycosaminoglycan chains confers heparin with the highest negative charge density of any known biomolecule (43).
T24 313-547 Sentence denotes This charge allows heparin to strongly and selectively interact with an immense number of proteins, the most classic being its interaction with serine protease inhibitor antithrombin-III (AT3) that provides its anticoagulant activity.
T25 548-714 Sentence denotes This anticoagulant activity is dependent on the presence of a precise pentasaccharide sequence within longer HS chains that allows for AT3 binding as shown in Fig. 1.
T26 715-969 Sentence denotes Beyond AT3, hundreds of biologically relevant, heparin-protein interactions have been described, which has led to the recognition of an immense number of potential off-target (both positive and negative) effects of heparin of unknown clinical importance.

LitCovid-PD-GlycoEpitope

Id Subject Object Predicate Lexical cue glyco_epitope_db_id
T1 71-86 GlycoEpitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T2 88-90 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086
T3 197-199 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086
T4 657-659 GlycoEpitope denotes HS http://www.glycoepitope.jp/epitopes/EP0086

2_test

Id Subject Object Predicate Lexical cue
32519894-28653068-2138150 308-310 28653068 denotes 43